Long-term benefit of postconditioning.

abstract：:The two-dimensional echocardiographic features of three patients with congenital aneurysms of the left atrium are described. The aneurysm arose from the left atrial appendage in two patients and from the posterior left atrial wall in one. The aneurysms were characterized by their origin from an otherwise normal left a...

journal_title：Circulation

authors： Foale RA,Gibson TC,Guyer DE,Gillam L,King ME,Weyman AE

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Recent transcatheter aortic valve replacement studies have raised concerns about adverse cerebrovascular events. The etiopathology of the embolized material is currently unknown. METHODS AND RESULTS:A total of 40 patients underwent transcatheter aortic valve replacement with the use of a dual filter-based e...

journal_title：Circulation

authors： Van Mieghem NM,Schipper ME,Ladich E,Faqiri E,van der Boon R,Randjgari A,Schultz C,Moelker A,van Geuns RJ,Otsuka F,Serruys PW,Virmani R,de Jaegere PP

更新日期：2013-06-04 00:00:00

abstract：BACKGROUND:The cross-talk between vascular endothelial growth factor (VEGF)-A, angiopoietin (Ang), and VE-cadherin coregulates endothelial cell (EC) survival. Cardiac expression of VEGF-A but not its receptor KDR is blunted in dilated cardiomyopathy (DCM). Whether VE-cadherin/Ang function is affected in DCM is unknown....

journal_title：Circulation

authors： Schäfer R,Abraham D,Paulus P,Blumer R,Grimm M,Wojta J,Aharinejad S

更新日期：2003-09-30 00:00:00

abstract：:We report noninvasive and invasive studies designed to clarify the mechanism of the third heart sound (S3) in humans. The noninvasive observations were made using a miniature accelerometer attached to the skin surface at the cardiac apex. In subjects with no S3, the tracings were either flat or showed very low undulat...

journal_title：Circulation

authors： Ozawa Y,Smith D,Craige E

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Clinical detection of transplant rejection by repeated endomyocardial biopsy requires catheterization and entails risks. Recently developed molecular and cellular imaging techniques that visualize macrophage host responses could provide a noninvasive alternative. Yet, which macrophage functions may provide u...

journal_title：Circulation

authors： Christen T,Nahrendorf M,Wildgruber M,Swirski FK,Aikawa E,Waterman P,Shimizu K,Weissleder R,Libby P

更新日期：2009-04-14 00:00:00

abstract：:To determine how survival and clinical status were related to left ventricular (LV) size and systolic function after mitral valve replacement, 104 patients (48 mitral regurgitation [MR], 33 mitral stenosis [MS], and 23 MS/MR) with isolated mitral valve replacement were evaluated before and after surgery. Preoperative ...

journal_title：Circulation

authors： Crawford MH,Souchek J,Oprian CA,Miller DC,Rahimtoola S,Giacomini JC,Sethi G,Hammermeister KE

更新日期：1990-04-01 00:00:00

abstract：:Sequential control angiographic examinations were performed at 2 weeks, 1 year, 5 to 7 years, and 10 to 12 years after aortocoronary saphenous vein bypass surgery in 82 unselected patients. Graft modifications consisting of wall irregularities and obstructive lesions of various severity and shapes that were found to d...

journal_title：Circulation

authors： Campeau L,Enjalbert M,Lespérance J,Vaislic C,Grondin CM,Bourassa MG

更新日期：1983-09-01 00:00:00

abstract：BACKGROUND:Age is an important determinant of outcomes for patients with acute coronary syndromes (ACS); however, community practice reveals a disproportionately lower use of cardiovascular medications and invasive treatment even among elderly patients with ACS who would stand to benefit. Reasons include limited trial ...

journal_title：Circulation

authors： Alexander KP,Newby LK,Cannon CP,Armstrong PW,Gibler WB,Rich MW,Van de Werf F,White HD,Weaver WD,Naylor MD,Gore JM,Krumholz HM,Ohman EM,American Heart Association Council on Clinical Cardiology.,Society of Geriatric Cardiology

更新日期：2007-05-15 00:00:00

abstract：BACKGROUND:Age-adjusted stroke incidence has decreased over the past 50 years, likely as a result of changes in the prevalence and impact of various stroke risk factors. An updated version of the Framingham Stroke Risk Profile (FSRP) might better predict current risks in the FHS (Framingham Heart Study) and other cohor...

journal_title：Circulation

authors： Dufouil C,Beiser A,McLure LA,Wolf PA,Tzourio C,Howard VJ,Westwood AJ,Himali JJ,Sullivan L,Aparicio HJ,Kelly-Hayes M,Ritchie K,Kase CS,Pikula A,Romero JR,D'Agostino RB,Samieri C,Vasan RS,Chêne G,Howard G,Seshadri S

更新日期：2017-03-21 00:00:00

abstract：BACKGROUND:Evidence suggests that the vessel wall contains an oxidase similar, if not identical, to phagocytic NADPH oxidase. We tested the contribution of this specific oxidase to the progression of atherosclerosis and the regulation of blood pressure. METHODS AND RESULTS:An examination of aortic rings from wild-type...

