Abstract:
:The quantum yield for cyclobutyl-pyrimidine dimerization in DNA has been observed to increase approximately linearly with increasing pyrimidine tract length. A model without adjustable parameters for this yield is proposed based on energy delocalization, vibronic symmetry switching, and saturation statistics that describe the average number of (base pairwise) breathing modes in a given tract of pyrimidines. This average number of modes is an approximately linear function of the tract length. Monte Carlo techniques are used to simulate base sequences and photochemical events, and indicate that this model is consistent with experiment for Tetrahymena pyriformis DNA.
journal_name
Biopolymersjournal_title
Biopolymersauthors
Texter Jdoi
10.1002/bip.360320108subject
Has Abstractpub_date
1992-01-01 00:00:00pages
53-9issue
1eissn
0006-3525issn
1097-0282journal_volume
32pub_type
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