Assessing the effect of docosahexaenoic acid on cognitive functions in healthy, preschool children: a randomized, placebo-controlled, double-blind study.

Abstract:

:The utility of multicenter cognitive test methodology and resultant outcomes of supplementation with docosahexaenoic acid in healthy 4-year-old children was evaluated in a randomized, placebo-controlled, double-blind study. Subjects received 400-mg/d docosahexaenoic acid (n = 85) or matching placebo (n = 90) in capsules for 4 months. Cognitive tests included the Leiter-R Test of Sustained Attention, Peabody Picture Vocabulary Test, Day-Night Stroop Test, and Conners' Kiddie Continuous Performance Test. The relationship of docosahexaenoic acid levels in capillary whole blood from a subsample (n = 93) with scores on cognitive tests was evaluated. For each test, results indicated that changes from baseline to end of treatment were not statistically significantly different between the docosahexaenoic acid group and the placebo group. Regression analysis, however, yielded a statistically significant positive (P = .018) association between the blood level of docosahexaenoic acid and higher scores on the Peabody Picture Vocabulary Test, a test of listening comprehension and vocabulary acquisition.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Ryan AS,Nelson EB

doi

10.1177/0009922807311730

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

355-62

issue

4

eissn

0009-9228

issn

1938-2707

pii

0009922807311730

journal_volume

47

pub_type

杂志文章,多中心研究,随机对照试验
  • Embracing international children's rights: from principles to practice.

    abstract::As clinicians, pediatricians need to be cognizant of the how the principles of equity, social justice, and children's rights help to inform and guide us as we strive for the health and well being of all children. Children of the world are frequently the most vulnerable global citizens facing poverty, displacement, and...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922811417302

    authors: Oberg CN

    更新日期:2012-07-01 00:00:00

  • Role of routine urinalysis in asymptomatic pediatric patients.

    abstract::This study was done to evaluate the spectrum of diagnoses and identify risk factors for significant kidney disease in asymptomatic children with proteinuria and/or microhematuria detected by routine urinalysis. Clinical and laboratory data were obtained by retrospective chart review of 239 patients referred to a terti...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992280504400105

    authors: Chandar J,Gómez-Marín O,del Pozo R,Sanders L,Montane B,Abitbol C,Strauss J,Zilleruelo G

    更新日期:2005-01-01 00:00:00

  • Mothers' perceptions of family health history and an online, parent-generated family health history tool.

    abstract::Family health history (FHH) can identify families at increased risk for disease. Purpose. To learn mothers' (1) perceptions of the benefits of FHH and (2) willingness to complete a FHH tool, My Family Health Portrait (MFHP). Methods. Qualitative in-depth interviews were conducted with mothers recruited through Cincinn...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922812467531

    authors: Berger KA,Lynch J,Prows CA,Siegel RM,Myers MF

    更新日期:2013-01-01 00:00:00

  • Utilization of Antipyretics for Nonurgent Fever in a Pediatric Emergency Department.

    abstract::This retrospective cohort study aimed to describe antipyretic use among healthy patients in a pediatric emergency department (ED) with nonurgent fever defined as: triage level 4 or 5, chief complaint fever or temperature 38°C to 39°C, and otherwise normal vital signs, and determine if antipyretic administration is ass...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922817734356

    authors: Nelson CE,Ostapenko S,Zorc JJ,Balamuth F

    更新日期:2018-06-01 00:00:00

  • The long term benefits of a comprehensive teenage pregnancy program.

    abstract::A comprehensive program was founded in 1982 to provide adolescents with prenatal and family planning care. The program's impact through its first five years of operation on medical aspects of pregnancy course and fetal outcome will be the subject of a separate report. This study examines subsequent maternal and infant...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992289103000508

    authors: Rabin JM,Seltzer V,Pollack S

    更新日期:1991-05-01 00:00:00

  • Review of medical reports on pedophilia.

    abstract::The present report is a review of all 554 papers published on Medline on pedophilia. The first discussion is the history of the disorder from ancient Greece to the present time, especially the influence of the liberal country of the Netherlands, the North American Man-Boy Love Association, and the sexual crisis in the...

