Abstract:
:Follow-up survival and health information were obtained, after a median of 27.5 years, from 132 patients who had been seen originally as children with nephrotic syndrome between 1951 and 1967. Ninety seven patients were alive. Recurring edema or proteinuria, or both, persisted in 15 percent of those still alive. Eight of 11 parous women reported relapses during pregnancy. There was no apparent increase in malignancies, atopic diseases, clinical defects in cell-mediated immunity, or cardiovascular diseases. Twenty two patients (17%) died of renal causes between 3 months and 8 years after the onset of nephrotic syndrome. Steroid resistance was the presenting feature universally predictive of a poor outcome; nine of the 11 such patients died and the other two are now receiving hemodialysis. Hematuria was present initially in 41 percent of the patients who died of renal causes, compared with 14 percent of those still alive. Hypertension was noted on the first examination in 22 percent of those who died of renal causes, compared with 10 percent of those alive.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Wynn SR,Stickler GB,Burke ECdoi
10.1177/000992288802700201subject
Has Abstractpub_date
1988-02-01 00:00:00pages
63-8issue
2eissn
0009-9228issn
1938-2707journal_volume
27pub_type
杂志文章abstract::Two children presented with autoimmune alternating hypo- and hyperthyroidism related to the presence of blocking and stimulating thyroid antibodies. It was difficult to control their thyroid function adequately with an appropriate single drug regimen, and both children underwent total thyroidectomy with subsequent sta...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922811412583
更新日期:2011-11-01 00:00:00
abstract::The duration of hospitalization for newborns has declined dramatically, driven by efforts to control health-care costs as well as by efforts to demedicalize childbirth. In order to determine the clinical basis for this practice, the quality of the published literature on discharge timing was analyzed. Thirteen experim...
journal_title:Clinical pediatrics
pub_type: 杂志文章,meta分析
doi:10.1177/000992289503401201
更新日期:1995-12-01 00:00:00
abstract::Topical application of ocular drugs may cause serious adverse ocular or systemic side effects. Children are at greater risk for systemic side effects because ocular dosing is not weight-adjusted, and infants are especially vulnerable as a consequence of the inability to efficiently metabolize the drug, and/or an immat...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280404300114
更新日期:2004-01-01 00:00:00
abstract::Patient-centered medical home (PCMH) transformation has been challenging for pediatric practices, in part because of the National Committee for Quality Assurance (NCQA) PCMH focus on conditions and processes specific to adult patients. Realizing the potential challenges faced by pediatric practices, Vermont supported ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816669788
更新日期:2017-06-01 00:00:00
abstract::Knowledge of the characteristics of family structure may be helpful to the pediatrician for predicting child abuse. During the past several decades progressive shifts from the classic family unit of two biological parents and their children to a variety of parental living arrangements have occurred. Most notable are t...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992280604500201
更新日期:2006-03-01 00:00:00
abstract::Helicobacter pylori (H. pylori) is responsible for one of the most frequently encountered infectious diseases worldwide. H. pylori infection can lead to the development of gastritis and peptic ulcer disease. The presence of H. pylori in the human stomach also represents an increased risk for gastric cancer and gastric...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
doi:10.1177/000992289603500401
更新日期:1996-04-01 00:00:00
abstract::Two patients with acute osteomyelitis had technetium 99m methylene diphosphonate bone images that were misinterpreted. A review of six prospective evaluations of technetium scanning in the diagnosis of acute osteomyelitis shows that bone image interpretation may be misleading in five to seven per cent of pediatric pat...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001900904
更新日期:1980-09-01 00:00:00
abstract::A masked, randomized, parallel growth study was conducted in infants fed an amino acid-based formula (AF) or an extensively hydrolyzed casein-based formula (HF). Infants were enrolled between 0 and 9 days and studied to 112 days of age. Growth, formula intake, stool patterns, and serum albumin concentrations were asse...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/0009922813492883
更新日期:2013-10-01 00:00:00
abstract::A required PL-3 rotation in community pediatrics, including assignments to preschool and school settings, private pediatric offices, and in-hospital responsibilities, is described. A university-affiliated community hospital provides the organizational base for the program. After 14 PL-3 rotations, analysis of program ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288102000403
更新日期:1981-04-01 00:00:00
abstract::The purpose of this study was to examine the immunization beliefs and practices of physicians in our community. A two-page descriptive survey of immunization practices and knowledge of vaccine contraindications was sent to all community physicians on the staff of Children's Hospital Medical Center in Cincinnati, Ohio....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289603500205
更新日期:1996-02-01 00:00:00
abstract::In a review of 17 adolescents and children (excluding newborns) with definite clinical signs, symptoms, and laboratory findings of hypothyroidism, 11 patients (65%) had anemia. The mean corpuscular volume (MCV) of the red blood cells was either macrocytic or normocytic. The hemoglobin did not correlate with the serum ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288102001102
更新日期:1981-11-01 00:00:00
abstract::This study assessed the impact of respiratory syncytial virus-confirmed hospitalizations (RSVH) on caregivers of high-risk preterm infants. Caregivers for infants born at 29 to 35 weeks' gestational age and hospitalized for confirmed RSV disease responded to measures of self-rated and perceived infant stress (1-7; 7 =...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922819843639
更新日期:2019-07-01 00:00:00
abstract::Five cases of bacterial epididymo-orchitis are presented. These patients demonstrate three distinct mechanisms of bacterial infection of the intrascrotal structures: epididymo-orchitis as a presentation and a complication of urinary tract infection; epididymo-orchitis associated with sexually transmitted disease; and ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001901206
更新日期:1980-12-01 00:00:00
abstract::The value of sonography in assessing chronic abdominal pain (CAP) in children, the characteristics of CAP, and the local pediatrician's practice in evaluating CAP are reported. Fifty-seven patients with CAP had abdominal and/or pelvic sonography; 56 were normal. One sonogram showed an ovarian cyst on the side opposite...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289303200304
更新日期:1993-03-01 00:00:00
abstract:BACKGROUND:Waist circumference (WC) to height ratio (WC/HT) is used as a measure of central obesity. However, the optimum ratio that will separate populations with high from low cardiovascular risk remains controversial. This investigation evaluates an optimum WC/HT value to define central obesity in children. METHODS...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922814557784
更新日期:2015-06-01 00:00:00
abstract::The use of totally implantable central venous catheters with reservoirs has grown steadily over the past few years. These systems mitigate many of the inherent problems associated with catheter systems that protrude from the skin. Totally implantable systems are easily cared for and permit activities such as swimming....
