Thrombin induces rapid PAR1-mediated non-classical FGF1 release.

abstract：:Small-angle X-ray scattering of one high molecular weight (HMW) subunit of wheat glutenin was measured at protein concentration ranges from 1.0 to 10.0 mg/ml. The radius of gyration of whole particles, RO, in aq. 50% (v/v) 1-propanol and 0.1M acetic acid was 16.6 +/- 0.1nm and 22.8nm, respectively, and the correspondi...

journal_title：Biochemical and biophysical research communications

authors： Matsushima N,Danno G,Sasaki N,Izumi Y

更新日期：1992-07-31 00:00:00

abstract：:We have cloned the 5' upstream -1034 to +88 fragment of the human inducible nitric oxide synthase (hiNOS) gene and demonstrate its competence to promote luciferase gene transcription in vascular-smooth-muscle (VSM) cells and macrophages. Sequential 5' end-deletions localized positive regulatory elements of hiNOS trans...

journal_title：Biochemical and biophysical research communications

authors： Kolyada AY,Savikovsky N,Madias NE

更新日期：1996-03-27 00:00:00

abstract：:It has been shown that anti-cancer drug induces secretion of serotonin (5-HT) from small intestine which activates serotonin type 3 (5-HT(3)) receptor to cause nausea and vomiting. In general, antagonist for 5-HT(3) receptor is used as anti-emetics during chemotherapy. However, we found that anti-cancer drug irinoteca...

journal_title：Biochemical and biophysical research communications

authors： Nakamura Y,Ishida Y,Yamada T,Shimada S

更新日期：2011-11-18 00:00:00

abstract：:The neuropeptide Y (NPY) system is known as one of the major neural signaling pathways. NPY, produced by peripheral tissues including osteoblasts, is known to bind to the Y1 receptor. Recently, osteoblast-specific Y1 receptor knockout mice were developed and were found to have a high bone mass phenotype, indicating a ...

journal_title：Biochemical and biophysical research communications

authors： Kurebayashi N,Sato M,Fujisawa T,Fukushima K,Tamura M

更新日期：2013-10-04 00:00:00

abstract：:Previous studies in our laboratory showed that ANP inhibits increases in endothelial monolayer permeability to macromolecules induced by thrombin. In this present study, we investigated the second messenger system involved in the influence of ANP on monolayer permeability. In bovine aortic endothelial cells (BAEC), AN...

journal_title：Biochemical and biophysical research communications

authors： Lofton CE,Newman WH,Currie MG

更新日期：1990-10-30 00:00:00

abstract：:We investigated the role of acyl-CoAs during induction and maintenance of long-term potentiation in rat brain hippocampus. Changes of acyl-CoA and free fatty acids (FFA) in hippocampus were measured during tetraethylammonium (TEA)-induced LTP. Results indicated that concentrations of acyl-CoAs and FFAs in slices were ...

journal_title：Biochemical and biophysical research communications

authors： Zhang Q,Yoshida S,Sakai K,Liu J,Fukunaga K

更新日期：2000-01-07 00:00:00

abstract：:Follicle-stimulating hormone (FSH) levels increase estrogen biosynthesis in obese menopausal women. Ovariectomized mice and 3T3-L1 cells were used to explore estrogen biosynthesis in the decline of ovarian function. After ovariectomy, lipid deposition, and FSH and estrogen levels changed, and feed intake increased sig...

journal_title：Biochemical and biophysical research communications

authors： Cui H,Zhao G,Wen J,Tong W

更新日期：2018-01-15 00:00:00

abstract：:To understand the molecular mechanisms involved in preleukemia, the suppression subtractive hybridization method was used in a murine radiation-induced thymic lymphoma model. Seventeen mRNAs overexpressed in preleukemic thymuses were identified: mouse laminin binding protein (p40/37LBP), E25 protein, Rattus norvegicus...

journal_title：Biochemical and biophysical research communications

authors： Verlaet M,Deregowski V,Denis G,Humblet C,Stalmans MT,Bours V,Castronovo V,Boniver J,Defresne MP

更新日期：2001-04-27 00:00:00

abstract：:Mycoplasma fermentans has been suspected as one of the causative pathogenic microorganisms of rheumatoid arthritis (RA) however, the pathogenic mechanism is still unclear. We, previously, reported that glycolipid-antigens (GGPL-I and III) are the major antigens of M. fermentans. Monoclonal antibody against the GGPL-II...

journal_title：Biochemical and biophysical research communications

authors： Kawahito Y,Ichinose S,Sano H,Tsubouchi Y,Kohno M,Yoshikawa T,Tokunaga D,Hojo T,Harasawa R,Nakano T,Matsuda K

更新日期：2008-05-02 00:00:00

abstract：:The human promyelocytic leukemia cell line, HL-60, stimulated with PMA, produced human HGF-like immunoreactivity (HL-60 HGF), which was detected with human HGF-specific ELISA. The purified HL-60 HGF was indistinguishable from human HGF in the plasma of patients with fulminant hepatic failure by studies of subunit cons...

