Abstract:
:OBJECTIVES. Cough, pain, and desaturation episodes in infants are often ascribed to gastroesophageal reflux, and many are empirically treated with acid suppression medications. The authors hypothesize that most of these symptoms are not related to gastroesophageal reflux. METHODS. Retrospective review of 186 combined pH-multichannel intraluminal impedance studies performed in infants at Cincinnati Children's Hospital. RESULTS. Of 4159 symptoms reported 1504 (36%) were associated with reflux events (27% nonacid and 9% acid). When total number of symptoms and reflux events were taken into consideration, nonacid reflux events were as likely to be associated with a symptom as acid reflux events (P = .66). CONCLUSION. The extra-esophageal symptoms commonly attributed to gastroesophageal reflux in infants are most often not associated with a reflux event. Even though causality cannot be definitively proven, in the minority in whom a symptom association is observed, nonacid events are as likely as acid events to cause symptoms.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Garza JM,Nylund CM,Kaul Adoi
10.1177/0009922811412585subject
Has Abstractpub_date
2011-12-01 00:00:00pages
1110-5issue
12eissn
0009-9228issn
1938-2707pii
0009922811412585journal_volume
50pub_type
杂志文章abstract::This study investigates relations between language and cognitive scores in children with receptive language (RL) delay and suggests guidelines for referral for cognitive testing. This retrospective review of the test scores of 41 children, ages 17 to 76 months (mean = 37.7 months), focuses on examining associations be...
journal_title:Clinical pediatrics
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journal_title:Clinical pediatrics
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journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
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