Preparation, characterization, and antitumor activity of new ethylenediamine platinum(IV) complexes containing mixed carboxylate ligands.

abstract：:Several metal ions and their complexes have been known to mimic the action of insulin in in vitro and in vivo systems. We prepared a family of Zn(II) complexes derived from amino ligands with Zn(Nn) (n=3 and 4) coordination modes, the insulinomimetic activity being estimated by an inhibitory effect of free fatty acid ...

journal_title：Journal of inorganic biochemistry

authors： Yoshikawa Y,Kondo M,Sakurai H,Kojima Y

更新日期：2005-07-01 00:00:00

abstract：:The visible and ultraviolet circular dichroic spectra resulting from the interaction of bovine alpha-lactalbumin with successive Cu(II) ions have been recorded under a variety of conditions. Analysis of the observed change-transfer and d-d band transitions can be made in terms of two kinds of binding sites: at a histi...

journal_title：Journal of inorganic biochemistry

authors： Tieghem E,Van Dael H,Van Cauwelaert F

更新日期：1991-05-01 00:00:00

abstract：:The heme of neuronal nitric oxide synthase (nNOS) participates in O2 activation but also binds self-generated NO, resulting in reversible feedback inhibition. We utilized mutagenesis to investigate if a conserved tryptophan residue (Trp409), which engages in pi-stacking with the heme and hydrogen bonds to its axial cy...

journal_title：Journal of inorganic biochemistry

authors： Adak S,Stuehr DJ

更新日期：2001-02-01 00:00:00

abstract：:The resonance Raman spectra of native stellacyanin and its Ni(II) derivative has been investigated. Raman intensity as a function of the exciting frequency shows minima at about 440--460 nm. Moreover, the resonance Raman spectra of the Ni(II) derivative indicate similar symmetry and nature of ligands, namely, one cyst...

journal_title：Journal of inorganic biochemistry

authors： Musci G,Desideri A,Morpurgo L,Tosi L

更新日期：1985-02-01 00:00:00

abstract：:Prion diseases are neurodegenerative disorders associated with a conformational change of the normal cellular isoform of the prion protein (PrP(C)) to an abnormal scrapie isoform (PrP(Sc)). human prion protein (hPrP(C)) is able to bind up to six Cu(II) ions. Four of them are distributed in the octarepeat domain, conta...

journal_title：Journal of inorganic biochemistry

authors： Valensin D,Padula EM,Hecel A,Luczkowski M,Kozlowski H

更新日期：2016-02-01 00:00:00

abstract：:Three binuclear Ru(II) complexes with two [Ru(bpy)(2)(pip)](2+)-based subunits {where bpy=2,2'-bipyridine and pip=2-phenylimidazo[4,5-f][1,10]phenanthroline} being linked by varied lengths of flexible bridges, were synthesized and characterized by (1)H NMR, elemental analysis, UV-visible (UV-vis) and photoluminescence...

journal_title：Journal of inorganic biochemistry

authors： Ju CC,Zhang AG,Yuan CL,Zhao XL,Wang KZ

更新日期：2011-03-01 00:00:00

abstract：:The hypothesis that the recent rapid evolution of primate cytochromes c, which primarily involves residues in the least stable Ω-loop (Ω-loop C, residues 40-57), stabilizes the heme crevice of cytochrome c relative to other mammals, is tested. To accomplish this goal, we have compared the properties of human and spide...

journal_title：Journal of inorganic biochemistry

authors： Goldes ME,Jeakins-Cooley ME,McClelland LJ,Mou TC,Bowler BE

更新日期：2016-05-01 00:00:00

abstract：:Herein we present the synthesis, structural and spectroscopic characterization of coordination compounds of cobalt(II), copper(II) and zinc(II) with 2-methylbenzimidazole (2mbz), 2-phenylbenzimidazole (2phbz), 2-chlorobenzimidazole (2cbz), 2-benzimidazolecarbamate (2cmbz) and 2-guanidinobenzimidazole (2gbz). Their cyt...

journal_title：Journal of inorganic biochemistry

authors： Sánchez-Guadarrama O,López-Sandoval H,Sánchez-Bartéz F,Gracia-Mora I,Höpfl H,Barba-Behrens N

更新日期：2009-09-01 00:00:00

abstract：:Nanosized flower-like ZnO was synthesized by a simple hydrothermal method which is a convenient, environment friendly, inexpensive and efficient process. Raman spectroscopy, X-ray diffraction (XRD) and scanning electron microscope (SEM) were used to confirm the material structure and the crystallite microstructure. Th...

journal_title：Journal of inorganic biochemistry

authors： Liu YL,Yang YH,Yang HF,Liu ZM,Shen GL,Yu RQ

更新日期：2005-10-01 00:00:00

abstract：:The relationship between respiratory and neurological effects of exposure to aluminium (Al) was investigated in a group of foundry workers exposed to Al at concentrations below the threshold limit value (TLV) binding in Poland (2.0 mg Al2O3 m(-3)). Neurological and neurophysiological parameters indicated subclinical e...

