Circulating dendritic cells subsets and CD4+Foxp3+ regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome.

abstract：INTRODUCTION:Increased levels of Wilms' tumor (WT1) mRNA have been used to establish risk categories in patients with acute myeloid leukemia (AML). Raised values of WT1 have been associated with progression in myelodysplastic syndrome (MDS). METHODS:We retrospectively analyzed the available bone marrow (BM) samples fr...

journal_title：European journal of haematology

authors： Santaliestra M,Garrido A,Carricondo M,Bussaglia E,Pratcorona M,Blanco ML,Gich I,Hoyos M,Esquirol A,García-Cadenas I,Brunet S,Martino R,Sierra J,Nomdedéu JF

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:The mutational status of the immunoglobulin (Ig) V(H) gene in B-cell chronic lymphocytic leukaemia (B-CLL) identifies two subgroups of patients with significantly different outcomes. We investigated the association of ZAP-70 expression with IgVH mutational status in B-CLL by quantifying ZAP-70 mRNA, to evalua...

journal_title：European journal of haematology

authors： Catherwood MA,Matthews C,Niblock R,Dobbin E,Morris TC,Alexander HD

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:Imatinib (Glivec, STI571) has been successfully used in patients with chronic myelogenous leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome (Ph). We used imatinib interim therapy for four consecutive patients with newly diagnosed Ph+ acute myeloid leukemia (AML). We monitored the pat...

journal_title：European journal of haematology

authors： Cho BS,Kim HJ,Lee S,Eom KS,Min WS,Lee JW,Kim CC

更新日期：2007-08-01 00:00:00

abstract：:Immune reconstitution may be delayed after CD34-selected compared with unmanipulated autologous peripheral blood stem cell transplantation (PBSCT), resulting in a theoretically increased risk of infections. In a case-control matched study we compared the incidence of infection in 25 recipients of CD34-selected PBSC (C...

journal_title：European journal of haematology

authors： Frère P,Pereira M,Fillet G,Beguin Y

更新日期：2006-02-01 00:00:00

abstract：:Forty-one patients with codon 17, A-T mutation of beta-thalassemia, which is commonly found in Thailand, were studied to determine whether it is possible to predict phenotypic severity from genetic factors. The clinical phenotype of homozygotes for codon 17, A-T and compound heterozygotes for codon 17, A-T and beta+-t...

journal_title：European journal of haematology

authors： Laosombat V,Wongchanchailert M,Sattayasevana B,Wiriyasateinkul A,Fucharoen S

更新日期：2001-02-01 00:00:00

abstract：:The value of Y-body study for assessment of haemopoietic engraftment was analyzed in 50 consecutive patients submitted to allogeneic bone marrow transplantation (BMT) (sex-matched in 28 cases, sex-mismatched in 22). The study was performed weekly on bone marrow and peripheral blood smears in all cases, and alveolar ma...

journal_title：European journal of haematology

authors： Ribera JM,Feliu E,Rozman C,Grañena A,Xaubet A,Vives-Corrons JL,Ballesta F

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:To assess the importance of the quality of response and of early relapse in unselected elderly patients with myeloma treated upfront with novel agents. METHODS:We analyzed 135 unselected transplant-ineligible patients older than 65 yr who were treated upfront with novel agent-based regimens in a single cent...

journal_title：European journal of haematology

authors： Migkou M,Kastritis E,Roussou M,Gkotzamanidou M,Gavriatopoulou M,Nikitas N,Mparmparoussi D,Matsouka C,Gika D,Terpos E,Dimopoulos MA

更新日期：2011-10-01 00:00:00

abstract：:Little is known about the S100B⁺ lymphocytes, which are unique human peripheral blood lymphocytes (PBL) containing the S100B protein. It has recently been shown that S100B is released from various types of S100B⁺ cells and exhibits varied cytokine-like activities. In this study, we precisely characterized the S100B⁺ l...

