Percutaneous ultrasound-guided radiofrequency ablation of hepatocellular carcinoma with artificially induced pleural effusion and ascites.

Abstract:

BACKGROUND:Ultrasound-guided procedures are sometimes of limited use because the tumor is located under the diaphragm or near the surface of the liver. We investigated the safety and efficacy of radiofrequency ablation (RFA) with artificial pleural effusion and/or artificial ascites. METHODS:Between January 2002 and May 2006, 43 lesions in 36 patients with hepatocellular carcinoma (HCC) were treated by RFA with artificial pleural effusion and/or artificial ascites. RESULTS:Artificial pleural effusion allowed visualization of the whole tumor for 36 (83.7%) of the 43 lesions that were otherwise not detectable or poorly visible. Artificial ascites was also helpful in visualizing whole tumors that could not be visualized with only artificial pleural effusion. In all lesions, artificial pleural effusion and/or artificial ascites were helpful in performing percutaneous RFA. Artificial ascites was useful for creating a space between the liver's surface and the skin or diaphragm to avoid burns. Adverse effects after the induction of artificial pleural effusion included pneumonia in one patient and temporary atelectasis in another patient. Severe side effects were not observed. Complete necrosis after RFA was obtained in 43 (100%) of the 43 lesions. During a mean follow-up period of 31.8 +/- 5.8 months, local recurrence at the ablation site was found in none of the 43 lesions. CONCLUSIONS:Percutaneous RFA with artificial pleural effusion and/or artificial ascites was a safe and useful treatment that resulted in good local control of HCC.

journal_name

J Gastroenterol

authors

Uehara T,Hirooka M,Ishida K,Hiraoka A,Kumagi T,Kisaka Y,Hiasa Y,Onji M

doi

10.1007/s00535-006-1949-0

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

306-11

issue

4

eissn

0944-1174

issn

1435-5922

journal_volume

42

pub_type

杂志文章
  • Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.

    abstract:BACKGROUND:Abrogating tolerance is a critical step in the pathogenesis of Crohn's disease (CD). T cell-anergy is one of the main mechanisms of tolerance and is regulated by the gene related to anergy in lymphocytes (GRAIL). This study investigated the expressions and regulation of GRAIL in CD and murine colitis models....

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0923-x

    authors: Mukai A,Iijima H,Hiyama S,Fujii H,Shinzaki S,Inoue T,Shiraishi E,Kawai S,Araki M,Hayashi Y,Kondo J,Mizushima T,Kanto T,Egawa S,Nishida T,Tsujii M,Takehara T

    更新日期:2014-12-01 00:00:00

  • Effectiveness of endoscopic biliary drainage for unresectable hepatocellular carcinoma associated with obstructive jaundice.

    abstract::Endoscopic biliary drainage (EBD) for unresectable hepatocellular carcinoma (HCC) associated with obstructive jaundice remains controversial because of the short survival of these patients. To evaluate the effectiveness of this procedure, we retrospectively studied 18 patients who had unresectable HCC with obstructive...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350170125

    authors: Matsueda K,Yamamoto H,Umeoka F,Ueki T,Matsumura T,Tezen T,Doi I

    更新日期:2001-03-01 00:00:00

  • Serum leptin level can be a negative marker of hepatocyte damage in nonalcoholic fatty liver.

    abstract:BACKGROUND:The aim of this study was to determine whether leptin and insulin resistance (IR) showed differences between steatotic patients with and without elevated serum transaminases. METHODS:The study included 32 patients with fatty liver and high serum transaminase level (group I), 31 patients with fatty liver and...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-002-1084-5

    authors: Serin E,Ozer B,Gümürdülü Y,Kayaselçuk F,Kul K,Boyacioğlu S

    更新日期:2003-01-01 00:00:00

  • Mortality rate of patients with asymptomatic primary biliary cirrhosis diagnosed at age 55 years or older is similar to that of the general population.

    abstract:PURPOSE:Recent routine testing for liver function and anti-mitochondrial antibodies has increased the number of newly diagnosed patients with primary biliary cirrhosis (PBC). This study investigated the prognosis of asymptomatic PBC patients, focusing on age difference, to clarify its effect on the prognosis of PBC pat...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-009-0090-2

    authors: Kubota J,Ikeda F,Terada R,Kobashi H,Fujioka S,Okamoto R,Baba S,Morimoto Y,Ando M,Makino Y,Taniguchi H,Yasunaka T,Miyake Y,Iwasaki Y,Yamamoto K

