Chronotherapeutics in a psychiatric ward.

Abstract:

:Psychiatric chronotherapeutics is the controlled exposure to environmental stimuli that act on biological rhythms in order to achieve therapeutic effects in the treatment of psychiatric conditions. In recent years some techniques (mainly light therapy and sleep deprivation) have passed the experimental developmental phase and reached the status of powerful and affordable clinical interventions for everyday clinical treatment of depressed patients. These techniques target the same brain neurotransmitter systems and the same brain areas as do antidepressant drugs, and should be administered under careful medical supervision. Their effects are rapid and transient, but can be stabilised by combining techniques among themselves or together with common drug treatments. Antidepressant chronotherapeutics target the broadly defined depressive syndrome, with response and relapse rates similar to those obtained with antidepressant drugs, and good results are obtained even in difficult-to-treat conditions such as bipolar depression. Chronotherapeutics offer a benign alternative to more radical treatments of depression for the treatment of severe depression in psychiatric wards, but with the advantage of rapidity of onset.

journal_name

Sleep Med Rev

journal_title

Sleep medicine reviews

authors

Benedetti F,Barbini B,Colombo C,Smeraldi E

doi

10.1016/j.smrv.2007.06.004

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

509-22

issue

6

eissn

1087-0792

issn

1532-2955

pii

S1087-0792(07)00088-3

journal_volume

11

pub_type

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