journal_title：European journal of haematology

authors： Miki Y,Gion Y,Mukae Y,Hayashi A,Sato H,Yoshino T,Takahashi K

更新日期：2013-02-01 00:00:00

abstract：:A 59-yr-old man developed fevers, shortness of breath, persistent cough and weight loss, shortly after initiation of therapy with interferon-alpha 2a and cytosine arabinoside for treatment of chronic myelogenous leukemia. Radiologic pulmonary infiltrates and lung tissue biopsy were consistent with bronchiolitis oblite...

journal_title：European journal of haematology

authors： Patel M,Ezzat W,Pauw KL,Lowsky R

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Myelodysplastic syndromes (MDS) and aplastic anemia (AA) are the most common anemias that require transfusion therapy in Japan. This retrospective survey investigated relationships between iron overload, chelation practices, and morbidity/mortality in patients with these diseases. METHOD:Medical histories of...

journal_title：European journal of haematology

authors： Takatoku M,Uchiyama T,Okamoto S,Kanakura Y,Sawada K,Tomonaga M,Nakao S,Nakahata T,Harada M,Murate T,Ozawa K,Japanese National Research Group on Idiopathic Bone Marrow Failure Syndromes.

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:Combined high-dose Interferon-alpha and psoralen plus ultraviolet A irradiation (PUVA) have been reported to be effective in the treatment of early mycosis fungoides (MF); however, our study is the first controlled prospective study in the literature exploring the activity and tolerability of the combination...

journal_title：European journal of haematology

authors： Rupoli S,Goteri G,Pulini S,Filosa A,Tassetti A,Offidani M,Filosa G,Mozzicafreddo G,Giacchetti A,Brandozzi G,Cataldi I,Barulli S,Ranaldi R,Scortechini AR,Capretti R,Fabris G,Leoni P,Marche Regional Multicentric Study Gro

更新日期：2005-08-01 00:00:00

abstract：:10 patients with CLL and 2 with CML were treated with gradually increasing doses of 1 alpha(OH)D3, up to 4 micrograms daily during 6 wk. 3 patients with preleukemia and 1 with myelofibrosis were treated with 2 micrograms daily of 1 alpha(OH)D3 for a prolonged period up to 17 wk. The treatment with 1 alpha (OH)D3 did n...

journal_title：European journal of haematology

authors： Wieslander SB,Mortensen BT,Binderup L,Nissen NI

更新日期：1987-07-01 00:00:00

abstract：:To investigate the role of protein phosphorylation in the early phase of EPO-mediated signal transduction, we EPO-stimulated a murine erythroid cell line ELM-I-1 transformed by plasmids comprised of the c-fos enhancer/promoter linked to the luciferase gene. Using this reporter gene system, we previously showed that EP...

journal_title：European journal of haematology

authors： Tsuda H,Huang RW,Takatsuki K

更新日期：1994-04-01 00:00:00

abstract：:This study shows that the ingestion of ethanol provokes alterations in iron metabolism which may lead to iron overload. Impaired release of reticuloendothelial iron was shown by a decrease of the maximum red blood cell utilization when radioactive iron was supplied as colloidal iron. An impairment in the erythropoieti...

journal_title：European journal of haematology

authors： Sánchez J,Casas M,Rama R

更新日期：1988-10-01 00:00:00

abstract：OBJECTIVE:The extent of disease in patients with multiple myeloma or related conditions may be difficult to assess. In previous small studies, both FDG-PET (PET) and Tc-99m sestamibi scans (MIBI) have identified sites of occult disease in myeloma. METHODS:We reviewed the results for patients at our institution who hav...

journal_title：European journal of haematology

authors： Mileshkin L,Blum R,Seymour JF,Patrikeos A,Hicks RJ,Prince HM

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (CPI) are widely used in modern oncology and have improved the prognosis of lung cancer, malignant melanoma, and other malignancies. Unlike cytotoxic chemotherapy, drugs such as nivolumab, pembrolizumab, and ipilimumab are associated with immune-related adverse effects. We recent...