    更新日期:2009-01-01 00:00:00

  • Elevation of interleukin 6 levels in patients with chronic hepatitis due to hepatitis C virus.

    abstract::Interleukin 6 (IL-6) is a pleiotropic cytokine produced by a wide variety of lymphoid and non-lymphoid tissues. We studied the relationship between IL-6 and the liver in an attempt to elucidate this cytokine's role in hepatitis C-induced liver inflammation. We investigated the behavior of serum IL-6 in 25 patients wit...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF02936370

    authors: Malaguarnera M,Di Fazio I,Romeo MA,Restuccia S,Laurino A,Trovato BA

    更新日期:1997-04-01 00:00:00

  • Images of Sonazoid-enhanced ultrasonography in multistep hepatocarcinogenesis: comparison with Gd-EOB-DTPA-enhanced MRI.

    abstract:BACKGROUND:Little is known about the difference in enhancement patterns of hepatocellular carcinoma (HCC) during multistep hepatocarcinogenesis between the post-vascular phase of Sonazoid-enhanced ultrasonography (SEUS) and hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine (Gd-EOB-DTPA)-enhanced MRI, as...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0859-1

    authors: Ohama H,Imai Y,Nakashima O,Kogita S,Takamura M,Hori M,Seki Y,Sawai Y,Igura T,Fukuda K,Makino Y,Morimoto O,Ohsawa M,Sakamoto M,Murakami T

    更新日期:2014-06-01 00:00:00

  • Characterization of polyethylene glycol-grafted polyethylenimine and superparamagnetic iron oxide nanoparticles (PEG-g-PEI-SPION) as an MRI-visible vector for siRNA delivery in gastric cancer in vitro and in vivo.

    abstract:BACKGROUND:Gene therapy is a promising therapeutic method but is severely hampered due to its lack of an ideal delivery system. Therefore, in this study, a nonviral and magnetic resonance imaging (MRI) visible vector, polyethylene glycol-grafted polyethylenimine and superparamagnetic iron oxide nanoparticles (PEG-g-PEI...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0713-x

    authors: Chen Y,Lian G,Liao C,Wang W,Zeng L,Qian C,Huang K,Shuai X

    更新日期:2013-07-01 00:00:00

  • Direct dissolution of gallstones with methyl tert-butyl ether (MTBE) via endoscopic transpapillary catheterization in the gallbladder (ETCG).

    abstract::In a pilot study of direct dissolution therapy of gallstones with methyl tert-butyl ether (MTBE), endoscopic transpapillary catheterization in the gallbladder (ETCG) was performed. Complete dissolution was seen in 8 out of 12 (66%) patients and partial dissolution was seen in 2 (16%) patients. In one of the 8 complete...

    journal_title:Journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1007/BF02361248

    authors: Uchida N,Nakatsu T,Hirabayashi S,Minami A,Fukuma H,Ezaki T,Morshed SA,Fuke C,Ameno K,Ijiri I

    更新日期:1994-08-01 00:00:00

  • Intestinal microflora as a therapeutic target in inflammatory bowel disease.

    abstract::Although the causes of inflammatory bowel disease (IBD) remain incompletely understood, increasing evidence implicates intestinal microflora in the pathogenesis of these disorders. Alteration of intestinal flora therefore may offer a plausible therapeutic approach. Although recent data support a potential therapeutic ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/BF03326418

    authors: Mitsuyama K,Toyonaga A,Sata M

    更新日期:2002-11-01 00:00:00

  • Importance of medullary thyrotropin-releasing hormone in brain-gut circuits regulating gastric integrity: preclinical studies.

    abstract::Cold restraint stress (CRS) induced vagal-dependent corpus mucosal erosions with hemorrhage in rats. Aggressive factors such as gastric acid, pepsin, and high-amplitude contractions have been reported to be responsible for inducing the formation of gastric lesions. Thyrotropin-releasing hormone (TRH) microinjected int...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/BF03326431

    authors: Kaneko H,Taché Y,Kusugami K

    更新日期:2002-11-01 00:00:00

  • Relationship between progression of gastric mucosal atrophy and Helicobacter pylori infection: retrospective long-term endoscopic follow-up study.

