Longing for clinical excellence: a critical outlook into the NICE recommendations on hypertension management--is nice always good?

abstract：OBJECTIVE:To determine whether the decision to treat uncomplicated mild hypertension with drugs, in accordance with the World Health Organization - International Society of Hypertension (WHO/ISH) guidelines based on a series of blood pressure (BP) measurements over 6 months, resulted in the treatment of patients at hig...

journal_title：Journal of hypertension

authors： Abergel E,Chatellier G,Battaglia C,Menard J

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:Despite the widespread use of multivitamin supplements, little is known regarding their effects on blood pressure (BP) and the development of hypertension. We, therefore, sought to prospectively investigate how multivitamin use was associated with incident hypertension among middle-aged and older women. METH...

journal_title：Journal of hypertension

authors： Rautiainen S,Wang L,Lee IM,Manson JE,Gaziano JM,Buring JE,Sesso HD

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:Many different stress echocardiographic and radionuclide perfusion imaging tests have been proposed for detecting epicardial coronary artery disease (CAD) in hypertensive patients. Their relative diagnostic and prognostic value has not been exactly established. BACKGROUND:A positive exercise electrocardiogr...

journal_title：Journal of hypertension

authors： Astarita C,Pálinkás A,Nicolai E,Maresca FS,Varga A,Picano E

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:Urotensin II is the most potent vasoconstrictor known. Its role in hypertension has not been investigated. Here, we studied the plasma levels in hypertensive and normotensive human subjects. DESIGN:A cross-sectional case-control study. SETTING:Hypertension clinic and research clinic of a university teachin...

journal_title：Journal of hypertension

authors： Cheung BM,Leung R,Man YB,Wong LY

更新日期：2004-07-01 00:00:00

abstract：:The effect of xipamide on the intracellular concentration and transmembrane fluxes of Na+ and K+ was studied in 12 normal male subjects, using a double-blind cross-over design. After a run-in period on placebo for 1 week, the subjects were treated with either placebo (n = 6) or xipamide 20 mg once a day (n = 6) for 16...

journal_title：Journal of hypertension

authors： Lijnen P,Hespel P,Fagard R,Staessen J,Goossens W,Lissens W,Amery A

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:Angiotensin (Ang) II increases reactive oxygen species (ROS), decreases nitric oxide (NO) bioavailability and promotes cardiovascular remodeling. ROS have been identified as critical second messengers of the trophic responses by Ang II. In rats with Ang II-induced hypertension, we investigated the role of ROS...

journal_title：Journal of hypertension

authors： Zhou MS,Jaimes EA,Raij L

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVE:To compare the elastic properties of the ascending aorta and ventricular-arterial coupling (VAC) in women with a previous pregnancy complicated by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome, women who experienced preeclampsia, and healthy controls. METHODS:Women with a history of p...

journal_title：Journal of hypertension

authors： Sciatti E,Orabona R,Prefumo F,Vizzardi E,Bonadei I,Valcamonico A,Metra M,Frusca T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of the haem oxygenase-carbon monoxide (CO) system to renal vascular tone in normotensive Wistar rats and in the stroke-prone spontaneously hypertensive rats (SHR-SPs). METHODS:An isolated perfused rat kidney preparation was used in which perfusion pressure/phenylephrine dose-vaso...

journal_title：Journal of hypertension

authors： Mustafa MR,Johns EJ

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To conduct a longitudinal evaluation of the central haemodynamic adaptations of normal pregnancy. METHODS:This was a prospective longitudinal study involving healthy, normotensive women who were having an uncomplicated, singleton pregnancy. Brachial and central SBP, DBP, mean arterial pressure (MAP), brachia...

journal_title：Journal of hypertension

authors： O' Callaghan KM,Hennessy Á,Malvisi L,Kiely M

更新日期：2018-10-01 00:00:00

abstract：INTRODUCTION:Several renal denervation (RDN) systems are currently under investigation for treatment of hypertension by ablation of renal sympathetic nerves. The procedural efficacy of devices, however, is variable and incompletely understood. This study aimed at investigating procedural and anatomical predictors of RD...

journal_title：Journal of hypertension

authors： Wolf M,Hubbard B,Sakaoka A,Rousselle S,Tellez A,Jiang X,Kario K,Hohl M,Böhm M,Mahfoud F

