Abstract：
:Obstructive sleep apnea (OSA) is a common cause of daytime sleepiness for millions of Americans. It is also a disease associated with an increased likelihood of hypertension, cardiovascular disease, stroke, daytime sleepiness, motor vehicle accidents, and diminished quality of life. A number of population-based studies have shown that OSA is more common in men than in women and this discrepancy is often evident in the clinical setting. There are a number of pathophysiological differences to suggest why men are more prone to the disease than women. Although the exact mechanisms are unknown, differences in obesity, upper airway anatomy, breathing control, hormones, and aging are all thought to play a role. The purpose of this review was to examine the literature on gender differences in OSA and to analyze whether or not these differences in pathogenic mechanisms affect diagnosis or treatment.
journal_name
Sleep Med Revjournal_title
Sleep medicine reviewsauthors
Lin CM,Davidson TM,Ancoli-Israel Sdoi
10.1016/j.smrv.2007.11.003subject
Has Abstractpub_date
2008-12-01 00:00:00pages
481-96issue
6eissn
1087-0792issn
1532-2955pii
S1087-0792(07)00145-1journal_volume
12pub_type
杂志文章,评审abstract：:The psychiatric intervention, light therapy, grew from an intensive 25-year research focus on seasonal affective disorder (SAD). Dosing and timing strategies have been honed to optimize the antidepressant effect, and efficacy relative to placebo has provided the evidence base for widespread implementation. A persisten...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2007.06.003
更新日期：2007-12-01 00:00:00
abstract：:This review summarises data gathered on the KC phenomenon over the past 70 yr. The following issues are discussed: definitions, morphology and topography of KC, the regular participation in NREM sleep, elicitability features of evoked KC, autonomic and motor concomitants, relationship of KC with information processing...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.04.003
更新日期：2005-10-01 00:00:00
abstract：:On-call work is becoming an increasingly common work pattern, yet the human impacts of this type of work are not well established. Given the likelihood of calls to occur outside regular work hours, it is important to consider the potential impact of working on-call on stress physiology and sleep. The aims of this revi...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.06.001
更新日期：2017-06-01 00:00:00
abstract：:In addition to its role in vision, light exerts strong effects on behavior. Its powerful role in the modulation of mood is well established, yet remains poorly understood. Much research has focused on the effects of light on circadian rhythms and subsequent interaction with alertness and depression. The recent discove...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2011.09.002
更新日期：2012-10-01 00:00:00
abstract：:Obstructive sleep apnea is an underdiagnosed sleep-related breathing disorder affecting millions of people. Recurrent episodes of apnea/hypopnea result in intermittent hypoxia leading to oxidative stress. Obstructive sleep apnea is considered an independent risk factor for cardiovascular disease but the exact pathophy...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2019.03.010
更新日期：2019-08-01 00:00:00
abstract：:Melatonin is synthesized and secreted during the dark period of the light-dark cycle. Thus, melatonin has an obvious association with sleep, at least in diurnal animals. Rhythmic nocturnal melatonin secretion is directly generated by the circadian clock, located in mammals within the suprachiasmatic nuclei (SCN), and ...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/s1087-0792(98)90020-x
更新日期：1998-08-01 00:00:00
abstract：:Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is common during pregnancy, affecting approximately one in five pregnant women in Western countries. Many report moderate or severe symptoms and negative impact on sleep. There is very little information in the medical literature for practitioners on the manageme...
journal_title：Sleep medicine reviews
pub_type： 共识发展会议,杂志文章,实务指引,评审
doi：10.1016/j.smrv.2014.10.009
更新日期：2015-08-01 00:00:00
abstract：:Jetlag is a combination of travel fatigue and circadian misalignment resulting from air travel across time zones. Routinely recommended interventions based on circadian science include timely exposure to light and darkness (scheduled sleep), but the real-world effectiveness of these and other non-circadian strategies ...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2018.09.005
更新日期：2019-02-01 00:00:00
abstract：:Post-operative patients experience sleep disturbances. Animal studies demonstrate that general anaesthesia (GA) can disrupt circadian rhythms and cause changes in the molecular clock, indicating that anaesthesia contributes to post-operative circadian disruption. Here we review the effect of anaesthesia on the circadi...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.12.002
更新日期：2018-02-01 00:00:00
abstract：:Traumatic events have been increasingly recognized as important precipitants of clinically significant insomnia. Trauma is an extreme form of stressful life event that generates a sustained neurobiological response triggering the onset and maintenance of insomnia. Trauma may disrupt the normal sleep-wake regulatory me...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2015.01.008
更新日期：2016-02-01 00:00:00
abstract：:Sleep and sleep disorders are complex and highly variable phenotypes regulated by many genes and environment. The catechol-O-methyltransferase (COMT) gene is an interesting candidate, being one of the major mammalian enzymes involved in the catabolism of catecholamines. The activity of COMT enzyme is genetically polym...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2014.10.006
更新日期：2015-08-01 00:00:00
abstract：:There is considerable research evidence suggesting that sleep is biologically linked to mood disorders in adults. However, polysomographic and neuroendocrine studies in children and adolescents have not found consistent changes in sleep architecture paralleling adult major depression. This review provides a detailed d...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2004.09.006
更新日期：2005-04-01 00:00:00
abstract：:Restless legs syndrome (RLS) is a complex multifactorial disorder whose aetiology has yet to be fully elucidated. Some of the features of RLS, such as processing of sensations and activation of movement, may result from a dysfunction in spinal processing giving rise to a state of spinal hyperexcitability. In the curre...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2019.05.005
更新日期：2019-10-01 00:00:00
abstract：:Among the range of primary insomnia subtypes, those assigned such labels as subjective insomnia or sleep state misperception historically have been among the most intriguing yet challenging to understand and manage clinically. Such patients who produce seemingly normal polysomnograms often present rather compelling an...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1053/smrv.2002.0253
