Effect of meteorological variables on the incidence of respiratory tract infections.

abstract：:Recent developments in intrabronchial administration of insulin raise lung function in patients with type I diabetes as important issue. Several studies in adults report abnormalities of lung function of these patients. The aim of this study was to investigate lung function in children with type I diabetes. Twenty-sev...

journal_title：Respiratory medicine

authors： van Gent R,Brackel HJ,de Vroede M,van der Ent CK

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Obstructive sleep apnea (OSA) is a disorder characterized by repetitive obstructions of the upper airway. Individuals with OSA experience intermittent hypoxia, hypercapnia, and arousals during sleep, resulting in increased sympathetic activation. Chemoreflex activation, arising from the resultant oscillatory...

journal_title：Respiratory medicine

authors： Hargens TA,Guill SG,Aron A,Zedalis D,Gregg JM,Nickols-Richardson SM,Herbert WG

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Long-term corticosteroid use may increase cataract risk. The Lens Opacities Classification System (LOCS) III ranked lens opacities as Class 1: 0.5-0.9 unit; Class 2: 1.0-1.4 units; or Class 3: ≥1.5 units in clinical trials of combined mometasone furoate and formoterol (MF/F) administered by metered-dose inha...

journal_title：Respiratory medicine

authors： Maspero J,Cherrez I,Doherty DE,Tashkin DP,Kuna P,Kuo WL,Gates D,Nolte H,Chylack LT Jr

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Patients with idiopathic pulmonary fibrosis (IPF) present an important ventilatory limitation reducing their exercise capacity. Non-invasive ventilatory support has been shown to improve exercise capacity in patients with obstructive diseases; however, its effect on IPF patients remains unknown. OBJECTIVE:T...

journal_title：Respiratory medicine

authors： Moderno EV,Yamaguti WP,Schettino GP,Kairalla RA,Martins MA,Carvalho CR,Carvalho CR

更新日期：2010-01-01 00:00:00

abstract：:In this study we aimed to estimate direct medical costs of Chronic Obstructive Pulmonary Disease (COPD) by disease type; chronic bronchitis and emphysema. This study estimates direct costs in 1996 dollars using a prevalence approach and both aggregate and microcosting. A societal perspective is taken using prevalence,...

journal_title：Respiratory medicine

authors： Wilson L,Devine EB,So K

更新日期：2000-03-01 00:00:00

abstract：:The HandiHaler is a novel breath-actuated dry powder system designed for the delivery of tiotropium 18microg daily in the treatment of COPD. We compared patient ability to use the HandiHaler or metered dose inhaler (MDI) device correctly 4 weeks after receiving brief instructions and device demonstration. A single-bli...

journal_title：Respiratory medicine

authors： Dahl R,Backer V,Ollgaard B,Gerken F,Kesten S

更新日期：2003-10-01 00:00:00

abstract：:Exposure to air pollution is associated with adverse health effects, with particulate matter (PM) and ozone (O(3)) both indicated to be of considerable importance. Diesel engine exhaust (DE) and O(3) generate substantial inflammatory effects in the airways. However, as yet it has not been determined whether a subseque...

journal_title：Respiratory medicine

authors： Bosson J,Pourazar J,Forsberg B,Adelroth E,Sandström T,Blomberg A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Bronchiectasis (BQs) is an uncommon disease with the potential to cause devastating complications. All patients with BQs have cough and chronic sputum production that may have a great impact on patient's quality of life. Upper airway symptoms are also frequent in patients with BQs. Associations between upper...

journal_title：Respiratory medicine

authors： Guilemany JM,Alobid I,Angrill J,Ballesteros F,Bernal-Sprekelsen M,Picado C,Mullol J

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:Non-cystic fibrosis(CF) bronchiectasis has been recognized in children for the past 200 years. Early childhood pneumonia and underlying conditions such as immunodeficiency, primary ciliary dyskinesia(PCD), and congenital lung pathology should be considered in the etiology. The aim of our study was to descr...

journal_title：Respiratory medicine

authors： Satırer O,Mete Yesil A,Emiralioglu N,Tugcu GD,Yalcın E,Dogru D,Kiper N,Ozcelik U

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:IL-4 receptor alpha chain is crucial for the binding and signaling of IL-4, which mediates isotype switching and IgE production. The gene of IL-4 receptor alpha chain is a candidate gene for asthma and atopy. OBJECTIVES:To determine whether Ile50Val and Q576R polymorphisms of IL-4 receptor alpha chain gene ...