journal_title：Journal of inorganic biochemistry

authors： Halatek T,Sinczuk-Walczak H,Rydzynski K

更新日期：2005-09-01 00:00:00

abstract：:One-electron reduction and oxidation induced by vanadium complexes are demonstrated to be useful in oxidative and reductive transformations of carbonyl compounds. The redox interaction between vanadium complexes and redox-active ligands is achieved with coenzyme PQQ and polyanilines that afford the corresponding redox...

journal_title：Journal of inorganic biochemistry

authors： Hirao T

更新日期：2000-05-30 00:00:00

abstract：SYNOPSIS:MnII complexes formed with cis- and trans-DO2A (DO2A=1,4,7,10-tetraazacyclododecane-1,4 (or 1,7) -diacetic acid) chelators were investigated by pH-potentiometry, 1H relaxometry, UV-vis spectrophotometry and cyclic voltammetry. The physico-chemical characteristics of MnII complexes of these structure isomers do...

journal_title：Journal of inorganic biochemistry

authors： Garda Z,Forgács A,Do QN,Kálmán FK,Timári S,Baranyai Z,Tei L,Tóth I,Kovács Z,Tircsó G

更新日期：2016-10-01 00:00:00

abstract：:Previous work demonstrated two stimulatory effects of methyl mercury on nucleic acid synthesis: (1) in isolated nuclei, methyl mercury stimulates RNA synthesis which is catalyzed by RNA polymerase II [Frenkel and Randles, J. Biol. Chem. 257, 6275-6279 (1982)]. (2) Brief exposure of purified DNA to methyl mercury incre...

journal_title：Journal of inorganic biochemistry

authors： Frenkel GD,Ducote J

更新日期：1987-10-01 00:00:00

abstract：:The importance of electrostatic interactions between buried charges in determining the properties of membrane proteins is considered. It is demonstrated that in some cases altered properties may result from the extraction of a membrane protein into an aqueous medium even when the protein conformation is unperturbed. ...

journal_title：Journal of inorganic biochemistry

authors： Moore GR,Rogers NK

更新日期：1985-03-01 00:00:00

abstract：:Free and nanosized starch and lipid encapsulated Na5[PMo10V2O40]·nH2O complexes (abbreviated as PMoV, SEP and LEP, respectively) have been prepared and structurally characterized by Fourier transform infrared (FT-IR) spectroscopy, inductively coupled plasma (ICP) analysis, scanning electron microscopy (SEM) and transm...

journal_title：Journal of inorganic biochemistry

authors： Dianat S,Bordbar AK,Tangestaninejad S,Yadollahi B,Amiri R,Zarkesh-Esfahani SH,Habibi P

更新日期：2015-11-01 00:00:00

abstract：:Vanadium compounds have arisen as potential therapeutic agent for the treatment of cancers over the past decades. A few studies suggested that vanadyl complexes may discriminate between the cancerous and the normal cells. Here, we reported the investigation on the pro-apoptotic effect and the underlying mechanism of b...

journal_title：Journal of inorganic biochemistry

authors： Zhang Y,Wang L,Zeng K,Wang K,Yang X

更新日期：2018-11-01 00:00:00

abstract：:A laccase from the fungus Trametes villosa (TviL) was investigated in order to elucidate the reaction mechanism of the reduction of dioxygen to water performed by this blue multi-copper oxidase. The ability of TviL to activate dioxygen was studied by stopped-flow experiments and under steady-state conditions. In the s...

journal_title：Journal of inorganic biochemistry

authors： Bukh C,Lund M,Bjerrum MJ

更新日期：2006-09-01 00:00:00

abstract：:To identify regulatory elements in the rat selenoprotein W (SeW) promoter, 2090, 1265, 741, and 404 base pair truncations of genomic DNA lying immediately upstream of the SeW coding sequence were cloned into a luciferase reporter vector (pGL3-Basic from Promega, Madison, WI, USA). 3656 and 406 base pair mouse SeW prom...

journal_title：Journal of inorganic biochemistry

authors： Hooven LA,Vorachek WR,Bauman AB,Butler JA,Ream LW,Whanger PD

更新日期：2005-10-01 00:00:00

abstract：:The acsABCDE genes in the Clostridium thermoaceticum genome are used for autotrophic acetyl-CoA synthesis using the Wood-Ljungdahl pathway. A 2.8-kb region between acsC and acsD was cloned and sequenced. Two open reading frames, orf7 (approximately 1.9 kb) and acsF (approximately 0.7 kb) were identified. orf7 appears ...

journal_title：Journal of inorganic biochemistry

authors： Loke HK,Lindahl PA

更新日期：2003-01-01 00:00:00

abstract：:The interaction between cadmium and yeast hexokinase was studied. Cadmium produces changes in the aggregation state of the protein and large structures with a large molecular mass were formed. This phenomenon occurs without large modifications to the secondary structure. During this change the enzyme maintains a high ...

journal_title：Journal of inorganic biochemistry

authors： Olmo R,Blanco MD,Teijón C,Miguel del Socorro J,Teijón JM

更新日期：2002-04-10 00:00:00

abstract：:The conformation of poly[d(T-G).d(C-A)] in aqueous solution (0.1 M NaClO4, 5 mM cacodylic acid buffer, pH 6.9) was studied by circular dichroism (CD) spectroscopy in the ultraviolet. The conformation of the polynucleotide, as reflected by its chiroptical signature, changes in a highly cooperative fashion in the presen...