    abstract::A retrospective long-term endoscopic follow-up study was designed to examine atrophic changes in the gastric mucosa over time in Helicobacter pylori-positive patients. Over a period of 8-17 years (mean, 13.4 years) 22 subjects (5 men, 17 women, mean age, 55 years) without localized gastroduodenal lesions underwent ser...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF01213291

    authors: Sakaki N,Arakawa T,Katou H,Momma K,Egawa N,Kamisawa T,Yamada Y,Tu Y,Ishikawa C,Ishiwata J

    更新日期:1997-02-01 00:00:00

  • Fecal calprotectin: its scope and utility in the management of inflammatory bowel disease.

    abstract::Gastrointestinal symptoms such as abdominal pain, dyspepsia, and diarrhea are relatively nonspecific and a common cause for seeking medical attention. To date, it is challenging for physicians to differentiate between functional and organic gastrointestinal conditions and it involves the use of serological and endosco...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s00535-016-1182-4

    authors: Ikhtaire S,Shajib MS,Reinisch W,Khan WI

    更新日期:2016-05-01 00:00:00

  • Clinical utility of grading criteria for submucosal invasion in the prognosis of T1 colorectal carcinomas.

    abstract:BACKGROUND:The clinical utility of relative and absolute grading criteria for submucosal invasion in T1 colorectal carcinomas has been controversial. METHODS:In 51 T1 colorectal carcinomas, depth of submucosal invasion was graded either according to a modified Haggitt's classification (a relative criterion) or by dire...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350300004

    authors: Masaki T,Sugiyama M,Matsuoka H,Abe N,Izumisato Y,Goto A,Sakamoto A,Atomi Y

    更新日期:2003-01-01 00:00:00

  • Anemia in patients with colorectal cancer.

    abstract::Although anemia is one of the signs of colorectal cancer, the relationships between histological findings and hematological findings other than hemoglobin level have not been adequately investigated. We investigated the relationship between hematological findings, serum iron, and histological findings in 358 patients ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050120

    authors: Sadahiro S,Suzuki T,Tokunaga N,Mukai M,Tajima T,Makuuchi H,Saito T

    更新日期:1998-08-01 00:00:00

  • Secondary prevention for hepatocellular carcinoma in patients with chronic hepatitis B: are all the nucleos(t)ide analogues the same?

    abstract::Reducing the incidence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB) is the key ultimate goal set in essentially all treatment guidelines. There has been solid evidence supporting the relationship between serum hepatitis B virus (HBV) DNA level and risk of HCC. Antiviral treatment with o...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s00535-020-01726-3

    authors: Yip TC,Lai JC,Wong GL

    更新日期:2020-11-01 00:00:00

  • Analysis of 6381 hepatocellular carcinoma patients in southern Taiwan: prognostic features, treatment outcome, and survival.

    abstract:BACKGROUND:This hospital-based analysis was conducted to identify prognostic factors of hepatocellular carcinoma (HCC) in a hepatitis B virus endemic area. METHODS:A total of 6381 HCC cases, diagnosed from 1986 to 2002, were enrolled, and 2890 (42.3%) of them were not treated. Survival rates were analyzed by correlati...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-007-2134-9

    authors: Changchien CS,Chen CL,Yen YH,Wang JH,Hu TH,Lee CM,Wang CC,Cheng YF,Huang YJ,Lin CY,Lu SN

    更新日期:2008-01-01 00:00:00

  • Correction to: Retinoic acid receptor γ activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium.

    abstract::In the original publication of the article, the following errors were noted and corrected in this correction. ...

    journal_title:Journal of gastroenterology

    pub_type: 已发布勘误

    doi:10.1007/s00535-020-01718-3

    authors: Koterazawa Y,Koyanagi-Aoi M,Uehara K,Kakeji Y,Aoi T

    更新日期:2020-10-01 00:00:00

  • Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaborative study.

