Skin autofluorescence as a noninvasive marker of vascular damage in patients with type 2 diabetes.

abstract：OBJECTIVE:To assess the dose-ranging efficacy and safety of LX4211, a dual inhibitor of sodium-glucose cotransporter (SGLT) 1 and SGLT2, in type 2 diabetes. RESEARCH DESIGN AND METHODS:Type 2 diabetic patients inadequately controlled on metformin were randomly assigned to 75 mg once daily, 200 mg once daily, 200 mg tw...

journal_title：Diabetes care

authors： Rosenstock J,Cefalu WT,Lapuerta P,Zambrowicz B,Ogbaa I,Banks P,Sands A

更新日期：2015-03-01 00:00:00

abstract：:The goal of this study was to evaluate a program of resistance weight training on cardiovascular risk factors, blood glucose management, and overall strength in diabetic subjects. A randomized crossover design was performed on eight male type I (insulin-dependent) diabetic subjects (mean +/- SD age 31 +/- 3.5 yr, heig...

journal_title：Diabetes care

authors： Durak EP,Jovanovic-Peterson L,Peterson CM

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVE:To investigate the basis of central nervous system dysfunction in diabetes associated with the 3243 mitochondrial tRNA mutation, we studied neuroimaging findings in patients with this disease. RESEARCH DESIGN AND METHODS:We screened 205 diabetic patients. Those patients who had the 3243 mutation in leukocyte...

journal_title：Diabetes care

authors： Suzuki Y,Hata T,Miyaoka H,Atsumi Y,Kadowaki H,Taniyama M,Kadowaki T,Odawara M,Tanaka Y,Asahina T,Matsuoka K

更新日期：1996-07-01 00:00:00

abstract：:Significantly early-morning hyperglycemia was observed in insulin-dependent diabetic individuals who were otherwise well controlled while receiving a continuous subcutaneous insulin infusion (CSII) at standard doses. We measured the levels of the five key counterregulatory hormones (CRH) throughout the night for a tot...

journal_title：Diabetes care

authors： Geffner ME,Frank HJ,Kaplan SA,Lippe BM,Levin SR

更新日期：1983-03-01 00:00:00

abstract：OBJECTIVE:Numerous publications have already demonstrated that diabetes is a risk factor for the development of periodontal diseases and various inflammatory lesions in the oral mucosa. A possible correlation between diabetes and oral premalignancies and tumors was examined in this study, as no literature data are avai...

journal_title：Diabetes care

authors： Ujpál M,Matos O,Bíbok G,Somogyi A,Szabó G,Suba Z

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:The prevalence of systemic hypertension is increased in patients with diabetes. In this prospective, randomized, crossover clinical trial, we assessed antihypertensive effects of chronic intermittent intravenous insulin therapy (CIIIT) on insulin-dependent diabetes mellitus (IDDM) subjects with hypertension a...

journal_title：Diabetes care

authors： Aoki TT,Grecu EO,Prendergast JJ,Arcangeli MA,Meisenheimer R

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:To assess the impact of bariatric surgery (BS) on incident microvascular complications of diabetes-related foot disease (DFD), sight-threatening diabetic retinopathy (STDR), and chronic kidney disease (CKD) in patients with type 2 diabetes and obesity. RESEARCH DESIGN AND METHODS:A retrospective matched, con...

journal_title：Diabetes care

authors： Singh P,Adderley N,Subramanian A,Gokhale K,Singhal R,Toulis KA,Bellary S,Nirantharakumar K,Tahrani AA

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVE:Several meta-analyses of observational studies suggested that metformin use reduces cancer risk in type 2 diabetes. However, this result was not confirmed by the few available randomized controlled trials (RCTs), and many observational studies on metformin and cancer were potentially afflicted with time-relat...

journal_title：Diabetes care

authors： Kowall B,Rathmann W,Kostev K

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:To conduct a systematic review of cross-sectional and prospective human studies evaluating metabolite markers identified using high-throughput metabolomics techniques on prediabetes and type 2 diabetes. RESEARCH DESIGN AND METHODS:We searched MEDLINE and EMBASE databases through August 2015. We conducted a q...

journal_title：Diabetes care

authors： Guasch-Ferré M,Hruby A,Toledo E,Clish CB,Martínez-González MA,Salas-Salvadó J,Hu FB

更新日期：2016-05-01 00:00:00

abstract：:Nutrient intake plays a significant role in the health outcomes of all pregnant women. In a pregnancy complicated by gestational diabetes mellitus (GDM), excellent glucose control is as foundational as appropriate weight gain and adequate nutrient intake. The controversies in GDM management include the following: how ...

