Intravenous theophylline in pediatric status asthmaticus. A prospective, randomized, double-blind, placebo-controlled trial.

Abstract:

:This study was conducted to determine whether intravenous theophylline, added to inhaled albuterol and intravenous methylprednisolone, provides a clinically significant benefit in the treatment of pediatric status asthmaticus. Patients aged 2 to 10 years were randomized to receive either intravenous theophylline or placebo. All patients received aerosolized albuterol and intravenous methylprednisolone. There was no difference between groups in the improvement of a clinical asthma score over time, in oxygen requirement, or in the number of albuterol treatments required. Theophylline group patients experienced more nausea, emesis, and insomnia. We conclude that there is no benefit in adding theophylline to treatment with methylprednisolone and albuterol for pediatric status asthmaticus. Furthermore, there are significantly more adverse effects associated with the use of theophylline.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Bien JP,Bloom MD,Evans RL,Specker B,O'Brien KP

doi

10.1177/000992289503400905

subject

Has Abstract

pub_date

1995-09-01 00:00:00

pages

475-81

issue

9

eissn

0009-9228

issn

1938-2707

journal_volume

34

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:2009-07-01 00:00:00

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    abstract:OBJECTIVE:To compare parental report of child body image with perceived healthy weight body image in preschoolers and describe weight-counseling preferences. METHODS:Parents seeking well-child care were interviewed and asked to select images resembling: (a) their own child's current weight, (b) a healthy weight presch...

    journal_title:Clinical pediatrics

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    doi:10.1177/0009922810368288

    authors: Hernandez RG,Cheng TL,Serwint JR

    更新日期:2010-08-01 00:00:00

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992287601500713

    authors: Hankin L,Heichel GH,Botsford RA

    更新日期:1976-07-01 00:00:00

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922812470868

    authors: Ambrose CS,Toback SL

    更新日期:2013-03-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1177/000992288502400906

    authors: Rutledge J,Andersen J,Fink CW,Cook J,Strickland A

    更新日期:1985-09-01 00:00:00

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章,评审

    doi:10.1177/000992280504400702

    authors: Schwartz RH

    更新日期:2005-09-01 00:00:00

  • Utilization of Antipyretics for Nonurgent Fever in a Pediatric Emergency Department.

    abstract::This retrospective cohort study aimed to describe antipyretic use among healthy patients in a pediatric emergency department (ED) with nonurgent fever defined as: triage level 4 or 5, chief complaint fever or temperature 38°C to 39°C, and otherwise normal vital signs, and determine if antipyretic administration is ass...

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    pub_type: 杂志文章

    doi:10.1177/0009922817734356

    authors: Nelson CE,Ostapenko S,Zorc JJ,Balamuth F

    更新日期:2018-06-01 00:00:00

  • Evaluation of cefotaxime in bacterial infections.

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    pub_type: 杂志文章

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    authors: Varghese M,Khan AJ,Kumar K,Schaeffer HA,Pierro M,Evans HE

    更新日期:1984-04-01 00:00:00

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992289903800305

    authors: Grossman LK,Rich LN,Michelson S,Hagerty G

    更新日期:1999-03-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1177/000992289002900212

    authors: Ryan CF,Lowe AA,Fleetham JA

    更新日期:1990-02-01 00:00:00

  • Physician Perspectives on Decision Making for Treatment of Pediatric Sleep-Disordered Breathing.

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    pub_type: 杂志文章

    doi:10.1177/0009922817702939

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

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    更新日期:2007-06-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1986-01-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    更新日期:2008-01-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1177/000992289703600707

    authors: Sisson BA,Franco SM,Carlin WM,Mitchell CK

    更新日期:1997-07-01 00:00:00

  • Improving developmental screening among pediatricians in New Mexico: findings from the developmental screening initiative.

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    pub_type: 杂志文章

    doi:10.1177/0009922814527499

    authors: Malik F,Booker JM,Brown S,McClain C,McGrath J

    更新日期:2014-06-01 00:00:00

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    abstract::Transient cataracts in patients with insulin-dependent diabetes mellitus (IDDM) are rare and have been reported only in association with severe ketoacidosis or hyperosmolarity. We present an adolescent with transient bilateral posterior subcapsular cataracts, which developed after the recent onset of IDDM without keto...

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    pub_type: 信件

    doi:10.1177/000992289303201108

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    更新日期:1993-11-01 00:00:00

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    pub_type: 杂志文章,评审

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    更新日期:2001-11-01 00:00:00

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

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  • Taste of Clindamycin and Acetaminophen.

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章,随机对照试验

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  • Pediatric residents' perceptions of family-centered rounds as part of postgraduate training.

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    pub_type: 杂志文章

    doi:10.1177/0009922813501377

    authors: Pinto JM,Chu D,Petrova A

    更新日期:2014-01-01 00:00:00

  • Clinical features of a Dutch cohort of critically ill children due to the 2009 new influenza A H1N1 pandemic.

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    pub_type: 杂志文章,多中心研究

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    更新日期:2011-01-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:1991-07-01 00:00:00

  • A critical review of studies of newborn discharge timing.

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1177/000992289503401201

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    更新日期:1995-12-01 00:00:00

  • Nursing bottle caries: characteristics of children at risk.

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    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288902800305

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    更新日期:1989-03-01 00:00:00

  • Maternal experience of interactions with providers among mothers with milk supply concern.

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1177/000992289503400304

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    更新日期:1995-03-01 00:00:00

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