Abstract:
:Since the advent of single particle/molecule microscopies, researchers have applied these techniques to understanding the fluid membranes of cells. By observing diffusion of membrane proteins and lipids in live cell membranes of eukaryotic cells, it has been found that membranes contain a mosaic of fluid compartments. Such structure may be instrumental in understanding key characteristics of the membrane. Recent single molecule observations on prokaryotic cell membranes will also be discussed.
journal_name
Biopolymersjournal_title
Biopolymersauthors
Ritchie K,Spector Jdoi
10.1002/bip.20801subject
Has Abstractpub_date
2007-10-05 00:00:00pages
95-101issue
2-3eissn
0006-3525issn
1097-0282journal_volume
87pub_type
杂志文章,评审相关文献
BIOPOLYMERS文献大全abstract::The conformation and intermolecular association of [D-Hyi2, L-Hyi4] meso-valinomycin [cyclo[-D-Val-D-Hyi-L-Val-L-Hyi-(D-Val-L-Hyi-L-Val-D-+ ++Hyi)2-], C60H102N6O18] in a crystal form obtained from ethanol solution has been determined by x-ray crystallography. Two depsipeptides and one ethanol molecule per asymmetric u...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0282(199711)42:6<645::AID-BIP3>
更新日期:1997-11-01 00:00:00
abstract::Nodal, a member of the transforming growth factor-β superfamily, is a potent embryonic morphogen also implicated in tumor progression. Up to date structural information on the interaction of Nodal with its molecular partners are unknown. To deepen our understanding about mechanisms underlying both embryonic developmen...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.21517
更新日期:2010-11-01 00:00:00
abstract::The second derivative FTIR study of heat-induced and pressure-assisted cold-induced changes in the secondary structure of bovine alpha-lactalbumin was carried out for native holoprotein and calcium ion depleted apoprotein. The secondary structure and compactness of alpha-lactalbumin were examined in a temperature rang...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/1097-0282(2001)62:1<29::AID-BIP50>3.0.CO;2
更新日期:2001-01-01 00:00:00
abstract::Chiral interaction of helical peptide with chiral molecule, and concomitant induction in its helix sense have been demonstrated in optically inactive nonapeptide (1) possessing Gly at its N-terminus: H-Gly-(Delta(Z)Phe-Aib)(4)-OCH(3) (1: Delta(Z)Phe = Z-dehydrophenylalanine; Aib = alpha-aminoisobutyric acid). Spectros...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.20557
更新日期:2006-11-01 00:00:00
abstract::The results are presented for the deconvolution of IR spectra of disaccharides and polysaccharides with alpha and beta configurations of the 1 --> 4 glycosidic linkage (maltose, cellobiose, amylose, and cellulose), as well as of their corresponding monosaccharides (alpha- and beta-D-glucose) in the 1200-920 cm(-1) fre...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/1097-0282(2000)57:4<257::AID-BIP7>3.0.CO;2
更新日期:2000-01-01 00:00:00
abstract::The shed epidermis (molt) of snakes comprises four distinct layers. The upper two layers, here considered as beta-layer, contain essentially beta-keratin. The following layer, known as mesos-layer, is similar to the human stratum corneum, and is formed by thin cells surrounded by intercellular lipids. The latter layer...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.21184
更新日期:2009-12-01 00:00:00
abstract::Combinatorial library composed of rigid rod-like peptides with a triple-helical scaffold was constructed. The component peptides were designed to have various combinations of basic and neutral (or hydrophobic) amino acid residues based on collagen-like (Gly-Pro-Yaa)-repeating sequences, inspired from the basic and amp...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.22791
更新日期:2016-11-04 00:00:00
abstract::Individual ethidium-stained DNA molecules, embedded in an agarose gel made with electrophoresis buffer (0.05 molar salt), are observed using a fluorescence microscope. In the first experiment, open circular 66 kilobase pair (kbp) plasmids, immobilized by agarose fibers threaded through their centers, display entropic ...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360290807
更新日期:1990-07-01 00:00:00
abstract::CD experiments are reported for several coiled-coil species in the tyrosine/disulfide (approximately 250-350-nm) region. Intact noncross-linked tropomyosin (approximately 3 degrees C) shows a negative nonsymmetric band maximal at 280 nm. This spectrum is the sum over six tyrosines/chain, and has conformational signifi...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360280909
更新日期:1989-09-01 00:00:00
