当前位置： SCI文献检索 > RESPIRATORY MEDICINE期刊下所有文献 > Evaluation of a respiratory symptom diary for clinical studies of idiopathic pulmonary fibrosis.

Evaluation of a respiratory symptom diary for clinical studies of idiopathic pulmonary fibrosis.

Abstract：

BACKGROUND:There are no validated patient diaries for evaluating respiratory symptoms in idiopathic pulmonary fibrosis (IPF). PURPOSE:To evaluate the performance properties of the chronic obstructive pulmonary disease (COPD) Evaluating Respiratory Symptoms™ (E-RS™: COPD) measure in patients with IPF. METHODS:Concept elicitation and cognitive interviews were conducted with IPF patients to evaluate content validity, including comprehensiveness, relevance, and interpretability of E-RS™ items in this patient population. Secondary analyses of IPF clinical study data were performed to evaluate the scoring structure of the tool. With modifications, reliability, validity, and responsiveness of the instrument (E-RS™: IPF) were evaluated. RESULTS:Qualitative interviews (n = 30) were conducted. During the elicitation interviews (n = 20), concept saturation for IPF respiratory symptoms was achieved; all respiratory symptoms covered by the E-RS™ were endorsed by ≥ 30% of the sample. During cognitive interviews (n = 10), all participants found the items interpretable and relevant. Factor analyses conducted via secondary analysis of IPF clinical study data identified no total score and four symptom scales: Chest, Breathlessness, Cough, and Sputum. Reliability of each scale was high (internal consistency [α] >0.85); 2-day reproducibility (ICC >0.88). Validity was supported through significant (P < 0.0001) relationships with the St. George's Respiratory Questionnaire (SGRQ), the University of California, San Diego Shortness of Breath Questionnaire (UCSD-SOBQ), and other variables. The scales were responsive to change when evaluated using SGRQ Symptoms, UCSD-SOBQ, and Patient Global Impression of Change as anchors (P < 0.01 to P < 0.0001). CONCLUSION:The E-RS™: IPF is a valid, reliable, and responsive tool for evaluating respiratory symptoms in patients with IPF.

journal_name

Respir Med

journal_title

Respiratory medicine

authors

Bacci ED,O'Quinn S,Leidy NK,Murray L,Vernon M

doi

10.1016/j.rmed.2017.11.011

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

130-138

eissn

0954-6111

issn

1532-3064

pii

S0954-6111(17)30392-X

journal_volume

134

pub_type

杂志文章

相关文献

RESPIRATORY MEDICINE文献大全
  • Bronchoalveolar lavage for the diagnosis of Pulmonary Langerhans cell histiocytosis.

    abstract：BACKGROUND:The histologic diagnosis of Pulmonary Langerhans cell histiocytosis (PLCH) is invasive and can cause complications. To confirm the diagnosis of PLCH, guidelines therefore recommend measuring CD1a-positive bronchoalveolar lavage fluid (BALF) cells despite its poor sensitivity and specificity. Thus, an improve...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2016.09.004

    authors： Lommatzsch M,Bratke K,Stoll P,Mülleneisen N,Prall F,Bier A,Virchow JC

    更新日期：2016-10-01 00:00:00

  • Prophylactic use of noninvasive ventilation in patients undergoing lung resectional surgery.

    abstract：QUESTION OF THE STUDY:We studied whether prophylactic use of noninvasive pressure support ventilation (NIPSV) administered pre- and postoperatively may reduce the postoperative pulmonary function impairment. PATIENTS AND METHODS:Prospective randomized clinical trial. Thirty-nine patients with a preoperative FEV(1) <70...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2006.12.002

    authors： Perrin C,Jullien V,Vénissac N,Berthier F,Padovani B,Guillot F,Coussement A,Mouroux J

    更新日期：2007-07-01 00:00:00

  • Regular albuterol or nedocromil sodium--effects on airway subepithelial tenascin in asthma.

    abstract：:Both albuterol and nedocromil sodium have been recognized to possess certain anti-inflammatory properties. However, there are no data on the impact of these drugs on the pathophysiology of the bronchial extracellular matrix in asthma characterized by enhanced tenascin (Tn) expression, known to occur proportional to th...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0954-6111(99)90086-0

    authors： Altraja A,Laitinen A,Meriste S,Marran S,Märtson T,Sillastu H,Laitinen LA

