Animal food intake and cooking methods in relation to endometrial cancer risk in Shanghai.

abstract：:Diagnosis of hereditary non-polyposis colorectal cancer (HNPCC) is currently based on phenotypical analysis of an expanded pedigree. Diagnostic guidelines ('Amsterdam criteria') proposed by the International Collaborative Group on HNPCC are often too stringent for use with small families. There is also the possibility...

journal_title：British journal of cancer

authors： Percesepe A,Anti M,Roncucci L,Armelao F,Marra G,Pahor M,Coco C,Gasbarrini G,Ponz de Leon M

更新日期：1995-11-01 00:00:00

abstract：:We screened 50 glioblastomas for P53 mutations. Five glioblastomas showed heterozygous mutations, while three were putatively heterozygous. Six of these eight glioblastomas showed elimination of wild-type P53 mRNA. These results strongly suggest that some sort of mechanism(s) favouring mutated over wild-type P53 mRNA ...

journal_title：British journal of cancer

authors： Szybka M,Zawlik I,Kulczycka D,Golanska E,Jesien E,Kupnicka D,Stawski R,Piaskowski S,Bieniek E,Zakrzewska M,Kordek R,Liberski PP,Rieske P

更新日期：2008-04-22 00:00:00

abstract：:We report the use of tumour antigen (TA-4) polyclonal antiserum to assess the level and pattern of TA-4 antigen expression in formalin-fixed paraffin-embedded tissue sections from 110 patients with a range of normal, dysplastic and malignant squamous epithelia from various sites in the upper aerodigestive tract. There...

journal_title：British journal of cancer

authors： Kearsley JH,Stenzel DJ,Sculley TB,Cooke RA

更新日期：1990-04-01 00:00:00

abstract：:The idea that chemotherapy can be used in combination with immunotherapy may seem somewhat counterproductive, as it can theoretically eliminate the immune cells needed for antitumour immunity. However, much preclinical work has now demonstrated that in addition to direct cytotoxic effects on cancer cells, a proportion...

journal_title：British journal of cancer

authors： Brown JS,Sundar R,Lopez J

更新日期：2018-02-06 00:00:00

abstract：:Epidermal growth factor receptor (EGFR) mutations are strong determinants of tumour response to EGFR tyrosine kinase inhibitors in non-small-cell lung cancer (NSCLC). Pleural effusion is a common complication of lung cancer. In this study, we assessed the feasibility of detection of EGFR mutations in samples of pleura...

journal_title：British journal of cancer

authors： Kimura H,Fujiwara Y,Sone T,Kunitoh H,Tamura T,Kasahara K,Nishio K

更新日期：2006-11-20 00:00:00

abstract：:The purpose of the study was to determine the response rates (RR) and duration to second- and third-line chemotherapy programmes in patients with anthracycline-resistant breast cancer, utilizing various definitions of anthracycline resistance. This was a retrospective analysis performed on 1335 patients with metastati...

journal_title：British journal of cancer

authors： Pivot X,Asmar L,Buzdar AU,Valero V,Hortobagyi G

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Aberrant choline metabolism has been proposed as a novel cancer hallmark. We recently showed that epithelial ovarian cancer (EOC) possesses an altered MRS-choline profile, characterised by increased phosphocholine (PCho) content to which mainly contribute over-expression and activation of choline kinase-alph...

journal_title：British journal of cancer

authors： Granata A,Nicoletti R,Tinaglia V,De Cecco L,Pisanu ME,Ricci A,Podo F,Canevari S,Iorio E,Bagnoli M,Mezzanzanica D

更新日期：2014-01-21 00:00:00

abstract：:Chemical structures of the sugar chains of various human alpha-fetoprotein (AFP) species with different affinity for Concanavalin A (Con A) and Lens culinaris agglutinin (LCA) were examined by pyridylamination of their oligosaccharides and stepwise exoglycosidase digestion. Using reversed-phase and size-fractionation ...

journal_title：British journal of cancer

authors： Aoyagi Y,Suzuki Y,Igarashi K,Saitoh A,Oguro M,Yokota T,Mori S,Suda T,Isemura M,Asakura H

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Topoisomerase I (Topo I) poisons (e.g., camptothecin (CPT)), used to treat cancer, cause DNA breaks that are most cytotoxic during S phase. PARP-1 promotes DNA repair and PARP inhibitors (PARPi) sensitise cells to Topo I poisons. We aimed to determine whether chemosensitisation is also S phase specific using...

journal_title：British journal of cancer

authors： Znojek P,Willmore E,Curtin NJ

更新日期：2014-09-23 00:00:00

abstract：:Circulating serum factors have been said to abrogate the effects of immune response in cancer, i.e. "blocking" and "antigenic inhibition". The aim of this investigation was to isolate such specific factors in a purified and native state. F(ab)2 fragments isolated from hypernephroma were insolubilized on the surfaces o...

