Abstract:
BACKGROUND:Ethanol lock therapy (ELT) with systemic antimicrobial therapy is a promising therapy for catheter-related infection (CRI). The impact of ELT timing on treatment efficacy and costs is unknown. PROCEDURES:A prospective study was conducted in the Hematology/Oncology Unit at the Children's Hospital of Michigan. Patients with suspected CRI were randomized to Preemptive ELT arm or Rescue ELT arm after positive culture. RESULTS:Five cases in Preemptive arm and 9 in Rescue arm had a confirmed CRI. All cases cleared infection with line salvage with no adverse events due to ELT or recurrence within 14 days. Our data showed a trend toward 36% reduction in average hospital costs and 40% reduction in average length of stay in Preemptive arm over Rescue arm. CONCLUSION:Although a small study, our data on preemptive ELT with systemic antimicrobial therapy suggest a potentially important treatment strategy in reducing length of stay as well as hospital costs.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
McGrath E,Du W,Rajpurkar Mdoi
10.1177/0009922817717327subject
Has Abstractpub_date
2018-03-01 00:00:00pages
285-293issue
3eissn
0009-9228issn
1938-2707journal_volume
57pub_type
杂志文章,随机对照试验abstract::Over-the-counter cold remedies are widely used for symptomatic relief of upper respiratory tract infections. The safety of these drugs is not well established in infants and their efficacy is questionable. Our aim was to study the attitude of family physicians and pediatricians toward the use of cold remedies in infan...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806295281
更新日期:2006-11-01 00:00:00
abstract::The differential leukocyte count was studied within the first 24 hours of life in 115 infants of diabetic mothers (IDMs) appropriate for gestational age (AGA), 16 IDMs large for gestational age (LGA), 104 infants of non-diabetic mothers (INM's) AGA, and 22 INMs-LGA. A significant "shift to the left" was found in IDM's...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288602500806
更新日期:1986-08-01 00:00:00
abstract::The purpose of the current study was to develop syndrome-specific standardized growth curves for growth hormone-treated Prader-Willi syndrome (PWS) individuals aged 0 to 18 years. Anthropometric growth-related measures were obtained on 171 subjects with PWS who were treated with growth hormone for at least 40% of thei...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922815617973
更新日期:2016-09-01 00:00:00
abstract::In many countries, ibuprofen is available only in oral formulations. The authors aimed to investigate parental satisfaction and possible adverse reactions among children receiving newly marketed ibuprofen suppositories, prior to their arrival at the pharmaceutical points of distribution. Children needing antipyretic m...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922810384847
更新日期:2011-03-01 00:00:00
abstract::We studied 133 asthmatic children in the emergency room who were aged 4 to 17 years and who were not receiving ongoing training in pulmonary function testing, to determine whether spirometry correlated with the outcome of the emergency treatment of the acute attack and with relapse during the next four days. A clinica...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300203
更新日期:1984-02-01 00:00:00
abstract::Positive newborn screening (NBS) results cause significant parental distress, but little is known about how parents find out about children's screening results and what they are told. This qualitative, exploratory study reports on parents' perceptions of the initial communication of NBS results. Participants included ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922812446011
更新日期:2012-08-01 00:00:00
abstract::Childhood thyrotoxicosis is not an uncommon illness, but there is a considerable relapse rate in these patients on medical treatment. An attempt is made in this study to identify those markers that are predictive of a tendency to relapse in childhood thyrotoxicosis. A total of 32 patients with Graves disease were incl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600306
更新日期:1987-03-01 00:00:00
abstract::When evaluating a school-aged patient, particularly for such issues as attention deficit disorder, or learning disabilities, health-care providers are encouraged to appraise children's school performance. Although some clinicians seek teachers' comments, recent research suggests that teachers' appraisals have limited ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280204100909
更新日期:2002-11-01 00:00:00
abstract::Clinic-based social needs screening has been associated with increased access to social services and improved health outcomes. Using a pragmatic study design in an urban pediatric practice, we used logistic regression to identify factors associated with successful social service uptake. From December 2017 to November ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820908589
更新日期:2020-06-01 00:00:00
abstract::The Bronx Ongoing Pediatric Screening (BOPS) project sought to improve screening for sexual activity and sexually transmitted infections (gonorrhea and chlamydia [GCC] and HIV) in a primary care network, employing a modified learning collaborative, real-time clinical data feedback to practices, improvement coaching, a...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
doi:10.1177/0009922817733702
更新日期:2018-07-01 00:00:00
abstract::As clinicians, pediatricians need to be cognizant of the how the principles of equity, social justice, and children's rights help to inform and guide us as we strive for the health and well being of all children. Children of the world are frequently the most vulnerable global citizens facing poverty, displacement, and...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811417302
更新日期:2012-07-01 00:00:00
abstract::Cervical adenopathy as the sole presentation of tuberculosis is seen infrequently in the pediatric age group. Despite modern treatment and public health measures, tuberculous cervical adenitis persists, and its prompt diagnosis and treatment are important from both a clinical and preventive health perspective. The aut...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288902800905
更新日期:1989-09-01 00:00:00
abstract::A common presenting problem of children in pediatric practice is the constellation of symptoms involving difficulty in completing assignments, trouble with written work, and organizational problems. Typically, these children do not have difficulty with reading but show problems with academic achievement. We have recen...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288302200401
更新日期:1983-04-01 00:00:00
