A potentiometric and spectroscopic study of the proton and copper(II) complexes of methionine enkephalin and some related ligands.

abstract：:Electron paramagnetic resonance (e.p.r.) studies of thin DNA-chelate films indicate that both the water soluble planar macrocyclic chelates, cobalt (II) tetra (2,3-N-methylpyridinium) porphyrazine (cobalt (II) TMTPPA), and vanadyl (II) 5,10,15,20-tetra-(4-methylpyridinium) porphyrin (Vo (II) TMTPyP) can bind to calf t...

journal_title：Journal of inorganic biochemistry

authors： Dougherty G

更新日期：1988-10-01 00:00:00

abstract：:Nearly all microbes require iron for growth. The low concentration of iron found in the ocean makes iron acquisition a particularly difficult task. In response to these low iron conditions, many bacteria produce low-molecular-weight iron-binding molecules called siderophores to aid in iron uptake. We report herein the...

journal_title：Journal of inorganic biochemistry

authors： Gauglitz JM,Zhou H,Butler A

更新日期：2012-02-01 00:00:00

abstract：:Three vanadium complexes of chlorodipicolinic acid (4-chloro-2,6-dipicolinic acid) in oxidation states III, IV, and V were prepared and their properties characterized across the oxidation states. In addition, the series of hydroxylamido, methylhydroxylamido, dimethylhydroxylamido, and diethylhydroxylamido complexes we...

journal_title：Journal of inorganic biochemistry

authors： Smee JJ,Epps JA,Ooms K,Bolte SE,Polenova T,Baruah B,Yang L,Ding W,Li M,Willsky GR,la Cour A,Anderson OP,Crans DC

更新日期：2009-04-01 00:00:00

abstract：:Two new diMn(III) complexes [Mn(2)(III)L(1)(mu-AcO)(mu-MeO)(methanol)(2)]Br (1) and [Mn(2)(III)L(2)(mu-AcO)(mu-MeO)(methanol)(ClO(4))] (2) (L(1)H(3)=1,5-bis(2-hydroxybenzophenylideneamino)pentan-3-ol; L(2)H(3)=1,5-bis(2-hydroxynaphtylideneamino)pentan-3-ol) were synthesized and structurally characterized. Structural s...

journal_title：Journal of inorganic biochemistry

authors： Biava H,Palopoli C,Shova S,De Gaudio M,Daier V,González-Sierra M,Tuchagues JP,Signorella S

更新日期：2006-10-01 00:00:00

abstract：:Recent studies of the reaction mechanism of the molybdenum-containing enzyme xanthine oxidase are presented. The pH-dependence of both the steady-state and rapid reaction kinetics of the enzyme exhibits is bell-shaped, with pK(a)s for the acid and alkaline limbs of 6.6 and 7.4, respectively. These are assigned to ioni...

journal_title：Journal of inorganic biochemistry

authors： Choi EY,Stockert AL,Leimkühler S,Hille R

更新日期：2004-05-01 00:00:00

abstract：:Bovine calmodulin, spin-labeled at tyrosine-99, has been utilized in electron paramagnetic resonance (EPR) studies to investigate calmodulin interactions with Ca(II), Cd(II), and Mg(II). The addition of either Ca(II) or Cd(II) to apo-calmodulin results in a complex capable of activating target enzymes, such as 3', 5'-...

journal_title：Journal of inorganic biochemistry

authors： You GF,Buccigross JM,Nelson DJ

更新日期：1990-02-01 00:00:00

abstract：:There is considerable interest today for the reactions of anticancer metallodrugs with proteins as these interactions might feature processes that are crucial for the biodistribution, the toxicity and even the mechanism of action of this important group of anticancer agents. We survey here the results of research acti...

journal_title：Journal of inorganic biochemistry

authors： Casini A,Guerri A,Gabbiani C,Messori L

更新日期：2008-05-01 00:00:00

abstract：:Alpha-glucosidase is considered to be an important target for the treatment of noninsulin-dependent diabetes. In this work, the inhibitory effects of polyoxometalates (POMs) affected by three different factors (heteroatom, transition metal substitution element and vanadium substitution number) on α-glucosidase were st...