journal_title：Respiratory medicine

authors： Zhang W,Zhang X,Qiu D,Sandford A,Tan WC

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Anti-CADM-140 antibody (anti-CADM-140), also referred to as anti-melanoma differentiation-associated gene 5 (MDA5) antibody, is a myositis-specific antibody identified in the sera of patients with clinically amyopathic dermatomyositis (C-ADM) and is associated with a worse prognosis in dermatomyositis-associ...

journal_title：Respiratory medicine

authors： Tanizawa K,Handa T,Nakashima R,Kubo T,Hosono Y,Watanabe K,Aihara K,Oga T,Chin K,Nagai S,Mimori T,Mishima M

更新日期：2011-09-01 00:00:00

abstract：:The N(2) slope is an index of inhomogeneous distribution of ventilation and has been suggested to be suited for early testing of chronic obstructive pulmonary disease (COPD) in smokers. The aim of the present study was to examine the association between the fraction of exhaled nitric oxide (FENO) and the N(2) slope in...

journal_title：Respiratory medicine

authors： Olin AC,Andelid K,Vikgren J,Rosengren A,Larsson S,Bake B,Ekberg-Jansson A

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Although pulmonary rehabilitation (PR) improves function in people with chronic obstructive pulmonary disease (COPD), a community-based exercise program may be necessary to maintain functional capacity. We aimed to determine the effectiveness of a post-rehabilitation, community-based maintenance program on exer...

journal_title：Respiratory medicine

authors： Butler SJ,Desveaux L,Lee AL,Beauchamp MK,Brusco NK,Wang W,Goldstein RS,Brooks D

更新日期：2020-01-01 00:00:00

abstract：INTRODUCTION:Idiopathic bronchiectasis is a poorly defined disease characterised by persistent inflammation, infection and progressive lung damage. Natural killer (NK) cells provide a major defense against infection, through the interaction of their surface receptors, including the activating and inhibitory killer immu...

journal_title：Respiratory medicine

authors： McDonnell MJ,Anwar GA,Rutherford RM,De Soyza A,Worthy S,Corris PA,Lordan JL,Bourke S,Afolabi G,Ward C,Middleton P,Middleton D

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The development of pulmonary hypertension (PH) and its effect on long-term survival in bronchiectasis subjects has not been explored. The present study aims to analyze the factors associated with PH and its effect on long-term survival in bronchiectasis subjects. METHODS:We prospectively evaluated 23 bronch...

journal_title：Respiratory medicine

authors： Öcal S,Portakal O,Öcal A,Demir AU,Topeli A,Çöplü L

更新日期：2016-10-01 00:00:00

abstract：:Although in the clinic the presence of mucus in the airways is known to be an important factor influencing the sound of coughing in pathological conditions, this observation has not been established experimentally. We have substituted mucus in the airways of anaesthetized cats with 0.5 ml of natural undiluted egg albu...

journal_title：Respiratory medicine

authors： Korpás J,Widdicombe JG,Vrabec M

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate whether smokers with incidental findings of interstitial lung abnormalities have an increased mortality during long-term follow-up, and review the contributing causes of death. METHODS:Baseline CT scans of 1990 participants from the Danish Lung Cancer Screening Trial ...

journal_title：Respiratory medicine

authors： Hoyer N,Wille MMW,Thomsen LH,Wilcke T,Dirksen A,Pedersen JH,Saghir Z,Ashraf H,Shaker SB

更新日期：2018-03-01 00:00:00

abstract：:Nasal mucociliary clearance is a primary defense mechanism of the upper airways and may be acutely affected by nasal continuous positive airway pressure (nCPAP). nCPAP treatment is effective and safe. However, it can cause nasal side effects and contribute to a low compliance to the treatment. The aim of this study wa...

journal_title：Respiratory medicine

authors： de Oliveira LR,Albertini Yagi CS,Figueiredo AC,Saldiva PH,Lorenzi-Filho G

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:To determine the efficacy of oral theophylline compared with placebo in people with stable chronic obstructive pulmonary disease (COPD). METHODS:Systematic review of randomized-controlled trials comparing oral theophylline with placebo for a minimum of 7 days in people with stable COPD. RESULTS:Twenty rand...

journal_title：Respiratory medicine

authors： Ram FS,Jardin JR,Atallah A,Castro AA,Mazzini R,Goldstein R,Lacasse Y,Cendon S

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:Acid gastro-esophageal reflux has been shown associated with chronic pulmonary diseases. The role of non-acid refluxes in these children is still unknown. Therefore we investigated the prevalence of acid and non-acid refluxes, and their association with desaturations, in children with chronic pulmonary sympt...

