Abstract:
:Melatonin is synthesized and secreted during the dark period of the light-dark cycle. Thus, melatonin has an obvious association with sleep, at least in diurnal animals. Rhythmic nocturnal melatonin secretion is directly generated by the circadian clock, located in mammals within the suprachiasmatic nuclei (SCN), and is entrained to a 24-h period by the light-dark cycle. The periodic secretion of melatonin may be used as a circadian mediator to any system than can "read" the message. In addition, direct effects of the hormone on the SCN could explain some of melatonin effects on the circadian system. Duration of melatonin nocturnal secretion is directly proportional to the length of the night and it has been demonstrated experimentally to be the critical parameter for photoperiod integration. The two main hypotheses to explain the action of melatonin are the duration hypothesis (supporting that night length is coded by the duration of the melatonin secretory phase) and the coincidence hypothesis (holding that physiological responses are linked to the existence of a diurnal rhythm in sensitivity to melatonin). The sites and mechanisms of action of melatonin for circadian and photoperiodic responses are far from being elucidated, but action through specific membrane receptor sites is well documented. In view of melatonin s lipophilic nature, interactions with specific intracellular proteins like calmodulin or tubulin, or with nuclear receptor sites, have also been considered, whereas the physiological significance of the documented antioxidant effect of melatonin remains to be settled. Melatonin seems to act as an "arm" of the circadian clock, giving a time-related signal to a number of body functions; one of these, the circadian organization of an organism's defence, is discussed in some detail as an example.
journal_name
Sleep Med Revjournal_title
Sleep medicine reviewsauthors
Cardinali DP,Pévet Pdoi
10.1016/s1087-0792(98)90020-xsubject
Has Abstractpub_date
1998-08-01 00:00:00pages
175-90issue
3eissn
1087-0792issn
1532-2955pii
S108707929890020Xjournal_volume
2pub_type
杂志文章abstract::Dopaminergic drugs have been widely used over the last decades for the treatment of restless legs syndrome (RLS)/Willis-Ekbom disease (WED). While the majority of studies show an initial improvement in symptoms, longer studies and clinical experience show that either treatment efficacy decreases with time, and/or augm...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2018.01.001
更新日期:2018-10-01 00:00:00
abstract::Large elastic arteries and smaller muscular conduit arteries become stiffer with ageing, a process that is accelerated in the presence of cardiovascular disease (CVD). In recent years, numerous techniques have been developed to measure arterial stiffness, either in single vessels or in entire muscular arterial trees. ...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2012.03.002
更新日期:2013-02-01 00:00:00
abstract::Based on electrophysiological, neurochemical, genetic and neuropharmacological approaches it is currently accepted that serotonin (5-HT) functions to promote waking (W) and to inhibit rapid-eye movement sleep (REMS). The serotonin-containing neurons of the dorsal raphe nucleus (DRN) provide part of the serotonergic in...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2009.10.003
更新日期:2010-10-01 00:00:00
abstract::In recent years, strong evidence has emerged suggesting that insufficient duration, quality, and/or timing of sleep are associated with cardiovascular disease (CVD), and various mechanisms for this association have been proposed. Such associations may be related to endophenotypic features of the sleep homeostat and th...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.05.004
更新日期:2017-06-01 00:00:00
abstract::Rhythmic movement disorder consists of repetitive stereotypic movements, such as head banging or body rocking, that recur every second or so and may last from a few minutes to hours, usually prior to sleep onset. This review of childhood rhythmic movement disorder highlights the lack of systematic research into core a...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.08.003
更新日期:2017-10-01 00:00:00
abstract::Women's sleep quality has been reported to change during pregnancy; prevalence estimates of poor sleep quality during pregnancy vary widely. To further understand the observed variation of findings, we conducted a meta-analysis to quantify the prevalence of poor sleep quality during pregnancy. Articles (N = 24) that r...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.smrv.2017.06.005
更新日期:2018-04-01 00:00:00
abstract::Patients with obstructive sleep apnoea (OSA) experience neuropsychological deficits falling broadly into the four areas of daytime sleepiness, cognitive deficits, reduced driving competence and impaired psychosocial well-being. Case-control studies of daytime function in OSA patients generally indicate moderate to sev...