journal_title：Journal of inorganic biochemistry

authors： Chi G,Wang L,Chen B,Li J,Hu J,Liu S,Zhao M,Ding X,Li Y

更新日期：2019-10-01 00:00:00

abstract：:Four binuclear phosphanesilver(I) dithiocarbamates, {cyclohexyl3PAg(S2CNRR')}2 for R = R' = Et (1), CH2CH2 (2), CH2CH2OH (3) and R = Me, R' = CH2CH2OH (4) have been synthesised and characterised by spectroscopy and crystallography, and feature tri-connective, μ2-bridging dithiocarbamate ligands and distorted tetrahedr...

journal_title：Journal of inorganic biochemistry

authors： Tan YJ,Tan YS,Yeo CI,Chew J,Tiekink ERT

更新日期：2019-03-01 00:00:00

abstract：:Methanobactins are copper-binding ligands produced by aerobic methanotrophic microorganisms. A quantitative understanding of their potential role in methanotrophic copper acquisition requires the investigation of their copper complexes under relevant pH conditions. In this study, a chemical speciation model describing...

journal_title：Journal of inorganic biochemistry

authors： Pesch ML,Christl I,Hoffmann M,Kraemer SM,Kretzschmar R

更新日期：2012-11-01 00:00:00

abstract：:A series of new heterometallic gold(I) thiolates containing ferrocenyl-phoshines were synthesized. Their antimicrobial properties were studied and compared to that of FDA-approved drug, auranofin (Ridaura), prescribed for the treatment of rheumatoid arthritis. MIC in the order of one digit micromolar were found for mo...

journal_title：Journal of inorganic biochemistry

authors： Hokai Y,Jurkowicz B,Fernández-Gallardo J,Zakirkhodjaev N,Sanaú M,Muth TR,Contel M

更新日期：2014-09-01 00:00:00

abstract：:The reaction between reduced Pseudomonas cytochrome c551 and cytochrome oxidase with two inorganic metal complexes, Co(phen)3(3+) and Mn(CyDTA)(H2O)-, has been followed by stopped-flow spectrophotometry. The electron transfer to cytochrome c551 by both reactants is a simple process, characterized by the following seco...

journal_title：Journal of inorganic biochemistry

authors： Tordi MG,Silvestrini MC,Adzamli K,Brunori M

更新日期：1987-07-01 00:00:00

abstract：:The binding of Ru(phen)(2)dppz(2+) (dppz=dipyrido[3,2-a:2',3'-c]phenazine) to DNA was investigated at pH 7.0 and 25 degrees C using stopped-flow and spectrophotometric methods. Equilibrium measurements show that two modes of binding, whose characteristics depend on the polymer to dye ratio (C(P)/C(D)), are operative. ...

journal_title：Journal of inorganic biochemistry

authors： Biver T,Cavazza C,Secco F,Venturini M

更新日期：2007-03-01 00:00:00

abstract：:The 134 amino acid DNase domain of colicin E9 contains a zinc-finger-like HNH motif that binds divalent transition metal ions. We have used 1D 1H and 2D 1H-15N NMR methods to characterise the binding of Co2+, Ni2+ and Zn2+ to this protein. Data for the Co2+-substituted and Ni2+-substituted proteins show that the metal...

journal_title：Journal of inorganic biochemistry

authors： Hannan JP,Whittaker SB,Hemmings AM,James R,Kleanthous C,Moore GR

更新日期：2000-04-01 00:00:00

abstract：:Selenium is an essential trace element for humans and other animals, and there is mounting evidence for the efficacy of certain forms of selenium as cancer-chemopreventive compounds. However, over the years, numerous elements such as As, Cu, Zn, Cd, Hg, Sn, Pb, Ni, Co, Sb, Bi, Ag, Au, and Mo have been found to inhibit...

