Abstract:
:Childhood thyrotoxicosis is not an uncommon illness, but there is a considerable relapse rate in these patients on medical treatment. An attempt is made in this study to identify those markers that are predictive of a tendency to relapse in childhood thyrotoxicosis. A total of 32 patients with Graves disease were included in the study. Several features were correlated with a tendency to relapse. Of these features, sex, family history, and antibody status were not significantly correlated to relapse. However, of 17 patients with goiter size two times normal or larger, 16 relapsed in comparison with seven relapses of 15 patients with goiter size less than two times normal (p = 0.0039). Of eight patients without ophthalmopathy, only two relapsed, while 21 patients of 24 patients with ophthalmopathy, relapsed (p = 0.002). Of 13 patients with serum thyroxine levels below 20 mcg/dl, six relapsed; of the 19 patients with serum thyroxine levels above 20 mcg/dl, 17 relapsed (p = 0.039). Among 24 patients with a previous relapse, only one achieved a remission with a second course of treatment. The remaining 23 patients had recurrent relapses. Hence it was found that goiter size, presence of ophthalmopathy, total thyroxine levels, and a previous relapse correlated significantly with a further relapse.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Tan SH,Lee BW,Wong HB,Uma Rdoi
10.1177/000992288702600306subject
Has Abstractpub_date
1987-03-01 00:00:00pages
136-9issue
3eissn
0009-9228issn
1938-2707journal_volume
26pub_type
杂志文章abstract::A 13-year old boy with acute lymphoblastic leukemia on chemotherapy developed neutropenia and acute cellulitis progressing to fulminating septicemia due to Pseudomonas pseudomallei. Septicemic melioidosis should be considered in the differential diagnosis of a febrile illness in children who are susceptible to infecti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001901012
更新日期:1980-10-01 00:00:00
abstract:BACKGROUND:Ethanol lock therapy (ELT) with systemic antimicrobial therapy is a promising therapy for catheter-related infection (CRI). The impact of ELT timing on treatment efficacy and costs is unknown. PROCEDURES:A prospective study was conducted in the Hematology/Oncology Unit at the Children's Hospital of Michigan...
journal_title:Clinical pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1177/0009922817717327
更新日期:2018-03-01 00:00:00
abstract::The effects of breast feeding in the early months of life on such clinical phenomena as the rate of weight gain, linear growth, frequency of office visits, phone calls and types of clinical morbidity encountered in office practice during the 1st year of the infant's life were examined. The practice was located in a s...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287201100109
更新日期:1972-01-01 00:00:00
abstract::A comprehensive program was founded in 1982 to provide adolescents with prenatal and family planning care. The program's impact through its first five years of operation on medical aspects of pregnancy course and fetal outcome will be the subject of a separate report. This study examines subsequent maternal and infant...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289103000508
更新日期:1991-05-01 00:00:00
abstract::According to the National Health and Nutrition Examination Survey in 2007, nearly half of all American children are either overweight or obese. Retrospective chart review identified patients with the diagnostic codes for overweight, obese, and/or excessive weight gain. Inclusion criteria were current age between 2 and...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809359418
更新日期:2010-07-01 00:00:00
abstract::Eighty children with acute otitis media (AOM) were prospectively studied to determine the correlation and clinical usefulness of nasopharyngeal (NP), conjunctival (CONJ), and middle ear fluid (MEF) cultures. NP cultures correlated more accurately with MEF (p less than 0.01) than did CONJ cultures (p less than 0.05) fo...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500205
更新日期:1986-02-01 00:00:00
abstract::The lead content of paint on wooden handles of kitchen utensils ranged from 0 to 9.7 per cent (97,000 ppm). Yellow paint showed the highest concentration of lead followed by green and red colors. The values of lead often exceeded the legal limit on toys and paint for use indoors. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287601500713
更新日期:1976-07-01 00:00:00
abstract::Eleventh- and 6th-grade students from an urban public school district were surveyed concerning vaccination outside the traditional medical home. Survey response rates were 50% for 11th- and 73% for 6th-grade students. Seventy-two percent of 11th-grade students reported that public health clinics were definitely or pro...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813475703
更新日期:2013-04-01 00:00:00
abstract::Childhood celiac disease (CD) is considered rare in the United States. Consequently there are few data concerning its clinical presentation. A validated questionnaire was distributed to families of children with CD. One hundred forty-one children with biopsy-proven CD were included in the study. We found significant d...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400309
更新日期:2005-04-01 00:00:00
abstract::This study was done to evaluate the spectrum of diagnoses and identify risk factors for significant kidney disease in asymptomatic children with proteinuria and/or microhematuria detected by routine urinalysis. Clinical and laboratory data were obtained by retrospective chart review of 239 patients referred to a terti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400105
更新日期:2005-01-01 00:00:00
abstract::Although pediatricians are increasingly aware of the problem of undernutrition in children with neurologic disabilities, many of these children remain poorly nourished despite prolonged attempts at oral feedings. We studied the effects of tube feeding on such children, using either nasogastric (NG) or gastrostomy (GT)...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289403300608
更新日期:1994-06-01 00:00:00
abstract::An asymptomatic child with a murmur can be challenging practice management conundrum. Some providers refer all patients with a "new" murmur to a cardiologist, likely resulting in excessive resource utilization and parental anxiety. This study examines whether the prevalence of significant cardiac pathology differs in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816656623
更新日期:2017-04-01 00:00:00
abstract::Topical application of ocular drugs may cause serious adverse ocular or systemic side effects. Children are at greater risk for systemic side effects because ocular dosing is not weight-adjusted, and infants are especially vulnerable as a consequence of the inability to efficiently metabolize the drug, and/or an immat...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280404300114