journal_title:Sleep medicine reviews
pub_type: 杂志文章
doi:10.1016/s1087-0792(99)90014-x
更新日期:1999-03-01 00:00:00
abstract::Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is common during pregnancy, affecting approximately one in five pregnant women in Western countries. Many report moderate or severe symptoms and negative impact on sleep. There is very little information in the medical literature for practitioners on the manageme...
journal_title:Sleep medicine reviews
pub_type: 共识发展会议,杂志文章,实务指引,评审
doi:10.1016/j.smrv.2014.10.009
更新日期:2015-08-01 00:00:00
abstract::With this systematic review we aimed to determine the prevalence of obstructive sleep apnea (OSA) in adults in the general population and how it varied between population sub-groups. Twenty-four studies out of 3807 found by systematically searching PubMed and Embase databases were included in this review. Substantial ...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.07.002
更新日期:2017-08-01 00:00:00
abstract::Questionnaires are a useful and extensively used tool in clinical sleep medicine and in sleep research. The number of sleep questionnaires targeting the pediatric age range has tremendously increased in recent years, and with such explosion in the number of instruments, their heterogeneity has become all the more appa...
journal_title:Sleep medicine reviews
pub_type: 杂志文章
doi:10.1016/j.smrv.2010.06.003
更新日期:2011-02-01 00:00:00
abstract::Recent transcript profiling and microarray studies are beginning to unveil some of the mysteries of sleep. One of the most important clues has been the identification of the endoplasmic reticulum (ER) resident chaperone, immunoglobulin binding protein (BiP), that increases with sleep deprivation in all species studied...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2009.01.001
更新日期:2009-06-01 00:00:00
abstract::Sleep can improve the off-line memory consolidation of new items of declarative and non-declarative information in healthy subjects, whereas acute sleep loss, as well as sleep restriction and fragmentation, impair consolidation. This suggests that, by modifying the amount and/or architecture of sleep, chronic sleep di...
journal_title:Sleep medicine reviews
pub_type: 杂志文章
doi:10.1016/j.smrv.2012.01.004
更新日期:2013-04-01 00:00:00
abstract::This review summarises data gathered on the KC phenomenon over the past 70 yr. The following issues are discussed: definitions, morphology and topography of KC, the regular participation in NREM sleep, elicitability features of evoked KC, autonomic and motor concomitants, relationship of KC with information processing...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2005.04.003
更新日期:2005-10-01 00:00:00
abstract::The cardiovascular co-morbidities of obstructive sleep apnea (OSA) are similar to those of obesity. Cardiovascular co-morbidities often are the cause of adverse outcomes in overweight/obese OSA patients. Continuous positive airway pressure (CPAP) therapy resolves the symptoms of OSA, but may, or may not lead to improv...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.12.001
更新日期:2018-02-01 00:00:00
abstract::This review covers the literature on behavioural and cognitive-behavioural treatments for sleep disturbance in infants, pre-school, and school-age children. Treatment areas are dyssomnias (disorders of initiating, maintaining, or excessive sleep) and parasomnias (behaviours which occur predominantly during sleep). Int...
