Structure and chain conformation of beta-glucan isolated from Auricularia auricula-judae.

abstract：:The oxidation of methionine to methionine sulfoxide both in vivo and in vitro can lead to the loss of biological activity in a variety of proteins. This loss of activity can be reversed by an enzyme called methionine sulfoxide reductase. The gene for this enzyme has been cloned and sequenced from a variety of prokaryo...

journal_title：Biopolymers

authors： Brot N,Weissbach H

更新日期：2000-01-01 00:00:00

abstract：:Increasing attention is being paid to the role of selenium, both as an essential component required for the activity of many enzymes and in the context of selenium-based pharmaceutical agents. A wide range of therapeutics that include selenium are on the market and under development, such as antihypertensive, anticanc...

journal_title：Biopolymers

authors： Hartman I,Raia CA,Zauhar RJ

更新日期：2006-12-15 00:00:00

abstract：:Vibrational absorption and vibrational circular dichroism (VCD) spectra of valinomycin are measured, in different solvents, in the ester and amide carbonyl stretching regions. The influence of cations, namely Li(+), Na(+), K(+), and Cs(+), in methanol-d(4) solvent is also investigated. Ab initio quantum mechanical cal...

journal_title：Biopolymers

authors： Wang F,Zhao C,Polavarapu PL

更新日期：2004-09-01 00:00:00

abstract：:Raman spectra of normal hair shafts and hair shafts from patients exhibiting trichothiodystrophy (TTD) were obtained using line focus laser illumination. Because hair from TTD patients has a significant decrease in the content of the sulfur-containing amino acids in comparison to normal hair, the 550-500 cm(-1) disulf...

journal_title：Biopolymers

authors： Schlücker S,Liang C,Strehle KR,DiGiovanna JJ,Kraemer KH,Levin IW

更新日期：2006-08-15 00:00:00

abstract：:The use of alpha,alpha-disubstituted amino acids represents a valuable strategy to exercise conformational control in peptides. Incorporation of the nonstereogenic alpha-aminoisobutyryl-glycyl (Aib-Gly) dipeptidyl sequence into i+1 and i+2 positions of an acyclic peptide sequence, originally designed and investigated ...

journal_title：Biopolymers

authors： Masterson LR,Etienne MA,Porcelli F,Barany G,Hammer RP,Veglia G

更新日期：2007-01-01 00:00:00

abstract：:We have previously described [K. M. Sullivan and D. M. J. Lilley (1986) Cell 47, 817-827] a set of sequences, called C-type inducing sequences, which cause cruciform extrusion by adjacent inverted repeats to occur by an abnormal kinetic pathway involving a large denatured region of DNA. In this paper we apply statisti...

journal_title：Biopolymers

authors： Schaeffer F,Yeramian E,Lilley DM

更新日期：1989-08-01 00:00:00

abstract：:Shorter analogues of a continuous epitope of hepatitis A virus, VP3(110-121) peptide, failed to react with convalescent sera, indicating the importance of the entire peptide in the epitope structure. To better understand the influence of the structural properties of this 12-mer peptide epitope on its biological activi...

journal_title：Biopolymers

authors： Sospedra P,Muñoz M,García M,Alsina MA,Mestres C,Haro I

更新日期：2000-12-01 00:00:00

abstract：:Actinomycin-D (actD) binds to natural DNA at two different classes of binding sites, weak and strong. The affinity for these sites is highly dependent on DNA sequence and solution conditions, and the interaction appears to be purely entropic driven. Although the entropic character of this reaction has been attributed ...

journal_title：Biopolymers

authors： Ruggiero Neto J,Colombo MF

更新日期：2000-01-01 00:00:00

abstract：:Calcium ions (Ca(2+) ) play key roles in various fundamental biological processes such as cell signaling and brain function. Molecular dynamics (MD) simulations have been used to study such interactions, however, the accuracy of the Ca(2+) models provided by the standard MD force fields has not been rigorously tested....

journal_title：Biopolymers

authors： Yoo J,Wilson J,Aksimentiev A

更新日期：2016-10-01 00:00:00

abstract：:Synthetic RNA poly[r(A-T)] has been synthesized and its CD spectral properties compared to those of poly[r(A-U)], poly[d(A-T)], and poly[d(A-U)] in various salt and ethanolic solutions. The CD spectra of poly[r(A-T)] in an aqueous buffer and of poly[d(A-T)] in 70.8% v/v ethanol are very similar, suggesting that they b...

