Abstract:
:This study aims to explore the changes in endothelin-1 (ET-1), plasma neuropeptide Y, and calcitonin gene-related peptide (CGRP) in child patients before and after operation. A total of 80 child patients with congenital heart disease (CHD) complicated with pulmonary hypertension (PH) were enrolled and divided into control group (n = 40, conservative treatment for various reasons) and observation group (n = 40, active preoperative preparation and timely operative intervention) according to different treatments. There were positive correlations between systolic pulmonary arterial pressure (sPAP) and ET-1, plasma neuropeptide Y, while negative correlation between sPAP and CGRP. In conclusion, our data demonstrate that the levels of ET-1, plasma neuropeptide Y, and CGRP in PH-CHD were significantly changed after interventions, which provides new leads as alternative biomarkers to assess the efficacy of treatments against PH-CHD.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Liu Z,Zhang M,Huo Q,Zhu Tdoi
10.1177/0009922820948261subject
Has Abstractpub_date
2021-01-01 00:00:00pages
56-63issue
1eissn
0009-9228issn
1938-2707journal_volume
60pub_type
杂志文章abstract:OBJECTIVE:The etiology of an apparent life-threatening event (ALTE) has been attributed to a wide range of causes. Physicians rely on caregiver narratives, which are often unreliable given the distressing nature of the event, which in turn leads to variation in the evaluation and management. The objective of this study...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811419495
更新日期:2012-02-01 00:00:00
abstract::This study was conducted to determine if culture confirmation is needed for a negative rapid antigen detection test. Data on 18,509 tests done in patients younger than 18 years old were reviewed. Of the 14,167 (76.5%) that were negative, 968 (6.8%) were associated with positive cultures. No significant seasonal variat...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/0009922806290219
更新日期:2007-04-01 00:00:00
abstract::Although common, little is known about the characteristics and management of undifferentiated abdominal pain (UAP) in the pediatric emergency department (ED). This study was a 12-month retrospective study for "abdominal pain" ED visits. Patients without an identifiable diagnosis were categorized as "UAP," while others...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819867459
更新日期:2019-10-01 00:00:00
abstract::Our primary objective was to compare parents of infants cared for in newborn intensive care units (NICUs) and infants cared for in well-baby ("general") nurseries with regard to knowledge and practice of safe sleep practices/sudden infant death syndrome risk reduction measures and guidelines. Our secondary objective w...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813506038
更新日期:2013-11-01 00:00:00
abstract::A scoring method was developed to assess severity of stool retention using plain abdominal radiographs. To determine whether the technique was clinically valid in identifying chronic stool retention, the method was used to evaluate films taken of children with known stool retention before and after therapy. The method...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287901801103
更新日期:1979-11-01 00:00:00
abstract::The escalation of the opioid crisis has led to an increase in the treatment of opioid use disorder. In particular, recent legislation has allowed for office-based treatment with buprenorphine, a partial µ-opioid agonist that is believed to be safer than methadone due to a ceiling effect on respiratory depression in ad...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/0009922819829038
更新日期:2019-06-01 00:00:00
abstract::Topical application of ocular drugs may cause serious adverse ocular or systemic side effects. Children are at greater risk for systemic side effects because ocular dosing is not weight-adjusted, and infants are especially vulnerable as a consequence of the inability to efficiently metabolize the drug, and/or an immat...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280404300114
更新日期:2004-01-01 00:00:00
abstract::Few studies have described the woman who chooses breast-feeding by more than simple demographics. The purpose of our study was to characterize new mothers by their infant feeding decisions, by demographic and obstetrical data, and by sources of personal support they received during their pregnancies and in making thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900105
更新日期:1990-01-01 00:00:00
abstract::The General Academic Pediatrician (GAP) may act as a consultant to both primary care pediatricians and tertiary care subspecialists. The authors surveyed a consultation service staffed by three GAP's in a tertiary care children's hospital. The service was financially successful and generated new sources of referrals f...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288802701203
更新日期:1988-12-01 00:00:00
abstract::Clinic-based social needs screening has been associated with increased access to social services and improved health outcomes. Using a pragmatic study design in an urban pediatric practice, we used logistic regression to identify factors associated with successful social service uptake. From December 2017 to November ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820908589
更新日期:2020-06-01 00:00:00
abstract::Infants with extracardiac anomalies or malformation syndromes frequently have associated cardiovascular malformations. Knowledge of these predictable patterns of associations allow rapid diagnosis and treatment of these infants. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300303
更新日期:1984-03-01 00:00:00
abstract:BACKGROUND:Often diapers are not changed after infants pass urine. AIM:To define the association between the frequency of changing diapers and urinary tract infection (UTI) in infants. METHODS:Urine samples were tested in 131 infants (aged from 2 months to 2.5 years) who had a temperature > or =38 degrees C. The auth...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922808320696
更新日期:2009-01-01 00:00:00
abstract::This article discusses a 4-year-old girl who displayed behavioral symptoms consistent with posttraumatic stress disorder. She was recently placed in foster care due to emotional and physical neglect. During her clinic visit, she disclosed being sexually abused by her father with a knife. Results of her general and ano...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807304365
更新日期:2008-01-01 00:00:00
abstract::Eleventh- and 6th-grade students from an urban public school district were surveyed concerning vaccination outside the traditional medical home. Survey response rates were 50% for 11th- and 73% for 6th-grade students. Seventy-two percent of 11th-grade students reported that public health clinics were definitely or pro...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813475703