journal_title:Clinical pediatrics
pub_type: 信件
doi:10.1177/000992289303200515
更新日期:1993-05-01 00:00:00
abstract::The purpose of this study was to analyze the effects of breast-feeding on cognitive and motor development. A prospective cohort study was carried out enrolling 249 babies from 2 rural and urban areas. Cognitive development was assessed at the age of 18 months. Results show that adjusted scores on the mental developmen...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280304200106
更新日期:2003-01-01 00:00:00
abstract::Of 1045 children admitted with gastroenteritis over a 12-month period and studied retrospectively, serum sodium level was tested in 802. Sixty patients (7.5%) had hypernatremic dehydration (HD). The peak incidence of HD, the highest serum sodium levels, and the worst outcome were all encountered in infants under the a...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300501
更新日期:1984-05-01 00:00:00
abstract::Nephrotic syndrome (NS) is one of the most common causes of chronic kidney disease in children. Mostly, NS is controlled by steroids. In spite of this, 10% to 20% of the patients have steroid resistant NS (SRNS), and the rest have steroid sensitive NS (SSNS). Eighty-seven children with NS (66 SSNS; 21SRNS) were retros...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922816645521
更新日期:2017-02-01 00:00:00
abstract::Background. Testicular torsion is a common surgical emergency in children that requires a high index of suspicion, early diagnosis, and exploration. Most children present early to their primary pediatricians or physicians. The aim of this retrospective study is to determine the surgical outcome of testicular torsion w...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820903037
更新日期:2020-05-01 00:00:00
abstract::We assessed the relationship between breastfeeding and antimicrobial use in the first year of life in healthy infants by surveying a military population of healthy term infants with questionnaires obtained at the 6-month and 12-month well-baby visits. Breastfed (BF) babies spent 48% as much time receiving antimicrobia...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280404300708
更新日期:2004-09-01 00:00:00
abstract::Families of 49 hearing-impaired children responded to a questionnaire requesting information about the identification of their child's hearing loss. Parents were the first to suspect the hearing loss in 48 cases but more often than not were told that the child would outgrow it or was too young to test. When profession...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289103000202
更新日期:1991-02-01 00:00:00
abstract::Emergency physicians need to clinically differentiate children with and without radiographic evidence of pneumonia. In this prospective cohort study of 510 patients 2 to 59 months of age presenting with symptoms of lower respiratory tract infection, 100% were evaluated with chest radiography and 44 (8.6%) had pneumoni...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400508
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:The purpose of our study was to compare caregiver perceptions of fever between ethnicities in a population with a large percentage of Hispanics. METHODS:A 20-item, cross-sectional survey was collected from English- and Spanish-speaking parents of children. Questions addressed level of parental worry, parent...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809336208
更新日期:2010-02-01 00:00:00
abstract::This study surveyed pediatric primary care providers at a major academic center regarding their attitudes and practices of obesity screening, prevention, and treatment. The authors compared the care providers' reported practices to the 2007 American Medical Association and Centers for Disease Control and Prevention Ex...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922810394833
更新日期:2011-05-01 00:00:00
abstract::With many asthmatic children for whom emotional factors are significant, joint pediatric and psychiatric management is essential. A three-level model of collaboration is presented, including (1) pediatric care, (2) psychiatric consultation, and (3) inpatient psychosomatic treatment. The organization, professional role...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288102001203
更新日期:1981-12-01 00:00:00
abstract:OBJECTIVE:To assess weight stigma, self-perception of weight status, and factors contributing to accurate self-perception of weight status in obese youth presenting for treatment at a hospital-based multidisciplinary weight management program. METHODS:Participants (N = 97; mean age = 8.56 +/- 1.66 years) used a figura...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809346571
更新日期:2010-04-01 00:00:00
abstract::Two hundred and seventy one infants were enrolled in a study to compare six different methods of treating the umbilical cord. Antimicrobial control was equal for all methods. Repeated triple dye application was considered least acceptable by staff and parents and had the longest attachment time. Povidone-iodine was as...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992288802700302
更新日期:1988-03-01 00:00:00
abstract::The successful eradication of poliomyelitis in the United States has primarily been due to the use of oral poliovirus vaccine (OPV). However, because of the risk of vaccine-associated paralytic poliomyelitis with OPV, the use of inactivated poliovirus vaccine (IPV) has become the accepted option. We performed a cross-...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280104000802
更新日期:2001-08-01 00:00:00
abstract::To compare parental compliance with after-hours triage advice provided by telephone advice nurses and on-call pediatricians, a randomized controlled trial was undertaken at a university general pediatrics practice that enrolled parents or guardians calling for after-hours advice. Advice calls were randomized to a call...
journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992280304200707
更新日期:2003-09-01 00:00:00