Baseline level of platelet-leukocyte aggregates, platelet CD63 expression, and soluble P-selectin concentration in patients with posttraumatic stress disorder: a pilot study.

Abstract:

:Platelets may have an important role in the development of cardiovascular disease (CVD) as a result of chronic stress. We conducted a pilot study to evaluate the effect of posttraumatic stress disorder (PTSD) on baseline platelet activation. Platelet-leukocyte aggregates (PLA) and CD63 expression were measured by flow cytometry, and soluble (s)P-selectin concentration was determined in sera of 20 Croatian male combat veterans with PTSD and 20 healthy civilians. Groups were matched in sex, age, body mass index (BMI) and traditional CVD risk factors. Our data showed no differences in measured parameters. Other platelet activation markers should be determined and a larger sample size used in future studies.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Vidović A,Vilibić M,Markotić A,Sabioncello A,Gotovac K,Folnegović-Smalc V,Dekaris D

doi

10.1016/j.psychres.2006.05.004

subject

Has Abstract

pub_date

2007-03-30 00:00:00

pages

211-6

issue

2

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(06)00118-1

journal_volume

150

pub_type

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