Abstract:
BACKGROUND:Wide pulse pressure is a potent risk factor for atherosclerotic disease, and hypertension is induced by habitual alcohol drinking. This concise study investigated whether age affects the relationship between alcohol drinking and pulse pressure. METHODS:The participants were 99 661 male workers (20-69 years old) who had received periodic health check-ups. The mean levels of pulse pressure and blood pressure were compared among three different groups divided by the average amount of daily alcohol intake (nondrinkers; light drinkers, < 30 g ethanol/day; heavy drinkers, >or= 30 g ethanol/day) in each age group. RESULTS:The mean pulse pressure was decreased in the thirties and forties age groups compared with that in the twenties age group, and then was increased with advance of age in the fifties and sixties age groups. Pulse pressure was significantly wider in heavy drinkers than in nondrinkers and light drinkers in all age groups, and the difference between pulse pressure of nondrinkers and that of heavy drinkers was greater in the fifties and sixties age groups than in the younger groups. Pulse pressure in light drinkers was significantly wider than that in nondrinkers in the fifties and sixties age groups but was not different from that in nondrinkers in the twenties to forties age groups. CONCLUSIONS:Association of alcohol intake with pulse pressure is dependent on the amount of alcohol and is stronger in the elderly. Age as well as amount of alcohol intake should therefore be taken into account when the influence of alcohol drinking on pulse pressure is considered.
journal_name
J Hypertensjournal_title
Journal of hypertensionauthors
Wakabayashi Idoi
10.1097/HJH.0b013e3280895b69subject
Has Abstractpub_date
2007-05-01 00:00:00pages
971-5issue
5eissn
0263-6352issn
1473-5598pii
00004872-200705000-00013journal_volume
25pub_type
杂志文章abstract:OBJECTIVE:To characterize an ATP-sensitive K+ channel at the single-channel and tissue level in the vascular smooth muscle of normotensive and genetically hypertensive rats. METHODS:Age- and sex-matched Wistar-Kyoto (WKY) rats and stroke-prone spontaneously hypertensive rats (SHRSP) were used. Patch-clamp single-chann...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199310000-00010
更新日期:1993-10-01 00:00:00
abstract:OBJECTIVE:Hypertensive nephropathy is one of the major causes of chronic kidney disease (CKD). Bisphenol A (BPA) is associated with elevated blood pressure and urinary albuminuria. The aim of this study is to evaluate the association between serum BPA with the progression of CKD in patients with primary hypertension. ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000000780
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Recent cross-sectional studies have suggested that higher serum sodium levels may be a marker of elevated blood pressure. It is unclear whether serum sodium levels are related to the risk of developing hypertension in the community. METHODS:We investigated the association of serum sodium with longitudinal b...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32830fe4a5
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:The objective of this study was to estimate the prevalence and distribution of hypertension and to determine the status of hypertension awareness, treatment and control in the Portuguese adult population. METHODS:This study was conducted in 2003, and a multistage cluster sampling method was used to select a...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/01.hjh.0000179908.51187.de
更新日期:2005-09-01 00:00:00
abstract:OBJECTIVES:Studies regarding the effects of parity on blood pressure in later life produced conflicting results. The aim of our study is to analyse whether parity influences the prevalence of hypertension in perimenopausal and postmenopausal women. METHODS:One thousand perimenopausal and postmenopausal women (mean age...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e32835c1742
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to examine the associations of birth outcomes and longitudinally measured fetal and infant growth patterns with retinal vessel calibers in childhood. METHODS:In a population-based prospective cohort study among 4122 children, we measured growth characteristics in second and third tri...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000000561
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the incidence of hypertension and the rate of decline in renal function in a sample of 47 Olivetti Heart Study (OHS) participants whose blood pressure (BP) salt-sensitivity and renal tubular sodium handling had been assessed in 1987-88. METHODS:During the 2002-04 OHS follow-up examination, medica...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3281139ebd
