Marine amphiphilic siderophores: marinobactin structure, uptake, and microbial partitioning.

Abstract:

:Marinobactins A-E are a suite of amphiphilic siderophores which have a common peptidic head group that coordinates Fe(III), and a fatty acid which varies in length and saturation. As a result of the amphiphilic properties of these siderophores it is difficult to study siderophore-mediated uptake of iron, because the amphiphilic siderophores partition indiscriminately in microbial and other membranes. An alternative method to distinguish amphiphilic siderophore partitioning versus siderophore-mediated active uptake for Fe(III)-marinobactin E has been developed. In addition, a new member of the marinobactin family of siderophores is also reported, marinobactin F, which has a C(18) fatty acid with one double bond and which is substantially more hydrophobic that marinobactins A-E.

journal_name

J Inorg Biochem

authors

Martinez JS,Butler A

doi

10.1016/j.jinorgbio.2007.07.007

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

1692-8

issue

11-12

eissn

0162-0134

issn

1873-3344

pii

S0162-0134(07)00181-X

journal_volume

101

pub_type

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