Abstract:
:To determine the appropriate time for bone reconstruction after irradiation, the healing process after autogenous iliac bone transplantation in the irradiated parietal bone was examined by scanning electron microscopy and light microscopy. Bone transplantation was carried out at the second and the fourth weeks after Cobalt-sixty (60Co) irradiation with calculated dose and fractionation. Animals without irradiation were used as control. The results show the appearance of mesenchymal cells and blood vessels around the transplantation to be extremely few one week after transplantation which was carried out at the second week after irradiation. These inhibitions were still seen two weeks after transplantation. Four weeks after transplantation, there were no differences in the bone formation among the experimental groups. Bone formation in the transplantation at the fourth week after irradiation was similar to that of the control group. Microvascularization in the transplantation at the second week after irradiation was inhibited one week after transplantation. The delay in bone healing was responsible for the retardation of revascularization and caused microcirculatory failures as well as the damage of osteogenic cells. It is quite clear that damaged cells and tissues recovered by the elapse of time under the irradiation procedure employed in this study and also that bone formation was carried out in the physiological process. We think that bone transplantation after irradiation should be done after recovery from the radiation damage to the periosteal cells and the blood vessels.
journal_name
Histol Histopatholjournal_title
Histology and histopathologyauthors
Takekawa M,Matsuda M,Ohotubo Sdoi
10.14670/HH-15.7subject
Has Abstractpub_date
2000-01-01 00:00:00pages
7-19issue
1eissn
0213-3911issn
1699-5848journal_volume
15pub_type
杂志文章abstract::The anti-oxidant food additive, butylated hydroxytoluene (BHT), was fed to Sprague-Dawley rats at three concentrations: 0.2%, 0.4% and 0.8% for periods of 6, 12, 18 and 24 weeks, and the results were compared with corresponding groups treated with a potent carcinogen, 7,12-dimethylbenz[a]anthracene (DMBA) groups, with...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-14.391
更新日期:1999-04-01 00:00:00
abstract::Differentiating nonspecific interstitial pneumonia (NSIP) from usual interstitial pneumonia (UIP) is important for the determination of both treatment and prognosis. Using two-dimensional fluorescence difference gel electrophoresis (2D-DIGE), we examined 8 UIPs, 8 NSIPs, and 30 normal lung tissues. Comparisons with co...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-29.377
更新日期:2014-03-01 00:00:00
abstract::Autophagy and apoptosis are two important molecular mechanisms that maintain cellular homeostasis under stress conditions. Autophagy represents an intracellular mechanism responsible for turnover of organelles and long-lived proteins through a lysosome-dependent degradation pathway. Cell death signals or sustained str...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-11-714
更新日期:2016-05-01 00:00:00
abstract::Hexachlorobenzene (HCB) is a fungicide and a pollutant of increasing concern in industrialized regions of the world. Reproductive failure is one of the effects of HCB upon mammals. Alteration of cell shape in the ovary surface epithelium (OSE) of Cynomolgus monkeys following oral administration of HCB was observed in ...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::The reactivity of endothelial cells to putative endothelial cell-specific markers varies with species, with vessel size and with the organ studied. To determine their value in studies of fetal rat lung, and whether organ immaturity would also influence reactivity, we studied endothelial cell immunoreactivity to antibo...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::In view of the limitations of conventional prognostic factors such as differentiation degree, metastatic lymph nodes, hormonal receptors and others, especially when early lesions are found, additional new markers have been studied, such as gene amplification and cell proliferation index, in order to choose the appropr...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract::The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondr...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1988-07-01 00:00:00
abstract::Histochemical distribution of glycoproteins, carbohydrates and proteins rich in different amino acids were studied using histological and histochemical procedures, in Senegal sole, Solea senegalensis (Kaup, 1858) larvae from hatching until day 15. Glycogen, proteins and glycoproteins were detected in the yolk-sac of t...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Serotonin-producing pancreatic endocrine tumours are rare neoplasms which in most cases exhibit malignant biological behaviour. These tumours, in the majority of the well-documented cases, are composed of argyrophil- and argentaffin-positive cells which contain large pleomorphic neurosecretory granules. In contrast, a...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::The hindgut is the major site in the horse for nutrient digestion and absorption. Most of this activity occurs in the large intestinal compartments, i.e., cecum, right and left ventral colon and left and right dorsal colon. The colonic pelvic flexure is a short and narrow loop connecting the left ventral and left dors...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-15.983
更新日期:2000-07-01 00:00:00
abstract::Fatty acid binding proteins (FABPs) are 15-kDa proteins responsible for the transport of fatty acids both intracellularly and extracellularly. Consisting of 12 different isoforms, some of the proteins have been found to be released in the serum and to be correlated with various diseases including cancer. Differential ...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-18-014
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Honey and olive oil are natural products that have high nutritional values, and therapeutic properties. Cytotoxic drugs, like methotrexate (MTX) are used to treat malignancies in tumour cells; however, these drugs also have serious side effects that could threaten the patient's life. AIM:To evaluate the pot...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-18-126
更新日期:2019-12-01 00:00:00
abstract::The purpose of our study was to elucidate pathways of genetically programmed cell death (apoptosis) in corneas with macular dystrophy. 10 corneal buttons (10 patients) with macular dystrophy and 8 buttons (8 patients) from enucleated eyes with chorioideal melanoma (controls) were analysed histologically. Immunohistoch...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-25.287
更新日期:2010-03-01 00:00:00