abstract::A topochemical model to explain the biological activity of dendrotoxin-I (DTX-I), a potent blocker for potassium channels, was developed by searching common spatial arrangements of functionally important residues between DTX-I, alpha-dendrotoxin, dendrotoxin-K, BgK, ShK, and charybdotoxin. The first three are structur...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0282(200007)54:1<44::AID-BIP50>
更新日期:2000-07-01 00:00:00
abstract::The Electrostatically Driven Monte Carlo (EDMC) method was applied in a study of a decamer of glycine whose conformational behavior is described by the Empirical Conformational Energy Program for Peptides (ECEPP/2) potential energy model. When free neutral end groups were used, it was found that conformations that wer...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360310306
更新日期:1991-02-15 00:00:00
abstract::The rheological characteristics of gastric and duodenal mucin solutions, the building blocks of the mucus layer that covers the epithelia of the two organs, were investigated using particle tracking microrheology. We used biochemically well characterized purified porcine mucins (MUC5AC and MUC2) as models for human mu...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.22372
更新日期:2014-04-01 00:00:00
abstract::A novel nucleic acid model using peptide ribonucleic acid (PRNA), which contains 5'-amino-5'-deoxypyrimidine ribonucleoside as a recognition site for nucleic acids, has been designed, synthesized and applied to the external reversible control of recognition behavior of the complementary polynucleotide through the orie...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.10563
更新日期:2004-01-01 00:00:00
abstract::Recent results from molecular dynamics (MD) simulations on hydration of DNA with respect to conformation are reviewed and compared with experimental data. MD simulations of explicit solvent around DNA can now give a detailed model of DNA that not only matches well with the experimental data but provides additional ins...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0282(1998)48:4<199::AID-BIP2>3.
更新日期:1998-01-01 00:00:00
abstract::The spectroscopic properties of syringomycin E, an antibiotic lipodepsinonapeptide associated with pathological states in plants, have been investigated by uv absorbance and CD spectroscopies, and by the synthesis of relevant model compounds. Initial studies [E. Vaillo, A. Ballio, P. L. Luisi, and R. M. Thomas (1990) ...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360321006
更新日期:1992-10-01 00:00:00
abstract::Interactions between biological macromolecules have characteristic values of affinity and specificity that are set according to the biological function that is served by the interaction in the organism. Here we examine the molecular mechanisms that are used to achieve the required values of affinity and specificity in...
journal_title:Biopolymers
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0282(1997)44:2<181::AID-BIP5>3.
更新日期:1997-01-01 00:00:00
abstract::Amphipathic peptides composed of alternating polar and nonpolar residues have a strong tendency to self-assemble into one-dimensional, amyloid-like fibril structures. Fibrils derived from peptides of general (XZXZ)(n) sequence in which X is hydrophobic and Z is hydrophilic adopt a putative β-sheet bilayer. The bilayer...
journal_title:Biopolymers
pub_type: 杂志文章,评审
doi:10.1002/bip.22058
更新日期:2012-01-01 00:00:00
abstract::We have previously proposed a model for the delta-opioid receptor binding conformation of the high affinity tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13) based on experimental and theoretical conformational analysis of this peptide and a correlation of conformational preferences of further conformationally restricted...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/(sici)1097-0282(199609)39:3<287::aid-bip2>
更新日期:1996-09-01 00:00:00
abstract::Elastin-like polypeptide (ELP) fusions have been designed to allow large-scale, nonchromatographic purification of many soluble proteins by using the inverse transition cycling (ITC) method; however, the sensitivity of the aqueous lower critical solubility phase transition temperature (T(t)) of ELPs to the addition of...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.22137
更新日期:2013-01-01 00:00:00
abstract::The fusion of two stable bilayers likely proceeds through intermediates in which the membrane acquires curvature. The insertion of peptides into the membrane will affect its curvature tendency. Studies with a number of small viral fusion peptides indicate that these peptides promote negative curvature at low concentra...
