Effect of chain length of HAV-VP3 synthetic peptides on its interaction with biomembrane models.

abstract：:Amyloid aggregates have been implicated in the pathogenesis of diseases such as type 2 diabetes, Alzheimer's, Parkinson's, and prion disease. Recently determined microcrystal structures of several short peptide segments derived from fibril-forming proteins revealed coexistence of alternative aggregation modes (amyloid...

journal_title：Biopolymers

authors： Berhanu WM,Masunov AE

更新日期：2012-01-01 00:00:00

abstract：:Cytochrome c3 from Desulfovibrio gigas is electrostatically adsorbed on Ag electrodes coated with self-assembled monolayers (SAMs) of 11-mercaptoundecanoic acid. The redox equilibria and electron transfer dynamics of the adsorbed four-heme protein are studied by surface enhanced resonance Raman spectroscopy. Immobiliz...

journal_title：Biopolymers

authors： Simaan AJ,Murgida DH,Hildebrandt P

更新日期：2002-01-01 00:00:00

abstract：:A series of CD measurements were carried out on members of peptides in the endothelin and sarafotoxin families. The helical structures taken by these peptides containing the helical motif with the sequences of Cys-X-X-X-Cys and Cys-X-Cys [Y. Kobayashi et al. (1991) Neurochemistry International Vol. 18, pp. 525-534] ar...

journal_title：Biopolymers

authors： Tamaoki H,Kyogoku Y,Nakajima K,Sakakibara S,Hayashi M,Kobayashi Y

更新日期：1992-04-01 00:00:00

abstract：:Different hexameric forms of insulin have been crystallized from a variety of conditions. In the presence of 1% phenol, 1.0 M sodium chloride, and at a pH of 8.5, a rhombohedral form is produced with two monomers in the asymmetric unit, space group R3, a = 79.92 A and c = 40.39 A. The structure has been solved and ref...

journal_title：Biopolymers

authors： Smith GD,Dodson GG

更新日期：1992-04-01 00:00:00

abstract：:The elucidation of structure-function relationships in insoluble elastin is often approached using elastin-like polypeptides. In this manner, the characterization of the different regions in this extensive biopolymer may be facilitated in a "piece-wise" manner. Our solid-state NMR experiments indicate that (LGGVG)n ha...

journal_title：Biopolymers

authors： Kumashiro KK,Kurano TL,Niemczura WP,Martino M,Tamburro AM

更新日期：2003-10-01 00:00:00

abstract：:Amyloid fibrils are considered to play causal roles in the pathogenesis of amyloid-related degenerative diseases such as Alzheimer's disease, type II diabetes mellitus, the transmissible spongiform encephalopathies, and prion disease. The mechanism of fibril formation is still hotly debated and remains an important op...

journal_title：Biopolymers

authors： Chen Y,He YJ,Wu M,Yan G,Li Y,Zhang J,Chen HF

更新日期：2010-06-01 00:00:00

abstract：:Normal mode calculations have been done on a range of disulfide bridge conformations in order to determine how the SS stretch and CS stretch frequencies depend on structure. In addition to varying the C alpha C beta SS and NC alpha C beta S dihedral angles, we have varied the phi, psi of the adjoining peptide groups s...

journal_title：Biopolymers

authors： Qian W,Krimm S

更新日期：1992-08-01 00:00:00

abstract：:The dissociation and assembly of quadruplex DNA structures (and a few quadruplex RNAs) have been characterized at several levels of rigor, ranging from gross descriptions of factors that govern each process, to semiquantitative comparisons of the relative abilities of these factors to induce stabilization or destabili...

journal_title：Biopolymers

authors： Hardin CC,Perry AG,White K

更新日期：2000-01-01 00:00:00

abstract：:In this article, we review current knowledge about the silk produced by the larvae of bees, ants, and hornets [Apoidea and Vespoidea: Hymenoptera]. Different species use the silk either alone or in composites for a variety of purposes including mechanical reinforcement, thermal regulation, or humidification. The chara...

journal_title：Biopolymers

authors： Sutherland TD,Weisman S,Walker AA,Mudie ST

更新日期：2012-06-01 00:00:00

abstract：:The methods used to study the relative reaction rates of 45 different aliphatic and aromatic carboxylic acids when coupled to resin-bound amino acid amides is described. Competition experiments involving the coupling of incoming carboxylic acids to resin-bound amino acid amides were performed. The relative composition...