journal_title：Diabetes care

authors： Reader DM

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:Antioxidant trials have not demonstrated efficacy in slowing cardiovascular disease but could not rule out benefit for specific patient subgroups. Antioxidant therapy reduces LDL oxidizability in haptoglobin 1 allele homozygotes (Hp 1-1), but not in individuals with the haptoglobin 2 allele (Hp 2-1 or Hp 2-2)...

journal_title：Diabetes care

authors： Levy AP,Friedenberg P,Lotan R,Ouyang P,Tripputi M,Higginson L,Cobb FR,Tardif JC,Bittner V,Howard BV

更新日期：2004-04-01 00:00:00

abstract：:The prevalence of obesity among Hispanic American populations is generally greater than among white populations in the United States. Among Mexican Americans, the prevalence of obesity was higher than among either Cuban Americans or Puerto Ricans. It is well known that the prevalence of diabetes increases with increas...

journal_title：Diabetes care

authors： Nichaman MZ,Garcia G

更新日期：1991-07-01 00:00:00

abstract：OBJECTIVE:Pediatric type 2 diabetes prevalence is increasing, with β-cell dysfunction key in its pathogenesis. The RISE Pediatric Medication Study compared two approaches-glargine followed by metformin and metformin alone-in preserving or improving β-cell function in youth with impaired glucose tolerance (IGT) or recen...

journal_title：Diabetes care

authors： RISE Consortium.

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To examine the prevalence of cardiovascular disease in diabetic patients as a function of apolipoprotein (apo) E polymorphism. RESEARCH DESIGN AND METHODS:The apo E phenotypes and plasma lipid, lipoprotein, and apo levels were determined for 517 Italian diabetic patients. The prevalence of cardiovascular dis...

journal_title：Diabetes care

authors： Boemi M,Sirolla C,Amadio L,Fumelli P,Pometta D,James RW

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the effect of pharmacist care on cardiovascular disease (CVD) risk factors among outpatients with diabetes. RESEARCH DESIGN AND METHODS:MEDLINE, EMBASE, CINAHL, and the Cochrane Central Register of Controlled Trials were...

journal_title：Diabetes care

authors： Santschi V,Chiolero A,Paradis G,Colosimo AL,Burnand B

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To assess the additional effect of sudden visceral fat reduction by omentectomy on metabolic syndrome, acute-phase reactants, and inflammatory mediators in patients with grade III obesity (G-III O) undergoing laparoscopic Roux-en-Y gastric bypass (LRYGB). RESEARCH DESIGN AND METHODS:Twenty-two patients were ...

journal_title：Diabetes care

authors： Herrera MF,Pantoja JP,Velázquez-Fernández D,Cabiedes J,Aguilar-Salinas C,García-García E,Rivas A,Villeda C,Hernández-Ramírez DF,Dávila A,Zaraín A

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:To characterize immune checkpoint inhibitor-associated diabetes mellitus (ICI-DM) in a single-institution case series. RESEARCH DESIGN AND METHODS:Retrospective chart review of 18 patients with new-onset ICI-DM following anti-programmed cell death protein 1 (PD-1)/anti-programmed cell death protein ligand 1 ...

journal_title：Diabetes care

authors： Byun DJ,Braunstein R,Flynn J,Zheng J,Lefkowitz RA,Kanbour S,Girotra M

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To assess trends in rates of hospitalization for nontraumatic lower-extremity amputation (NLEA) in U.S. diabetic and nondiabetic populations and disparities in NLEA rates within the diabetic population. RESEARCH DESIGN AND METHODS:We calculated NLEA hospitalization rates, by diabetes status, among persons ag...

journal_title：Diabetes care

authors： Li Y,Burrows NR,Gregg EW,Albright A,Geiss LS

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Insulin and glucose levels in response to premeal insulin lispro or repaglinide were evaluated in adult patients with cystic fibrosis-related diabetes (CFRD) without fasting hyperglycemia. RESEARCH DESIGN AND METHODS:Seven patients with CFRD were fed 1,000-kcal liquid mixed meals. Three study conditions were...

journal_title：Diabetes care

authors： Moran A,Phillips J,Milla C

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:We assessed the association between early increases in albumin excretion and cardiovascular (CV) and renal markers in a large cohort of young people with type 1 diabetes. RESEARCH DESIGN AND METHODS:As part of preliminary screening for a multicenter, randomized controlled trial of statins/ACE inhibitors, we ...

journal_title：Diabetes care

authors： Marcovecchio ML,Woodside J,Jones T,Daneman D,Neil A,Prevost T,Dalton RN,Deanfield J,Dunger DB,AdDIT Investigators.

