Abstract:
BACKGROUND:Benefits associated with probiotic administration to children seeking emergency department care with diarrheal disease are unknown. METHODS:In this 3-site, double-blind, placebo-controlled study, children aged 4 to 48 months with gastroenteritis were randomized to receive 5 days of placebo, low-dose (4 × 10(9) colony forming units per day), or high-dose (8 × 10(9) colony forming units per day) probiotic (Lactobacillus helveticus and Lactobacillus rhamnosus) in a 2:1:1 ratio. The primary outcome was day care absenteeism. RESULTS:The proportion of children missing a day of day care was 63% (39/62) and 61% (37/61) in the placebo and probiotic arms, respectively (95%CI -14.6% to 18.9%). The proportions experiencing unscheduled health care provider visits and intravenous fluid rehydration were 24% (15/62), 7% (4/62), and 30% (18/61), 5% (3/61) in the placebo and probiotic study arms, respectively (P = .52 and P = .65). None of the results differed based on probiotic dose. CONCLUSIONS:The probiotic evaluated did not reduce absenteeism. Since power was suboptimal, further evaluation is required.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Freedman SB,Sherman PM,Willan A,Johnson D,Gouin S,Schuh S,Pediatric Emergency Research Canada (PERC).doi
10.1177/0009922815569200subject
Has Abstractpub_date
2015-10-01 00:00:00pages
1158-66issue
12eissn
0009-9228issn
1938-2707pii
0009922815569200journal_volume
54pub_type
杂志文章,多中心研究,随机对照试验abstract::Over-the-counter cold remedies are widely used for symptomatic relief of upper respiratory tract infections. The safety of these drugs is not well established in infants and their efficacy is questionable. Our aim was to study the attitude of family physicians and pediatricians toward the use of cold remedies in infan...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806295281
更新日期:2006-11-01 00:00:00
abstract::A 6-year-old girl with sickle cell disease was admitted to the hospital with the diagnosis of the acute chest syndrome. The laboratory findings and the radionuclear lung scan supported a diagnosis of pulmonary infarction rather than pneumonia. She improved with intravenous fluids, oxygen, penicillin, and theophylline....
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502401209
更新日期:1985-12-01 00:00:00
abstract::Tests with the Bayley Motor Scale were given to 288 infants, equally divided by sex, in Yucatan, Mexico. These were 2 to 54 weeks in age and came from three sociocultural levels. In comparison to USA infants, early acceleration of motor development was followed by a marked downward trend. This phenomenon, if observed ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287801701106
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journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::A considerable percentage of American children and adults fail to learn adequate literacy skills and read below a third grade level. Shared book reading is perhaps the single most important activity to prepare young children for success in reading. The primary objective of this manuscript was to critically review the ...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
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abstract::Scleredema is a rare connective disease which must be differentiated from scleroderma in childhood. Scleredema is characterized by thickening of the dermis of the neck, head, and upper trunk. We report a case of scleredema in an 8-year-old boy with coincident streptococcal colonization. The patient report demonstrates...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
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abstract::The goal of this study was to describe a single emergency physician's experience with symptomatic blunt head injury in children and prospectively assess the sensitivity and predictive value of the neurologic examination. The author utilized a prospective patient series comparing neurologic examination with computed to...
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abstract::Neisseria meningitidis is an important cause of fulminant septicemia and meningitis in children. Only limited reports of mild disease associated with this organism exist. In this study, we describe eight children, ages 2.5-19 months, with mild meningococcal disease and characterize the meningococcal isolates from some...
journal_title:Clinical pediatrics
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abstract::The Vaccines for Children (VFC) program distributes one half of all vaccines administered to US children. Compared with commercial vaccine distribution, VFC distribution is more complex. This prospective observational study compares the delivery and administration of VFC versus non-VFC influenza vaccine in US pediatri...
journal_title:Clinical pediatrics
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doi:10.1177/0009922812470868
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abstract::Transient synovitis of the hip is a common cause of hip pain in children. The etiology of transient synovitis of the hip is unknown. Lyme arthritis is characterized by brief, often recurrent episodes of oligoarthritis. Lyme arthritis most often affects a single knee, but hip involvement is uncommon. This report descri...