更新日期:2004-01-01 00:00:00
abstract::This study examines primary care provider (PCP) experiences with the initial parental disclosure of cystic fibrosis (CF) newborn screening (NBS) results in order to identify methods to improve parent-provider communication during the CF NBS process. PCPs of infants who received positive CF NBS results participated in ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814545619
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:To describe the time and actions on 3 key health topics during health supervision (HS) visits of children aged 0 to 1 years. METHOD:HS visits were observed at 5 offices. Parents provided demographics and children's measurements were obtained. Using special computer software, visits were observed for frequenc...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809337530
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVE:To assess the predictors of attrition from a clinical pediatric obesity treatment program. METHODS:We evaluated 2- through 20-year-old patients first seen at the Duke University Healthy Lifestyles Program between October 2006 and December 2008. We assessed the predictors of early dropout (not returning for a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812458355
更新日期:2012-12-01 00:00:00
abstract::Between 1979 and 1981, 22 children with osteomyelitis and/or septic arthritis were hospitalized at Soroka University Hospital. Streptococcus pneumoniae was cultured in five of the children, four of whom were under 2 years of age. In four other children under 2 years of age, Haemophilus influenzae was cultured. Staphyl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400305
更新日期:1985-03-01 00:00:00
abstract::To compare parental compliance with after-hours triage advice provided by telephone advice nurses and on-call pediatricians, a randomized controlled trial was undertaken at a university general pediatrics practice that enrolled parents or guardians calling for after-hours advice. Advice calls were randomized to a call...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992280304200707
更新日期:2003-09-01 00:00:00
abstract::Four neonates with adrenal hemorrhage are presented. The clinical manifestations included most often an abdominal mass but also anemia, jaundice, hypotension, bluish discoloration of the scrotum, and abdominal calcification. The diagnosis was established in each case upon abdominal sonographic findings. The review of ...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280104001002
更新日期:2001-10-01 00:00:00
abstract::A case presentation of a newborn infant with intermittent, complete airway obstruction secondary to a pedunculated nasopharyngeal dermoid is presented. The differential diagnosis of obstructing nasopharyngeal lesions of the neonatal period is discussed, and an organized management strategy is proposed. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289203100109
更新日期:1992-01-01 00:00:00
abstract::Two infants presented with growth failure and were found to have generalized osteomalacia (rickets) due to phosphate depletion from prolonged administration of an aluminum-containing antacid given for the symptoms of colic. One of the infants developed bilateral proptosis due to craniosynostosis related to the underly...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289503400202
更新日期:1995-02-01 00:00:00
abstract::The duration of hospitalization for newborns has declined dramatically, driven by efforts to control health-care costs as well as by efforts to demedicalize childbirth. In order to determine the clinical basis for this practice, the quality of the published literature on discharge timing was analyzed. Thirteen experim...
journal_title:Clinical pediatrics
pub_type: 杂志文章,meta分析
doi:10.1177/000992289503401201
更新日期:1995-12-01 00:00:00
abstract::We assessed the relationship between breastfeeding and antimicrobial use in the first year of life in healthy infants by surveying a military population of healthy term infants with questionnaires obtained at the 6-month and 12-month well-baby visits. Breastfed (BF) babies spent 48% as much time receiving antimicrobia...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280404300708
更新日期:2004-09-01 00:00:00
abstract::The AAP has alerted pediatricians to the importance of safe sleep environment for infants. The elements of a safe sleep environment include supine sleep position, safe crib, and avoidance of smoke exposure, soft bedding, and overheating. With the Back to Sleep campaign, prone sleeping among all U.S. infants has decrea...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280204100603
更新日期:2002-07-01 00:00:00
abstract::This study presents the characteristics of 20 children (17 female) with NIDDM who required oral hypoglycemic agent (OHA) therapy. A family history of NIDDM was present in 55%. None had islet cell antibodies (ICA) or glutamic acid decarboxylase (GAD) antibodies. Tolbutamide was the drug of choice; glibenclamide was int...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803700209
更新日期:1998-02-01 00:00:00
abstract::This study was undertaken to evaluate trends and toxicity of pediatric methylphenidate exposures; 1993 to 1999 national poison center data were analyzed. There were 12,917 exposures, increasing from 927 in 1993 to 2,445 in 1999. The majority of children during the entire study period experienced no effect (60.3%) or m...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280304200210
更新日期:2003-03-01 00:00:00
abstract::Iron poisoning was a leading cause of pediatric morbidity and mortality. We sought to assess whether the removal of strict iron packaging requirements in 2003 resulted in an increase in iron-related morbidity and mortality in pediatric exposures. We performed a retrospective cohort study utilizing the National Poison ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819901010
更新日期:2020-05-01 00:00:00
abstract:INTRODUCTION:The American Academy of Pediatrics recommends that pediatricians promote smoking cessation among caregivers at every visit. Currently, there are inconsistencies between recommendations and clinical practice. This study aims to compare results generated from 3 intervention methods on the rate at which pedia...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/0009922816688261
更新日期:2018-01-01 00:00:00
abstract::The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500806
更新日期:1986-08-01 00:00:00
abstract::Helicobacter pylori (H. pylori) is responsible for one of the most frequently encountered infectious diseases worldwide. H. pylori infection can lead to the development of gastritis and peptic ulcer disease. The presence of H. pylori in the human stomach also represents an increased risk for gastric cancer and gastric...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992289603500401
更新日期:1996-04-01 00:00:00