Isolated low HDL cholesterol emerges as the most common lipid abnormality among obese adolescents.

Abstract:

:A 12-hour fasting lipid profile was obtained from 88 otherwise healthy obese (BMI > or = 95%) adolescents (age 16 +/- 1 years, BMI 36 +/- 1 kg/m(2), 55 males, 33 females, 57% Hispanic, 23% African American, 19% Caucasian, 1% Asian American). About 56% of the obese adolescents exhibited lipid abnormalities based on cutoff points established by American Heart Association (AHA) guidelines, and about 57% exhibited lipid abnormalities based on percentile values established by the Lipid Research Clinic Pediatric Prevalence Study. Isolated low high-density lipoprotein-cholesterol (HDL-C) was the most common abnormality (43% based on AHA, 36% based on the Lipid Research Clinic Pediatric Prevalence Study) among the obese adolescents with lipid disorders. While there was no significant statistical difference (SSD) between genders in the levels of total cholesterol and low-density lipoprotein-cholesterol (LDL-C), triglyceride (TG) levels were significantly higher (P = .003) in males (120 +/- 11 mg/dL) than in females (81 +/- 7 mg/dL), and levels of HDL-C were significantly higher (P = .006) in females (42 +/- 2 mg/dL) than in males (35 +/- 1 mg/dL). There was no SSD between races in total cholesterol and LDL-C levels. TG levels were significantly lower in African-American participants (81 +/- 9 mg/ dL) compared with levels in Caucasian participants (117 +/- 15 mg/dL, P

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Harel Z,Riggs S,Vaz R,Flanagan P,Harel D

doi

10.1177/0009922809341076

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

29-34

issue

1

eissn

0009-9228

issn

1938-2707

pii

0009922809341076

journal_volume

49

pub_type

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