Developmental and tissue-specific expression of rat T-kininogen.

abstract：:A monoclonal antibody (mAb) 25B1 directed against fetal bovine-serum acetylcholinesterase (FBS AChE) was used to examine the ability of the cholinergic enzyme to promote the assembly of amyloid-beta peptides (A beta) into Alzheimerś fibrils. This mAb binds to the peripheral anionic site of the enzyme and allostericall...

journal_title：Biochemical and biophysical research communications

authors： Reyes AE,Perez DR,Alvarez A,Garrido J,Gentry MK,Doctor BP,Inestrosa NC

更新日期：1997-03-27 00:00:00

abstract：:ShcA proteins mediate Erk1/Erk2 activation by integrins and epidermal growth factor (EGF), and are expressed as p46ShcA, p52ShcA, and p66ShcA. Although p52ShcA and p46ShcA mediate Erk1/Erk2 activation, p66ShcA antagonizes Erk activation. p66ShcA is spatially regulated during lung development, leading us to hypothesize...

journal_title：Biochemical and biophysical research communications

authors： Smith SM,Crowe DL,Lee MK

更新日期：2006-04-14 00:00:00

abstract：:Microfilaments play an important role in the formation of apoptotic bodies. This study examined expression patterns of beta-actin, a key component of microfilament, during apoptosis. The data suggest that continuous beta-actin expression is not required for formation of apoptotic bodies. beta-actin mRNA levels rapidly...

journal_title：Biochemical and biophysical research communications

authors： Naora H,Naora H

更新日期：1995-06-15 00:00:00

abstract：:Glucose tolerance factor partially purified from yeast extract powder stimulated [U-14C]-D-glucose uptake to a level 5.6 times greater than the basal level in the absence of insulin in isolated adipocytes prepared from rats fed with normal laboratory chow. The factor also stimulated 3-O-methylglucose transport 2.2-fol...

journal_title：Biochemical and biophysical research communications

authors： Tokuda M,Kashiwagi A,Wakamiya E,Oguni T,Mino M,Kagamiyama H

更新日期：1987-05-14 00:00:00

abstract：:Epidemiological and experimental data suggest a role for polyunsaturated fatty acids in the etiology of breast cancer. In this report we have studied arachidonic acid and linoleic acid metabolism in the human breast carcinoma cell line BT-20 which overexpresses both EGF receptor and the homologous erbB-2 oncogene prod...

journal_title：Biochemical and biophysical research communications

authors： Reddy N,Everhart A,Eling T,Glasgow W

更新日期：1997-02-03 00:00:00

abstract：:Expression of bone-associated proteins and osteoblastic transcription factor Runx2 in arterial cells has been implicated in the development of vascular calcification. However, the signaling upstream of the Runx2-mediated activation of osteoblastic program in vascular smooth muscle cells (VSMC) is poorly understood. We...

journal_title：Biochemical and biophysical research communications

authors： Nakahara T,Sato H,Shimizu T,Tanaka T,Matsui H,Kawai-Kowase K,Sato M,Iso T,Arai M,Kurabayashi M

更新日期：2010-04-02 00:00:00

abstract：:Our previous data from a human leukemic cell line made resistant to the nucleoside analog (NA) 9-β-D-arabinofuranosylguanine (AraG) revealed a massive upregulation of fetal hemoglobin (HbF) genes and the ABCB1 gene coding for the multidrug resistance P-glycoprotein (P-gp). The expression of these genes is regulated th...

journal_title：Biochemical and biophysical research communications

authors： Fyrberg A,Skoglund K,Wolk M,Lotfi K

更新日期：2012-10-26 00:00:00

abstract：:Platelet activating factor has been found to increase the intracellular level of free calcium (as monitored by the fluorescent calcium indicator quin-2) and to stimulate the turnover of the polyphosphoinositides in rabbit neutrophils. Calcium mobilization induced by platelet activating factor, in contrast to previous ...

journal_title：Biochemical and biophysical research communications

authors： Naccache PH,Molski MM,Volpi M,Becker EL,Sha'afi RI

更新日期：1985-07-31 00:00:00

abstract：:To clarify the presence of thromboxane A2 (TXA2) receptor in the colonic epithelium, we examined the effect of 9,11-epithio-11, 12-methano-thromboxane A2 (STA2), a stable analogue of TXA2, on intracellular free Ca2+ concentration ([Ca2+]i) of indo-1-loaded single cells in isolated rat colonic crypts by laser confocal ...

journal_title：Biochemical and biophysical research communications

authors： Ikari A,Sakai H,Sato T,Takeguchi N

更新日期：1999-05-19 00:00:00

abstract：:Bovine brain smg p25A, a guanine nucleotide-binding protein with a Mr of about 25,000, bound specifically GTP, guanosine 5'-(3-O-thio)triphosphate (GTP gamma S) and GDP. The initial velocities of the binding of GTP gamma S to GDP-bound smg p25A and the dissociation of GDP from this protein increased by decreasing Mg2+...