journal_title：Biopolymers

authors： Vorlícková M,Kypr J,Jovin TM,Planck M

更新日期：1990-02-05 00:00:00

abstract：:Proteins and nucleic acids are able to adopt their native conformation and perform their biological role only in the presence of water with which they actively interact in a mutually modifying way. Traditionally, hydrophobic effect has been considered to be the major factor stabilizing biopolymeric structures. However...

journal_title：Biopolymers

authors： Chalikian TV

更新日期：2003-12-01 00:00:00

abstract：:The presence of non-native kinetic traps in the free energy landscape of a protein may significantly lengthen the overall folding time so that the folding process becomes unreliable. We use a computational model alpha-helical hairpin peptide to calculate structural free energy landscapes and relate them to the kinetic...

journal_title：Biopolymers

authors： Chapagain PP,Gerstman BS

更新日期：2006-02-15 00:00:00

abstract：:New optical nanoresonance effects enabled us to study the effect of ions on nanometric carbohydrate thin layers on chips. Immobilization was done via spin coating of the derivatized carbohydrate polymer at a metallized chip surface forming ultrathin films (about 50-300 nm thick) followed by photochemical cross-linking...

journal_title：Biopolymers

authors： Palkovits R,Mayer C,Bauer G,Winkler H,Pittner F,Schalkhammer T

更新日期：2003-07-01 00:00:00

abstract：:Useful methods of protein labeling via functional peptide tags have been developed in the field of proteome and chemical biology. New tag-probe pairs based on leucine zipper peptides for labeling target proteins are described. These consist of an α-helical probe peptide with an environmental-sensitive fluorescent dye ...

journal_title：Biopolymers

authors： Nomura W,Mino T,Narumi T,Ohashi N,Masuda A,Hashimoto C,Tsutsumi H,Tamamura H

更新日期：2010-01-01 00:00:00

abstract：:A novel heptapeptide comprising Ile-Gln-Ser-Pro-His-Phe-Phe (IQSPHFF) identified and found to undergo self-assembly into microparticles in solution. To understand the effects of ultraviolet (UV) irradiation on the self-assembly process, IQSPHFF solutions were exposed to the UV light of 365 nm at room temperature. This...

journal_title：Biopolymers

authors： Wei R,Jin CC,Quan J,Nie HL,Zhu LM

更新日期：2014-03-01 00:00:00

abstract：:Peptide-conjugated polysaccharide matrices using bioactive laminin-derived peptides are useful biomaterials for tissue and cell engineering. Here, we demonstrate an easy handling preparation method for peptide-polysaccharide matrices using polyion complex with both alginate and chitosan. First, aldehyde-alginate was s...

journal_title：Biopolymers

authors： Fujimori C,Kumai J,Nakamura K,Gu Y,Katagiri F,Hozumi K,Kikkawa Y,Nomizu M

更新日期：2017-01-01 00:00:00

abstract：:To investigate the mechanism leading to the reduction in tensile strength of permanent waved human hair, the structure of cross-sections at various depths of permanent waved white human hair was directly analyzed without isolating the cuticle and cortex, using Raman spectroscopy. The beta-sheet and/or random coil cont...

journal_title：Biopolymers

authors： Kuzuhara A

更新日期：2007-02-15 00:00:00

abstract：:Many studies have examined consensus sequences required for protein-glycosaminoglycan interactions. Through the synthesis of helical heparin binding peptides, this study probes the relationship between spatial arrangement of positive charge and heparin binding affinity. Peptides with a linear distribution of positive ...

journal_title：Biopolymers

authors： Rullo A,Nitz M

更新日期：2010-03-01 00:00:00

abstract：:In the first two papers of this series, the tools necessary to evaluate substrate ring deformations were developed, and then the modeling of short amylose fragments (maltotriose and maltopentaose) inside the catalytic site of barley alpha-amylase was performed. In this third paper, this docking has been extended to th...

journal_title：Biopolymers

authors： André G,Buléon A,Haser R,Tran V

更新日期：1999-12-01 00:00:00

abstract：:In this study a novel general approach is presented that allows for a straightforward design of receptor binding assays. This principle of a receptor binding assay is applied to the estrogen receptor, which is important in the management of breast cancer and for the estimation of the estrogenic potency of chemicals in...

