Abstract:
PURPOSE:Previous neuroimaging studies of oddball tasks and other paradigms measuring attention processes support right hemisphere dominance for attentional processes. Using an auditory selective attention task, we studied the functional asymmetry of the human brain in response to attended or unattended deviant tones. Secondly, we examined whether a congruency or a discrepancy between audio-spatial and visuo-spatial cued attentional resources may influence the activity elicited by an auditory selective attention task. METHODS:We used event-related functional magnetic resonance imaging (fMRI) to study healthy adults as they performed an auditory oddball task in which a spatial-cued instruction indicated the ear to attend a monaural deviant tone. We addressed the question of congruency/discrepancy between attentional resources by using three different eye positions during the performance of the auditory oddball task. RESULTS:Relative to standard tones, both attended and unattended deviant tones (DTs) presented to either ear elicit the activation of a widespread bilaterally distributed cortical and subcortical network. A subset of this network, essentially frontal and temporal areas, showed not only greater right than left activity but an enhancement of this rightward asymmetry in response to attended DTs. The only cortical region that showed a leftward asymmetry in response to attended DTs overlapped Heschl gyrus and planum temporale, unmasking a left hemisphere preference of both primary and secondary auditory cortex for processing simple attended monaural stimuli. Questioning the impact of eye position during auditory oddball task, we observed a lesser activity in right integrative crossmodal areas (superior temporal sulcus, opercular part of the inferior frontal gyrus, pre-SMA) when the eye positions were contralateral to detected DTs. These regions may be tuned to best respond when both visuo-spatial and audio-spatial attentional resources work together. CONCLUSION:These results support the assumption that the right hemisphere is preferentially engaged in processing audio-spatial attentional resources and underline the interest to study the crossmodal integration of attentional resources by the mean of the detection of DTs in different eye positions.
journal_name
Restor Neurol Neuroscijournal_title
Restorative neurology and neuroscienceauthors
Petit L,Simon G,Joliot M,Andersson F,Bertin T,Zago L,Mellet E,Tzourio-Mazoyer Nsubject
Has Abstractpub_date
2007-01-01 00:00:00pages
211-25issue
3-4eissn
0922-6028issn
1878-3627journal_volume
25pub_type
杂志文章abstract::To examine the regeneration capacity of dorsal septohippocampal neurons in the presence of an artificial growth-promoting substrate, biocompatible polymeric hydrogels were implanted between the septum and the hippocampus in a fimbria-fornix lesion cavity. Unmodified (control) or aminosugar-containing (glucosamines or ...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:In low vision patients, the assessment of contrast sensitivity is an essential tool to determine the stage of visual impairment. However, traditional contrast sensitivity tests rely on verbal feedback, and the expertise of the examiner. OBJECTIVE:In the current study, a fast, OKN-based virtual diagnosis too...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-190937
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abstract:BACKGROUND:Multiple Sclerosis is a heterogeneous disorders involving in early stage gait and balance. Together with immunomodulating therapies, rehabilitation had a crucial role in improving motor tasks and quality of life. Between the emerging techniques, Focal Vibrations (FV) could play a role, but they have been use...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.3233/RNN-160665
更新日期:2016-09-21 00:00:00
abstract:PURPOSE:Immunomodulatory agents are often combined in organ transplantation to minimize toxicity and enhance therapeutic effect. We hypothesized that combining low-dose FK506 with anti-CD40 Ligand (anti-CD40L mAb) would enhance regeneration through peripheral nerve allografts while preserving immune unresponsiveness. ...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:2005-01-01 00:00:00
abstract::Corticomotor excitability is reduced during rhythmic passive movement compared to rest, but it is not known whether the mechanism is purely segmental or includes a supraspinal pathway. To determine how interruption of sensory projections at a supraspinal level affects corticomotor excitability during passive movement,...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::The mechanisms underlying recovery of function following damage to the CNS, although suspected, are virtually unknown. After damage to the adult cat spinal cord, recovery of motor behavior depends on which systems have been interrupted and which remain intact. For example, following hemisection, overground (voluntary)...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1991-245623
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Focal dystonia in musicians (MD) is a task-specific movement disorder with a loss of voluntary motor control during instrumental playing. Defective inhibition on different levels of the central nervous system is involved in the pathophysiology. Sensorimotor retraining is a therapeutic approach to MD and aims...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章,随机对照试验
doi:10.3233/RNN-2011-0582
更新日期:2011-01-01 00:00:00
abstract::Axonotmesis of the left sciatic nerve was performed on adult male Wistar rats. T1 values of the crushed nerve samples were determined with proton magnetic resonance spectroscopy. Denervation changes of the dependent hind plantar flexor muscles were assessed with proton magnetic resonance imaging of their cross-section...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1992-4601
更新日期:1992-01-01 00:00:00
abstract:INTRODUCTION:Traumatic brain injuries (TBI) are one of the most common consequences of traffic accidents. Patients with mild, moderate or severe brain injuries suffer from physical, cognitive, behavioral, emotional and social problems. Most of these problems have been a long standing focus amongst practitioners and res...
journal_title:Restorative neurology and neuroscience
pub_type: 共识发展会议,杂志文章,评审
doi:
更新日期:2002-01-01 00:00:00
abstract::Bridging large defects in mixed nerves is still an unsolved problem in reconstructive microsurgery. Two main aspects may be distinguished: one is to obtain an appropriate substitute for the lost neural tissue, the second to direct fibers toward their previous end-organs with the highest possible specificity. In the pr...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1997-11306
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:To evaluate whether repetitive optokinetic stimulation with active pursuit eye movements leads to substantial and greater recovery from visual neglect as compared to conventional visual scanning training. METHODS:Two groups of five patients with leftsided hemineglect were consecutively collected and matched fo...