journal_title：European journal of haematology

authors： Tanios GE,Doley PB,Munker R

更新日期：2019-02-01 00:00:00

abstract：:A hairy cell leukaemia (HCL) patient is presented in whom the peripheral blood mononuclear cells (PBMCs) carried suppressor T-cell markers (CD3+, CD2+, CD8+/CD4-, CD38+). Analysis of genomic DNA of PBMNC showed the presence of a monoclonal population of T cells, the T-cell receptor (TCR) beta-chain gene being rearrang...

journal_title：European journal of haematology

authors： Demeter J,Pálóczi K,Földi J,Hokland M,Hokland P,Benczúr M,Lehoczky D

更新日期：1989-10-01 00:00:00

abstract：INTRODUCTION:Prenatal diagnosis of severe alpha- and beta-thalasssemia diseases is usually performed by DNA analysis. OBJECTIVE:To establish a simple method, we have evaluated the reliability of prenatal diagnosis by fetal blood analysis using automated capillary electrophoresis system. METHODS:Forty-seven fetal bloo...

journal_title：European journal of haematology

authors： Srivorakun H,Fucharoen G,Sae-Ung N,Sanchaisuriya K,Ratanasiri T,Fucharoen S

更新日期：2009-07-01 00:00:00

abstract：:Neonatal alloimmune thrombocytopenia (NAIT) occurs because of transplacentally acquired maternal platelet alloantibodies. Most of the alloantibodies are against human platelet antigens, but the alloantibody against CD36 is rare. A full-term female baby was delivered by a mother who experienced two spontaneous abortion...

journal_title：European journal of haematology

authors： Taketani T,Ito K,Mishima S,Kanai R,Uchiyama A,Hirata Y,Kumakura S,Ishikura H,Yamaguchi S

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Interleukin-6 (IL-6) is a multifunctional cytokine that plays roles in the immune response, inflammation and hematopoiesis. Serum IL-6 levels have reported to reflect disease severity and high tumor burden in multiple myeloma (MM) patients and to correlate with several other laboratory parameters. Serum-solu...

journal_title：European journal of haematology

authors： Hatzimichael EC,Christou L,Bai M,Kolios G,Kefala L,Bourantas KL

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:More than 90% of children with sickle cell anemia (SCA) lose splenic function by the age of 2 yrs. Splenic function may improve with hydroxyurea, but previous studies are conflicting. We prospectively evaluated the effect of hydroxyurea on splenic filtrative function. METHODS:Children with SCA enrolled in t...

journal_title：European journal of haematology

authors： Nottage KA,Ware RE,Winter B,Smeltzer M,Wang WC,Hankins JS,Dertinger SD,Shulkin B,Aygun B

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Anthracyclines and cytarabine are cornerstones for intensive chemotherapy in acute myeloid leukemia (AML). The goals of this study were to comprehensively assess deviations from theoretical doses and the impact of body-surface area (BSA) on patients' characteristics, physicians' strategy, dose adjustment, an...

journal_title：European journal of haematology

authors： Cahu X,Carré M,Recher C,Pigneux A,Hunault-Berger M,Vey N,Chevallier P,Delaunay J,Gyan E,Lioure B,Bonmati C,Himberlin C,Hicheri Y,Guillerm G,Didier B,Larosa F,Ojeda-Uribe M,Bernard M,Bene MC,Ifrah N,Cahn JY

更新日期：2017-05-01 00:00:00

abstract：:This study describes a retrospective analysis on the transplant outcome of 56 consecutive patients with myelodysplastic syndrome (MDS) according to their response to hypomethylating agents (HMA). While 2-yr disease-free survival (DFS) of patients who transformed to acute myeloid leukemia (n = 12) was 25%, that of the ...