journal_title:Biopolymers
pub_type: 杂志文章,评审
doi:10.1002/1097-0282(2000)55:5<358::AID-BIP1009>3.0.C
更新日期:2000-01-01 00:00:00
abstract::The structural evolution of regenerated Bombyx mori silk fibroin during shearing with a Couette cell has been studied in situ by synchrotron radiation small- and wide-angle x-ray scattering techniques. An elongation of fibroin molecules was observed with increasing shear rate, followed by an aggregation phase. The agg...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.20083
更新日期:2004-07-01 00:00:00
abstract::An electron paramagnetic resonance (EPR) study was performed for potato and wheat starch containing Cu2+ ions as a paramagnetic probe. Distribution of water in the starch granules as well as the interactions between the copper and starch matrix of different crystalline structures were determined. EPR spectra of the na...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.20504
更新日期:2006-08-15 00:00:00
abstract::Disintegrins, small molecular weight proteins contained in the venom of vipers and rattlesnakes, are high-affinity and selectivity integrin antagonists. Disintegrins inhibitory epitope mainly consists in a tripeptide sequence localized in a mobile loop protruding from the protein core. RTS and/or KTS tripeptide charac...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.22578
更新日期:2015-03-01 00:00:00
abstract::Amyloid fibrils are considered to play causal roles in the pathogenesis of amyloid-related degenerative diseases such as Alzheimer's disease, type II diabetes mellitus, the transmissible spongiform encephalopathies, and prion disease. The mechanism of fibril formation is still hotly debated and remains an important op...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.21405
更新日期:2010-06-01 00:00:00
abstract::A new representation of protein sequence is devoted in this paper, in which each protein can be represented by a 20-dimensional (20D) vector of unit length. Inspired by the principle of superposition of state in quantum mechanics, the squares of the 20 components of the vector correspond to the amino acid composition....
journal_title:Biopolymers
pub_type:
doi:10.1002/1097-0282(20010415)58:5<491::AID-BIP1024>3
更新日期:2001-04-15 00:00:00
abstract::TC5b is a 20 residue polypeptide notable for its compact tertiary structure, a rarity for a short peptide. This structure is due to the "Trp-cage" motif, an association of aromatic, Pro, and Gly residues. The structure of TC5b has been fully characterized by NMR and electronic circular dichroism (ECD) studies, but has...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.20709
更新日期:2007-01-01 00:00:00
abstract::Myelopeptides (MPs) are bioregulatory mediators of bone marrow origin. Several individual MPs have been isolated from the supernatant of porcine bone marrow cell culture by successive solid phase extraction and reversed-phase high performance liquid chromatography. Two of them, MP-1 (Phe-Leu-Gly-Phe-Pro-Thr) and MP-2 ...
journal_title:Biopolymers
pub_type: 杂志文章,评审
doi:10.1002/(SICI)1097-0282(1997)43:2<139::AID-BIP7>3.
更新日期:1997-01-01 00:00:00
abstract::A series of cyclic retro-inverso dipeptides--2-[(4-hydroxy)benzyl]-5-benzyl-4,6(1H,2H,3H,5H)-pyrimidinedi one (c[mPhe-gTyr]), 2-benzyl-5-[(4-hydroxy)benzyl]-4,6(1H,2H,3H,5H)-pyrimidinedione (c[mTyr-gPhe]), and 2-benzyl-5-amino-5-[(4-hydroxy)benzyl]-4,6(1H,2H,3H,5H)-pyrimidinedione (c[(alpha-amino)mTyr-gPhe])--were syn...
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360311307
更新日期:1991-11-01 00:00:00
abstract::We analyzed the CD and uv absorption spectra of 5S RNA from Escherichia coli using the method developed in the preceding paper. The analysis of spectra of 5S RNA at 20 degrees C in 0.1M NaClO4, 2.5 mM Na+ (phosphate), pH 7.0, and 0.5 mM MgSO4 gave 7 +/- 3.6 A.U base pairs, 25 +/- 3.6 G.C base pairs, and 7.5 +/- 3.6 G....
journal_title:Biopolymers
pub_type: 杂志文章
doi:10.1002/bip.360310404
更新日期:1991-03-01 00:00:00
abstract::Host defense peptides are conserved components of innate immune response present among all classes of life. These peptides are potent, broad spectrum antimicrobial agents with potential as novel therapeutic compounds. Also, the ability of host defense peptides to modulate immunity is an emerging therapeutic concept si...
journal_title:Biopolymers
pub_type: 杂志文章,评审
doi:10.1002/bip.22076
更新日期:2012-01-01 00:00:00