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of IDDM risk-associated HLA-DQ beta alleles in New Zealanders with IDDM and nondiabetic control subjects, and to examine these as susceptibility markers in relation to IDDM incidence. RESEARCH DESIGN AND METHODS:HLA-DQ beta typing was conducted in 55 juvenile-onset IDDM subjects di...

journal_title：Diabetes care

authors： Forbes LV,Brown LJ,Scott RS

更新日期：1993-08-01 00:00:00

abstract：:The prevalence of carotid artery occlusive disease (CAOD) in a population of adults with diabetes mellitus was determined, and factors associated with its presence were identified. By oculoplethysmography and phonoangiography, 20% of the population studied had detectable CAOD. Univariate analyses revealed that patient...

journal_title：Diabetes care

authors： Kuebler TW,Bendick PJ,Fineberg SE,Markand ON,Norton JA Jr,Vinicor FN,Clark CM Jr

更新日期：1983-05-01 00:00:00

abstract：:Intensive insulin therapy is best defined as a comprehensive system of diabetes management with the patient and management team as partners. The system is directed at improvement of glycemia and patient well-being. Glycemic targets should be individually defined. Frequent self-monitoring of blood glucose, probably at ...

journal_title：Diabetes care

authors： Hirsch IB,Farkas-Hirsch R,Skyler JS

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:Lifestyle interventions slow development of type 2 diabetes by half, but the impact of health payer reimbursement for delivery of intervention programs is not well known. We evaluated net commercial health payer expenditures when offering reimbursement for access to YMCA's Diabetes Prevention Program (YDPP) i...

journal_title：Diabetes care

authors： Ackermann RT,Kang R,Cooper AJ,Liss DT,Holmes AM,Moran M,Saha C

更新日期：2019-09-01 00:00:00

abstract：:We evaluated the epidemiology of diabetic ketoacidosis in the period 1960-1979. In Frederiksborg County, Denmark, the incidence of ketoacidosis at the county hospital increased from 60 per 100,000 in the period 1943-1963 to 120 per 100,000 in the period 1960-1979. In the investigation period we found an increasing inc...

journal_title：Diabetes care

authors： Ellemann K,Soerensen JN,Pedersen L,Edsberg B,Andersen OO

更新日期：1984-11-01 00:00:00

abstract：OBJECTIVE:To compare the glucose variability associated with insulin glargine and NPH/Lente insulin used as the basal insulin component of a multiple daily injection (MDI) regimen in pediatric patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Continuous glucose monitoring data were collected from a subset of ...

journal_title：Diabetes care

authors： White NH,Chase HP,Arslanian S,Tamborlane WV,4030 Study Group.

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:With increasing life expectancy in the U.S., it is important to know whether a longer life expectancy means a longer healthy life span or a prolonged period of later-life morbidity. This study examines changes in lifetime without diabetes, a leading cause of morbidity in later life. RESEARCH DESIGN AND METHO...

journal_title：Diabetes care

authors： Cunningham SA,Riosmena F,Wang J,Boyle JP,Rolka DB,Geiss LS

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:Dyslipidemia contributes to the progression of microvascular disease in diabetes. However, different lipid variables may be important at different stages of nephropathy. This study examines the pattern of dyslipidemia associated with the progression of nephropathy in patients with type 1 diabetes. RESEARCH D...

journal_title：Diabetes care

authors： Thomas MC,Rosengård-Bärlund M,Mills V,Rönnback M,Thomas S,Forsblom C,Cooper ME,Taskinen MR,Viberti G,Groop PH

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:This study tested the hypothesis that genetically raised hyperglycemia increases coronary artery disease (CAD) risk separately from the risk conferred by type 2 diabetes as a whole. RESEARCH DESIGN AND METHODS:We conducted a Mendelian randomization (MR) analysis using summary-level statistics from the larges...

journal_title：Diabetes care

authors： Merino J,Leong A,Posner DC,Porneala B,Masana L,Dupuis J,Florez JC

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The goal was to assess the 1-year efficacy and safety of the addition of pioglitazone or metformin to existing sulfonylurea (SU) therapy in patients with inadequately controlled type 2 diabetes. RESEARCH DESIGN AND METHODS:In this multicenter, double-blind study, patients were randomized to receive either pi...

journal_title：Diabetes care

authors： Hanefeld M,Brunetti P,Schernthaner GH,Matthews DR,Charbonnel BH,QUARTET Study Group.

更新日期：2004-01-01 00:00:00