journal_title：European journal of haematology

authors： Yahng SA,Yoon JH,Shin SH,Lee SE,Cho BS,Lee DG,Eom KS,Lee S,Min CK,Kim HJ,Cho SG,Kim DW,Lee JW,Min WS,Kim TG,Park CW,Kim YJ

更新日期：2013-02-01 00:00:00

abstract：:In childhood-onset acute myeloid leukaemia (AML) the clinical value of karyotypic aberrations is now acknowledged, although there is still debate concerning the prognostic significance of some events. To add to this knowledge, cytogenetic analysis was performed on a consecutive series of 84 childhood AML patients diag...

journal_title：European journal of haematology

authors： Betts DR,Ammann RA,Hirt A,Hengartner H,Beck-Popovic M,Kuhne T,Nobile L,Caflisch U,Wacker P,Niggli FK

更新日期：2007-06-01 00:00:00

abstract：:506 unselected, previously untreated patients with Hodgkin's disease were treated at the Finsen Institute between 1969 and 1983. The prognostic significance of age, sex, stage, systemic symptoms, histologic subtype, number of involved nodal regions, total tumour burden (peripheral + intrathoracic nodal tumour burden, ...

journal_title：European journal of haematology

authors： Specht L,Nissen NI

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:Central retinal vein occlusion (CRVO) and central retinal artery occlusion (CRAO) are common disorders associated with risk factors for atherosclerosis. Protein Z is a cofactor for the inactivation of activated factor X (Xa) by the protein Z dependent protease inhibitor. Protein Z deficiency was recently lin...

journal_title：European journal of haematology

authors： Koren-Michowitz M,Eting E,Rahimi-Levene N,Garach-Jehoshua O,Volcheck Y,Kornberg A

更新日期：2005-11-01 00:00:00

abstract：:Mantle cell lymphoma (MCL) is an aggressive B-cell non-Hodgkin lymphoma (NHL) characterized by the translocation t(11;14)(q13;q32). This lymphoma exhibits a poor prognosis and remains incurable with standard chemotherapy approaches. Recently, we have shown that a majority of patients with acute-type adult T-cell leuke...

journal_title：European journal of haematology

authors： Liu F,Yoshida N,Suguro M,Kato H,Karube K,Arita K,Yamamoto K,Tsuzuki S,Oshima K,Seto M

更新日期：2013-01-01 00:00:00

abstract：:Reduced-intensity conditioning regimens have demonstrated lower toxicity but increased relapse rates in the context of allogeneic hematopoietic stem cell transplantation (aSCT) for patients with acute myelogenous leukemia (AML). The FLAMSA- reduced-intensity conditioning (RIC) regimen, combining a cytoreductive and a ...

journal_title：European journal of haematology

authors： Holtick U,Shimabukuro-Vornhagen A,Chakupurakal G,Theurich S,Leitzke S,Burst A,Hallek M,von Bergwelt-Baildon M,Scheid C,Chemnitz JM

更新日期：2016-05-01 00:00:00

abstract：:Ibrutinib has now been approved for treatment of chronic lymphocytic leukemia (CLL) in both front-line setting and as later-line treatment. However, knowledge about the outcomes and adverse events (AE) among patients at a population-based level is still limited. OBJECTIVES:To report outcomes and AEs in a population-b...

journal_title：European journal of haematology

authors： Aarup K,Rotbain EC,Enggaard L,Pedersen RS,Bergmann OJ,Thomsen RH,Frederiksen M,Frederiksen H,Nielsen T,Christiansen I,Andersen MA,Niemann CU

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVES:To assess the molecular basis of phenotypic heterogeneity in north Indian patients with thalassemia major (TM). METHODS:To determine the clinical severity, 130 patients of TM were studied for the age of first presentation and frequency of blood transfusion. The type of beta mutations, Xmn-1(G)gamma polymorp...

journal_title：European journal of haematology

authors： Sharma N,Das R,Kaur J,Ahluwalia J,Trehan A,Bansal D,Panigrahi I,Marwaha RK

更新日期：2010-06-01 00:00:00