更新日期：2003-06-01 00:00:00
abstract：:Problems with sleep are reported to be common after stroke but the incidence and prevalence of insomnia and insomnia symptoms following stroke is not yet established. The aim of this review was to conduct a systematic review and meta-analysis of the incidence and prevalence of insomnia and insomnia symptoms in individ...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2019.101222
更新日期：2020-02-01 00:00:00
abstract：:Sleep disturbances during menopause are often attributed to nocturnal hot flashes and 'sweats' associated with changing hormone patterns. This paper is a comprehensive critical review of the research on the relationship between sleep disturbance and hot flashes in women. Numerous studies have found a relationship betw...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2004.07.005
更新日期：2004-12-01 00:00:00
abstract：:In recent years, strong evidence has emerged suggesting that insufficient duration, quality, and/or timing of sleep are associated with cardiovascular disease (CVD), and various mechanisms for this association have been proposed. Such associations may be related to endophenotypic features of the sleep homeostat and th...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.05.004
更新日期：2017-06-01 00:00:00
abstract：:Mammalian sleep emerges from attenuated activity in the ascending reticular arousal system (ARAS), the main arousal network of the brain. This system originates in the brainstem and activates the thalamus and cortex during wakefulness via a well-characterized 'bottom-up' pathway. Recent studies propose that a less inv...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2015.12.005
更新日期：2017-02-01 00:00:00
abstract：:Minority individuals in the United States (US) have an increased prevalence of obstructive sleep apnea (OSA) compared to their white/Caucasian counterparts. In general, adherence to positive airway pressure (PAP) therapy is poor and some studies suggest that PAP use among minority individuals is inferior to that of wh...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2017.04.002
更新日期：2018-04-01 00:00:00
abstract：:To date, continuous positive airway pressure (CPAP) is the most effective intervention in the treatment of obstructive sleep apnoea, but adherence to this treatment is often less than optimal. A variety of factors and interventions that influence and improve CPAP use have been examined. There is increasing recognition...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2013.03.002
更新日期：2014-04-01 00:00:00
abstract：:Sleep duration has been suggested to play a key role in the development of metabolic syndrome (MS). However, the results have been inconsistent. The objective of this study was to clarify the association between sleep duration and MS risk. PubMed and Embase databases were searched for eligible publications. Pooled odd...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.smrv.2013.06.001
更新日期：2014-08-01 00:00:00
abstract：:One of the most common sleep-related disorders is obstructive sleep apnea, characterized by a reduction of airflow while breathing during sleep and cause significant health problems. This disorder is mainly diagnosed in sleep labs with polysomnography, involving high costs and stress for the patient. To address this s...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2018.02.004
更新日期：2018-10-01 00:00:00
abstract：:Obstructive sleep apnea/hypopnea (OSAH) syndrome is a highly prevalent condition. Severe OSAH affects 2-6% of the population, although only 10% of subjects are correctly diagnosed and treated. OSAH is an important and unresolved public health care problem because of its role in the development of cardiovascular events...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2008.11.001
更新日期：2009-10-01 00:00:00
abstract：:Psychiatric chronotherapeutics is the controlled exposure to environmental stimuli that act on biological rhythms in order to achieve therapeutic effects in the treatment of psychiatric conditions. In recent years some techniques (mainly light therapy and sleep deprivation) have passed the experimental developmental p...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2007.06.004
更新日期：2007-12-01 00:00:00
abstract：:Magnesium supplementation is often suggested for restless legs syndrome (RLS) or period limb movement disorder (PLMD) based on anecdotal evidence that it relieves symptoms and because it is also commonly recommended for leg cramps. We aimed to review all articles reporting the effects of magnesium supplementation on c...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2019.101218
更新日期：2019-12-01 00:00:00
abstract：:After major non-cardiac surgery sleep pattern is usually disturbed with initial suppression of rapid eye movement sleep with a subsequent rebound during the first post-operative week. Deep sleep is also suppressed for several days after the operation and subjective sleep quality is impaired. The sleep disturbances see...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1053/smrv.2000.0121
更新日期：2001-04-01 00:00:00
abstract：:Dopaminergic drugs have been widely used over the last decades for the treatment of restless legs syndrome (RLS)/Willis-Ekbom disease (WED). While the majority of studies show an initial improvement in symptoms, longer studies and clinical experience show that either treatment efficacy decreases with time, and/or augm...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2018.01.001
更新日期：2018-10-01 00:00:00
abstract：:Sleep can improve the off-line memory consolidation of new items of declarative and non-declarative information in healthy subjects, whereas acute sleep loss, as well as sleep restriction and fragmentation, impair consolidation. This suggests that, by modifying the amount and/or architecture of sleep, chronic sleep di...
journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1016/j.smrv.2012.01.004
更新日期：2013-04-01 00:00:00
abstract：:Cognitive deficits and cardiovascular disease (CVD) are comorbid conditions frequently associated with obstructive sleep apnea (OSA). Oxygen free radical release and its differential regulation of cytokine synthesis and immune modulation resulting from OSA-related hypoxic events have been hypothesized as the underlyin...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.04.004
更新日期：2005-12-01 00:00:00
abstract：:With this systematic review we aimed to determine the prevalence of obstructive sleep apnea (OSA) in adults in the general population and how it varied between population sub-groups. Twenty-four studies out of 3807 found by systematically searching PubMed and Embase databases were included in this review. Substantial ...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.07.002
更新日期：2017-08-01 00:00:00
