Abstract:
:The interaction of vanadate with 5'-mononucleotides, ADP, ATP, and various molecules containing some of their chemical moieties was studied in aqueous solution in the pH region of 5-9 using proton, 13C, 31P, and 51V nuclear magnetic resonance (NMR) spectroscopy. All the compounds studied formed noncyclic vanadate esters through interaction of monovanadate or divanadate with the hydroxyl groups of the ribose ring. Noncyclic anhydrides were also formed with the phosphate groups of ribose 5-phosphate, the mononucleotides, ADP, ATP, phosphate, pyrophosphate, and tripolyphosphate. In particular, ADP and ATP analogs resulted from AMP (AMPV and AMPV2) and from ADP (ADPV). Cyclic esters of trigonal bipyramidal geometry resulted from the interaction of vanadate with two ribose ring cis hydroxyl groups. AMP, CMP, and UMP formed two such complexes of 1:1 and 1:2 stoichiometries, similar to what has been observed for uridine and other nucleosides. However, 2'-deoxy-AMP does not yield this type of complexes. ADP and ATP also form similar cyclic ester complexes with vanadate, which does not chelate their pyrophosphate and tripolyphosphate moieties. Nevertheless, the separate pyrophosphate (PP) and tripolyphosphate (PPP) ligands form cyclic anhydrides of octahedral geometry with vanadate. However, their binding to vanadate is weaker than that of the ribose ring of nucleotides. Competition experiments between ethylene glycol and phosphate (P), pyrophosphate (PP), or tripolyphosphate (PPP) show that the relative strength of the interaction of these ligands with vanadate is PP greater than ethylene glycol greater than PPP greater than P.
journal_name
J Inorg Biochemjournal_title
Journal of inorganic biochemistryauthors
Geraldes CF,Castro MMdoi
10.1016/0162-0134(89)80044-3subject
Has Abstractpub_date
1989-11-01 00:00:00pages
213-32issue
3eissn
0162-0134issn
1873-3344pii
0162-0134(89)80044-3journal_volume
37pub_type
杂志文章abstract::[Au(dppz)(2)]Cl(3) was synthesized by the reaction of HAuCl(4) in excess of the dypirido[3,2-a: 2,3-c]phenazine (dppz) ligand. This complex was characterized by elemental analysis, fast atom bombardment (FAB) mass, NMR, UV-visible and IR spectroscopies. DNA-gold complex interactions were studied by spectroscopic titra...
journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章,评审
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更新日期:1992-08-15 00:00:00
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更新日期:2008-12-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:1987-11-01 00:00:00
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journal_title:Journal of inorganic biochemistry
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更新日期:2017-12-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/s0162-0134(99)00175-0
更新日期:2000-04-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/0162-0134(93)80015-2
更新日期:1993-05-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of inorganic biochemistry
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更新日期:2013-05-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/s0162-0134(97)10025-3
更新日期:1998-02-01 00:00:00
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journal_title:Journal of inorganic biochemistry
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doi:10.1016/0162-0134(86)80095-2
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doi:10.1016/j.jinorgbio.2013.09.008
更新日期:2013-12-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章,评审
doi:10.1016/j.jinorgbio.2007.10.021
更新日期:2008-03-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/0162-0134(94)80011-1
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更新日期:1994-02-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:1987-07-01 00:00:00
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:2000-07-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:2004-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/0162-0134(91)84004-s
更新日期:1991-05-15 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2003.09.012
更新日期:2004-01-01 00:00:00
abstract::The CuA center is a dinuclear Cu2S2(Cys) electron transfer center found in cytochrome c oxidase and nitrous oxide reductase. In a previous investigation of the equatorial histidine ligands' effect on the reduction potential, electron transfer and spectroscopic properties of the CuA center, His120 in the engineered CuA...
journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/s0162-0134(99)00214-7
更新日期:2000-01-15 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2013.03.014
更新日期:2013-07-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2016.02.002
更新日期:2016-06-01 00:00:00
abstract::The interaction of phytic acid with Ca(II) has been studied by potentiometric titration and by measurement of free Ca(II) concentrations using an ion Selective electrode. With increasing Ca(II) concentration, the titration curve of phytic acid is displaced to regions of lower pH. In the binding of calcium ions to phyt...
journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/0162-0134(86)80105-2
更新日期:1986-05-01 00:00:00