Abstract：
:Obstructive sleep apnea is characterized by recurrent obstruction of the upper airway during sleep, resulting in episodic reductions in blood oxygen saturation and arousals from sleep. Mandibular repositioning appliances (MRAs) which are worn intra-orally at night, mechanically advance the mandible to help maintain a patent oropharygeal airway and have been proven to be an effective alternative for continuous positive airway pressure in the treatment of obstructive sleep apnea. Titratable MRAs are designed to gradually protrude the mandible applying an easy-to-use mechanical advancing mechanism, until a protrusive position with positive effect on sleep apnea is reached. Considering the relatively low-tech approach of the basic advancement mechanism, the interest in the mechanistic element of the dental treatment of obstructive sleep apnea has increased. The present paper provides an overview of the different titration protocols described in the recent literature together with a discussion of both the clinical and mechanical aspects of treatment. At present, a consensus exists that an optimal titration protocol is of primary importance to achieve a successful treatment outcome with an MRA. To date however, there is no consensus on how to define the optimal titration protocol.
journal_name
Sleep Med Revjournal_title
Sleep medicine reviewsauthors
Dieltjens M,Vanderveken OM,Heyning PH,Braem MJdoi
10.1016/j.smrv.2011.06.002subject
Has Abstractpub_date
2012-04-01 00:00:00pages
177-85issue
2eissn
1087-0792issn
1532-2955pii
S1087-0792(11)00069-4journal_volume
16pub_type
杂志文章,评审abstract：:Sleep disordered breathing (SDB) is a common disorder in both adults and children and is caused by the obstruction of the upper airway during sleep. Unlike adults, most cases of paediatric SDB are due to the presence of enlarged tonsils and adenoids, thus the main treatment option is adenotonsillectomy (T&A). It is we...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2012.04.004
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journal_title：Sleep medicine reviews
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pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2018-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2021-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章
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更新日期：2001-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2018-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.06.001
更新日期：2017-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2004.07.005
更新日期：2004-12-01 00:00:00
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journal_title：Sleep medicine reviews
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更新日期：2020-10-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.10.002
更新日期：2006-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/s1087-0792(98)90051-x
更新日期：1998-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2017.04.002
更新日期：2018-04-01 00:00:00
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journal_title：Sleep medicine reviews
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pub_type： 杂志文章,评审
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更新日期：2007-12-01 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2004-04-01 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2015-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2007-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,meta分析,评审
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更新日期：2018-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2020-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2020-04-01 00:00:00