journal_title：Biochemical and biophysical research communications

authors： Nishino T,Kaise N,Sindo Y,Nishino N,Nishida T,Yasuda S,Masui Y

更新日期：1991-11-27 00:00:00

abstract：:The cellular response to DNA damage induced by gamma-irradiation activates cell-cycle arrest to permit DNA repair and to prevent replication. Cyclin D1 is the key molecule for transition between the G1 and S phases of the cell-cycle, and amplification or overexpression of cyclin D1 plays pivotal roles in the developme...

journal_title：Biochemical and biophysical research communications

authors： Choo DW,Baek HJ,Motoyama N,Cho KH,Kim HS,Kim SS

更新日期：2009-01-23 00:00:00

abstract：:Changes in the intermediate filament composition of rat kidney proximal tubule cells in culture have been investigated. The data suggest that differentiated tubular epithelial cells do not express vimentin, but vimentin expression is induced when the cells begin to proliferate in culture. The cultured cells are positi...

journal_title：Biochemical and biophysical research communications

authors： Hatzinger PB,Chen Q,Dong LQ,Stevens JL

更新日期：1988-12-30 00:00:00

abstract：:Kaiso was previously described as a methylated DNA-binding protein and a transcription repressor interacting with the corepressor protein complex NCoR. In the current study, we show that generation-3 Kaiso knockout mice show a phenotype of splenomegaly and large diffused germinal centers (GC). In the spleens of Kaiso ...

journal_title：Biochemical and biophysical research communications

authors： Koh DI,Yoon JH,Kim MK,An H,Kim MY,Hur MW

更新日期：2013-12-13 00:00:00

abstract：:In order to characterize the direct involvement of cAMP in the change of osteoblast proliferation by parathyroid hormone (PTH), we employed the diastereoisomers of adenosine 3',5'-cyclic phosphorothioate, Sp-cAMPS and Rp-cAMPS, which have been recently shown to act directly as agonist and antagonist, respectively in t...

journal_title：Biochemical and biophysical research communications

authors： Kano J,Sugimoto T,Fukase M,Fujita T

更新日期：1991-05-31 00:00:00

abstract：:This investigation of Ca2+ requirements for the mitogenic activation of lymphocytes by periodic acid has shown that oxidation by periodate causes an immediate and transient increase of Ca2+ influx and efflux in oxidized cells. Oxidized lymphocytes maintained in the medium containing 0.2 mM Ca2+ failed to proliferate o...

journal_title：Biochemical and biophysical research communications

authors： Hornicek FJ,Malinin GI,Malinin TI

更新日期：1992-02-28 00:00:00

abstract：:GV1001, a synthetic peptide derived from human telomerase, has a range of diverse biological activities, including an antioxidant function. Here, we investigated the role of GV1001 in hepatitis C virus (HCV)-infected Huh7.5 (JFH-1) cells. We showed that GV1001 inhibited the production of ROS with decreased MAP kinase ...

journal_title：Biochemical and biophysical research communications

authors： Lee SA,Kim J,Sim J,Kim SG,Kook YH,Park CG,Kim HR,Kim BJ

更新日期：2016-02-26 00:00:00

abstract：:Using the garfish olfactory nerve, the time-courses of lateral expansion (swelling) and birefringence changes in nerve fibers have been examined at the site of application of electric current pulses. The effects of various chemical agents on these non-electrical signs of rapid structural changes in the nerve fibers ha...

journal_title：Biochemical and biophysical research communications

authors： Tasaki I,Byrne PM

更新日期：1992-10-30 00:00:00

abstract：:A 13 kb rat Cu/ZnSOD genomic clone has been purified from a rat liver genomic library and completely characterized by restriction mapping, detailed sequencing and Southern blot analysis. This gene spans approximately 6 kb and contains five exons and four introns. Comparison of rat, mouse, and human Cu/ZnSOD genes reve...

journal_title：Biochemical and biophysical research communications

authors： Hsu JL,Visner GA,Burr IA,Nick HS

更新日期：1992-07-31 00:00:00

abstract：:AtNPF7.3/AtNRT1.5, which is a nitrate transporter that drives root-to-shoot transport of NO3-, is also involved in modulating the response to K+ deprivation in Arabidopsis by affecting root development and K+ transport. However, whether NPF7.3/NRT1.5 functions in regulating plant responses to deficiencies of other nut...

journal_title：Biochemical and biophysical research communications

authors： Cui YN,Li XT,Yuan JZ,Wang FZ,Wang SM,Ma Q

更新日期：2019-01-01 00:00:00

abstract：:The responsiveness of the human mammary carcinoma cell line MCF-7 to estradiol and tamoxifen treatment has been studied in different culture conditions. Cells from exponentially growing cultures were compared with cells in their initial cycles after replating from confluent cultures ("confluent-log" cells). It has bee...