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Peroxisome proliferator-activated receptor (PPAR)-alpha has been implicated in the regulation of normal and pathological cellular functions, but the effect of specific gene silencing on PPARalpha-mediated function is not fully defined. AIM:This study evaluated the role of PPARalpha in hypertensive renal inj...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328330b6d9
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:Circulating biomarkers of endothelial dysfunction and inflammation are elevated in late pregnancy in women with preeclampsia. We examined plasma levels of inflammatory cytokines and adhesion molecules in early pregnancy, to assess their ability to predict preeclampsia. METHODS:In a prospective longitudinal s...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328352573b
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVES:To test whether the Glu298Asp polymorphism of the endothelial nitric oxide synthase (eNOS) gene is of functional relevance in humans by altering endothelium-dependent vasodilation. BACKGROUND:The Asp298 variant of the eNOS gene product has been associated with arterial hypertension, coronary artery disease ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200018120-00010
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVES:We hypothesized that the aldosterone: renin ratio (ARR) predicts the antihypertensive response to mineralocorticoid receptor antagonist, spironolactone (SPIRO), when compared with bendroflumethiazide (BFZ). METHODS:We conducted a randomized, crossover, trial on hypertensive patients with either high ARR (HA...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/HJH.0b013e328332b79b
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVES:Unlike the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guideline, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline has recommended a shift in hypertension definition from blood pressure (BP) 140/90-130/80 mmHg. Further, they proposed so...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002065
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To measure blood pressure accurately, by developing a new algorithm and an indirect method employing a non-elastic cuff with a photosensor. DESIGN AND METHODS:A non-elastic cuff was wrapped around the brachium. A reflecting plate (10 mm x 40 mm) was sited on the inner central part of the cuff on the arterial...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199715020-00005
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To evaluate whether efficacious counseling methods on sodium restriction can be successfully incorporated into primary care models for the management of hypertension. METHODS:We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects and Health Te...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/HJH.0000000000000182
更新日期:2014-07-01 00:00:00
abstract::This study determined the influence of baroreflex sensitivity (BRS) on the rate of urinary sodium excretion and plasma renin activity (PRA) in response to a saline infusion in conscious male rabbits specifically bred for high (Group I; n = 7) and low (Group II; n = 10) BRS and in seven control animals. Only Group II s...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-199109000-00005
更新日期:1991-09-01 00:00:00
abstract:PURPOSE:To study the feasibility of vascular mechanics at the aortic arch with two-dimensional speckle tracking echocardiography, as well as to define normal values and to compare results between hypertensive patients and healthy patients. METHODS:We included 107 patients (61 healthy patients and 46 hypertensive patie...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000001336
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:High blood pressure is common in acute stroke and is associated independently with poor outcome. Lowering blood pressure might improve outcome, provided it does not reduce cerebral blood flow in the presence of dysfunctional cerebral autoregulation. METHODS:We performed a systematic review of clinical contro...
journal_title:Journal of hypertension
pub_type: 杂志文章,meta分析
doi:10.1097/HJH.0b013e3282fbd240
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Arterial stiffness is an independent predictor of cardiovascular events and mortality in hypertensive patients. The influence of different antihypertensive drug classes on improving arterial stiffness beyond blood pressure reduction is not widely available. We aimed to determine whether the artery stiffness ...
