Abstract:
:The paper presents clinical manifestations and results of cytogenetic examination of two patients with trisomy 8 mosaicism syndrome. The findings confirm the extreme phenotype variability of this syndrome. Both the first patient, a mentally retarded child with multiple dysmorphic changes, and the second, a 31-year-old woman with normal IQ and hypogammaglobulinemia as a predominant sign, revealed osteoarticular anomalies. Dermatoglyphic studies in both patients were typical for trisomy 8, and correlated with deep skin furrows. The chromosomal analysis was based on two types of lymphocyte cultures: 3-day and 2-day. A decreased percentage of trisomic cells in 3-day cultures in comparison to 2-day cultures may suggest the influence of environmental factors on spontaneous elimination of trisomic cells in vitro.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Kurtyka ZE,Krzykwa B,Piatkowska E,Radwan M,Pietrzyk JJdoi
10.1177/000992288802701109subject
Has Abstractpub_date
1988-11-01 00:00:00pages
557-64issue
11eissn
0009-9228issn
1938-2707journal_volume
27pub_type
杂志文章abstract::Neonatal intensive care unit (NICU) survivors demonstrate handicapping sensorineural hearing loss up to 50 times more frequently than normal newborns, yet little is known about the etiology of the hearing loss. Theoretically, accurate identification and triage of a particular infant based on a clinical profile would b...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289503400304
更新日期:1995-03-01 00:00:00
abstract::We analyzed findings from the 2009-2010 National Survey of Children with Special Health Care Needs to identify associations between families with children and youth with special health care needs (CYSHCN) reporting adequate care coordination (CC) with family-provider relations, shared decision making (SDM), and child ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818783501
更新日期:2018-10-01 00:00:00
abstract::To examine causes of newborn hospital readmission and morbidity related to early nursery discharge, we reviewed the charts of 664 newborns readmitted from home under the age of 15 days, between 1993 and 1995. Early discharge (ED) was defined as nursery length of stay of < or = 2 days. Morbidity related to ED: onset of...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803701003
更新日期:1998-10-01 00:00:00
abstract::Although trauma undertriage has been widely discussed in the literature, undertriage in the pediatric trauma population remains understudied. Using the 2009-2013 Nationwide Emergency Department Sample, we assessed the national undertriage rate in pediatric major trauma patients (age ≤16 years and injury severity score...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817709553
更新日期:2017-08-01 00:00:00
abstract::Psychiatric referral is an important aspect of clinical pediatric practice. This paper discusses referral to a family-oriented psychiatrist of difficult families with children who have an acute or chronic psychosomatic complaint. It is the responsibility of primary care physicians to develop facility in making psychia...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288302200301
更新日期:1983-03-01 00:00:00
abstract::The duration of hospitalization for newborns has declined dramatically, driven by efforts to control health-care costs as well as by efforts to demedicalize childbirth. In order to determine the clinical basis for this practice, the quality of the published literature on discharge timing was analyzed. Thirteen experim...
journal_title:Clinical pediatrics
pub_type: 杂志文章,meta分析
doi:10.1177/000992289503401201
更新日期:1995-12-01 00:00:00
abstract::The frequency of accessory nipples in black Americans is almost eight times greater than in white European patients. Association of a wide range of abnormalities with supernumerary nipples in whites has, thus far, not been our experience in black Americans. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288202100107
更新日期:1982-01-01 00:00:00
abstract::Liquid antibiotics are often substantially more expensive than their pill counterparts, representing an opportunity for substantial cost reductions. Children can be taught to swallow pills at about age 6 years. The objective of this study was to calculate the potential cost saved by replacing liquid antibiotics with c...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818774340
更新日期:2018-10-01 00:00:00
abstract::A 12-hour fasting lipid profile was obtained from 88 otherwise healthy obese (BMI > or = 95%) adolescents (age 16 +/- 1 years, BMI 36 +/- 1 kg/m(2), 55 males, 33 females, 57% Hispanic, 23% African American, 19% Caucasian, 1% Asian American). About 56% of the obese adolescents exhibited lipid abnormalities based on cut...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809341076
更新日期:2010-01-01 00:00:00
abstract::A 4-year-old boy with transient erythroblastopenia of childhood (TEC) presented with papilledema and transient hemiparesis. Upon spontaneous hematologic recovery, the papilledema resolved. It is concluded that TEC, like other forms of anemia, may present with papilledema and even focal neurologic deficit, from which s...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500510
更新日期:1986-05-01 00:00:00
abstract::Rotavirus gastroenteritis primarily affects children younger than 5 years of age and is the leading cause of diarrhea-related hospitalizations worldwide. The substantial morbidity associated with this disease and the major burden on healthcare resources underscore the need for an effective vaccine. Two recently develo...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808314903
更新日期:2008-07-01 00:00:00
abstract::Bacteremia in patients with cystic fibrosis (CF) has not been previously reported, a fact probably attributable to activated systemic immunity in the presence of chronic bronchopulmonary infection. We have observed two CF patients under a year of age with documented bacteremia, and a teen-aged patient with autopsy evi...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001901106
更新日期:1980-11-01 00:00:00
abstract:OBJECTIVE:Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a major contributor to neonatal hyperbilirubinemia, yet newborn screening for this disorder in the United States is not standard practice. We surveyed pediatric providers regarding a novel newborn G6PD screening program successfully implemented in 2007 at...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814557786
更新日期:2015-06-01 00:00:00
abstract::The need for exchange transfusion was analyzed retrospectively using several different methods (total bilirubin binding capacity, birth weight, plasma protein level, and two published charts). These predictive methods were applied to 175 jaundiced infants for whom all the data were available and to 19 infants who were...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288302200801
