Mago Nashi and Tsunagi/Y14, respectively, regulate Drosophila germline stem cell differentiation and oocyte specification.

abstract：:The left-right body axis is coordinately aligned with the orthogonal dorsoventral and anterioposterior body axes. The developmental mechanisms that regulate axis coordination are unknown. Here it is shown that the cardiac left-right orientation in zebrafish (Danio rerio) is randomized in notochord-defective no tail an...

journal_title：Developmental biology

authors： Danos MC,Yost HJ

更新日期：1996-07-10 00:00:00

abstract：:The MSP domain is a conserved immunoglobulin-like structure that is important for C. elegans reproduction and human motor neuron survival. C. elegans MSPs are the most abundant proteins in sperm, where they function as intracellular cytoskeletal proteins and secreted hormones. Secreted MSPs bind to multiple receptors ...

journal_title：Developmental biology

authors： Yang Y,Han SM,Miller MA

更新日期：2010-06-01 00:00:00

abstract：:The ectoderm of early Xenopus gastrula is competent to become induced to neural tissue, but dorsal ectoderm is more neural competent than ventral ectoderm. It is a tenable, but as yet untested possibility that the higher neural competence of dorsal gastrula ectoderm is dependent on the presence of the dorsal mesoderm....

journal_title：Developmental biology

authors： Otte AP,Moon RT

更新日期：1992-07-01 00:00:00

abstract：:Chondrocytes were isolated from the auricular cartilage of rabbits, aged 1 week to 30 months, and grown in short-term cell culture. The cells from the 1-week animals were small, polygonal, and mononucleated, while the chondrocytes from the older animals were larger, rounded, and frequently binucleated. The synthesis o...

journal_title：Developmental biology

authors： Madsen K,Moskalewski S,von der Mark K,Friberg U

更新日期：1983-03-01 00:00:00

abstract：:The transcription factors, GATA4, 5 and 6, recognize the same DNA sequence and are all expressed in the developing myocardium. However, knockout studies in the mouse have indicated that none of them are absolutely required for the specification of the myocardium. Here we present evidence for redundancy in this family ...

journal_title：Developmental biology

authors： Peterkin T,Gibson A,Patient R

更新日期：2007-11-15 00:00:00

abstract：:During chick limb development the gap junction protein Connexin-43 (Cx43) is expressed in discrete spatially restricted domains in the apical ectodermal ridge (AER) and mesenchyme of the zone of polarising activity. Antisense oligonucleotides (ODNs) were used to investigate the role of Connexin-43 (Cx43) in the develo...

journal_title：Developmental biology

authors： Makarenkova H,Patel K

更新日期：1999-03-15 00:00:00

abstract：:Much progress has been made in elucidating the molecular networks required for specifying retinal cells, including photoreceptors, but the downstream mechanisms that maintain identity and regulate differentiation remain poorly understood. Here, we report that the transcription factor Glass has a dual role in establish...

journal_title：Developmental biology

authors： Liang X,Mahato S,Hemmerich C,Zelhof AC

更新日期：2016-06-01 00:00:00

abstract：:Sensory placodes are unique columnar epithelia with neurogenic potential that develop in the vertebrate head ectoderm next to the neural tube. They contribute to the paired sensory organs and the cranial sensory ganglia generating a wide variety of cell types ranging from lens fibres to sensory receptor cells and neur...

journal_title：Developmental biology

authors： Streit A

更新日期：2004-12-01 00:00:00

abstract：:The HNK-1 antibody recognizes a carbohydrate moiety that is shared by a family of cell adhesion molecules and is also present on the surface of migrating neural crest cells. Here, the effects of the HNK-1 antibody on neural crest cells were examined in vitro and in vivo. When the HNK-1 antibody was added to neural tub...

journal_title：Developmental biology

authors： Bronner-Fraser M

更新日期：1987-10-01 00:00:00

abstract：:Morphogenesis of the cartilaginous otic capsule is directed by interactions between the epithelial anlage of the membranous labyrinth (otocyst) and its associated periotic mesenchyme. Utilizing a developmental series of high-density (micromass) cultures of periotic mesenchyme to model capsule chondrogenesis, we have s...

journal_title：Developmental biology

authors： Frenz DA,Van De Water TR

更新日期：1991-03-01 00:00:00

abstract：:The notochord is the defining characteristic of the chordate embryo and plays critical roles as a signaling center and as the primitive skeleton. In this study we show that early notochord development in Xenopus embryos is regulated by apoptosis. We find apoptotic cells in the notochord beginning at the neural groove ...