journal_title：Biopolymers

authors： Acharya AN,Ostresh JM,Houghten RA

更新日期：2002-10-05 00:00:00

abstract：:The physicochemical characteristics of the green fluorescent protein (GFP), including the thermodynamic properties (entropy, enthalpy, Gibbs' free energy, heat capacity), normal mode vibrations, and atomic fluctuations, were investigated. The Gaussian 03 computational chemistry program was employed for normal mode ana...

journal_title：Biopolymers

authors： Krasnenko V,Tkaczyk AH,Tkaczyk ER,Farkas O,Mauring K

更新日期：2005-06-15 00:00:00

abstract：:Raman spectra of normal hair shafts and hair shafts from patients exhibiting trichothiodystrophy (TTD) were obtained using line focus laser illumination. Because hair from TTD patients has a significant decrease in the content of the sulfur-containing amino acids in comparison to normal hair, the 550-500 cm(-1) disulf...

journal_title：Biopolymers

authors： Schlücker S,Liang C,Strehle KR,DiGiovanna JJ,Kraemer KH,Levin IW

更新日期：2006-08-15 00:00:00

abstract：:We studied fluorescence enhancements of fluorescein tethered to silver colloids of different size. Thiolated 23-mer oligonucleotide (ss DNA-SH) was bound selectively to silver colloids deposited on 3-aminopropyltriethoxysilane (APS)-treated quartz slides. Fluorescein-labeled complementary oligonucleotide (ss Fl-DNA) w...

journal_title：Biopolymers

authors： Lukomska J,Malicka J,Gryczynski I,Leonenko Z,Lakowicz JR

更新日期：2005-01-01 00:00:00

abstract：:Targeting double-stranded DNA with homopyrimidine PNAs results in strand displacement complexes PNA/DNA/PNA rather than PNA/DNA/DNA triplex structures. Not much is known about the binding properties of DNA-PNA chimeras. A 16-mer 5'-DNA-3'-p-(N)PNA(C) has been investigated for its ability to hybridize a complementary d...

journal_title：Biopolymers

authors： Petraccone L,Erra E,Messere A,Montesarchio D,Piccialli G,De Napoli L,Barone G,Giancola C

更新日期：2004-03-01 00:00:00

abstract：:Combinatorial chemistry has recently burst on the scene as a valuable tool for the discovery of new drug candidates. The ability to synthesize hundreds of compounds for screening is a useful complement to rational drug design. There are many similarities between the design of new therapeutic agents and the development...

journal_title：Biopolymers

authors： Agarkov A,Greenfield S,Xie D,Pawlick R,Starkey G,Gilbertson SR

更新日期：2006-01-01 00:00:00

abstract：:An increasing number of RNAs are being discovered that perform their functions by undergoing large changes in conformation in response to a variety of cellular signals, including recognition of proteins and small molecular targets, changes in temperature, and RNA synthesis itself. The measurement of NMR residual dipol...

journal_title：Biopolymers

authors： Getz M,Sun X,Casiano-Negroni A,Zhang Q,Al-Hashimi HM

更新日期：2007-08-05 00:00:00

abstract：:The synthetic peptide of sequence H-Ala-Ser-Thr-Thr-Thr-Asn-Tyr-Thr-OH, termed peptide T, a competitor of the Human Immunodeficiency Virus in the binding to human T cells, and its C-terminal pentapeptide fragment, were studied by 1H-nmr in DMSO solution to determine conformational preferences. The observation of nucle...

journal_title：Biopolymers

authors： Motta A,Picone D,Temussi PA,Marastoni M,Tomatis R

更新日期：1989-01-01 00:00:00

abstract：:Suppressors of Cytokine Signaling (SOCS) proteins are negative regulators of JAK proteins that are receptor-associated tyrosine kinases, which play key roles in the phosphorylation and subsequent activation of several transcription factors named STATs. Unlike the other SOCS proteins, SOCS1 and 3 show, in the N-termina...

journal_title：Biopolymers

authors： La Manna S,Lopez-Sanz L,Leone M,Brandi P,Scognamiglio PL,Morelli G,Novellino E,Gomez-Guerrero C,Marasco D

更新日期：2017-11-20 00:00:00

abstract：:Aromatic stacking and hydrogen bonding between nucleobases are two of the key interactions responsible for stabilization of DNA double-helical structures. The present work aims at defining the specific contributions of these interactions to the stability of individual base pairs in DNA. The two DNA double helices inve...

journal_title：Biopolymers

authors： Every AE,Russu IM

更新日期：2007-10-05 00:00:00

abstract：:Near uv CD spectra of Trp residues in proteins frequently show a complex line shape deriving from the overlap of 1La and 1Lb electronic transitions. This study presents an original empirical method of resolving these components, based on the near uv CD spectra of well-defined complexes of calmodulin domains with targe...