journal_title:Clinical pediatrics
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abstract::Acute splenic sequestration crisis ( ASSC ), a common complication in homozygous sickle cell anemia, has been described infrequently in sickle-hemoglobin C (SC) disease in the absence of high altitude exposure. In this report, we describe three children with hemoglobin SC disease who developed episodes of ASSC that we...
journal_title:Clinical pediatrics
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doi:10.1177/000992288402300612
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abstract::Between 1979 and 1981, 22 children with osteomyelitis and/or septic arthritis were hospitalized at Soroka University Hospital. Streptococcus pneumoniae was cultured in five of the children, four of whom were under 2 years of age. In four other children under 2 years of age, Haemophilus influenzae was cultured. Staphyl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288502400305
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abstract::The case of a six-year-old boy with newly diagnosed tracheoesophageal fistula of the H-type is presented. This diagnosis is usually made in the neonatal period, but since the symptoms may mimic other respiratory illnesses and radiologic diagnosis may be difficult, the condition may go undiagnosed for years. Since corr...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289002900210
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abstract::Two children with congenital ocular motor apraxia (C-OMA) associated with congenital malformations of the central nervous system (CNS) are presented, and the literature is reviewed. C-OMA is an abnormality of ocular motility characterized by defective or absent voluntary horizontal gaze, associated with a characterist...
journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
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abstract::Eighty children with acute otitis media (AOM) were prospectively studied to determine the correlation and clinical usefulness of nasopharyngeal (NP), conjunctival (CONJ), and middle ear fluid (MEF) cultures. NP cultures correlated more accurately with MEF (p less than 0.01) than did CONJ cultures (p less than 0.05) fo...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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abstract::The Adult Congenital and Pediatric Cardiology (ACPC) Section of the American College of Cardiology sought to develop quality indicators/metrics for ambulatory pediatric cardiology practice. The objective of this study was to report the creation of metrics for patients with Kawasaki disease. Over a period of 5 months, ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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journal_title:Clinical pediatrics
pub_type: 杂志文章
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更新日期:1998-02-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289603500205
更新日期:1996-02-01 00:00:00
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journal_title:Clinical pediatrics
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更新日期:2007-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
abstract::The objective of the study was to examine differences in pediatric resident perceptions and practices related to child mental health conditions in continuity clinic settings with versus without on-site mental health professionals (MHPs). A 20-item questionnaire, based on the American Academy of Pediatrics Periodic Sur...
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更新日期:2017-11-01 00:00:00
abstract::This report describes a 1-month-old female with bacteremia and meningitis complicated by an infected cephalohematoma that resulted from hematogenous seeding. This report serves as a reminder that, although occurring rarely, inflammation overlying a cephalohematoma in an infant with bacteremia can indicate focal infect...
journal_title:Clinical pediatrics
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更新日期:2009-09-01 00:00:00
abstract::More than 300 patients who presented consecutively to a sexual abuse clinic, a family planning clinic, and a family practice clinic filled out an anonymous survey regarding unwanted sexual experiences. In the family planning and family practice clinics, 40% of females and 16% of males reported having at least one unwa...
journal_title:Clinical pediatrics
pub_type: 杂志文章,多中心研究
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更新日期:1995-06-01 00:00:00
abstract::The urinary tract is a common site of infection in the hospitalized, institutionalized, or ambulatory patient population. Ideally, urine should be cultured immediately or refrigerated up to 24 hours for quantitative examination for microorganisms. In the evaluation of patients at their homes or in long-term care facil...
journal_title:Clinical pediatrics
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abstract:AIMS:The aims of this study were to detect the infection rates of DNA viruses in liver tissue of biliary atresia and to investigate the effect of perinatal infection of cytomegalovirus in biliary atresia. METHODS:A total of 85 liver biopsies (taken during Kasai portoenterostomy) were tested by fluorescence quantitativ...
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更新日期:2012-02-01 00:00:00
abstract::This study aims to evaluate the cost-benefit of vaccination services, mostly partial series administration, provided by a mobile clinic program (MCP) in Houston for children of transient and low-income families. The study included 469 patients who visited the mobile clinics on regular service days in 2 study periods i...
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更新日期:2020-06-01 00:00:00