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:We tested the hypothesis that qualitative microalbuminuria (MAU) screening in a practice setting would identify non-diabetic hypertensive patients at high risk of developing cardiovascular disease. DESIGN:We enrolled general practitioners throughout Germany, who obtained histories, physical examinations, and...

journal_title：Journal of hypertension

authors： Agrawal B,Berger A,Wolf K,Luft FC

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:This study presents a reliable index inspired by the total variability concept of real analysis in mathematics, called average real variability (ARV), for the prognostic significance of blood pressure variability (BPV) overcoming the pitfalls of the commonly used standard deviation (SD). BACKGROUND:Recent s...

journal_title：Journal of hypertension

authors： Mena L,Pintos S,Queipo NV,Aizpúrua JA,Maestre G,Sulbarán T

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:This study evaluated the impact of prolonged circulatory unloading and subsequent left ventricular (LV) mass decrease on LV myocardial performance. Five-week head-down tilt (-6°) bed rest (HDTBR) was used as a model of prolonged circulatory unloading. METHODS:Ten young healthy male volunteers (age 23 ± 2 yea...

journal_title：Journal of hypertension

authors： Kozàkovà M,Malshi E,Morizzo C,Pedri S,Santini F,Biolo G,Pagani M,Palombo C

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Familial hyperkalaemic hypertension (FHH) is a Mendelian form of low-renin hypertension characterized by hyperkalaemia and hyperchloraemic acidosis despite a normal glomerular filtration rate. To date, three different loci have been identified, on chromosomes 1, 17 and 12. OBJECTIVE:To test for genetic link...

journal_title：Journal of hypertension

authors： Disse-Nicodeme S,Desitter I,Fiquet-Kempf B,Houot AM,Stern N,Delahousse M,Potier J,Ader JL,Jeunemaitre X

更新日期：2001-11-01 00:00:00

abstract：:Nitric oxide formed by neuronal nitric oxide synthase (nNOS) in the brain, autonomic inhibitory (nitrergic) nerves, and heart plays important roles in the control of blood pressure. Activation of nitrergic nerves innervating the systemic vasculature elicits vasodilatation, decreases peripheral resistance, and lowers b...

journal_title：Journal of hypertension

authors： Toda N,Ayajiki K,Okamura T

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Few studies have directly compared the effects of different angiotensin receptor blockers (ARBs) on mechanisms involved in the pathogenesis of cardiovascular disease. METHODS:We studied the ability of different ARBs to inhibit the proliferation of vascular smooth muscle cells (VSMCs) and cardiac fibroblasts...

journal_title：Journal of hypertension

authors： Benson SC,Iguchi R,Ho CI,Yamamoto K,Kurtz TW

更新日期：2008-05-01 00:00:00

abstract：OBJECTIVE:We have previously reported that hearts from N-[omega]-nitro-L-arginine methyl ester (L-NAME)-induced hypertensive rats exhibited an enhanced expression of Gi proteins. Since, losartan, an AT1 receptor antagonist, has been shown to attenuate the L-NAME-induced increase in blood pressure, we undertook the pres...

journal_title：Journal of hypertension

authors： Hashim S,Anand-Srivastava MB

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:Unlike the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guideline, the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline has recommended a shift in hypertension definition from blood pressure (BP) 140/90-130/80 mmHg. Further, they proposed so...

journal_title：Journal of hypertension

authors： Gijón-Conde T,Sánchez-Martínez M,Graciani A,Cruz JJ,López-García E,Ortolá R,Rodríguez-Artalejo F,Banegas JR

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVE:Anemia is common in patients with heart failure and several factors have been thought to cause anemia in heart failure. Despite vigorous studies, the mechanism underlying the pathophysiology of anemia in heart failure is unknown. We investigated the iron regulating system in Dahl salt-sensitive heart failure ...

journal_title：Journal of hypertension

authors： Naito Y,Tsujino T,Fujimori Y,Sawada H,Akahori H,Hirotani S,Ohyanagi M,Masuyama T

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:Adenosine dilates rabbit renal arteries by an endothelium-dependent, nitric oxide (NO)- and prostaglandin-independent mechanism. The aim was to identify the responsible P1-purinoceptor subtype and to investigate the involvement of K+-channels. METHODS:Rabbit renal arteries were perfused with medium containin...