journal_title：Biopolymers

authors： Barth A,Martin SR,Bayley PM

更新日期：1998-06-01 00:00:00

abstract：:The mode coupling diffusion theory is applied to the derivation of local dynamics in proteins in solution. The rotational dynamics of the bonds along the protein sequence are calculated and compared to the experimentally measured nmr (15)N spin-lattice relaxation time T(1), at 36.5, 60.8, and 81.1 MHz of the vnd/NK-2 ...

journal_title：Biopolymers

authors： La Penna G,Fausti S,Perico A,Ferretti JA

更新日期：2000-08-01 00:00:00

abstract：:The present study characterizes the unfolding and folding processes of recombinant manganese peroxidase. This enzyme contains five disulfide bonds, two calcium ions, and one heme prosthetic group. Circular dichroism in the far UV was used to monitor global changes of the protein secondary structure, whereas UV-visible...

journal_title：Biopolymers

authors： Banci L,Bartalesi I,Ciofi-Baffoni S,Tien M

更新日期：2003-01-01 00:00:00

abstract：:Circular dichroism using synchrotron radiation (SRCD) can extend the spectral range down to approximately 130 nm for dry proteins, potentially providing new structural information. Using a selection of dried model proteins, including alpha-helical, beta-sheet, and mixed-structure proteins, we observe a low-wavelength ...

journal_title：Biopolymers

authors： Nesgaard LW,Hoffmann SV,Andersen CB,Malmendal A,Otzen DE

更新日期：2008-09-01 00:00:00

abstract：:With the availability of accurate methods to treat the electrostatic long-range interactions, molecular dynamics simulations have resulted in refined dynamical models of the structure of the hydration shell around RNA motifs. The models reviewed here range from basic Watson-Crick to more specific noncanonical base pai...

journal_title：Biopolymers

authors： Auffinger P,Westhof E

更新日期：2000-01-01 00:00:00

abstract：:Among the most exciting functional features of G-protein coupled receptors (GPCRs) that are coming into focus lately are those relating to the role and structural characteristics of their oligomerization (mostly homo- and heterodimers). The structural underpinnings of these novel functional insights are still not clea...

journal_title：Biopolymers

authors： Filizola M,Weinstein H

更新日期：2002-01-01 00:00:00

abstract：:The oxidation of methionine to methionine sulfoxide both in vivo and in vitro can lead to the loss of biological activity in a variety of proteins. This loss of activity can be reversed by an enzyme called methionine sulfoxide reductase. The gene for this enzyme has been cloned and sequenced from a variety of prokaryo...

journal_title：Biopolymers

authors： Brot N,Weissbach H

更新日期：2000-01-01 00:00:00

abstract：:A Monte Carlo method has been developed for generating the conformations of short single-stranded DNAs from arbitrary starting states. The chain conformers are constructed from energetically favorable arrangements of the constituent mononucleotides. Minimum energy states of individual dinucleotide monophosphate molecu...

journal_title：Biopolymers

authors： Erie DA,Breslauer KJ,Olson WK

更新日期：1993-01-01 00:00:00

abstract：:To optimize antigen-antibody reactions, we have synthesized chemically well-defined hydrophilic microspheres. Proteins or haptens were covalently linked to these carriers. When the microsphere conjugates were agglutinated by the corresponding antiserum, the size of the complex artificially increased during the immunol...

journal_title：Biopolymers

authors： Marchand J,Varcin P,Riochet D,Montagne P,Cuilliere ML,Duheille J,Pau B

更新日期：1992-08-01 00:00:00

abstract：:The conformation and intermolecular association of [D-Hyi2, L-Hyi4] meso-valinomycin [cyclo[-D-Val-D-Hyi-L-Val-L-Hyi-(D-Val-L-Hyi-L-Val-D-+ ++Hyi)2-], C60H102N6O18] in a crystal form obtained from ethanol solution has been determined by x-ray crystallography. Two depsipeptides and one ethanol molecule per asymmetric u...

journal_title：Biopolymers

authors： Pletnev VZ,Ivanov VT,Langs DA,Burkhart BM,Duax WL

更新日期：1997-11-01 00:00:00

abstract：:An unusual class of nanoscopic, ring-shaped, single-walled biopolymers arises when alphabeta-tubulin is mixed with certain small peptides obtained from various marine organisms and cyanobacteria. The single-ring structures, whose mean molecular weight depends on the specific peptide added to the reaction mixture, usua...

journal_title：Biopolymers

authors： Boukari H,Sackett DL,Schuck P,Nossal RJ

更新日期：2007-08-05 00:00:00