journal_title：British journal of cancer

authors： Langvad E,Hydén H,Wolf H,Kroeigaard N

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Vismodegib has been used for the treatment of locally advanced basal cell carcinoma (laBCC) and metastatic BCC (mBCC) since 2011. Most efficacy and safety data are provided by clinical trials. This study evaluates the effectiveness of vismodegib for the treatment of laBCC, mBCC and basal cell nevus syndrome ...

journal_title：British journal of cancer

authors： Verkouteren BJA,Wakkee M,Reyners AKL,Nelemans P,Aarts MJB,Rácz E,Terra JB,Devriese LA,Alers RJ,Kapiteijn E,van Doorn R,Bekkenk MW,Reinders MGHC,Mosterd K

更新日期：2021-01-19 00:00:00

abstract：:Van Trommel et al have previously shown that serum human chorionic gonadotropin (hCG) cutoff levels can provide early prediction of resistance to first-line methotrexate (MTX) in patients with persistent trophoblastic disease (PTD). In this study, we validate this approach of prediction of resistance to single-agent c...

journal_title：British journal of cancer

authors： Kerkmeijer LG,Thomas CM,Harvey R,Sweep FC,Mitchell H,Massuger LF,Seckl MJ

更新日期：2009-03-24 00:00:00

abstract：:The identification of peptide vaccine candidates to date has been focused on human leukocyte antigen (HLA)-A2 and -A24 alleles. In this study, we attempted to identify cytotoxic T lymphocyte (CTL)-directed Lck-derived peptides applicable to HLA-A11(+), -A31(+), or -A33(+) cancer patients, because these HLA-A alleles s...

journal_title：British journal of cancer

authors： Naito M,Komohara Y,Ishihara Y,Noguchi M,Yamashita Y,Shirakusa T,Yamada A,Itoh K,Harada M

更新日期：2007-12-17 00:00:00

abstract：:Comparison of 9 and 35 GHz spectra, obtained from frozen and lyophilized tissues, with those from model systems containing ascorbic acid, confirm that the major component of the "lyophilization signal" of tissue is the ascorbyl radical, stabilized by adsorption on an inert matrix. The magnitude of the signal under ano...

journal_title：British journal of cancer

authors： Dodd NJ,Swartz HM

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Little is known about leukaemia risk following chronic radiation exposures at low dose rates. The Techa River Cohort of individuals residing in riverside villages between 1950 and 1961 when releases from the Mayak plutonium production complex contaminated the river allows quantification of leukaemia risks as...

journal_title：British journal of cancer

authors： Krestinina LY,Davis FG,Schonfeld S,Preston DL,Degteva M,Epifanova S,Akleyev AV

更新日期：2013-11-26 00:00:00

abstract：:Microsatellite instability is present in over 80% of the hereditary non-polyposis colorectal carcinoma and about 15-20% of the sporadic cancer. Microsatellite instability is caused by the inactivation of the mismatch repair genes, such as primarily hMLH1, hMSH2. To study the mechanisms of the inactivation of mismatch ...

journal_title：British journal of cancer

authors： Deng G,Peng E,Gum J,Terdiman J,Sleisenger M,Kim YS

更新日期：2002-02-12 00:00:00

abstract：BACKGROUND:Several microRNA (miRNA) molecules have emerged as important post-transcriptional regulators of tumour suppressor and oncogene expression. Ras association domain family member 1 (RASSF1) is a critical tumour suppressor that controls multiple aspects of cell proliferation such as cell cycle, cell division and...

journal_title：British journal of cancer

authors： Pruikkonen S,Kallio MJ

更新日期：2017-05-23 00:00:00

abstract：:Human primary thyroid follicular epithelial cells were transfected with a plasmid containing an origin-defective SV40 genome (SVori-) to produce several immortal cell lines. Two of the 10 cell lines analysed expressed specific features of thyroid epithelial function (iodide-trapping and thyroglobulin production). Thes...

journal_title：British journal of cancer

authors： Lemoine NR,Mayall ES,Jones T,Sheer D,McDermid S,Kendall-Taylor P,Wynford-Thomas D

更新日期：1989-12-01 00:00:00

abstract：:The expression of urokinase-type plasminogen activator (uPA) was investigated in squamous cell carcinoma of the human larynx. For this purpose, tissue extracts from 25 matched samples of normal mucosa and neoplastic larynx were compared for the levels of uPA activity as evaluated by a chromogenic PA assay and sodium d...

journal_title：British journal of cancer

authors： Parolini S,Flagiello D,Cinquetti A,Gozzi R,Cristini S,Cappiello J,Nicolai P,Rusnati M,Presta M,Tosatti MM

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Immune checkpoint blockade (ICB) therapy improved the prognosis of cancer patients, but general administration of ICBs occasionally induces side effects that include immune-related adverse events and tumour hyper-progression. Here, we established a protein-based system, by which endogenous expression of IC m...

journal_title：British journal of cancer

authors： Teratake Y,Takashina T,Iijima K,Sakuma T,Yamamoto T,Ishizaka Y

更新日期：2020-03-01 00:00:00

abstract：:The reaction patterns of eight antibodies directed against blood group substances A, B and H, respectively, against Lewis B antigen, difucosylated carbohydrate antigens (DFCA), gastrointestinal cancer antigen CA 19-9 (GICA), carcinoma-associated antigen CA-50 and CEA, were studied in 68 rectal carcinomas using the avi...