abstract::The population of the world grows every year, and life expectancy tends to increase. Thus, long-term preservation of teeth in aged individuals is an urgent issue. The main causes of tooth loss are well known to be periodontitis, caries, fractures, and orthodontic conditions. Although implant placement is a widely acce...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-29.1249
更新日期:2014-10-01 00:00:00
abstract::The distribution of peptidergic nerves in canine mammary tissues was studied by immunohistochemical techniques. In addition, the general and the noradrenergic innervations were demonstrated using protein gene product 9.5 and tyrosine hydroxylase immunoreactivities as markers, respectively. Tissue specimens from the ca...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-22.1175
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Expression of hypoxia-related tissue factors in 1p-aberrant oligodendroglial neoplasms diminishes patient outcome. Differentiated embryo-chondrocyte expressed gene 1 (DEC1) has been described as novel hypoxia-related tissue factor. In our study, we assessed the expression of DEC1 in 1p aberrant oligodendrogl...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-20.1173
更新日期:2005-10-01 00:00:00
abstract::The effects of diethylstilbestrol (DES) and of long-acting somatostatin analog, octreotide (SMS) on the rat anterior pituitary microvasculature have been studied by means of computer-assisted image analysis. Additionally, the effects of DES and SMS on prolactin secretion and anterior pituitary cell proliferation have ...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::We have studied the occurrence and specific features of liver cell dysplasia (LCD) in Chinese patients showing liver cirrhosis with or without hepatocellular carcinoma (HCC). Three types of LCD (SLCD, LLCDo, LLCDe) were morphologically defined, and these types were further analyzed using karyometry, estimation of nucl...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Recently, the characterization of mucinous tubular and spindle-cell carcinoma (MTSCC) has been established. MTSCC predominantly occurs in females. This tumor is histologically characterized by eosinophilic cytoplasm, elongated and anastomosing tubules, myxomatous stroma and low-grade nuclear cytology. Proliferation of...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-20.221
更新日期:2005-01-01 00:00:00
abstract::A current concern about the biological effects of electromagnetic fields (EMF) is increasing with the wide spread use of X-band microwaves (MW, 8-10 GHz range). Gigahertz transverse electromagnetic (GTEM) field flat transmission lines are currently being used for experimental exposure of biological samples to high fre...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-26.1187
更新日期:2011-09-01 00:00:00
abstract::The techniques for light and electron microscopic radioautography developed in our laboratory are described. The outlines of the applications to various tissues and organs are also briefly summarized. First, the techniques are explained in detail. These techniques can be divided into two categories, i.e., chemical fix...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:
更新日期:1997-10-01 00:00:00
abstract::Sixty male Wistar rats were used for this experiment and assigned at random to the control group or to the stimulation method. Control rats show cerebral asymmetry with right bias at the frontal and occipital lobes. In the case of stimulated rats the differences from the occipital zone increase while those from the fr...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract::The aim of our study was to document whether relationships existed among bone morphogenetic proteins (BMPs), peripheral nerve and neoplastic lesions of nerve sheath tumors. The mRNA transcriptions of BMP-2, 3, 4 and 5 in 10 cases of schwannoma, three cases of malignant schwannoma and two cases of trigeminal neuralgia ...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-16.1013
更新日期:2001-10-01 00:00:00
abstract::One hundred and eleven pituitary glands of patients (93 males, 18 females; mean age 32 years, 5 months) who died of fully developed AIDS or ARC were examined under light microscopy with the aid of immunohistochemistry. On post mortem (p.m.) examination a wide series of multiorgan alterations was noticed. Microscopical...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Nitric oxide (NO) is a biological messenger molecule produced by one of the essential amino acids L-arginine by the catalytic action of the enzyme NO synthase (NOS). The dual role of NO as a protective or toxic molecule is due to several factors, such as; the isoform of NOS involved, concentration of NO and the type o...
journal_title:Histology and histopathology
pub_type: 杂志文章,评审
doi:10.14670/HH-21.445
更新日期:2006-04-01 00:00:00
abstract::The ultrastructure of pinealocytes was studied in rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors which were subjected to experimental manipulations known as enhancers of pineal actions (anosmia, underfeeding or cold exposure). In these animals we found: (I)--more nuclei with deep nuclear invaginations...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
abstract::We examined morphological characteristics of the carotid body of spontaneously hypertensive rats (SHR), those of age-matched normotensive Wistar rats (NWR), and age-matched genetically comparable Wistar Kyoto rats (WKY). We examined the distribution and abundance of four different regulatory neuropeptides: substance P...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-26.369
更新日期:2011-03-01 00:00:00
abstract::Cyclin A, cyclin E, BUBR1, MAD2 and Aurora A are all cell-cycle regulatory proteins and have been proven to play crucial roles in carcinogenesis. However, their expression patterns in invasive ductal breast carcinoma (IDBC) are controversial and unclear. In this study, we examined the expression status of these candid...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-26.761
更新日期:2011-06-01 00:00:00
abstract::Glomerular alterations of experimental diabetes mellitus are observed in animals submitted to a reduction in renal mass, suggesting that some mechanisms responsible for the progression of renal disease are common. The aim of this study was to investigate the effect of nephrectomy on the renal function and morphology o...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:10.14670/HH-19.1085
更新日期:2004-10-01 00:00:00
abstract::A study was undertaken to analyze the spatio-temporal pattern of mesenchymal cell proliferation in the developing palate of quail. Quail embryos were grown in shell-less culture. The developing palates were labelled with 3H-thymidine between culture days 2-6 (which corresponded in vivo incubation days 5-9), and proces...
journal_title:Histology and histopathology
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00