Abstract:
:An age-appropriate questionnaire (GASP-Q) was used to assess the frequency and severity of the gastroesophageal reflux disease (GERD) symptoms: abdominal/belly pain, chest pain/heartburn, pain after eating, nausea, burping/belching, vomiting/regurgitation, choking when eating, and difficulty swallowing, in adolescents age 12 to 16 years. The primary objective was to compare the mean composite symptom score (CSS) at week 8 with baseline after treatment with 20 or 40 mg of pantoprazole. Statistically significant (p < 0.001) improvement in CSS occurred in both groups. Safety was comparable between the 2 groups. Pantoprazole was safe, well tolerated, and effective in reducing symptoms of GERD in adolescents.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Tsou VM,Baker R,Book L,Hammo AH,Soffer EF,Wang W,Comer GM,326 Study Group.doi
10.1177/0009922806292792subject
Has Abstractpub_date
2006-10-01 00:00:00pages
741-9issue
8eissn
0009-9228issn
1938-2707pii
45/8/741journal_volume
45pub_type
杂志文章,多中心研究,随机对照试验abstract::Lactobezoar is a compact mass of undigested milk concretions located within the gastrointestinal tract. Most often found in infants, they can precipitate gastric outlet obstruction, mimicking a variety of medical and surgical conditions. A common etiology and method of cure have yet to be elucidated. A review of the l...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280104001104
更新日期:2001-11-01 00:00:00
abstract::We examined the clinical and physiological benefits of heated humidified high-flow nasal cannula (HHHFNC) in treating pediatric bronchiolitis in a general pediatric ward. Children aged 0 to 2 years, hospitalized with moderate to severe bronchiolitis, were connected to HHHFNC. Each child was evaluated at 4- to 10-hour ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819877881
更新日期:2019-12-01 00:00:00
abstract::This study compares 2 sampling methods for urine cultures in young infants. We analyzed data on urine samples obtained from 83 infants using 2 sources of urine: suprapubic bladder aspiration (SPA) and bladder catheterization. All specimens were subjected to both urinalysis and culture, and the results compared. Eighty...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815608278
更新日期:2016-08-01 00:00:00
abstract::A case study of a family referred for clarification of cultural issues illustrates how a transcultural psychiatric service developed in the pediatric hospital setting can be used to advantage. A Vietnamese family with an inherited disorder. Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome, MPS VI), resisted gene...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288902801009
更新日期:1989-10-01 00:00:00
abstract::When dealing with the management of the dying patient and his family, systematic research has been very limited. Understanding the dying child's needs, as well as his family's, is important for approprirate therapy programs. The present study investigated the mother's awareness of her child's expressed and wanted need...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287701600207
更新日期:1977-02-01 00:00:00
abstract::The paper presents clinical manifestations and results of cytogenetic examination of two patients with trisomy 8 mosaicism syndrome. The findings confirm the extreme phenotype variability of this syndrome. Both the first patient, a mentally retarded child with multiple dysmorphic changes, and the second, a 31-year-old...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288802701109
更新日期:1988-11-01 00:00:00
abstract::This article reports the case of a 3-year-old male with an elevated blood lead level. The child had a history of consuming imported lead-contaminated candies resulting in abdominal pains for which he was given a Hispanic folk remedy, called greta, by his mother. The home remedy aggravated the child's symptoms which pr...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807304385
更新日期:2008-01-01 00:00:00
abstract::Objective To identify any socioeconomic, demographic, neonatal, and perinatal factors that may be associated with failing the otoacoustic emissions (OAE) newborn hearing screen. Study Design A retrospective chart review was performed looking at hearing screens performed on 1272 newborn infants by OAE testing. Socioeco...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815615826
更新日期:2016-10-01 00:00:00
abstract::Antibiotics are widely prescribed for children with nonspecific upper respiratory tract infections, contributing to the recent emergence of resistant pneumococci. To understand the reasons for the overprescription of antibiotics, we conducted focus groups with parents and with pediatricians and family physicians to as...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803701104
更新日期:1998-11-01 00:00:00
abstract::This study was conducted to determine whether intravenous theophylline, added to inhaled albuterol and intravenous methylprednisolone, provides a clinically significant benefit in the treatment of pediatric status asthmaticus. Patients aged 2 to 10 years were randomized to receive either intravenous theophylline or pl...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992289503400905
更新日期:1995-09-01 00:00:00
abstract::A 12-hour fasting lipid profile was obtained from 88 otherwise healthy obese (BMI > or = 95%) adolescents (age 16 +/- 1 years, BMI 36 +/- 1 kg/m(2), 55 males, 33 females, 57% Hispanic, 23% African American, 19% Caucasian, 1% Asian American). About 56% of the obese adolescents exhibited lipid abnormalities based on cut...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809341076
更新日期:2010-01-01 00:00:00
abstract::OBJECTIVES. Cough, pain, and desaturation episodes in infants are often ascribed to gastroesophageal reflux, and many are empirically treated with acid suppression medications. The authors hypothesize that most of these symptoms are not related to gastroesophageal reflux. METHODS. Retrospective review of 186 combined ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811412585
更新日期:2011-12-01 00:00:00
abstract::Osteoporosis causes significant morbidity for boys with Duchenne muscular dystrophy. Corticosteroid therapy given to prolong mobility may increase the rate of osteoporosis and risk of fracture. This study of 33 boys with Duchenne muscular dystrophy determined retrospectively the incidence of vertebral fractures partic...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280304200408
更新日期:2003-05-01 00:00:00