journal_title：Biopolymers

authors： Christoph S,Meyer-Almes FJ

更新日期：2003-01-01 00:00:00

abstract：:We describe a method to determine the magnitude of protein-induced DNA bends relative to a set of standard A tract bends using comparative gel electrophoresis. The DNA bend of interest was that induced by the catabolite activator protein (CAP), the transcriptional activator protein of the lac operon. The set of compar...

journal_title：Biopolymers

authors： Zinkel SS,Crothers DM

更新日期：1990-01-01 00:00:00

abstract：:The transient electric birefringence of two small DNA restriction fragments of the same molecular weight, one of which migrates anomalously slowly on polyacrylamide gels, has been investigated. Both fragments exhibit negative birefringence. The decay of the birefringence of the anomalously slowly migrating fragment is...

journal_title：Biopolymers

authors： Stellwagen NC

更新日期：1991-11-01 00:00:00

abstract：:A model of protein-chaperone interaction as a two-phase (unfolding/refolding) iterative annealing mechanism able to promote structural segregation of hydrophobic and hydrophilic monomers and thereby facilitate access to nativelike states has recently been applied successfully to two 22-mers of the Honeycutt and Thirum...

journal_title：Biopolymers

authors： Gorse D

更新日期：2002-07-15 00:00:00

abstract：:Surface-enhanced Raman spectroscopy (SERS) in a silver sol assisted by density functional theory (DFT) calculations is shown to be a promising tool in the characterization of platinum complexes and their interaction with nucleic acid bases. This is demonstrated using cisplatin and guanine as a model. The energies and ...

journal_title：Biopolymers

authors： Giese B,McNaughton D

更新日期：2003-01-01 00:00:00

abstract：:Physiological properties of soluble antigen-antibody (Ag-Ab) complexes depend in part on the size of the complexes. In previous work, the size distribution and structure of model Ag-Ab complexes were determined by electron microscopy. In this study, we used constrained regularization analysis of quasi-elastic light sc...

journal_title：Biopolymers

authors： Murphy RM,Yarmush ML,Colton CK

更新日期：1991-10-01 00:00:00

abstract：:The quantum yield for cyclobutyl-pyrimidine dimerization in DNA has been observed to increase approximately linearly with increasing pyrimidine tract length. A model without adjustable parameters for this yield is proposed based on energy delocalization, vibronic symmetry switching, and saturation statistics that desc...

journal_title：Biopolymers

authors： Texter J

更新日期：1992-01-01 00:00:00

abstract：:The de novo design of peptides and proteins has emerged as an approach for investigating protein structure and function. The success relies heavily on the ability to design relatively short peptides that can adopt stable secondary structures. To this end, substitution with α,β-dehydroamino acids, especially α,β-didehy...

journal_title：Biopolymers

authors： Gupta M,Chauhan VS

更新日期：2011-03-01 00:00:00

abstract：:This paper is a personal recollection of some of the events and research that surrounded the amino acid sequence determination of the hypothalamic releasing factor, TRF (now known as TRH), by mass spectrometry (MS), and the development of reverse phase high performance liquid chromatography (RP-HPLC) MS and tandem MS ...

journal_title：Biopolymers

authors： Desiderio DM

更新日期：1996-01-01 00:00:00

abstract：:We have studied by Raman and ir spectroscopy the structure of self-associated polyinosinic acid and polyguanylic acid in aqueous solution. The results are consistent with the formation of a four-stranded complex, which melts cooperatively near 60 degrees C in the case of poly(I) in the presence of K+ ions. The conform...

journal_title：Biopolymers

authors： Simard C,Savoie R

更新日期：1994-01-01 00:00:00

abstract：:Aqueous solutions of DNA fragments with a contour length (500 A) near the persistence length at DNA concentrations ranging from 10 to 290 mg/mL solvent and a constant supporting electrolyte concentration of 0.01 M (predominantly NaCl) were examined by 23Na-nmr spectroscopy at temperatures of 20, 40, and 60 degrees C. ...

journal_title：Biopolymers

authors： Strzelecka TE,Rill RL

更新日期：1990-01-01 00:00:00