Abstract：
:The cardiovascular co-morbidities of obstructive sleep apnea (OSA) are similar to those of obesity. Cardiovascular co-morbidities often are the cause of adverse outcomes in overweight/obese OSA patients. Continuous positive airway pressure (CPAP) therapy resolves the symptoms of OSA, but may, or may not lead to improvement of a given cardiovascular co-morbidity. The impact of CPAP on cardiovascular risk variables, adverse cardiovascular events in overweight/obese OSA patients has been evaluated primarily in prospective, uncontrolled cohort studies. These studies show improvement in myocardial and endothelial function, blood pressure, left ventricular performance and stroke survival. Randomized controlled studies (RCTs) examining the effect of weight management on cardiovascular risk factors and disease outcomes show that intentional weight loss leads to improvement in cardiovascular risk, hypertension, coronary artery disease, but not in stroke. Weight loss improves mortality in relatively healthy overweight/obese populations, but possibly not in all groups with cardiometabolic diseases. Clinicians caring for overweight/obese OSA patients should consider the advantages of incorporating weight management into their treatment programs for such patients.
journal_name
Sleep Med Revjournal_title
Sleep medicine reviewsauthors
Hudgel DWdoi
10.1016/j.smrv.2016.12.001subject
Has Abstractpub_date
2018-02-01 00:00:00pages
14-23eissn
1087-0792issn
1532-2955pii
S1087-0792(16)30151-4journal_volume
37pub_type
杂志文章,评审abstract：:This review summarises data gathered on the KC phenomenon over the past 70 yr. The following issues are discussed: definitions, morphology and topography of KC, the regular participation in NREM sleep, elicitability features of evoked KC, autonomic and motor concomitants, relationship of KC with information processing...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.04.003
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2010.03.002
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2020-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2010.08.001
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,meta分析
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2008.02.003
更新日期：2008-08-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2012.12.002
更新日期：2013-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2009.10.003
更新日期：2010-10-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.05.004
更新日期：2006-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.03.005
更新日期：2017-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2010.10.001
更新日期：2011-08-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2007.06.004
更新日期：2007-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1053/smrv.1999.0074
更新日期：2000-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 评论,杂志文章,评审
doi：10.1016/j.smrv.2008.04.008
更新日期：2008-10-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2009.07.005
更新日期：2010-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2013.03.002
更新日期：2014-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2008.07.010
更新日期：2008-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2013.07.004
更新日期：2014-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2018.05.004
更新日期：2018-12-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2019-10-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2017.04.002
更新日期：2018-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2009-06-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
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更新日期：2004-04-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章
doi：10.1053/smrv.2001.0177
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2012.03.002
更新日期：2013-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2020.101379
更新日期：2021-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/S1087-0792(03)00026-1
更新日期：2004-02-01 00:00:00
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journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2005.04.004
更新日期：2005-12-01 00:00:00
abstract：:Post-operative patients experience sleep disturbances. Animal studies demonstrate that general anaesthesia (GA) can disrupt circadian rhythms and cause changes in the molecular clock, indicating that anaesthesia contributes to post-operative circadian disruption. Here we review the effect of anaesthesia on the circadi...
journal_title：Sleep medicine reviews
pub_type： 杂志文章,评审
doi：10.1016/j.smrv.2016.12.002
更新日期：2018-02-01 00:00:00