    更新日期：1999-07-01 00:00:00

  • Efficacy and safety of once-daily fluticasone furoate/vilanterol (100/25 mcg) versus twice-daily fluticasone propionate/salmeterol (250/50 mcg) in COPD patients.

    abstract：BACKGROUND:Fluticasone furoate/vilanterol (FF/VI) is an inhaled corticosteroid/long-acting beta2-agonist (ICS/LABA), recently approved as once-daily maintenance therapy for COPD. We compared the lung function effects of FF/VI with those of twice-daily fluticasone propionate/salmeterol (FP/SAL). METHODS:Three 12 week s...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.rmed.2014.05.008

    authors： Dransfield MT,Feldman G,Korenblat P,LaForce CF,Locantore N,Pistolesi M,Watkins ML,Crim C,Martinez FJ

    更新日期：2014-08-01 00:00:00

  • Changes in airway hyperresponsiveness following smoking cessation: comparisons between Mch and AMP.

    abstract：BACKGROUND:Given the observed association between smoking, inflammation and airway hyperresponsiveness (AHR) one may predict that smoking cessation may improve AHR. However, only a few studies have investigated the effect of smoking on AHR and their results appear to be conflicting depending on the stimulus used in the...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.09.004

    authors： Piccillo G,Caponnetto P,Barton S,Russo C,Origlio A,Bonaccorsi A,Di Maria A,Oliveri C,Polosa R

    更新日期：2008-02-01 00:00:00

  • Prevalence and prognosis of respiratory muscle weakness in heart failure patients with preserved ejection fraction.

    abstract：BACKGROUND:Although respiratory muscle weakness (RMW) is known to predict prognosis in patients with heart failure with reduced ejection fraction (HFrEF), RMW prevalence and its prognosis in those with preserved ejection fraction (HFpEF) remain unknown. We aimed to investigate whether the RMW predicted mortality in HFp...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.105834

    authors： Hamazaki N,Kamiya K,Matsuzawa R,Nozaki K,Ichikawa T,Tanaka S,Nakamura T,Yamashita M,Maekawa E,Noda C,Yamaoka-Tojo M,Matsunaga A,Masuda T,Ako J

    更新日期：2020-01-01 00:00:00

  • Effects of inspiratory muscle training on postural stability, pulmonary function and functional capacity in children with cystic fibrosis: A randomised controlled trial.

    abstract：BACKGROUND:Previous research has found conflictive results regarding the benefits of inspiratory muscle training (IMT) for cystic fibrosis (CF) patients. Also, involvement of postural stability is a rising concern in chronic lung diseases but its role in CF patients is poorly understood. Our aim was to investigate the ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2019.01.013

    authors： Zeren M,Cakir E,Gurses HN

    更新日期：2019-03-01 00:00:00

  • Effects of two types of equal-intensity inspiratory muscle training in stable patients with chronic obstructive pulmonary disease: A randomised controlled trial.

    abstract：PURPOSE:We conducted a randomised controlled trial to assess the effects of daily breathing pattern changes to stable patients with COPD excluding the confounding factors of inspiratory muscle mobilization, by ensuring the load intensities of two inspiratory training devices were equal. PATIENTS AND METHODS:Sixty pati...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2017.10.001

    authors： Wu W,Guan L,Zhang X,Li X,Yang Y,Guo B,Ou Y,Lin L,Zhou L,Chen R

    更新日期：2017-11-01 00:00:00

  • Chest low-dose computed tomography in neutropenic acute myeloid leukaemia patients.

    abstract：BACKGROUND:We aimed to compare chest low-dose computed tomography (LDCT) with chest radiography (CXR) in the assessment of febrile acute myeloid leukaemia neutropenic patients. METHODS:A prospective non-randomized study was carried out between 30 May, 2003 and 3 June, 2004 in consecutive neutropenic patients who requi...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2009.11.003

    authors： Patsios D,Maimon N,Chung T,Roberts H,Disperati P,Minden M,Paul N

    更新日期：2010-04-01 00:00:00

  • Adenosine deaminase activity in bronchoalveolar lavage in Turkish patients with smear negative pulmonary tuberculosis.