journal_title：British journal of cancer

authors： Enblad P,Glimelius B,Busch C,Pontén J,Påhlman L

更新日期：1987-05-01 00:00:00

abstract：:Detailed data were provided by the Oxford Survey of Childhood Cancer OSCC on deaths from childhood cancer in Britain after irradiation of the fetus during diagnostic radiology of the mother. In each age group at death, 0-5, 6-9 and 10-15 years, excess cancer deaths decreased suddenly for births in and after 1958. A ma...

journal_title：British journal of cancer

authors： Mole RH

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Cediranib is a highly potent inhibitor of vascular endothelial growth factor (VEGF) signalling with activity against all three VEGF receptors. Bevacizumab is an anti-VEGF-A monoclonal antibody with clinical benefit in previously treated metastatic colorectal cancer (mCRC). METHODS:Patients with mCRC who had...

journal_title：British journal of cancer

authors： Cunningham D,Wong RP,D'Haens G,Douillard JY,Robertson J,Stone AM,Van Cutsem E,HORIZON I study group.

更新日期：2013-02-19 00:00:00

abstract：:An attempt has been made to develop tritiated derivatives of Synkavit (menadiol sodium diphosphate, MNDP) of high specific activity as a radioactive drug.This paper summarizes the preliminary biological and physical studies, with emphasis on approximate radiation dosimetry and the necessary preliminary testing, and th...

journal_title：British journal of cancer

authors： Mitchell JS

更新日期：1974-05-01 00:00:00

abstract：:The 62 kDa protein product of the c-myc oncogene (p62 c-myc) is thought to be involved in the control of normal cellular proliferation and differentiation. We have measured oncoprotein levels using a flow cytometric assay in 141 operable breast cancers and have correlated levels with prognostic variables, patient surv...

journal_title：British journal of cancer

authors： Locker AP,Dowle CS,Ellis IO,Elston CW,Blamey RW,Sikora K,Evan G,Robins RA

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:Tumours are responsive to temozolomide (TMZ) if they are deficient in O(6)-methylguanine-DNA methyltransferase (MGMT), and mismatch repair (MMR) proficient. METHODS:The effect of TMZ on medulloblastoma (MB) cell killing was analysed with clonogenic survival assays. Expression of DNA repair genes and enzymes...

journal_title：British journal of cancer

authors： von Bueren AO,Bacolod MD,Hagel C,Heinimann K,Fedier A,Kordes U,Pietsch T,Koster J,Grotzer MA,Friedman HS,Marra G,Kool M,Rutkowski S

更新日期：2012-10-09 00:00:00

abstract：:We examined the associations of body mass index (BMI), waist circumference, a history of diabetes, and cigarette smoking with risk of pancreatic cancer among 37,147 women and 45,906 men followed up during 560,666 person-years in the Swedish Mammography Cohort and the Cohort of Swedish Men; 136 incident cases of pancre...

journal_title：British journal of cancer

authors： Larsson SC,Permert J,Håkansson N,Näslund I,Bergkvist L,Wolk A

更新日期：2005-11-28 00:00:00

abstract：:Insulin-like growth factors (IGFs) I and II are implicated in progression of various tumours including colorectal carcinomas. To interfere with the production of IGFs, we treated male nude mice bearing xenografts of HT-29 human colon cancer with various potent growth hormone-releasing hormone (GH-RH) antagonists. Twic...

journal_title：British journal of cancer

authors： Szepeshazi K,Schally AV,Groot K,Armatis P,Halmos G,Herbert F,Szende B,Varga JL,Zarandi M

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:WFDC1/Prostate stromal 20 (ps20) is a small secreted protein highly expressed within the prostate stroma. WFDC1/ps20 expression is frequently downregulated or lost in prostate cancer (PCa) and ps20 has demonstrated growth-suppressive functions in numerous tumour model systems, although the mechanisms of this...

journal_title：British journal of cancer

authors： Hickman OJ,Smith RA,Dasgupta P,Rao SN,Nayak S,Sreenivasan S,Vyakarnam A,Galustian C

更新日期：2016-05-24 00:00:00

abstract：BACKGROUND:Uterine serous papillary carcinoma (USPC) is a biologically aggressive variant of endometrial cancer. We investigated the expression of Serum Amyloid A (SAA) and evaluated its potential as a serum biomarker in USPC patients. METHODS:SAA gene and protein expression levels were evaluated in USPC and normal en...

journal_title：British journal of cancer

authors： Cocco E,Bellone S,El-Sahwi K,Cargnelutti M,Casagrande F,Buza N,Tavassoli FA,Siegel ER,Visintin I,Ratner E,Silasi DA,Azodi M,Schwartz PE,Rutherford TJ,Pecorelli S,Santin AD

更新日期：2009-07-21 00:00:00