abstract::Prior to the 1990s, most 46,XX infants with clitoromegaly secondary to congenital adrenal hyperplasia were treated with feminizing genitoplasty to make their cosmetic appearance congruent with their genotypic sex. A 2006 consensus statement for the management of intersex disorders accepted input from patient advocates...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818803407
更新日期:2018-12-01 00:00:00
abstract::The frequency of accessory nipples in black Americans is almost eight times greater than in white European patients. Association of a wide range of abnormalities with supernumerary nipples in whites has, thus far, not been our experience in black Americans. ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288202100107
更新日期:1982-01-01 00:00:00
abstract::An 8-year-old girl with Hallermann-Streiff syndrome (oculomandibulofacial syndrome) was examined. She had a history of severe snoring, reported nocturnal apnea, excessive daytime hypersomnolence, nocturnal enuresis, and failure to thrive. Overnight polysomnography confirmed severe obstructive sleep apnea. Long-term na...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900212
更新日期:1990-02-01 00:00:00
abstract::Our objective was to determine if C-reactive protein (CRP) and ferritin values alone and in combination are associated with mortality among hospitalized children. All hospitalized patients at our institution with a CRP or ferritin assay in 2015 and 2016 were included. Area under the receiver operating curves (AUROC) w...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819837352
更新日期:2019-06-01 00:00:00
abstract::The Danish social system provides competent, accessible, continuous, and coordinated medical care to the pediatric population. The pediatrician does not deal with the routine aspects of well-infant and child care but is rather hospital based and acts on consultant to the generalists in his district. The generalist has...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287501400409
更新日期:1975-04-01 00:00:00
abstract::The American Academy of Pediatrics California Chapter 3 created a 20-minute training video targeting barriers to strong provider recommendation of the human papillomavirus (HPV) vaccine. The video included clinical vignettes featuring pediatricians modeling counseling techniques with vaccine-hesitant families. Ninety-...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818805217
更新日期:2019-01-01 00:00:00
abstract::Falszewska A, Dziechciarz P, Szajewska H. The diagnostic accuracy of Clinical Dehydration Scale in identifying dehydration in children with acute gastroenteritis: a systematic review. Clin Pediatr (Phila). 2014;53:1181-8. (Original DOI: 10.1177/0009922814538493 ). ...
journal_title:Clinical pediatrics
pub_type: 杂志文章,已发布勘误
doi:10.1177/0009922817711992
更新日期:2018-01-01 00:00:00
abstract::Much attention has been focused on the natural history of gastroesophageal reflux (GER) in neurologically normal infants which generally resolves by two years of age. In contrast, little is known of the outcome of GER diagnosed in normal older children. The charts of 32 children (21 males) without neurologic or esopha...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289103000705
更新日期:1991-07-01 00:00:00
abstract:BACKGROUND:Sexually transmitted infections (STIs) are common among adolescents, and multiple STIs over one's lifetime can increase health risks. Few studies have assessed lifetime STI prevalence. This study evaluates minority, underserved adolescents' self-reported lifetime STI history and objective STI rates. METHODS...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814533816
更新日期:2014-08-01 00:00:00
abstract::The purpose of this study was to assess the relationship between the clinical findings before starting treatment and the development quotient in children treated for congenital hypothyroidism. Patients with congenital hypothyroidism (n = 129) were divided into favorable and unfavorable groups according to intellectual...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806289326
更新日期:2007-01-01 00:00:00
abstract::An acutely ill 4-year-old girl with Rocky Mountain spotted fever (RMSF) was found to have a coagulation inhibitor. This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation inhibitor. Hemostatic abnormaliti...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600905
更新日期:1987-09-01 00:00:00
abstract::We conducted a retrospective study to identify electrocardiogram (ECG) and echocardiogram utilization among patients presenting for a follow-up cardiology evaluation with innocent heart murmur between 2012 and 2014. The 2014 echocardiogram Appropriate Use Criteria was applied. We observed high rates of ordering ECGs a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922818787280
更新日期:2018-10-01 00:00:00
abstract::Follow-up survival and health information were obtained, after a median of 27.5 years, from 132 patients who had been seen originally as children with nephrotic syndrome between 1951 and 1967. Ninety seven patients were alive. Recurring edema or proteinuria, or both, persisted in 15 percent of those still alive. Eight...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288802700201
更新日期:1988-02-01 00:00:00
abstract:OBJECTIVE:To measure the willingness and ability of primary care pediatricians (PCPs) to accept children and youth with special health care needs (CYSHCN) into their practices. METHODS:Surveys were mailed to 1441 members of the Illinois Chapter of the American Academy of Pediatrics practicing primary care. RESULTS:In...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922813476572
更新日期:2013-04-01 00:00:00
abstract::Excessive television (TV) viewing by children can lead to negative health and developmental outcomes. Using structural equation modeling, this study tests a conceptual model to understand social and familial factors associated with TV exposure among a sample of 767 Head Start families with children between the ages of...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817738340
更新日期:2018-07-01 00:00:00
abstract::A masked, randomized, parallel growth study was conducted in infants fed an amino acid-based formula (AF) or an extensively hydrolyzed casein-based formula (HF). Infants were enrolled between 0 and 9 days and studied to 112 days of age. Growth, formula intake, stool patterns, and serum albumin concentrations were asse...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/0009922813492883
更新日期:2013-10-01 00:00:00
abstract::A 6-year-old girl with sickle cell disease was admitted to the hospital with the diagnosis of the acute chest syndrome. The laboratory findings and the radionuclear lung scan supported a diagnosis of pulmonary infarction rather than pneumonia. She improved with intravenous fluids, oxygen, penicillin, and theophylline....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502401209
更新日期:1985-12-01 00:00:00