journal_title:Sleep medicine reviews
pub_type: 杂志文章
doi:10.1053/smrv.1999.0082
更新日期:1999-12-01 00:00:00
abstract::On-call work is becoming an increasingly common work pattern, yet the human impacts of this type of work are not well established. Given the likelihood of calls to occur outside regular work hours, it is important to consider the potential impact of working on-call on stress physiology and sleep. The aims of this revi...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.06.001
更新日期:2017-06-01 00:00:00
abstract::Sleep plays a vital role in physical and mental functioning. It is increasingly recognized that disturbed sleep is a highly prevalent and chronic condition that merits greater awareness due to the wide-ranging and serious repercussions associated with it. Nocturia is one of the causes of sleep disturbance and has been...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2010.03.002
更新日期:2011-04-01 00:00:00
abstract::Obstructive sleep apnea results from the combination of a structurally small upper airway combined with the loss of muscle tone during sleep. Most therapies aim to reduce apnea severity by increasing airway size and stability. Conceptually, upper airway surgery should be a highly effective method to treat obstructive ...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2008.07.010
更新日期:2008-12-01 00:00:00
abstract::There is considerable research evidence suggesting that sleep is biologically linked to mood disorders in adults. However, polysomographic and neuroendocrine studies in children and adolescents have not found consistent changes in sleep architecture paralleling adult major depression. This review provides a detailed d...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2004.09.006
更新日期:2005-04-01 00:00:00
abstract::Sleep staging is a vital process conducted in order to analyze polysomnographic data. To facilitate prompt interpretation of these recordings, many automatic sleep staging methods have been proposed. These methods rely on bio-signal recordings, which include electroencephalography, electrocardiography, electromyograph...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2020.101377
更新日期:2021-02-01 00:00:00
abstract::In addition to its role in vision, light exerts strong effects on behavior. Its powerful role in the modulation of mood is well established, yet remains poorly understood. Much research has focused on the effects of light on circadian rhythms and subsequent interaction with alertness and depression. The recent discove...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2011.09.002
更新日期:2012-10-01 00:00:00
abstract::Daytime sleepiness and sleep disordered breathing are increased in older compared to middle-aged adults. The cognitive and cardiovascular sequelae associated with obstructive sleep apnea (OSA) have significant implications for the older adult who may already be suffering from chronic illness. Most of the evidence supp...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2006.08.001
更新日期:2007-04-01 00:00:00
abstract::Sleep is important for the development of preterm infants. During sleep, neural connections are formed and the development of brain regions is triggered. In general, various rudimentary sleep states can be identified in the preterm infant, namely active sleep (AS), quiet sleep (QS) and intermediate sleep (IS). As the ...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2016.03.005
更新日期:2017-04-01 00:00:00
abstract::Recent evidence suggests that air pollution exposure may be a contributing risk factor for obstructive sleep apnea (OSA), however, current evidence is conflicting. This systematic review aims to determine the association between air pollution and OSA in the general population, and examine for potential effect modifica...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2020.101360
更新日期:2020-12-01 00:00:00
abstract::Despite advances in positive pressure therapy for obstructive sleep apnea, compliance continues to be a problem for many patients. Sleep apnea surgery is a viable option for patients who are intolerant of positive pressure therapy. This review will present the current state of art in sleep apnea surgery, including air...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2005.01.004
更新日期:2005-06-01 00:00:00
abstract::People with autism spectrum disorder (ASD) commonly experience other comorbidities. Studies indicate that between 50% and 83% of individuals with ASD have sleep problems or disorders. The most commonly reported sleep problems are: (a) insomnia symptoms including the inability to get to sleep or stay asleep; and (b) ci...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2020.101357
更新日期:2020-12-01 00:00:00
abstract::Activity-based sleep-wake monitoring or actigraphy has gained a central role as a sleep assessment tool in sleep medicine. It is used for sleep assessment in clinical sleep research, and as a diagnostic tool in sleep medicine. This update indicates that according to most studies, actigraphy has reasonable validity and...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2010.10.001
更新日期:2011-08-01 00:00:00
abstract::Polysomnographic studies have been performed to examine sleep abnormalities in posttraumatic stress disorder (PTSD), but clear associations between PTSD and sleep disturbances have not been established. A systematic review of the evidence examining the polysomnographic changes in PTSD patients compared with controls w...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,meta分析
doi:10.1016/j.smrv.2019.08.004
更新日期:2019-12-01 00:00:00
abstract::In this paper, we review the effects of nocturnal mechanical ventilation on sleep. Indeed, although non-invasive assisted ventilation during sleep has been applied extensively, the exact effects of this treatment on sleep quality have not been thoroughly studied. In patients with severe chronic obstructive pulmonary d...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1053/smrv.2001.0161
更新日期:2002-02-01 00:00:00
abstract::Exercise has promising effects on sleep disturbances and quality of life among cancer patients. Aerobic exercises (AE) and mind-body exercises (MBE) have different mechanisms for improving sleep, but whether they are effective remains unclear. This systematic review and meta-analysis is the first to examine the effect...
journal_title:Sleep medicine reviews
pub_type: 杂志文章,评审
doi:10.1016/j.smrv.2020.101334
更新日期:2020-10-01 00:00:00