    abstract:BACKGROUND:Depth of submucosal invasion (SM depth) in submucosal invasive colorectal carcinoma (SICC) is considered an important predictive factor for lymph node metastasis. However, no nationwide reports have clarified the relationship between SM depth and rate of lymph node metastasis. Our aim was to investigate the ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00535-004-1339-4

    authors: Kitajima K,Fujimori T,Fujii S,Takeda J,Ohkura Y,Kawamata H,Kumamoto T,Ishiguro S,Kato Y,Shimoda T,Iwashita A,Ajioka Y,Watanabe H,Watanabe T,Muto T,Nagasako K

    更新日期:2004-06-01 00:00:00

  • Nonrotation of the midgut with appendiceal mucocele in an adult.

    abstract::Nonrotation of the midgut in adults and appendiceal mucocele are both rare pathological conditions. We report here the first case of nonrotation of the midgut associated with appendiceal mucocele. The patient was a 51-year-old man admitted to hospital with ileus. An upper gastrointestinal series and a barium enema rev...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350170153

    authors: Kawashima K,Ishihara S,Amano K,Hirakawa K,Adachi K,Fukuda R,Sumi S,Watanabe M,Kinoshita Y

    更新日期:2001-01-01 00:00:00

  • Hepatic steatosis, carotid atherosclerosis and metabolic syndrome: the STEATO Study.

    abstract:PURPOSE:Hepatic steatosis is frequently observed in subjects with metabolic syndrome (MS). In type 2 diabetics, it is independently associated with cardiovascular diseases. In order to confirm and extend this finding, a large group of patients with risk factors for atherosclerosis was studied. METHODS:Carotid atherosc...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-009-0125-8

    authors: Carallo C,Mancuso G,Mauro G,Laghi F,Madafferi B,Irace C,Gnasso A,Scavelli F,Dell'Aquila F,Bartone M,Gullo F,Ferraro M,Spagnuolo V,Belmonte M,Ferrara A,Silvano Rotondaro A,Brandolino N,Parasporo F,Scopelliti F

    更新日期:2009-01-01 00:00:00

  • Efficacy of prolonged interferon therapy for patients with chronic hepatitis C with HCV-genotype 1b and high virus load.

    abstract:BACKGROUND:In patients with hepatitis C virus (HCV)-genotype 1b and a high virus load, of more than 1 Meq/ml by the DNA probe assay, the clearance of HCV-RNA was achieved in only 10% with a 6-month interferon (IFN) course. We therefore assessed the efficacy of prolonged IFN therapy in patients with HCV-genotype 1b and ...

    journal_title:Journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/s005350300026

    authors: Arase Y,Ikeda K,Tsubota A,Suzuki Y,Saitoh S,Kobayashi M,Kobayashi M,Suzuki F,Akuta N,Someya T,Kumada H

    更新日期:2003-01-01 00:00:00

  • Nitric oxide regulates polarity of guinea pig distal colon pellet propagation and circular muscle motor response.

    abstract:BACKGROUND:Peristaltic reflex does not fully explain the polarity of peristalsis. In the distal colon, we propose that the balance of circular muscle contraction proximal and distal to the pellet is a local reflex that predicts polarity of peristalsis. METHODS:Guinea pig distal colon segments were harvested, and fecal...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0842-x

    authors: Gribovskaja-Rupp I,Kwak JM,Takahashi T,Ludwig K

    更新日期:2014-05-01 00:00:00

  • Combination of sorafenib and angiotensin-II receptor blocker attenuates preneoplastic lesion development in a non-diabetic rat model of steatohepatitis.

    abstract:BACKGROUND:Given the well-documented adverse side effects of sorafenib, many sorafenib-treated patients may need the reduced initial dose of the compound, and an alternative sorafenib-based therapy, which exerts similar clinical benefit, is anticipated. An angiostatic therapy with sorafenib is considered one of the pro...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0906-y

    authors: Yoshiji H,Noguchi R,Namisaki T,Moriya K,Kitade M,Aihara Y,Douhara A,Kawaratani H,Nishimura N,Fukui H

    更新日期:2014-10-01 00:00:00

  • Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling.

