Autoimmune alternating hypo- and hyperthyroidism in children.

Abstract:

:Two children presented with autoimmune alternating hypo- and hyperthyroidism related to the presence of blocking and stimulating thyroid antibodies. It was difficult to control their thyroid function adequately with an appropriate single drug regimen, and both children underwent total thyroidectomy with subsequent stable management with levothyroxine replacement therapy postsurgically. Although this phenomenon is well described in adults, this report is the first of such occurrence in children. The possible mechanism for the variation in the type of clinical presentation and options for management are discussed.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Mathew RP,Moore DJ

doi

10.1177/0009922811412583

subject

Has Abstract

pub_date

2011-11-01 00:00:00

pages

1040-4

issue

11

eissn

0009-9228

issn

1938-2707

pii

0009922811412583

journal_volume

50

pub_type

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