    abstract：:The sputum smear-negative patients have been a diagnostic challenge for health professionals. Adenosine deaminase (ADA) activity has been shown to rise in various body fluids of patients with tuberculosis (Tb). A prospective clinical trial was conducted to determine the diagnostic value of ADA activity in bronchoalveo...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1053/rmed.2001.1284

    authors： Kayacan O,Karnak D,Delibalta M,Beder S,Karaca L,Tutkak H

    更新日期：2002-07-01 00:00:00

  • IL-5, IL-8 and MMP -9 levels in exhaled breath condensate of atopic and nonatopic asthmatic children.

    abstract：RATIONALE:Asthma is a heterogeneous disease, and a great majority of pediatric patients with asthma demonstrate atopic characteristics and develop a Th2 type cytokine response. Nonatopic asthma, on the other hand, is seen more rarely. METHODS:In this study, levels of IL-5, IL-8 and MMP-9 were measured in exhaled breat...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2015.04.004

    authors： Turkeli A,Yilmaz O,Taneli F,Horasan GD,Kanik ET,Kizilkaya M,Gozukara C,Yuksel H

    更新日期：2015-06-01 00:00:00

  • The effect of inhaled terbutaline on FEV1, FVC, dyspnoea and walking distance in patients with chronic obstructive lung disease.

    abstract：:This double-blind, placebo-controlled, crossover study was performed to evaluate the effect of terbutaline administered by a turbuhaler on spirometry, walking distance and dyspnoea during exercise in patients with chronic obstructive lung disease (COLD) and to evaluate relationships between changes in spirometry and w...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0954-6111(06)80221-0

    authors： Evald T,Keittelmann S,Sindrup JH,Lange P

    更新日期：1992-03-01 00:00:00

  • Light smoking and dependence symptoms in high-school students.

    abstract：:In high-school students, prevalence of smoking is high but few studies analyzed smoking in the student population according to nicotine content of smoked cigarettes and gender. We analyzed the responses to a questionnaire, including the modified Fagerström Tolerance Questionnaire (FTQ), administered to 555 students (3...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2005.02.006

    authors： Soresi S,Catalano F,Spatafora M,Bonsignore MR,Bellia V

    更新日期：2005-08-01 00:00:00

  • Tumor necrosis factor receptors (TNFRs) on T lymphocytes and soluble TNFRs in different clinical courses of sarcoidosis.

    abstract：INTRODUCTION:The release of tumor necrosis factor (TNF-alpha) is increased in sarcoidosis patients. TNF-alpha exerts its effect by binding to specific cell surface receptors. There are only fragmentary data concerning the expression of tumor necrosis factor receptors (TNFRs) on bronchoalveolar lavage fluid (BALF) and p...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2006.06.004

    authors： Kieszko R,Krawczyk P,Chocholska S,Bojarska-Junak A,Jankowska O,Król A,Roliński J,Milanowski J

    更新日期：2007-03-01 00:00:00

  • COPD care programme can reduce readmissions and in-patient bed days.

    abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease worldwide with significant morbidity and mortality. AIM:To investigate the effect of a comprehensive COPD management programme in decreasing COPD readmissions 1 year before and 1 year after the programme. METHOD:185 (166 males) patients admit...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2014.09.019

    authors： Ko FW,Ngai JC,Ng SS,Chan KP,Cheung R,Leung MY,Pun MC,Hui DS

    更新日期：2014-12-01 00:00:00

  • The expression of pro- and anti-apoptotic Bcl-2 family proteins in peribronchiolar lymphocytes from patients with diffuse panbronchiolitis.

    abstract：:Diffuse panbronchiolitis (DPB) is a distinctive form of small airway disease, which is characterized by chronic inflammation with lymphocyte infiltration around bronchioles. The aim of this study was to evaluate the importance of factors related to apoptosis in peribronchiolar lymphocytes of DPB. We employed immunohis...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2006.02.011

    authors： Kadota J,Mizunoe S,Mukae H,Mito K,Kishi K,Tokimatsu I,Nagai H,Tomono K,Kohno S,Nasu M

    更新日期：2006-11-01 00:00:00

  • IL-4/IFN-γ inflammatory cytokine profile induces a deficient regulation of the IL-1β/IL-1RI/EP2/COX-2 pathway in nasal mucosa.