journal_title：Developmental biology

authors： Malikova MA,Van Stry M,Symes K

更新日期：2007-11-15 00:00:00

abstract：:The vertebrate cranial base is a complex structure composed of bone, cartilage and other connective tissues underlying the brain; it is intimately connected with development of the face and cranial vault. Despite its central importance in craniofacial development, morphogenesis and tissue origins of the cranial base h...

journal_title：Developmental biology

authors： McBratney-Owen B,Iseki S,Bamforth SD,Olsen BR,Morriss-Kay GM

更新日期：2008-10-01 00:00:00

abstract：:Despite undergoing normal development and acquiring normal morphology and motility, mutations in spe-38 or trp-3/spe-41 cause identical phenotypes in Caenorhabditis elegans-mutant sperm fail to fertilize oocytes despite direct contact. SPE-38 is a novel, four-pass transmembrane protein and TRP-3/SPE-41 is a Ca(2+)-per...

journal_title：Developmental biology

authors： Singaravelu G,Chatterjee I,Rahimi S,Druzhinina MK,Kang L,Xu XZ,Singson A

更新日期：2012-05-15 00:00:00

abstract：:Differences are demonstrated in the chondrogenic potential of cells derived from the distal and proximal halves of chick wing buds from as early as stage 23, prior to the appearance of overt cartilage differentiation. In high cell density cultures, cells obtained from the distal portions of stage 23 or 24 limb buds ar...

journal_title：Developmental biology

authors： Swalla BJ,Owens EM,Linsenmayer TF,Solursh M

更新日期：1983-05-01 00:00:00

abstract：:Cell adhesion molecules (CAMs) perform numerous functions during neural development. An individual CAM can play different roles during each stage of neuronal differentiation; however, little is known about how such functional switching is accomplished. Here we show that Drosophila N-cadherin (CadN) is required at mult...

journal_title：Developmental biology

authors： Kurusu M,Katsuki T,Zinn K,Suzuki E

更新日期：2012-06-15 00:00:00

abstract：:The fertilization potential in Phallusia mammillata consisted of an initial rapid depolarization. This initial sperm-triggered depolarization was followed by a phase of membrane depolarization which was of either long or short duration, depending on the eggs. When of long duration, the phase of membrane depolarization...

journal_title：Developmental biology

authors： Goudeau H,Goudeau M,Guibourt N

更新日期：1992-10-01 00:00:00

abstract：:Trichosia pubescens larvae were ligated at different prepupal developmental stages in order to investigate whether ecdysterone acts just as a trigger or whether its presence in the hemolymph is constantly necessary for the induction of the late puffs, in particular the DNA puffs. The larvae were ligated in the middle ...

journal_title：Developmental biology

authors： Amabis DC,Amabis JM

更新日期：1984-03-01 00:00:00

abstract：:To form a gonad, germ cells (GCs) and somatic gonadal precursor cells (SGPs) must migrate to the correct location in the developing embryo and establish the cell-cell interactions necessary to create proper gonad architecture. During gonad morphogenesis, SGPs send out cellular extensions to ensheath the individual GCs...

journal_title：Developmental biology

authors： Jemc JC,Milutinovich AB,Weyers JJ,Takeda Y,Van Doren M

更新日期：2012-07-15 00:00:00

abstract：:Mf1, which encodes a winged-helix/forkhead transcription factor, is the murine homolog of human FKHL7, mutated in individuals with autosomal dominant inherited dysgenesis of the anterior segment of the eye (Axenfeld-Reiger anomaly). Mouse embryos homozygous for null mutations in Mf1 (Mf1(lacZ) and Mf1(ch)) show severe...

journal_title：Developmental biology

authors： Kidson SH,Kume T,Deng K,Winfrey V,Hogan BL

更新日期：1999-07-15 00:00:00

abstract：:Extraocular muscles (EOM) represent a unique muscle group that controls eye movements and originates from head mesoderm, while the more typically studied body and limb muscles are somite-derived. Aiming to investigate myogenic progenitors (satellite cells) in EOM versus limb and diaphragm of adult mice, we have been u...