journal_title:Journal of hypertension
pub_type: 杂志文章,meta分析
doi:10.1097/HJH.0b013e328346a583
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVE:Studies were undertaken to clarify the pathophysiologic significance of endogenous endothelin in the control of blood pressure and renal hemodynamics in spontaneously hypertensive rats (SHR). DESIGN:The technique of passive immunization was used to neutralize endogenous endothelin in order to estimate the co...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVES:We recently demonstrated that glucocorticoid increases the number of angiotensin II type 1 (AT1) receptors and their gene expression in cultured vascular smooth muscle cells. To clarify whether this mechanism participates in glucocorticoid-induced hypertension, we investigated the effect of dexamethasone on ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract:OBJECTIVE:To validate a computer-based method for measuring the calibre of retinal blood vessels, and use it to determine the effects of ageing and arterial hypertension on the calibres of these vessels and on their ratio. METHODS:Digital eye fundus images covering a 50 degrees field and centred on the optic disc were...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章
doi:10.1097/01.hjh.0000163154.35577.8e
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:The apolipoprotein epsilon 4 allele (APOE/epsilon 4) increases plasma cholesterol level and the risk for the late onset type of Alzheimer's disease. However, the correlation between hypertension and APOE/epsilon 4 has not yet been clarified. To examine the APOE/epsilon 4 effect in the general population of J...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/00004872-200210000-00021
更新日期:2002-10-01 00:00:00
abstract::Hypertension is a leading risk factor for mortality. Detecting, treating and monitoring hypertensive patients require accurate blood pressure measurements. Protocols for validation of automatic sphygmomanometers exist, but quality control of validations is limited to peer review of published reports, which has severe ...
journal_title:Journal of hypertension
pub_type: 杂志文章,评审
doi:10.1097/HJH.0b013e32833e1011
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Postmenopausal estrogen replacement, with or without progestins, has been related to lower cardiovascular risks. OBJECTIVE:We investigated whether the actions of estrogen on vascular resistance contribute to this cardioprotective effect. DESIGN AND METHODS:In a 6-month double-blind study, pre- and post-tre...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00004872-200102000-00014
更新日期:2001-02-01 00:00:00
abstract::The European Society of Hypertension and the European Society of Cardiology have started the preparation of the third edition of their joint guidelines on the management of arterial hypertension. The authors have focused on the new edition of the UK NICE guidelines to learn about the difficulties of disentangling evid...
journal_title:Journal of hypertension
pub_type: 社论
doi:10.1097/HJH.0b013e328351b4e4
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Recent studies indicated that central SBP could be estimated by radial late-SBP (rSBP2) with a small disparity. However, most of these studies were conducted by SphygmoCor with a transfer function. The agreement between rSBP2 and central SBP was also tested in several invasive studies, but with inconsistent ...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e328342f05f
更新日期:2011-04-01 00:00:00
abstract::: Phaeochromocytoma and paraganglioma (PPGL) are chromaffin cell tumours that require timely diagnosis because of their potentially serious cardiovascular and sometimes life- threatening sequelae. Tremendous progress in biochemical testing, imaging, genetics and pathophysiological understanding of the tumours has far-...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0000000000002438
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVES:Recent epidemiological studies have reported inverse associations between vitamin D status and blood pressure. The study aim is to determine if exposure to ultraviolet B radiation, which synthesizes vitamin D, lowers blood pressure, compared with ultraviolet A radiation. METHODS:Men and women (n = 119) with...
journal_title:Journal of hypertension
pub_type: 杂志文章,随机对照试验
doi:10.1097/HJH.0b013e328349666d
更新日期:2011-09-01 00:00:00
abstract::The fall in blood pressure that is commonly observed when groups of hypertensive individuals are followed without treatment is usually ascribed to two sources: regression towards the mean and increasing familiarity of the subject with the assessment process. Any effect of the latter process could bias the results of c...
journal_title:Journal of hypertension
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-06-01 00:00:00
abstract:BACKGROUND:Ambulatory blood pressure (BP) monitoring (ABPM) detects subjects with normal clinic but high ambulatory 24-h BP, that is, masked hypertension. METHODS:One hundred and thirty newly diagnosed obstructive sleep apnea syndrome (OSAS) patients, free of recognized cardiovascular disease were included (111 men, a...
journal_title:Journal of hypertension
pub_type: 杂志文章
doi:10.1097/HJH.0b013e3282f55049
更新日期:2008-05-01 00:00:00