journal_title：Biochemical and biophysical research communications

authors： Shoji I,Kikuchi A,Kuroda S,Takai Y

更新日期：1989-07-14 00:00:00

abstract：:Herpes simplex virus-1 (HSV-1) glycoprotein E (gE) is a multifunctional protein capable of both binding the Fc portion of IgG and mediating cell-to-cell spread of HSV-1. Here we report that the domain on gE involved in IgG binding is distinct from the domain involved in mediating cell-to-cell spread. To do this we hav...

journal_title：Biochemical and biophysical research communications

authors： Weeks BS,Sundaresan P,Nagashunmugam T,Kang E,Friedman HM

更新日期：1997-06-09 00:00:00

abstract：:Metallothionein (MT) is believed to be a sensitive and effective "biomarker" for monitoring metal contamination in fish. Comparison of amino acid sequences between flounder MT and trout MT revealed that there is a conserved region at their N-terminals. Using oligonucleotides derived from this conserved region, reverse...

journal_title：Biochemical and biophysical research communications

authors： Chan KM

更新日期：1994-11-30 00:00:00

abstract：:The tumor suppressor p53, a 393-amino acid transcription factor with four domains, induces cell cycle arrest, senescence, and apoptosis in response to diverse stress. Tetramer formation is critical for the function of p53. The tetramerization domain permits the tetramerization of p53, where bundled four DNA-binding do...

journal_title：Biochemical and biophysical research communications

authors： Inobe T,Nozaki M,Nukina N

更新日期：2015-11-13 00:00:00

abstract：:The coffee-specific diterpenes cafestol and kahweol (C+K) have been identified as two important chemoprotective agents in coffee. In the present study, the potential preventive effects of C+K against the genotoxicity of B[a]P were investigated in rat primary hepatocytes and in human bronchial Beas-2B cells. Several in...

journal_title：Biochemical and biophysical research communications

authors： Cavin C,Bezencon C,Guignard G,Schilter B

更新日期：2003-06-27 00:00:00

abstract：:Stearoyl-CoA desaturase 1 (SCD1) deficiency partitions fatty acids away from lipid synthesis towards fatty acid oxidation in liver and skeletal muscle in part due to activation of AMP-activated protein kinase (AMPK) pathway. The mechanism of AMPK activation by SCD1 mutation is unknown, however since SCD1-/- animals ha...

journal_title：Biochemical and biophysical research communications

authors： Dobrzyn A,Dobrzyn P,Miyazaki M,Ntambi JM

更新日期：2005-07-08 00:00:00

abstract：:Using a human placenta cDNA library, we cloned a novel member belonging to the scavenger receptor family. Complementary DNA of this clone encodes a type II transmembranous glycoprotein containing a collagen-like domain, which are typical structural characteristics of scavenger receptor class A. This protein also conta...

journal_title：Biochemical and biophysical research communications

authors： Nakamura K,Funakoshi H,Miyamoto K,Tokunaga F,Nakamura T

更新日期：2001-02-02 00:00:00

abstract：:Dendritic cells (DCs) play an important role in vertebrate immunity, but little is known of the molecular events associated with their development from bone marrow (BM). This report describes induction of a signature protein marking BM commitment to DCs. Using a standard procedure, DCs were generated from BM by cultiv...

journal_title：Biochemical and biophysical research communications

authors： Al-Shaibi N,Ghosh SK

更新日期：2004-08-13 00:00:00

abstract：:NO production in platelets has been followed by electrochemical detection. It was undetectable in unstimulated platelets and in thrombin or ADP-stimulated platelets, but dose-dependently stimulated by collagen. A production of 5 10(-19) mol/platelet was reached with 9 micrograms collagen. In collagen-stimulated platel...

journal_title：Biochemical and biophysical research communications

authors： Lantoine F,Brunet A,Bedioui F,Devynck J,Devynck MA

更新日期：1995-10-24 00:00:00

abstract：:Near-full length complementary DNA (cDNA) clones encoding turkey growth hormone (GH) have been isolated from a pituitary library. The longer of the two turkey GH cDNA clones that were sequenced is 803 base pairs (bp) in length and contains 41 nucleotides of the 5'-untranslated region (UTR), an open reading frame of 64...

journal_title：Biochemical and biophysical research communications

authors： Foster DN,Kim SU,Enyeart JJ,Foster LK

更新日期：1990-12-31 00:00:00

abstract：:The nitric oxide synthases (NOS) are a class of enzymes responsible for the generation of NO via an oxygen and NADPH dependent oxidation of the amino acid arginine. These enzymes are ironheme proteins which contain FAD and FMN and, enigmatically, require tetrahydrobiopterin (BH4). NOS has recently been shown to be sub...