journal_title：Biochemical and biophysical research communications

authors： Jozan S,Faye JC,Tournier JF,Tauber JP,David JF,Bayard F

更新日期：1985-11-27 00:00:00

abstract：:Stromal cell-derived factor 1 (SDF-1) regulates neovascularization, which is coordinately controlled by endothelial cells (EC) and their surrounding cells, pericytes or smooth muscle cells. In the basal state, SDF-1 expression is much lower in EC than in their surrounding cells. In this study, we evaluated epigenetic ...

journal_title：Biochemical and biophysical research communications

authors： Seo J,Kim YO,Jo I

更新日期：2009-05-08 00:00:00

abstract：:A previous study showed that small G protein signaling modulator 3 (SGSM3) was highly correlated with Cx43 in heart functions and that high levels of SGSM3 may induce Cx43 turnover through lysosomal degradation in infarcted rat hearts. Here, we investigated the protective effects of kenpaullone on cardiomyocytes follo...

journal_title：Biochemical and biophysical research communications

authors： Joo HC,Choi JW,Moon H,Lee CY,Yoo KJ,Kim SW,Hwang KC

更新日期：2018-05-05 00:00:00

abstract：:We have studied the convergence of the biosynthetic lysosomal route marked by the newly synthesized lysosomal enzyme arylsulfatase A (ASA) with the endosomal/prelysosomal compartment in ASA overexpressing baby hamster kidney (BHK) cells. A monoclonal antibody against ASA conjugated to transferrin (Tf-alpha ASA) was us...

journal_title：Biochemical and biophysical research communications

authors： Diesner F,Sommerlade HJ,Braulke T

更新日期：1993-11-30 00:00:00

abstract：:Abnormal lipid metabolism may contribute to the pathogenesis of non-alcoholic steatohepatitis (NASH). The ATP-binding cassette transporter A1 (ABCA1) protein mediates the transport of cholesterol and phospholipids from cells to apolipoprotein A-I (apoA-I) to generate nascent HDL particles. Previous studies revealed th...

journal_title：Biochemical and biophysical research communications

authors： Liang H,Wang Y

更新日期：2018-04-06 00:00:00

abstract：:Drosophila Dicer-2 processes RNA substrates into short interfering RNAs (siRNAs). Loquacious-PD (Loqs-PD), a dsRNA-binding protein that associates with Dicer-2, is required for processing of a subset of RNA substrates including hairpin RNAs into siRNAs. Inorganic phosphate-a small molecule present in all cell types-in...

journal_title：Biochemical and biophysical research communications

authors： Fukunaga R

更新日期：2018-04-15 00:00:00

abstract：:Auxins regulate various aspects of plant growth and development. However, the mechanism by which these hormones elicit diverse physiological processes is not clear. We present evidence for the role of auxin in protein phosphorylation and the possible involvement of calmodulin in auxin-induced changes. In the presence ...

journal_title：Biochemical and biophysical research communications

authors： Reddy AS,Chengappa S,Poovaiah BW

更新日期：1987-04-29 00:00:00

abstract：:Ceramide acts as a second messenger and modulates many cellular functions. This molecule can be produced by enzymatic digestion of sphingomyelin, a phospholipid which has been shown to be in high concentration in a chromatin phospholipidic fraction. In order to clarify whether chromatin sphingomyelin has a role in thi...

journal_title：Biochemical and biophysical research communications

authors： Albi E,Magni MP

更新日期：1997-07-09 00:00:00

abstract：:Palmar fibromatosis is a benign fibroproliferative tumor of unknown etiology, with a high rate of recurrence after excision. The offending cells of palmar fibromatosis are myofibroblasts and the cellular origin of other myofibroblasts has previously been reported to be the bone marrow. However, further clarification o...

journal_title：Biochemical and biophysical research communications

authors： Wang JP,Hui YJ,Wang ST,Huang YC,Chiang ER,Liu CL,Chen TH,Hung SC

更新日期：2011-05-06 00:00:00

abstract：:Renin is produced from an inactive precursor, prorenin, through endoproteolytic cleavage at paired basic amino-acid residues. Using (35S)methionine-labeled prorenin, that was synthesized with Xenopus oocyte expression system, as a substrate, we have determined the tissue distribution and the nature of prorenin-convert...

journal_title：Biochemical and biophysical research communications

authors： Nakayama K,Kim WS,Hatsuzawa K,Hashiba K,Murakami K

更新日期：1989-01-31 00:00:00

abstract：:Endo-beta-1,4-xylanase X-I is a major hydrolase produced by the aleurone tissue of germinating barley grain. It was previously reported that this cytosolic enzyme is synthesized as an inactive precursor which is proteolytically processed to active forms upon its programmed cell death dependent release. We here demonst...

journal_title：Biochemical and biophysical research communications

authors： Van Campenhout S,Pollet A,Bourgois TM,Rombouts S,Beaugrand J,Gebruers K,De Backer E,Courtin CM,Delcour JA,Volckaert G

更新日期：2007-05-11 00:00:00