journal_title：Journal of inorganic biochemistry

authors： Gruenwedel DW,Cruikshank MK

更新日期：1991-07-01 00:00:00

abstract：:The antioxidant activity of flavonoids may involve their ability to complex body iron in non-redox-active forms. In this study, it was found that the catechol flavonoids rutin and quercetin are able to suppress redox-active labile plasma iron (LPI) in both buffered solution and in iron-overloaded sera. Both flavonoids...

journal_title：Journal of inorganic biochemistry

authors： Baccan MM,Chiarelli-Neto O,Pereira RM,Espósito BP

更新日期：2012-02-01 00:00:00

abstract：:A kinetic study of CO(2) hydration was carried out using the water-soluble zinc model complex with water-soluble nitrilotris(2-benzimidazolylmethyl-6-sulfonate) L1S, [L1SZn(OH(2))](-), mimicking the active site of carbonic anhydrase, in the presence and absence of anion inhibitors NCS(-) and Cl(-). The obtained rate c...

journal_title：Journal of inorganic biochemistry

authors： Nakata K,Shimomura N,Shiina N,Izumi M,Ichikawa K,Shiro M

更新日期：2002-04-28 00:00:00

abstract：:The results are reported of a potentiometric and spectrophotometric study of the proton and copper(II) complexes of methionine enkephalin and four related pentapeptides which all show greater biological activity than their parent enkephalin. Measurements were carried out at 25 degrees C and I = 0.10 mol dm-3 (KNO3). A...

journal_title：Journal of inorganic biochemistry

authors： Formicka-Kozlowska G,Pettit LD,Steel I,Livera CE,Kupryszewski G,Rolka K

更新日期：1985-08-01 00:00:00

abstract：:Horse spleen ferritin (HoSF) reconstituted with small iron cores ranging in size from 8 to 500 iron atoms was studied by magnetic susceptibility and pH measurements to determine when the added Fe3+ begins to aggregate and form antiferromagnetically coupled clusters and also to determine the hydrolytic state of the iro...

journal_title：Journal of inorganic biochemistry

authors： Hilty S,Webb B,Frankel RB,Watt GD

更新日期：1994-11-15 00:00:00

abstract：:We investigated the effect on cell death of reactive oxygen species induced by water-soluble cationic metalloporphyrins with superoxide dismutase (SOD) activity. The SOD activity of 5,10,15,20-tetrakis(4-N-methylpyridyl)]porphine (MPy(4)P) containing Fe, Mn or Cu was measured using a cytochrome c assay by the xanthine...

journal_title：Journal of inorganic biochemistry

authors： Ohse T,Nagaoka S,Arakawa Y,Kawakami H,Nakamura K

更新日期：2001-06-01 00:00:00

abstract：:Microperoxidase 8 (MP8) is able to react with alkyl- and aryl-isonitriles (RNC) both in its reduced and oxidized states, to form MP8Fe(II)- and MP8Fe(III)-CNR complexes. The coordination and spin states of these complexes have been fully characterized by UV-visible and resonance Raman spectroscopies. Both MP8Fe(II)- a...

journal_title：Journal of inorganic biochemistry

authors： Ricoux R,Lecomte S,Policar C,Boucher JL,Mahy JP

更新日期：2005-05-01 00:00:00

abstract：:Ten new vanadocene complexes bearing N,N'-chelating ligands were prepared, characterized, and their cytotoxicity toward a panel of cancer cells was measured. Structures of four vanadocene compounds were determined by single crystal X-ray diffraction analysis. Complexes containing 1,2-bis(phenylimino)acenaphthene (bian...

journal_title：Journal of inorganic biochemistry

authors： Melounková L,Machálková A,Havelek R,Honzíček J,Řezáčová M,Císařová I,Peterová E,Vinklárek J

更新日期：2019-06-01 00:00:00

abstract：:In the presence of magnesium, enolase catalyzes the dehydration of 2-phospho-d-glycerate (PGA) to phosphoenolpyruvate (PEP) in glycolysis and the reverse reaction in gluconeogensis at comparable rates. The structure of human neuron specific enolase (hNSE) crystals soaked in PGA showed that the enzyme is active in the ...

journal_title：Journal of inorganic biochemistry

authors： Qin J,Chai G,Brewer JM,Lovelace LL,Lebioda L

更新日期：2012-06-01 00:00:00

abstract：:The synthesis of the Co(III) porphyrin octapeptide N-acetyl-Co(III) microperoxidase-8 (NAcCoMP8) is described. NAcCoMP8 provides a means of comparing and contrasting the chemistry of Co(III) porphyrins and corrins to assess the influence of the macrocycle. Log K values, and ΔH and ΔS, for the coordination of anionic (...

journal_title：Journal of inorganic biochemistry

authors： Mathura S,Sannasy D,de Sousa AS,Perry CB,Navizet I,Marques HM

更新日期：2013-06-01 00:00:00