abstract::In a patient with suppurative lymphadenitis who fails to respond to antibiotics routinely used for pyogenic adenitis, the diagnosis of tularemia should be considered if there is good evidence for recent tick or other insect exposure. A trial of streptomycin therapy may be indicated, pending culture and serology result...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287901800408
更新日期:1979-04-01 00:00:00
abstract::This study aims to evaluate the cost-benefit of vaccination services, mostly partial series administration, provided by a mobile clinic program (MCP) in Houston for children of transient and low-income families. The study included 469 patients who visited the mobile clinics on regular service days in 2 study periods i...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820908586
更新日期:2020-06-01 00:00:00
abstract::An association between the frequency of otitis media in early childhood and later hyperactivity is reported in this study. The subjects were 67 children referred to a child development clinic for evaluation of school failure. Ranging from 6 to 13 years old, all the children demonstrated specific school learning proble...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600508
更新日期:1987-05-01 00:00:00
abstract::Only five cases of subarachnoid-pleural fistula in children have been reported previously. All had a history of trauma and associated neurologic deficit which gave clue to the diagnosis. The authors present a child who presented with a massive, rapidly filling, clear pleural effusion in whom there was no neurologic de...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600807
更新日期:1987-08-01 00:00:00
abstract::The aim of this integrative review is to investigate current literature regarding family health history (FHH) taking practices, attitudes, and challenges in the pediatric outpatient setting. FHH is a known clinical tool for providers; however, there are no explicit standards for pediatric FHH collection. The integrati...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820943474
更新日期:2020-12-01 00:00:00
abstract::This study describes urban emergency department (ED) utilization and follow-up referral patterns among adolescents. ED visits for 14-19-year-old patients at an urban university hospital with adjacent adult and pediatric emergency departments during specified months in 1993 were retrospectively reviewed. A subgroup (n=...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280003900806
更新日期:2000-08-01 00:00:00
abstract::Acute pancreatitis is unusual in pediatric patients, and chronic pancreatitis is even less common. Between 1983 and 1988, we diagnosed 24 patients in late childhood and adolescence with chronic pancreatitis. Our review revealed that chronic pancreatitis presents as recurrent abdominal pain in late childhood and adoles...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289403300205
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVE:Intervention to reduce nonurgent pediatric emergency department (PED) visits over a 12-month follow-up. METHODS:Prospective, randomized, controlled trial enrolled children seen in the PED for nonurgent concerns. Intervention subjects received a structured session/handout specific to their primary care provid...
journal_title:Clinical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1177/0009922814540987
更新日期:2014-09-01 00:00:00
abstract::Bedwetting is the most common urologic complaint among children. Wetting frequency at age 7 years varies from 5% to 15%. Treatment has been multimodal: drugs to depress bladder activity, increase urethral resistance, or modulate sleep; electrophysiologic treatment; and, recently, urine production modulation. All of th...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/0009922893032001s02
更新日期:1993-07-01 00:00:00
abstract::This study evaluated the effects of Certified Child Life Specialist (CCLS) intervention on pediatric distress and pain and family satisfaction during routine peripheral intravenous (PIV) line placement in the emergency department (ED). A convenience sample of 78 children (3-13 years) requiring PIV placement for their ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818798386
更新日期:2018-11-01 00:00:00
abstract::Four children with isolated, persistent elevations of serum transaminases were investigated for hepatic disease and followed for 4 to 24 months before serum creatine kinase determinations were obtained and found to be markedly elevated. Evidence of muscle disease was obtained by close questioning, retrospectively, and...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400906
更新日期:1985-09-01 00:00:00
abstract::Few studies have described the woman who chooses breast-feeding by more than simple demographics. The purpose of our study was to characterize new mothers by their infant feeding decisions, by demographic and obstetrical data, and by sources of personal support they received during their pregnancies and in making thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900105
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Waist circumference (WC) to height ratio (WC/HT) is used as a measure of central obesity. However, the optimum ratio that will separate populations with high from low cardiovascular risk remains controversial. This investigation evaluates an optimum WC/HT value to define central obesity in children. METHODS...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814557784
更新日期:2015-06-01 00:00:00
abstract::Using questionnaires, administrative claims, and chart review data, the current study explored the impact of using an electronic medical record system to administer, score, and store the Pediatric Symptom Checklist (PSC-17) during annual pediatric well-child visits. Within a sample of 1773 Medicaid-insured outpatients...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819892038
更新日期:2020-02-01 00:00:00
abstract::Between 1979 and 1981, 22 children with osteomyelitis and/or septic arthritis were hospitalized at Soroka University Hospital. Streptococcus pneumoniae was cultured in five of the children, four of whom were under 2 years of age. In four other children under 2 years of age, Haemophilus influenzae was cultured. Staphyl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400305
更新日期:1985-03-01 00:00:00
abstract::The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500806
更新日期:1986-08-01 00:00:00
abstract::Two infants presented with growth failure and were found to have generalized osteomalacia (rickets) due to phosphate depletion from prolonged administration of an aluminum-containing antacid given for the symptoms of colic. One of the infants developed bilateral proptosis due to craniosynostosis related to the underly...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289503400202
更新日期:1995-02-01 00:00:00