更新日期:2013-04-01 00:00:00
abstract::Twenty-two pediatric residents and 31 medical students viewed the Play Nicely program. The Play Nicely program is a multimedia program that teaches health care professionals how to counsel parents to use positive parenting and disciplining strategies in response to early childhood aggression. Health care professionals...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816667313
更新日期:2016-10-01 00:00:00
abstract::Of 1045 children admitted with gastroenteritis over a 12-month period and studied retrospectively, serum sodium level was tested in 802. Sixty patients (7.5%) had hypernatremic dehydration (HD). The peak incidence of HD, the highest serum sodium levels, and the worst outcome were all encountered in infants under the a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300501
更新日期:1984-05-01 00:00:00
abstract::A case of cystic fibrosis presenting as a right lower quadrant mass in a five-year-old white female is presented. At laparotomy, a mucoid, impacted appendix was found which microscopically suggested the diagnosis of cystic fibrosis. Cystic fibrosis must be added to conditions presenting with abdominal masses. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287501400913
更新日期:1975-09-01 00:00:00
abstract::Few tools are available to pediatricians for tracking and monitoring disability status in children. We describe the conceptual basis and pilot use of the Functional Independence Measure for Children (WeeFIM). Our pilot use of this instrument in children with limb deficiency, Down's syndrome, spina bifida, cerebral pal...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992289403300708
更新日期:1994-07-01 00:00:00
abstract::Fifty-eight growth hormone (hGH) deficient adults who had received long-term hGH therapy and their families were contacted to assess their past and current status regarding peer relationships, educational and vocational achievements, and self-concepts. Both heterosexual and same-sex peer relationships were reported as...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500103
更新日期:1986-01-01 00:00:00
abstract::An eight-year-old boy developed staphylococcal endocarditis. He was treated initially with nafcillin and gentamicin, but he remained febrile. The minimum bactericidal concentration (MBC) of nafcillin was 130 times the minimum inhibitory concentration (MIC). Following the addition of rifampin to the antibiotic regimen,...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288202100414
更新日期:1982-04-01 00:00:00
abstract::The authors describe 4 first rib fractures in 3 infants, highlighting the difficulty in detecting first rib fractures on skeletal survey. All 4 fractures were the result of physical abuse. A literature search does not find a case of first rib fracture in a healthy infant that is not the result of child abuse. The diag...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811430343
更新日期:2012-05-01 00:00:00
abstract::Although pediatricians are increasingly aware of the problem of undernutrition in children with neurologic disabilities, many of these children remain poorly nourished despite prolonged attempts at oral feedings. We studied the effects of tube feeding on such children, using either nasogastric (NG) or gastrostomy (GT)...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289403300608
更新日期:1994-06-01 00:00:00
abstract::Bullying is a serious issue for adolescents, with health consequences both at the time of victimization and later on in adulthood. Aggression in the media is an area that has been explored as a contributing factor to bullying behavior. This study aims to determine if the incidence of aggression in popular television s...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815614353
更新日期:2016-10-01 00:00:00
abstract::Telemedicine has been shown to be effective for rural populations, but little is reported on pediatric obesity care via telemedicine in urban settings. This study aims to assess feasibility and acceptability of multidisciplinary pediatric obesity care via telemedicine within the same metropolitan area in terms of info...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815594359
更新日期:2016-03-01 00:00:00
abstract::This article describes ( a) parent questions about ADHD (attention deficit/hyperactivity disorder), ( b) parent Internet use to seek ADHD information, and ( c) associations between type of Internet access and ADHD information-seeking. Seventy parents of children (ages 7-17 years) with ADHD completed questionnaires aft...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/0009922817691821
更新日期:2018-01-01 00:00:00
abstract::Ninety low socioeconomic adolescent females (aged 16-22 years, means 18.6 years) were screened for rubella immunity using a rubella IgG enzyme immunoassay. Data concerning past immunizations (with documentation, if possible), prior rubella disease, and previous pregnancies were gathered through direct interviews. Resu...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400705
更新日期:1985-07-01 00:00:00
abstract::Nursing bottle carries is a pattern of extensive decay in newly erupted maxillary incisors. We examined nutritional, demographic, and behavioral characteristics of children with this condition and age/sex-matched controls, generating a profile of factors associated with increased risk for the development of this disea...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288902800305
更新日期:1989-03-01 00:00:00
abstract::A 6-year-old girl with sickle cell disease was admitted to the hospital with the diagnosis of the acute chest syndrome. The laboratory findings and the radionuclear lung scan supported a diagnosis of pulmonary infarction rather than pneumonia. She improved with intravenous fluids, oxygen, penicillin, and theophylline....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502401209
更新日期:1985-12-01 00:00:00
abstract::This study analyzed parental perception of the impact of diarrhea on quality of life of their children. A standardized questionnaire was completed by 2023 parents in Germany with children with diarrhea who were younger than 2 years old. Parents stated the most worrying aspects of diarrhea. A health score was measured ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922807310933
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:Waist circumference (WC) to height ratio (WC/HT) is used as a measure of central obesity. However, the optimum ratio that will separate populations with high from low cardiovascular risk remains controversial. This investigation evaluates an optimum WC/HT value to define central obesity in children. METHODS...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814557784
更新日期:2015-06-01 00:00:00