journal_title：Journal of inorganic biochemistry

authors： Zeng H,Uthus EO,Combs GF Jr

更新日期：2005-06-01 00:00:00

abstract：:We study the thermal unfolding of amicyanin by quantifying the resiliency of the native state to structural perturbations. Three signatures characterizing stages of unfolding are identified. The first signature, lateral extension of the polypeptide chain, is calculated directly from the reported crystallographic data....

journal_title：Journal of inorganic biochemistry

authors： Kozak JJ,Gray HB,Garza-López RA

更新日期：2018-02-01 00:00:00

abstract：:Kinetic evidence for the role of divalent metal ions in the phosphotransferase activity of polidocanol-solubilized alkaline phosphatase from osseous plate is reported. Ethylenediamine tetreacetate, 1,10-phenanthrolin, and Chelex-100 were used to prepare metal-depleted alkaline phosphatase. Except for Chelex-100, eithe...

journal_title：Journal of inorganic biochemistry

authors： Ciancaglini P,Pizauro JM,Leone FA

更新日期：1997-04-01 00:00:00

abstract：:The effect of the lanthanide(III) complexes [Gd(1,4,7,10-tetraazacyclododecane-N,N',N", N"'-tetrakis(methylenephosphonate))]5- (Gd-DOTP) and La-DOTP on the oxygen binding and spectroscopic properties of human adult and fetal hemoglobin (HbA and HbF, respectively) has been investigated. The affinity of Gd-DOTP and La-D...

journal_title：Journal of inorganic biochemistry

authors： Aime S,Fasano M,Paoletti S,Bellelli A,Coletta M,Ascenzi P

更新日期：1998-08-01 00:00:00

abstract：:The single mitochondrial type I [2Fe-2S] ferredoxin of the fission yeast Schizosaccharomyces pombe is produced as the carboxy terminal part of the electron-transfer-protein 1 (etp1) and cleaved off during mitochondrial import [Biochemistry 41 (2002) 2311-2321]. The UV/Vis (UV-visible) spectrum of the purified recombin...

journal_title：Journal of inorganic biochemistry

authors： Schiffler B,Bureik M,Reinle W,Müller EC,Hannemann F,Bernhardt R

更新日期：2004-07-01 00:00:00

abstract：:Arginine 56 in the beta subunit (betaArg56) of the iron-containing nitrile hydratase (NHase), one of the strongly conserved residues within the NHase family, is known to form hydrogen bonds to the sulfinyl (-SO2H) and sulfenyl (-SOH) groups of the post-translationally modified cysteine residues in the catalytic center...

journal_title：Journal of inorganic biochemistry

authors： Piersma SR,Nojiri M,Tsujimura M,Noguchi T,Odaka M,Yohda M,Inoue Y,Endo I

更新日期：2000-07-01 00:00:00

abstract：:A series of new copper (II) complexes with 2-methyl-3-amino(3H)-quinazolin-4-one (MAQ) and various anions (Cl-, Br-, ClO(-)4, NO(-)3, SCN-, and SO(2-)4 was prepared. Their structures and properties were characterized by elemental analysis, IR, UV-Vis and ESR spectroscopy, molar conductivity, and magnetic moment measur...

journal_title：Journal of inorganic biochemistry

authors： Ramadan AM

更新日期：1997-02-15 00:00:00

abstract：:The potential of hyphenated techniques based on a combination of microbore reversed-phase (RP) HPLC or capillary zone electrophoresis (CZE) with inductively coupled plasma (ICP) or electrospray (ES) mass spectrometry (MS) was demonstrated for the characterization of metal complexes with metallothionein in rat liver an...

journal_title：Journal of inorganic biochemistry

authors： Połec K,Peréz-Calvo M,García-Arribas O,Szpunar J,Ribas-Ozonas B,Lobinski R

更新日期：2002-01-15 00:00:00

abstract：:One-electron reduction and oxidation induced by vanadium complexes are demonstrated to be useful in oxidative and reductive transformations of carbonyl compounds. The redox interaction between vanadium complexes and redox-active ligands is achieved with coenzyme PQQ and polyanilines that afford the corresponding redox...

