Rickets secondary to phosphate depletion. A sequela of antacid use in infancy.

Abstract:

:Two infants presented with growth failure and were found to have generalized osteomalacia (rickets) due to phosphate depletion from prolonged administration of an aluminum-containing antacid given for the symptoms of colic. One of the infants developed bilateral proptosis due to craniosynostosis related to the underlying metabolic bone disease. The chronic use of aluminum-containing antacids in infants has potential risk for the growing skeleton and is not innocuous. Therefore, antacid therapy should be used in low doses and very cautiously, with routine monitoring of serum calcium and phosphorus in children taking medications which reduce gastrointestinal phosphate absorption.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Pivnick EK,Kerr NC,Kaufman RA,Jones DP,Chesney RW

doi

10.1177/000992289503400202

subject

Has Abstract

pub_date

1995-02-01 00:00:00

pages

73-8

issue

2

eissn

0009-9228

issn

1938-2707

journal_volume

34

pub_type

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