Myofibroblasts and myoepithelial cells in the chicken harderian gland.

Abstract:

:An electron microscopic study of the myoepithelial cells in the chicken Harderian gland provides evidence that these cells can be transformed into myofibroblasts. After the application of a Brucella ovis suspension in sterile saline onto the eyeball, every 5 minutes for half an hour, myoepithelial cells gradually develop over a 90-minute period the characteristic features of myofibroblasts: bundles of intracytoplasmic microfilament; abundant rough endoplasmic reticulum; prominent Golgi complex; and surface membrane differentiations, that provide attachment to neighbouring epithelial cells. No typical desmosomes are observed. Besides, the intercellular space between epithelial cells and myofibroblasts increases and the basement membrane adjacent to myofibroblasts disappears. Hypoxia is hypothesized to be involved in the transformation of myoepithelial cells into myofibroblasts.

journal_name

Histol Histopathol

authors

del Cacho E,Gallego M,Felices C,Bascuas JA

subject

Has Abstract

pub_date

1991-07-01 00:00:00

pages

303-8

issue

3

eissn

0213-3911

issn

1699-5848

journal_volume

6

pub_type

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