Short sleep duration predicts risk of metabolic syndrome: a systematic review and meta-analysis.

Abstract:

:Sleep duration has been suggested to play a key role in the development of metabolic syndrome (MS). However, the results have been inconsistent. The objective of this study was to clarify the association between sleep duration and MS risk. PubMed and Embase databases were searched for eligible publications. Pooled odds ratio (OR) with 95% confidence interval (CI) was calculated using random- or fixed-model. A total of 12 studies (18,720 MS cases and 70,833 controls) were included in the meta-analysis. Short sleep duration was significantly associated with increased risk of MS (OR = 1.27, 95%CI = 1.09-1.47, p = 0.002). Long sleep duration was not associated with increased risk of MS (OR = 1.07, 95%CI = 0.87-1.32, p = 0.535). Similar results were found in both men and women. The sensitivity analysis confirmed the stability of the results and no publication bias was detected. The present meta-analysis suggests that short rather than long sleep duration is significantly associated with risk of MS. Large-scale well-design prospective studies are required to further investigate the association between sleep duration and MS risk.

journal_name

Sleep Med Rev

journal_title

Sleep medicine reviews

authors

Xi B,He D,Zhang M,Xue J,Zhou D

doi

10.1016/j.smrv.2013.06.001

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

293-7

issue

4

eissn

1087-0792

issn

1532-2955

pii

S1087-0792(13)00071-3

journal_volume

18

pub_type

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