journal_title：Developmental biology

authors： Stuelsatz P,Shearer A,Yablonka-Reuveni Z

更新日期：2014-01-15 00:00:00

abstract：:To investigate the mechanism by which the hormone 17 alpha,20 beta-dihydroxy-4-pregnen-3-one(17 alpha,20 beta-DP) acts on a receptor on the external surface of rainbow trout oocytes to induce maturation, the interaction between 17 alpha,20 beta-DP receptors and G-proteins was examined. Pertussis toxin (PT) catalyzed t...

journal_title：Developmental biology

authors： Yoshikuni M,Nagahama Y

更新日期：1994-12-01 00:00:00

abstract：:Mesenchymal-epithelial interactions are an important source of information for pattern formation during organogenesis. In the developing excretory system, one of the secreted mesenchymal factors thought to play a critical role in patterning the growth and branching of the epithelial ureteric bud is GDNF. We have teste...

journal_title：Developmental biology

authors： Shakya R,Jho EH,Kotka P,Wu Z,Kholodilov N,Burke R,D'Agati V,Costantini F

更新日期：2005-07-01 00:00:00

abstract：:The Ca2+ oscillations initiated by the fertilizing sperm (but terminating concomitant with pronucleus formation) apparently ensure that the events constituting egg activation occur in the correct temporal order; early events (e.g., cortical granule exocytosis) require fewer oscillations than later events (e.g., recrui...

journal_title：Developmental biology

authors： Ozil JP,Banrezes B,Tóth S,Pan H,Schultz RM

更新日期：2006-12-15 00:00:00

abstract：:Type II collagen is a major component of cartilage extracellular matrix. Differentiation of mesenchyme into cartilage involves the cessation of type I collagen synthesis and the onset of type II collagen synthesis. Solution hybridization of mRNA isolated from chick limb buds with a cDNA probe to type II collagen mRNA ...

journal_title：Developmental biology

authors： Swalla BJ,Upholt WB,Solursh M

更新日期：1988-01-01 00:00:00

abstract：:The lateral line system displays highly divergent patterns in adult teleost fish. The mechanisms underlying this variability are poorly understood. Here, we demonstrate that the lateral line mechanoreceptor, the neuromast, gives rise to a series of accessory neuromasts by a serial budding process during postembryonic ...

journal_title：Developmental biology

authors： Wada H,Ghysen A,Satou C,Higashijima S,Kawakami K,Hamaguchi S,Sakaizumi M

更新日期：2010-04-15 00:00:00

abstract：:In vertebrates, the segmented somites, which are the medial-most component in the paraxial mesoderm, are the entity giving rise to the axial bones and skeletal muscles. We previously demonstrated that the mechanism that distinguishes the somite from the more lateral mesoderm (lateral plate) involves different levels o...

journal_title：Developmental biology

authors： Tonegawa A,Takahashi Y

更新日期：1998-10-15 00:00:00

abstract：:Catecholaminergic cells are transiently present during development of the fetal murine bowel. These transient catecholaminergic (TC) cells appear at Day E10, but by Day E13 can no longer be detected. In order to evaluate the hypothesis that these cells are the precursors of enteric neurons, we investigated the possibi...

journal_title：Developmental biology

authors： Baetge G,Gershon MD

更新日期：1989-03-01 00:00:00

abstract：:We report here the identification and characterization of a novel gene, T1 alpha, expressed in high abundance in adult rat lung, fetal lung, and early fetal brain. T1 alpha was identified by a monoclonal antibody previously shown to be specific for an antigen expressed by alveolar epithelial type I cells. The cDNA for...

journal_title：Developmental biology

authors： Rishi AK,Joyce-Brady M,Fisher J,Dobbs LG,Floros J,VanderSpek J,Brody JS,Williams MC

更新日期：1995-01-01 00:00:00

abstract：:Polyspermic Xenopus laevis eggs can be identified easily because of regions of pigment accumulation and white stripes, which arise by a nocodazole-sensitive process. Eggs containing up to four sperm are capable of forming a single embryonic axis. Dispermic eggs display two regions of pigment accumulation, one around e...

journal_title：Developmental biology

authors： Render JA,Elinson RP

更新日期：1986-06-01 00:00:00

abstract：:Completion of cytokinesis, abscission, has been studied little despite the intensive studies of the onset and contractile mechanism of the earlier phases of division. It has been well documented that microtubule (MT) disruption before furrow stimulation prevents furrowing, while MT disruption after furrow stimulation ...

journal_title：Developmental biology

authors： Larkin K,Danilchik MV

更新日期：1999-10-01 00:00:00