journal_title：Biochemical and biophysical research communications

authors： Hyun J,Komori Y,Chaudhuri G,Ignarro LJ,Fukuto JM

更新日期：1995-01-05 00:00:00

abstract：:Ku70 is a protein that finds itself at the heart of several important cellular processes. It is essential to the non-homologous end joining pathway as a part of the DNA-end binding complex, required for proper maintenance of telomeres and contributes to DNA damage recognition and regulation of apoptosis. Forces that r...

journal_title：Biochemical and biophysical research communications

authors： Yurchenko V,Xue Z,Gama V,Matsuyama S,Sadofsky MJ

更新日期：2008-02-01 00:00:00

abstract：:Glycosylation of endothelin (ET) receptors was found to occur in rat cerebellar and atrial membranes. Specifically, we investigated whether the ETA and ETB receptor subtypes differed in their sensitivity to deglycosylation treatment and whether the two affinity states (nanomolar and picomolar) observed in each recepto...

journal_title：Biochemical and biophysical research communications

authors： Shraga-Levine Z,Sokolovsky M

更新日期：1998-05-19 00:00:00

abstract：:ATP cassette binding protein 1 (ABCA1) controls the apolipoprotein-mediated cholesterol efflux pathway and determines plasma HDL levels. Although cAMP is known to promote ABCA1 expression and cholesterol efflux from cells, it has not been determined whether cyclic nucleotide phosphodiesterase (PDE) isoforms regulate t...

journal_title：Biochemical and biophysical research communications

authors： Lin G,Bornfeldt KE

更新日期：2002-01-18 00:00:00

abstract：:31P-NMR spectroscopy of rat liver perchloric acid extracts was utilized to assess the hepatic energy state in an experimental model of chronic dietary iron overload. Oral administration of iron for a period of 65 days that induces a steady ten-fold increase in hepatic iron concentration causes a significant decrease i...

journal_title：Biochemical and biophysical research communications

authors： Ceccarelli D,Predieri G,Muscatello U,Masini A

更新日期：1991-05-15 00:00:00

abstract：:The action of calpain (EC 3.4.22.17; Ca2+-dependent cysteine proteinase) on platelet factor XIII has been studied. Calpain I activated platelet factor XIII up to 76% of the maximum level observed with thrombin. Activation was accompanied by the limited proteolysis of the a subunit of platelet factor XIII to produce a ...

journal_title：Biochemical and biophysical research communications

authors： Ando Y,Imamura S,Yamagata Y,Kitahara A,Saji H,Murachi T,Kannagi R

更新日期：1987-04-14 00:00:00

abstract：:There is increasing evidence for the presence of cancer stem cells (CSCs) in malignant brain tumors, and these CSCs may play a pivotal role in tumor initiation, growth, and recurrence. Vascular endothelial growth factor (VEGF) promotes the proliferation of vascular endothelial cells (VECs) and the neurogenesis of neur...

journal_title：Biochemical and biophysical research communications

authors： Oka N,Soeda A,Inagaki A,Onodera M,Maruyama H,Hara A,Kunisada T,Mori H,Iwama T

更新日期：2007-08-31 00:00:00

abstract：:The (1)H NMR spectrum of the perchloric acid extract of carp seminal plasma was heavily congested. It is demonstrated that proton-detected C,H chemical shift correlation spectroscopy (HSQC, HSQC-TOCSY) allows an unequivocal identification of proline, glutamate, taurine, and methionine sulfoxide, although several key p...

journal_title：Biochemical and biophysical research communications

authors： Kalic M,Lauterwein J,Büsselmann G,Kamp G

更新日期：2000-03-05 00:00:00

abstract：:Induction of cyclin D1 expression is a critical feature of growth factor-induced cell proliferation in hepatocytes. To clarify the mechanisms regulating cyclin D1 gene expression, we isolated the rat cyclin D1 gene and analyzed the transcriptional regulatory elements in rat hepatoma cells and primary cultured rat hepa...

journal_title：Biochemical and biophysical research communications

authors： Moriuchi A,Ido A,Nagata Y,Nagata K,Uto H,Hasuike S,Hori T,Hirono S,Hayashi K,Tsubouchi H

更新日期：2003-01-10 00:00:00

abstract：:Monodisperse bovine prothrombin was prepared and its molecular states under several conditions examined. The protein showed no tendency to self-associate in the absence of calcium. Calcium (4 mM) caused small increases in the apparent molecular weight of the protein which may or may not represent protein dimerization ...

journal_title：Biochemical and biophysical research communications

authors： Silversmith RE,Wei GJ,Nelsestuen GL

更新日期：1983-02-28 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a cancer arising from the nasopharynx epithelium. Long non-coding RNAs (lnc RNA) play a critical role in various biological processes such as cell growth, embryonic development, and tumorigenesis. In the study, for the first time, we discovered that lnc RNA taurine upregulated gene 1 ...

journal_title：Biochemical and biophysical research communications

authors： Qian W,Ren Z,Lu X

更新日期：2019-01-29 00:00:00