    abstract：BACKGROUND:We hypothesized that the peculiar mixed interleukin-4 (IL-4/Th2) and interferon gamma INF-γ (INF-γ/Th1) inflammatory milieu found in the airways of patients with aspirin-exacerbated respiratory disease (AERD) is responsible for the altered regulation of the IL-1β/IL-1RI-/EP2/COX-2 autocrine loop also found i...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2019.03.008

    authors： Machado-Carvalho L,Roca-Ferrer J,Picado C

    更新日期：2019-04-01 00:00:00

  • Do patients using long-term liquid oxygen differ from those on traditional treatment with oxygen concentrators and/or compressed gas cylinders? A comparison of two national registers.

    abstract：:Long-term oxygen therapy (LTOT) in patients with chronic hypoxaemia is an expanding field. Traditional stationary oxygen, with and without portable compressed gas cylinders, and portable liquid oxygen equipment is available today. No official guidelines exist for the prescription of liquid oxygen vs traditional oxygen...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(98)90037-3

    authors： Schaanning J,Strøm K,Boe J

    更新日期：1998-01-01 00:00:00

  • The need to improve inhalation technique in Europe: a report from the Aerosol Drug Management Improvement Team.

    abstract：:Although the principles of asthma management are well established in Europe, the available data indicate that asthma in patients is not well controlled. Many patients derive incomplete benefit from their inhaled medication because they do not use inhaler devices correctly and this may compromise asthma control. The Ae...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,评审

    doi：10.1016/j.rmed.2006.01.008

    authors： Crompton GK,Barnes PJ,Broeders M,Corrigan C,Corbetta L,Dekhuijzen R,Dubus JC,Magnan A,Massone F,Sanchis J,Viejo JL,Voshaar T,Aerosol Drug Management Improvement Team.

    更新日期：2006-09-01 00:00:00

  • Assessment of patient performance of the HandiHaler compared with the metered dose inhaler four weeks after instruction.

    abstract：:The HandiHaler is a novel breath-actuated dry powder system designed for the delivery of tiotropium 18microg daily in the treatment of COPD. We compared patient ability to use the HandiHaler or metered dose inhaler (MDI) device correctly 4 weeks after receiving brief instructions and device demonstration. A single-bli...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/s0954-6111(03)00162-8

    authors： Dahl R,Backer V,Ollgaard B,Gerken F,Kesten S

    更新日期：2003-10-01 00:00:00

  • Interstitial lung abnormalities are associated with increased mortality in smokers.

    abstract：OBJECTIVE:The aim of this study was to investigate whether smokers with incidental findings of interstitial lung abnormalities have an increased mortality during long-term follow-up, and review the contributing causes of death. METHODS:Baseline CT scans of 1990 participants from the Danish Lung Cancer Screening Trial ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.rmed.2018.02.001

    authors： Hoyer N,Wille MMW,Thomsen LH,Wilcke T,Dirksen A,Pedersen JH,Saghir Z,Ashraf H,Shaker SB

    更新日期：2018-03-01 00:00:00

  • Exhaled nitric oxide measurements: correction equation to compare hand-held device to stationary analyzer.

    abstract：INTRODUCTION:Exhaled nitric oxide (FE(NO)) is a reliable non-invasive marker of airway inflammation. In 2003 FE(NO) chemiluminescence analyzer (NIOX; Aerocrine AB, Solna, Sweden) was approved by U.S. Food and Drug Administration for monitoring asthma therapy. Recently, the same company developed a portable device using...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2008.04.006

    authors： Pizzimenti S,Bugiani M,Piccioni P,Heffler E,Carosso A,Guida G,Rolla G

    更新日期：2008-09-01 00:00:00

  • Use of the QuantiFERON-TB Gold test in Japanese patients with sarcoidosis.

    abstract：BACKGROUND AND OBJECTIVE:Mycobacterium tuberculosis has been proposed as a candidate agent for the cause of sarcoidosis. The QuantiFERON-TB Gold test has a higher specificity for detecting M. tuberculosis infection than the conventional tuberculin skin test. This study aimed to investigate the rate of positive QuantiFE...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.09.013

    authors： Inui N,Suda T,Chida K

    更新日期：2008-02-01 00:00:00

  • Health-related quality of life in asthma patients - A comparison of two cohorts from 2005 and 2015.