journal_title：Journal of hypertension

authors： Rump LC,Jabbari-T J,von Kügelgen I,Oberhauser V

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:In the past, different methods have been used to measure the carotid-femoral distance for the assessment of pulse wave velocity (PWV). However, the latest consensus published advises to use 80% of the direct straight carotid-femoral distance (D(0.8)) using either a flexible tape or a sliding c...

journal_title：Journal of hypertension

authors： Levi-Marpillat N,Desamericq G,Akakpo S,Affes-Ayadi H,Tropeano AI,Millasseau S,Macquin-Mavier I

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Blood pressure (BP) increases both in winter and in the last trimester of pregnancy. Some interaction seems to exist between season and gestational age. The present study observed home BP values during pregnancy with adjustment for seasonal variation and gestational age. METHODS:We observed 10353 home BP mea...

journal_title：Journal of hypertension

authors： Metoki H,Ohkubo T,Watanabe Y,Nishimura M,Sato Y,Kawaguchi M,Hara A,Hirose T,Obara T,Asayama K,Kikuya M,Yagihashi K,Matsubara Y,Okamura K,Mori S,Suzuki M,Imai Y,BOSHI Study Group.

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Endothelin is thought to be related to cardiovascular disease. The purpose of this study was to determine whether endothelin levels could be reduced by a calcium antagonist and a 'natural factor'. DESIGN:Since calcium ionophores can induce endothelin-1 messenger RNA synthesis in cultured endothelial cells, t...

journal_title：Journal of hypertension

authors： Liu JJ,Casley D,Wojta J,Gallicchio M,Dauer R,Buxton BF,Johnston CI

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:The screening for primary aldosteronism is based on the aldosterone-renin ratio calculated with the plasma renin activity (PRA) value as denominator. A direct measurement of active renin (DRA) is being used as an alternative to PRA, but its diagnostic performance remains unclear. METHOD:We, therefore compar...

journal_title：Journal of hypertension

authors： Rossi GP,Barisa M,Belfiore A,Desideri G,Ferri C,Letizia C,Maccario M,Morganti A,Palumbo G,Patalano A,Roman E,Seccia TM,Pessina AC,Mantero F,PAPY study Investigators.

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Chronic diabetes is associated with alterations in autonomic modulation of the cardiovascular system. Although the rat has been used extensively in studies of experimental diabetes, there have been no reports on the changes in autonomic modulation of the cardiovascular function in chronic diabetic rats. OBJ...

journal_title：Journal of hypertension

authors： Fazan R Jr,Dias da Silva VJ,Ballejo G,Salgado HC

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Recent reports have demonstrated increased cardiac risk, and an association with essential hypertension in patients with panic disorder. The cause is not known, but possibly involves sympathetic nervous activation. In this study, we evaluated the arterial baroreflex control of vascular sympathetic nervous ou...

journal_title：Journal of hypertension

authors： Lambert EA,Thompson J,Schlaich M,Laude D,Elghozi JL,Esler MD,Lambert GW

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To investigate the rate of albumin excretion and the prevalence of albuminuria in hypertensive individuals relative to the normotensive population, and to clarify the quantitative importance of confounding variables. DESIGN AND METHODS:We examined the morning urines of all consecutive non-diabetic and diabet...

journal_title：Journal of hypertension

authors： Hörner D,Fliser D,Klimm HP,Ritz E

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Beta-blockers are not recommended as the initial therapy for hypertension. Reports on associations between use of beta-blockers and stroke severity are inconclusive. We assessed associations between prestroke use of beta-blockers and stroke severity, poststroke disability and death in a large group of hypert...

journal_title：Journal of hypertension

authors： Koton S,Tanne D,Grossman E

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Essential hypertension is characterized by an impairment of endothelium-dependent vasodilatation. OBJECTIVE:To test whether antihypertensive treatment with the angiotensin converting enzyme inhibitor lisinopril can improve vasodilatation in response to endothelium-dependent agonists in essential hypertensiv...

journal_title：Journal of hypertension

authors： Taddei S,Virdis A,Ghiadoni L,Mattei P,Salvetti A

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:To compare the metabolite profiles of venous effluent from both kidneys of individuals with unilateral atherosclerotic renal artery stenosis (ARAS) in order to directly examine how impaired renal blood flow impacts small-molecule handling in humans. METHODS:We applied liquid chromatography-mass spectrometry ...

journal_title：Journal of hypertension

authors： Rhee EP,Clish CB,Pierce KA,Saad A,Lerman LO,Textor SC

更新日期：2015-04-01 00:00:00