更新日期:1983-08-01 00:00:00
abstract::The authors administered an abbreviated revision of a previously field-tested, self-administered, brief screening test (the 30-item Drug and Alcohol Problem Quick Screen) to 355 consecutive middle-class adolescent patients seen at a five-pediatrician group practice setting. Ninety-six percent (341) of the subjects com...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900106
更新日期:1990-01-01 00:00:00
abstract::Based on a retrospective 5-year medical record review, this study characterizes factors associated with patients discharged against medical advice (AMA) from a tertiary pediatric emergency department (ED) and compares rates of return to the ED and admission to the hospital with those of patients routinely discharged. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808323109
更新日期:2009-04-01 00:00:00
abstract::Lactobezoar is a compact mass of undigested milk concretions located within the gastrointestinal tract. Most often found in infants, they can precipitate gastric outlet obstruction, mimicking a variety of medical and surgical conditions. A common etiology and method of cure have yet to be elucidated. A review of the l...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280104001104
更新日期:2001-11-01 00:00:00
abstract::This study aims to explore the changes in endothelin-1 (ET-1), plasma neuropeptide Y, and calcitonin gene-related peptide (CGRP) in child patients before and after operation. A total of 80 child patients with congenital heart disease (CHD) complicated with pulmonary hypertension (PH) were enrolled and divided into con...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820948261
更新日期:2021-01-01 00:00:00
abstract::Transient synovitis of the hip is a common cause of hip pain in children. The etiology of transient synovitis of the hip is unknown. Lyme arthritis is characterized by brief, often recurrent episodes of oligoarthritis. Lyme arthritis most often affects a single knee, but hip involvement is uncommon. This report descri...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808318337
更新日期:2008-10-01 00:00:00
abstract::A recent study has claimed that children who do not have gingivitis do not have bacteremia following dental manipulations and that these children do not require antibiotic prophylaxis. Postoperative blood cultures from 53 children and adolescents with and without gingivitis drawn within ten minutes of elevation of the...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章
doi:10.1177/000992287501400609
更新日期:1975-06-01 00:00:00
abstract::An eight-year-old boy developed staphylococcal endocarditis. He was treated initially with nafcillin and gentamicin, but he remained febrile. The minimum bactericidal concentration (MBC) of nafcillin was 130 times the minimum inhibitory concentration (MIC). Following the addition of rifampin to the antibiotic regimen,...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288202100414
更新日期:1982-04-01 00:00:00
abstract::Bullying is a serious issue for adolescents, with health consequences both at the time of victimization and later on in adulthood. Aggression in the media is an area that has been explored as a contributing factor to bullying behavior. This study aims to determine if the incidence of aggression in popular television s...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815614353
更新日期:2016-10-01 00:00:00
abstract::Few studies have described the woman who chooses breast-feeding by more than simple demographics. The purpose of our study was to characterize new mothers by their infant feeding decisions, by demographic and obstetrical data, and by sources of personal support they received during their pregnancies and in making thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900105
更新日期:1990-01-01 00:00:00
abstract::Eleventh- and 6th-grade students from an urban public school district were surveyed concerning vaccination outside the traditional medical home. Survey response rates were 50% for 11th- and 73% for 6th-grade students. Seventy-two percent of 11th-grade students reported that public health clinics were definitely or pro...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813475703
更新日期:2013-04-01 00:00:00
abstract::Clinic-based social needs screening has been associated with increased access to social services and improved health outcomes. Using a pragmatic study design in an urban pediatric practice, we used logistic regression to identify factors associated with successful social service uptake. From December 2017 to November ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820908589
更新日期:2020-06-01 00:00:00
abstract::This study investigates relations between language and cognitive scores in children with receptive language (RL) delay and suggests guidelines for referral for cognitive testing. This retrospective review of the test scores of 41 children, ages 17 to 76 months (mean = 37.7 months), focuses on examining associations be...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808323108
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:The rate at which pediatricians promote smoking cessation in clinical settings is low. The literature demonstrates that interventions paired with tangible health promotion materials may significantly increase screening rates to the pediatric office. The aim of this study was to investigate whether the additi...
journal_title:Clinical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1177/0009922816684607
更新日期:2017-10-01 00:00:00
abstract::This study examines primary care provider (PCP) experiences with the initial parental disclosure of cystic fibrosis (CF) newborn screening (NBS) results in order to identify methods to improve parent-provider communication during the CF NBS process. PCPs of infants who received positive CF NBS results participated in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814545619
更新日期:2015-01-01 00:00:00
abstract::Childhood thyrotoxicosis is not an uncommon illness, but there is a considerable relapse rate in these patients on medical treatment. An attempt is made in this study to identify those markers that are predictive of a tendency to relapse in childhood thyrotoxicosis. A total of 32 patients with Graves disease were incl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600306
更新日期:1987-03-01 00:00:00
abstract::Our primary objective was to compare parents of infants cared for in newborn intensive care units (NICUs) and infants cared for in well-baby ("general") nurseries with regard to knowledge and practice of safe sleep practices/sudden infant death syndrome risk reduction measures and guidelines. Our secondary objective w...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813506038
更新日期:2013-11-01 00:00:00