journal_title：Circulation

authors： Hsich E,Segal BH,Pagano PJ,Rey FE,Paigen B,Deleonardis J,Hoyt RF,Holland SM,Finkel T

更新日期：2000-03-21 00:00:00

abstract：BACKGROUND:Lymphatic network and chemokine-mediated signals are essential for leukocyte traffic during the proximal steps of alloimmune response. We aimed to determine the role of lymphatic vessels and their principal growth signaling pathway, vascular endothelial growth factor (VEGF)-C/D/VEGFR-3, during acute and chro...

journal_title：Circulation

authors： Nykänen AI,Sandelin H,Krebs R,Keränen MA,Tuuminen R,Kärpänen T,Wu Y,Pytowski B,Koskinen PK,Ylä-Herttuala S,Alitalo K,Lemström KB

更新日期：2010-03-30 00:00:00

abstract：BACKGROUND:In the congenital long-QT syndrome (LQTS), there can be a marked phenotypic heterogeneity. Founder effects, by which many individuals share a mutation identical by descent, represent a powerful tool to further understand the underlying mechanisms and to predict the natural history of mutation-associated effe...

journal_title：Circulation

authors： Brink PA,Crotti L,Corfield V,Goosen A,Durrheim G,Hedley P,Heradien M,Geldenhuys G,Vanoli E,Bacchini S,Spazzolini C,Lundquist AL,Roden DM,George AL Jr,Schwartz PJ

更新日期：2005-10-25 00:00:00

abstract：BACKGROUND:Contrary to expectation, most studies have demonstrated that initiation of an angiotensin-converting enzyme (ACE) inhibitor in conventional doses in patients with heart failure reduces the diuretic efficacy of furosemide. Recently, it has been suggested that single low doses (1 mg) but not high doses (25 mg)...

journal_title：Circulation

authors： Good JM,Brady AJ,Noormohamed FH,Oakley CM,Cleland JG

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Patients with congenital heart disease (CHD) and heterotaxy show high postsurgical morbidity/mortality, with some developing respiratory complications. Although this finding is often attributed to the CHD, airway clearance and left-right patterning both require motile cilia function. Thus, airway ciliary dys...

journal_title：Circulation

authors： Nakhleh N,Francis R,Giese RA,Tian X,Li Y,Zariwala MA,Yagi H,Khalifa O,Kureshi S,Chatterjee B,Sabol SL,Swisher M,Connelly PS,Daniels MP,Srinivasan A,Kuehl K,Kravitz N,Burns K,Sami I,Omran H,Barmada M,Olivier K,

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Coronary spastic angina (CSA) is a common disease among East Asians, including Japanese. The prevalence of alcohol flushing syndrome associated with deficient activity of the variant aldehyde dehydrogenase 2 (ALDH2*2) genotype is prevalent among East Asians. We examined whether CSA is associated with the ALD...

journal_title：Circulation

authors： Mizuno Y,Harada E,Morita S,Kinoshita K,Hayashida M,Shono M,Morikawa Y,Murohara T,Nakayama M,Yoshimura M,Yasue H

更新日期：2015-05-12 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of dilated cardiomyopathy (DCM). TNF-alpha-converting enzyme (TACE) has recently been purified and its complementary DNA cloned. The expression of TACE results in the production of a functional enzyme that has precursor TNF-alpha...

journal_title：Circulation

authors： Satoh M,Nakamura M,Saitoh H,Satoh H,Maesawa C,Segawa I,Tashiro A,Hiramori K

更新日期：1999-06-29 00:00:00

abstract：:Study of the detailed pathology of the myocardium and coronary arteries in ambulatory subjects dying suddenly of coronary heart disease shows that they can be divided into two groups. In one group, there is atherosclerosis with a new vascular event involving coronary thrombosis, which initiates acute myocardial ischem...

journal_title：Circulation

authors： Davies MJ

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Patients with bicuspid aortic valve (AV) stenosis were excluded from the pivotal evaluations of transcatheter AV replacement (TAVR) devices. We sought to evaluate the outcomes of TAVR in patients with bicuspid AV stenosis in comparison with those with tricuspid AV stenosis. METHODS:We used data from the Soc...

journal_title：Circulation

authors： Halim SA,Edwards FH,Dai D,Li Z,Mack MJ,Holmes DR,Tuzcu EM,Thourani VH,Harrison JK,Brennan JM

更新日期：2020-03-31 00:00:00

abstract：BACKGROUND:The quantity and intensity of physical activity required for the primary prevention of coronary heart disease (CHD) remain unclear. Therefore, we examined the association of the quantity and intensity of physical activity with CHD risk and the impact of other coronary risk factors. METHODS AND RESULTS:We fo...

journal_title：Circulation

authors： Sesso HD,Paffenbarger RS Jr,Lee IM

更新日期：2000-08-29 00:00:00

abstract：BACKGROUND:Randomized trials that studied clinical outcomes after percutaneous coronary intervention (PCI) with bare metal stenting versus coronary artery bypass grafting (CABG) are underpowered to properly assess safety end points like death, stroke, and myocardial infarction. Pooling data from randomized controlled t...