journal_title:Restorative neurology and neuroscience
pub_type: 临床试验,杂志文章
doi:
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:The aim of the study was to examine if improvements of stimulus detection performance in visual field tests after intensive visual training of the visual field border zone in patients with visual field defects are associated with changes in self-reported vision- and health-related quality of life (QoL). METHOD...
journal_title:Restorative neurology and neuroscience
pub_type: 临床试验,杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:Several studies have shown that transcranial direct current stimulation (tDCS) is a useful tool to enhance language recovery in aphasia. It has also been suggested that modulation of the neurotrophin brain-derived neurotrophic factor (BDNF) might be part of the mechanisms involved in tDCS effects on synaptic co...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-130323
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Patients suffering from chronic disorders of consciousness (DOC), including minimally conscious state (MCS) and unresponsive wakefulness syndrome (UWS), typically show an awareness impairment paralleled by a significant reflex hyper-excitability, which depend on the cortical deafferentation following brain-d...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-160655
更新日期:2017-01-01 00:00:00
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journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-180828
更新日期:2019-01-01 00:00:00
abstract:PURPOSE:The illusory ownership of a fake hand as part the body follows synchronous tactile stimulation over a visible rubber hand and a covered hand. Whether brain plasticity mechanisms after sensory and motor disconnection modulates this illusion remain unexplored. METHODS:We tested a tetraplegic man after synchronou...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-130385
更新日期:2014-01-01 00:00:00
abstract::The application of brain stimulation techniques for modulation of cortical excitability changes underlying spatial neglect following right-brain-damage has been the first application of brain stimulation in the rehabilitation setting. Several factors concur in making neglect a prototype of cognitive disorders that can...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章,评审
doi:10.3233/RNN-2011-0613
更新日期:2011-01-01 00:00:00
abstract::In rat sciatic nerves, IGF-I or bFGF was applied distal to a crush to evaluate their effects upon the restoration of the neuromuscular function. In comparison with the recovery following a simple crush, treatment with growth factors resulted in (i) enhanced elongation of regenerating axons ( + 24%) up to day 3 post le...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1993-5302
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Traumatic brain injury (TBI) -induced brain edema can be reduced by acute progesterone (PROG) treatment in young adult males and females, and in aged males. To extend these findings we tested these hypotheses: 1. Acute PROG treatment post-TBI will reduce cortical edema in aged females as much as in young adults...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-2009-0475
更新日期:2009-01-01 00:00:00
abstract::We are interested in the role cyclic AMP may play as a mediator of growth factor-induced gene expression in regenerating peripheral nerves. As a first step, we investigated mRNA levels and protein synthesis in intact frog dorsal root ganglia (DRG) treated with the adenylate cyclase activator, forskolin in vitro. Forsk...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1990-13408
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journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-1991-245603
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journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-150591
更新日期:2016-01-01 00:00:00
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journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:We wished to evaluate the efficacy of vision restoration therapy (VRT) in patients with post-chiasmatic brain damage using different functional perimetric tests. These were compared with measures of subjective vision and reaction time. METHODS:An open trial was conducted with hemianopia/scotoma (n=16) patients...
journal_title:Restorative neurology and neuroscience
pub_type: 临床试验,杂志文章
doi:
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Low-frequency rTMS can induce upregulation of excitability in the contralateral hemisphere by interhemispheric interaction. OBJECTIVE:The aim of this study was to compare the effects of interhemispheric modulation on hemodynamic changes after applying low-frequency rTMS over the anatomical hand knob (HK) an...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-201032
更新日期:2020-01-01 00:00:00
abstract::Traumatic brain and spinal cord injuries are severe burdens for the patients, their relatives, the health care providers and society as a whole. Recent data demonstrate the magnitude of the problem: It is mostly a disease of the young gen-eration (age 20-45 years) with mortality rates for severe traumatic brain injury...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::The olfactory nerve differs from cranial nerves III-XII in that it contains a specialised type of glial cell, called 'olfactory ensheathing cell' (OEC), rather than Schwann cells. In addition, functional neurogenesis persists postnatally in the olfactory system, i.e. the primary olfactory pathway continuously rebuilds...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章,评审
doi:
更新日期:2008-01-01 00:00:00
abstract::A long-term goal in motor rehabilitation is that treatment is not selected on the basis of 'schools of thought', but rather, based on knowledge about efficacy and effectiveness of specific interventions for specific situations (e.g. functional syndromes). Motor dysfunction after stroke or TBI can be caused by many dif...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:Despite advances towards potential clinically viable therapies there has been only limited success in improving functional recovery following traumatic brain injury (TBI). In rats, exposure to an enriched environment (EE) improves learning and fosters motor skill development. Induced pluripotent stem cells (iPS...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:10.3233/RNN-140408
更新日期:2014-01-01 00:00:00
abstract::Purpose: Damage of primary visual cortex in adult humans, monkeys and cats severely disrupts vision by disconnecting much of the cogni-tive processing machinery of extrastriate cortex from its source of visual signals in the retina. Equivalent lesions sustained early in life result in partial sparing of visual process...
journal_title:Restorative neurology and neuroscience
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00