journal_title：Respiratory medicine

authors： Thilmany C,Beck-Ripp J,Griese M

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:We investigated the adverse events (AEs) and treatment completion rates of a 3 month course of once-weekly isoniazid and rifapentine (3H1P1) in South Korean health care workers (HCWs) with latent tuberculosis infection (LTBI). METHODS:HCWs who were candidates for LTBI treatment were enrolled from two tertiary ...

journal_title：Respiratory medicine

authors： Jo KW,Kim JS,Kwon HS,Park YE,Kim JY,Hong MJ,Shim TS

更新日期：2019-01-01 00:00:00

abstract：:Several clinical trials have shown that the inhaled beta2-agonists with long-acting properties, formoterol and salmeterol, may be effective in acute exacerbations of chronic obstructive pulmonary disease (COPD). However, there is a great deal of controversy regarding the timing and optimal dose of inhaled beta2-agonis...

journal_title：Respiratory medicine

authors： Cazzola M,Santus P,Matera MG,Carlucci P,Belloli E,Di Marco F,Centanni S

更新日期：2003-05-01 00:00:00

abstract：:Summary beta2-adrenoreceptor agonists are able to modulate various aspects of airway cell functions involved in the inflammatory and repair processes characterizing a variety of respiratory disorders. Human bronchial epithelial cells (HBECs), which can act as immune effector cells and express beta2-adrenoreceptors, we...

journal_title：Respiratory medicine

authors： Sabatini F,Silvestri M,Sale R,Serpero L,Di Blasi P,Rossi GA

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Hospitalization attributed to severe exacerbations is the major cost driver of Chronic Obstructive Pulmonary Disease (COPD). Given that in Greece no previous studies have addressed the economic burden of COPD, the aim of the study was to examine the hospitalization cost of COPD patients with severe exacerbat...

journal_title：Respiratory medicine

authors： Geitona M,Hatzikou M,Steiropoulos P,Alexopoulos EC,Bouros D

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:There are no validated patient diaries for evaluating respiratory symptoms in idiopathic pulmonary fibrosis (IPF). PURPOSE:To evaluate the performance properties of the chronic obstructive pulmonary disease (COPD) Evaluating Respiratory Symptoms™ (E-RS™: COPD) measure in patients with IPF. METHODS:Concept ...

journal_title：Respiratory medicine

authors： Bacci ED,O'Quinn S,Leidy NK,Murray L,Vernon M

更新日期：2018-01-01 00:00:00

abstract：:Limited knowledge exists about development of bronchial hyperresponsiveness (BHR) through adolescence. We aimed to assess changes in and risk factors for BHR in adolescence. From a Norwegian birth cohort 517 subjects underwent clinical examinations, structured interviews and methacholine challenges at age 10 and 16. B...

journal_title：Respiratory medicine

authors： Riiser A,Hovland V,Mowinckel P,Carlsen KH,Carlsen KL

更新日期：2012-02-01 00:00:00

abstract：:This multi-centre, randomized, double-blind, double-dummy, parallel-group study was designed to investigate the hypothesis of equivalent efficacy and comparable safety of two inhaled presentations of salmeterol/fluticasone propionate combination product (SALM/FP) 50/100 microg administered twice daily to patients with...

journal_title：Respiratory medicine

authors： Bateman ED,Silins V,Bogolubov M

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The synergistic interactions between pharmacotherapy and pulmonary rehabilitation has been provided, but it remains to be established whether this may also apply to more severe patients. OBJECTIVES:We have examined whether tiotropium enhances the effects of exercise training in patients with advanced COPD (...

journal_title：Respiratory medicine

authors： Pasqua F,Biscione G,Crigna G,Auciello L,Cazzola M

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The effect of pro-inflammatory stimuli on bronchoconstrictor-induced air trapping has not been studied. OBJECTIVE:To determine the effect of natural allergen exposure, a pro-inflammatory stimulus, on methacholine- and adenosine 5'-monophospate (AMP)-induced air trapping. METHODS:Airway responsiveness to me...

journal_title：Respiratory medicine

authors： Lopez V,Prieto L,Perez C,Barato D,Marin J

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Pulmonary rehabilitation is very effective in improving exercise capacity, dyspnea and quality of life in the small group of patients with moderate to severe COPD. Given that little is known about exercise training in the large group of patients with mild to moderate COPD, we assessed the effectiveness of an...

journal_title：Respiratory medicine

authors： Fastenau A,van Schayck OC,Winkens B,Aretz K,Gosselink R,Muris JW

更新日期：2020-01-01 00:00:00