journal_title：Circulation

authors： Daemen J,Boersma E,Flather M,Booth J,Stables R,Rodriguez A,Rodriguez-Granillo G,Hueb WA,Lemos PA,Serruys PW

更新日期：2008-09-09 00:00:00

abstract：BACKGROUND:New methods of R-R interval variability based on fractal scaling and nonlinear dynamics ("chaos theory") may give new insights into heart rate dynamics. The aims of this study were to (1) systematically characterize and quantify the effects of aging from early childhood to advanced age on 24-hour heart rate ...

journal_title：Circulation

authors： Pikkujämsä SM,Mäkikallio TH,Sourander LB,Räihä IJ,Puukka P,Skyttä J,Peng CK,Goldberger AL,Huikuri HV

更新日期：1999-07-27 00:00:00

abstract：:Exercise trials in cardiology are often hindered by inconsistent approaches to exercise testing. These inconsistencies include the choice of exercise protocol, exercise end points, points of analysis, and absence or misuse of gas exchange data. Gas exchange techniques greatly enhance the accuracy with which cardiopulm...

journal_title：Circulation

authors： Myers J,Froelicher VF

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:We assessed the role of glucose and insulin in the regulation of circulating levels of soluble intercellular adhesion molecule-1 (sICAM-1) and vascular adhesion molecule-1 (sVCAM-1) in normal subjects and in patients with type 2 diabetes. METHODS AND RESULTS:Plasma glucose concentrations were acutely raised...

journal_title：Circulation

authors： Marfella R,Esposito K,Giunta R,Coppola G,De Angelis L,Farzati B,Paolisso G,Giugliano D

更新日期：2000-05-16 00:00:00

abstract：BACKGROUND:Adenosine has several potentially cardioprotective effects. We hypothesized that the effects of endogenous adenosine vary with degree of ischemia and that elevating endogenous levels is protective. METHODS AND RESULTS:Isolated blood-perfused piglet hearts underwent 120 minutes of low-flow ischemia (10% flow...

journal_title：Circulation

authors： Sommerschild HT,Grund F,Offstad J,Jynge P,Ilebekk A,Kirkebøen KA

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Creation of a complete bidirectional inferior vena cava-tricuspid annulus isthmus block (CBIB) by radiofrequency catheter ablation is now a well-accepted criterion for prevention of common atrial flutter (AFl) recurrences. However, some patients still complain of palpitations after ablation, and it is not kn...

journal_title：Circulation

authors： Anselme F,Saoudi N,Poty H,Douillet R,Cribier A

更新日期：1999-02-02 00:00:00

abstract：BACKGROUND:Although the left prepectoral site is preferred for "hot can" placement, this site is unavailable in some patients. We evaluated the influence of electrode location on defibrillation thresholds with alternative hot can and transvenous lead configurations. METHODS AND RESULTS:Three interrelated studies were ...

journal_title：Circulation

authors： Yamanouchi Y,Mowrey KA,Niebauer MJ,Tchou PJ,Wilkoff BL

更新日期：1997-12-16 00:00:00

abstract：BACKGROUND:Chronic orthostatic intolerance (COI) is a debilitating autonomic condition in young adults. Its neurohumoral and hemodynamic profiles suggest possible alterations of postural sympathetic function and of baroreflex control of heart rate (HR). METHODS AND RESULTS:In 16 COI patients and 16 healthy volunteers,...

journal_title：Circulation

authors： Furlan R,Jacob G,Snell M,Robertson D,Porta A,Harris P,Mosqueda-Garcia R

更新日期：1998-11-17 00:00:00

abstract：BACKGROUND:Depletion of L-arginine (L-arg), the substrate for nitric oxide (NO) synthesis, could be one of the mechanisms responsible for the reduced production of NO and decreased coronary flow (CF) during reperfusion. This, in turn, may adversely affect mechanical function. We aimed to study the benefits of exogenous...

journal_title：Circulation

authors： Amrani M,Gray CC,Smolenski RT,Goodwin AT,London A,Yacoub MH

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:Pulmonary arterial hypertension (PAH) is a life-threatening disease, characterized by vascular smooth muscle cell hyperproliferation. The calcium/calmodulin-dependent phosphodiesterase 1 (PDE1) may play a major role in vascular smooth muscle cell proliferation. METHODS AND RESULTS:We investigated the expres...

journal_title：Circulation

authors： Schermuly RT,Pullamsetti SS,Kwapiszewska G,Dumitrascu R,Tian X,Weissmann N,Ghofrani HA,Kaulen C,Dunkern T,Schudt C,Voswinckel R,Zhou J,Samidurai A,Klepetko W,Paddenberg R,Kummer W,Seeger W,Grimminger F

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Perivascular adipose tissue (PVAT) surrounds most vessels and shares common features with brown adipose tissue (BAT). Although adaptive thermogenesis in BAT increases energy expenditure and is beneficial for metabolic diseases, little is known about the role of PVAT in vascular diseases such as atheroscleros...

journal_title：Circulation

authors： Chang L,Villacorta L,Li R,Hamblin M,Xu W,Dou C,Zhang J,Wu J,Zeng R,Chen YE

更新日期：2012-08-28 00:00:00