journal_title：Journal of inorganic biochemistry

authors： Hirao T

更新日期：2000-05-30 00:00:00

abstract：:Tree laccase, a multi-copper oxidase, has been studied as a copper donor in conjunction with the demetalated forms of three blue copper proteins. Copper transfer could be observed under reducing conditions in the absence of air. Only about 10% of the total copper in laccase could be transferred regardless of the amoun...

journal_title：Journal of inorganic biochemistry

authors： Meadows KA,Morie-Bebel MM,McMillin DR

更新日期：1991-03-01 00:00:00

abstract：:The structural spectroscopic, and thermal properties of a complex of sulfacetamide (Hsacm) with Cu(II) have been investigated. The complex [Cu(Hsacm)2(NO3)2] crystallizes in the monoclinic system, space group P2(1)/n. The cell dimensions are a = 7.696(7) A, b = 8.017(7) A, c = 19.230(10), beta = 110.80(1) degree, V = ...

journal_title：Journal of inorganic biochemistry

authors： Blasco F,Ortiz R,Perelló L,Borrás J,Amigó J,Debaerdemaeker T

更新日期：1994-02-01 00:00:00

abstract：:Recent findings on the photophysical investigations of several cofacial bisporphyrin dyads for through space singlet and triplet energy transfers raised several serious questions about the mechanism of the energy transfers and energy migration in the light harvesting devices, notably LH II, in the heavily studied purp...

journal_title：Journal of inorganic biochemistry

authors： Harvey PD,Stern C,Gros CP,Guilard R

更新日期：2008-03-01 00:00:00

abstract：:The use of chelating agents for iron and aluminum in different clinical applications has found increasing attention in the last thirty years. Desferal, deferiprone and deferasirox, chelating agents nowadays in use, are based on hydroxamic groups, hydroxyl-substituted pyridinones or aromatic ring systems. With the aim ...

journal_title：Journal of inorganic biochemistry

authors： Toso L,Crisponi G,Nurchi VM,Crespo-Alonso M,Lachowicz JI,Santos MA,Marques SM,Niclós-Gutiérrez J,González-Pérez JM,Domínguez-Martín A,Choquesillo-Lazarte D,Szewczuk Z

更新日期：2013-10-01 00:00:00

abstract：:Four water soluble complexes of the type [M(bpy)(a-x)]NO3, where M is Pd(II) or Pt(II), bpy is 2,2-bipyridine, and a-x is anion of 2-pyridinecarboxylic acid or 2-pyrazinecarboxylic acid, have been found to bind calf thymus DNA, possibly through hydrogen binding. [M(bpy)(2-py)]NO3 complexes (2-py is an anion of 2-pyrid...

journal_title：Journal of inorganic biochemistry

authors： Mansuri-Torshizi H,Srivastava TS,Chavan SJ,Chitnis MP

更新日期：1992-10-01 00:00:00

abstract：:We report new anticancer prodrugs, platinum(IV) derivatives of oxaliplatin conjugated with valproic acid (VPA), a well-known drug having histone deacetylase inhibitory activity. Like most platinum(IV) derivatives, the cytotoxicity of the conjugates was lower in cell culture than that of oxaliplatin, but greater than t...

journal_title：Journal of inorganic biochemistry

authors： Novohradsky V,Zerzankova L,Stepankova J,Vrana O,Raveendran R,Gibson D,Kasparkova J,Brabec V

更新日期：2014-11-01 00:00:00

abstract：:The substitution of tetradentate bispidine ligands with rhodamine and cyanine dye molecules, coupled to an amine donor, forming an amide as potential fifth donor, is described. Bispidines are known to lead to very stable Cu(II) complexes, and the coordination to Cu(II) was expected to efficiently quench the fluorescen...

journal_title：Journal of inorganic biochemistry

authors： Brox D,Comba P,Herten DP,Kimmle E,Morgen M,Rühl CL,Rybina A,Stephan H,Storch G,Wadepohl H

更新日期：2015-07-01 00:00:00