    abstract：INTRODUCTION:The aim was to investigate temporal variation in Health-Related Quality of Life (HRQL) and factors influencing low HRQL, in patients with asthma. MATERIAL AND METHODS:Questionnaire data on patient characteristics and the mini-Asthma Quality of Life Questionnaire (mini-AQLQ) scores from two separate cohort...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2017.10.010

    authors： Sundh J,Wireklint P,Hasselgren M,Montgomery S,Ställberg B,Lisspers K,Janson C

    更新日期：2017-11-01 00:00:00

  • Non-reversible airway obstruction in never smokers: results from the Austrian BOLD study.

    abstract：BACKGROUND:The presence of non-reversible airway obstruction (AO) in never smokers has only received limited attention until now. METHODS:We analyzed data from the Austrian Burden of Obstructive Lung Disease (BOLD) study. We defined non-reversible AO as post-bronchodilator FEV(1)/FVC <0.7 which corresponds to COPD I a...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2008.07.007

    authors： Lamprecht B,Schirnhofer L,Kaiser B,Buist S,Studnicka M

    更新日期：2008-12-01 00:00:00

  • Effect of single doses of inhaled lignocaine on FEV1 and bronchial reactivity in asthma.

    abstract：:Inhaled lignocaine appeared to have considerable steroid sparing properties in an uncontrolled trial in 20 patients with oral-steroid-dependent asthma. Since it can also cause bronchoconstriction, safety needs to be studied under controlled conditions. We have performed a randomized, double-blind, placebo-controlled s...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0954-6111(98)90142-1

    authors： Harrison TW,Tattersfield AE

    更新日期：1998-12-01 00:00:00

  • High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia.

    abstract：:Chemokines such as regulated on activation, normal T-cell expressed and secreted (RANTES), monocyte chemoattractant protein (MCP)-1, monocyte inflammatory protein (MIP)-lalpha have been reported to play an important role in the pathogenesis of interstitial lung diseases. Among idiopathic interstitial pneumonia (IIP), ...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2004.03.008

    authors： Yoshioka S,Mukae H,Sugiyama K,Kakugawa T,Sakamoto N,Nakayama S,Abe K,Fujii T,Kadota J,Kohno S

    更新日期：2004-10-01 00:00:00

  • Asthma and gastro-oesophageal reflux: can the response to anti-reflux therapy be predicted?

    abstract：:The aim of the study was to investigate which features predict favourable response to omeprazole therapy in asthmatics with gastro-oesophageal reflux (GER). The study population consisted of 52 outpatient asthmatics with GER who had completed an intervention where they were randomized to receive omeprazole 40 mg once ...

    journal_title：Respiratory medicine

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1053/rmed.2001.1055

    authors： Kiljander T,Salomaa ER,Hietanen E,Helenius H,Liippo K,Terho EO

    更新日期：2001-05-01 00:00:00

  • Prevalence of work-related symptoms and serum-specific antibodies to wheat flour in exposed workers in the bakery industry.

    abstract：BACKGROUND:Although baker's asthma (BA) is a common occupational asthma, there have been few reports on this disease in Korean subjects. OBJECTIVES:We evaluated the prevalence of serum-specific IgE, IgG1, and IgG4 antibodies in relation to work-related respiratory symptoms in a single industrial bakery. METHODS:Three...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/j.rmed.2007.11.015

    authors： Hur GY,Koh DH,Kim HA,Park HJ,Ye YM,Kim KS,Park HS

    更新日期：2008-04-01 00:00:00

  • Continuous positive airway pressure ventilation for respiratory failure associated with Pneumocystis carinii pneumonia.

    abstract：:The value of continuous positive airway pressure (CPAP) ventilation via a tight fitting face mask was assessed in eight HIV-1 antibody-positive patients with Pneumocystis carinii pneumonia who were in hypoxaemic respiratory failure. All patients were conscious, able to protect their airway and not hypercapnic. Treatme...

    journal_title：Respiratory medicine

    pub_type： 杂志文章

    doi：10.1016/s0954-6111(06)80291-x

    authors： Miller RF,Semple SJ

    更新日期：1991-03-01 00:00:00