    abstract:BACKGROUND:Gastric cancer stem cells (CSCs), which require activation of Wnt signaling to maintain their self-renewal and tumorigenicity, are proposed to be critical targets for effective therapy of gastric carcinomas. Gene therapies that are delivered by adenovirus of serotype 5 (Ad5) or chimeric 5/35(Ad5/35) adenovir...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0711-z

    authors: Wang B,Liu J,Ma LN,Xiao HL,Wang YZ,Li Y,Wang Z,Fan L,Lan C,Yang M,Hu L,Wei Y,Bian XW,Chen D,Wang J

    更新日期:2013-07-01 00:00:00

  • Effect of age and correlation between esophageal visceral chemosensitivity and mechanosensitivity in healthy Japanese subjects.

    abstract:BACKGROUND:The aim of this study was to examine the impact of age on esophageal sensation, and to determine whether esophageal mechanosensitivity and chemosensitivity are correlated in healthy Japanese subjects. METHODS:To evaluate chemosensitivity, a catheter was inserted and placed 10 cm above the upper border of th...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0665-1

    authors: Yamasaki T,Oshima T,Tomita T,Kondo T,Toyoshima F,Sakurai J,Fukui H,Matsumoto T,Watari J,Miwa H

    更新日期:2013-03-01 00:00:00

  • Role of endogenous substance P in ethanol-induced mucosal damage in the rat stomach.

    abstract::To determine the role of endogenous substance P in ethanol-induced mucosal damage, two experiments were performed. In the first experiment, the stomachs of anesthetized rats were doubly cannulated and gastric damage was induced with 5ml of 30% ethanol in the gastric lumen. The damage was ameliorated by pretreatment wi...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF02355018

    authors: Hayashi H,Nishiyama K,Majima M,Katori M,Saigenji K

    更新日期:1996-06-01 00:00:00

  • Portal venous blood flow while breath-holding after inspiration or expiration and during normal respiration in controls and cirrhotics.

    abstract::In this study, we used magnetic resonance (MR) imaging to measure portal blood flow in 12 healthy controls and 17 cirrhotics while they were breath-holding after inspiration and after expiration. We then compared the results with measurements made during normal respiration in the healthy controls and cirrhotics. Blood...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050381

    authors: Sugano S,Yamamoto K,Sasao K,Watanabe M

    更新日期:1999-10-01 00:00:00

  • Impairment of chemical clearance and mucosal integrity distinguishes hypersensitive esophagus from functional heartburn.

    abstract:BACKGROUND:Hypersensitive esophagus (HE) is defined by endoscopy-negative heartburn with a normal acid exposure time but positive symptom association probability (SAP) and/or symptom index (SI) on impedance-pH monitoring, and proton pump inhibitor (PPI) responsiveness. Functional heartburn (FH) is distinguished by nega...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00535-016-1226-9

    authors: Frazzoni M,de Bortoli N,Frazzoni L,Furnari M,Martinucci I,Tolone S,Farioli A,Marchi S,Fuccio L,Savarino V,Savarino E

    更新日期:2017-04-01 00:00:00

  • Which patients respond best to hepatitis B vaccination after a hepatitis B virus-related liver transplantation?

    abstract:BACKGROUND:A combination of hepatitis B immunoglobulin and nucleos(t)ide analogues is the current standard of care for controlling hepatitis B recurrence after orthotopic liver transplantation (OLT). However, frequent immunoglobulin treatment is expensive and inconvenient. This study investigated the efficacy of hepati...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-013-0763-8

    authors: Takaki A,Yagi T,Yasunaka T,Sadamori H,Shinoura S,Umeda Y,Yoshida R,Sato D,Nobuoka D,Utsumi M,Yasuda Y,Nakayama E,Miyake Y,Ikeda F,Shiraha H,Nouso K,Fujiwara T,Yamamoto K

    更新日期:2013-12-01 00:00:00

  • Epidemiological study of ulcerative colitis in Japan: incidence and familial occurrence. The Epidemiology Group of the Research Committee of Inflammatory Bowel Disease in Japan.

    abstract::Epidemiological studies of ulcerative colitis (UC) have been conducted once every year since 1973 in Japan. The number of participating hospitals in 1429 and they are distributed throughout Japan. A total number of 10819 patients diagnosed with UC have been registered, including 197 patients with a positive family his...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Kitahora T,Utsunomiya T,Yokota A

    更新日期:1995-11-01 00:00:00