    journal_title:Clinical pediatrics

    pub_type: 历史文章,杂志文章,评审

    doi:10.1177/0009922807301483

    authors: Hughes JR

    更新日期:2007-10-01 00:00:00

  • Pediatric-Informed Facilitation of Patient-Centered Medical Home Transformation.

    abstract::Patient-centered medical home (PCMH) transformation has been challenging for pediatric practices, in part because of the National Committee for Quality Assurance (NCQA) PCMH focus on conditions and processes specific to adult patients. Realizing the potential challenges faced by pediatric practices, Vermont supported ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922816669788

    authors: Harder VS,Long WE,Varni SE,Samuelson J,Shaw JS

    更新日期:2017-06-01 00:00:00

  • Pneumococcal osteomyelitis. An unusual cluster of cases.

    abstract::Between 1979 and 1981, 22 children with osteomyelitis and/or septic arthritis were hospitalized at Soroka University Hospital. Streptococcus pneumoniae was cultured in five of the children, four of whom were under 2 years of age. In four other children under 2 years of age, Haemophilus influenzae was cultured. Staphyl...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288502400305

    authors: Hadari I,Dagan R,Gedalia A,Jeanine N,Moses S

    更新日期:1985-03-01 00:00:00

  • Primary care physicians' knowledge of and confidence in their referrals for special education services in 3- to 5-year-old children.

    abstract:BACKGROUND:Children 3 to 5 years old with developmental delays are eligible for special education services. OBJECTIVE:To assess primary care physicians' (PCPs) knowledge, attitudes, and practices regarding their referrals to the special education system on behalf of children 3 to 5 years old. DESIGN/METHODS:Mail surv...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922813503036

    authors: Hastings EA,Lumeng JC,Clark SJ

    更新日期:2014-02-01 00:00:00

  • Bullying on Television: 1960-2010.

    abstract::Bullying is a serious issue for adolescents, with health consequences both at the time of victimization and later on in adulthood. Aggression in the media is an area that has been explored as a contributing factor to bullying behavior. This study aims to determine if the incidence of aggression in popular television s...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922815614353

    authors: Petranovich KA,Bapty SJ,Maestas TS,Strasburger VC

    更新日期:2016-10-01 00:00:00

  • Clinical quality improvement for identification and management of overweight in pediatric primary care practices.

    abstract::The purpose of the Pediatric Overweight Quality Improvement Initiative (POWQII) was to demonstrate the feasibility and value of simple interventions for improving pediatric care and to address the additional needs of overweight and obese children. Practices were recruited from around New Mexico, with 16 pediatricians ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922813480844

    authors: Brandt KL,Booker JM,McGrath J

    更新日期:2013-07-01 00:00:00

  • Vertebral fractures in boys with Duchenne muscular dystrophy.

    abstract::Osteoporosis causes significant morbidity for boys with Duchenne muscular dystrophy. Corticosteroid therapy given to prolong mobility may increase the rate of osteoporosis and risk of fracture. This study of 33 boys with Duchenne muscular dystrophy determined retrospectively the incidence of vertebral fractures partic...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992280304200408

    authors: Bothwell JE,Gordon KE,Dooley JM,MacSween J,Cummings EA,Salisbury S

    更新日期:2003-05-01 00:00:00

  • A prospective study of rotavirus diarrhea in children under 1 year of age.

    abstract::The aim of this study was to document the changing clinical profile and prognosis of acute diarrhea in infants. This was a prospective observational study with follow-up. Demographic, anthropometric, and clinical data were collected in children younger than 1 year with acute diarrhea. Stool was examined under the micr...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922807300700

    authors: Misra S,Sabui TK,Basu S,Pal N

    更新日期:2007-10-01 00:00:00

  • Underutilization of Preventive Asthma Visits Among Urban Children With Persistent Asthma.

    abstract::National guidelines recommend that children with persistent asthma have at least 2 preventive asthma visits (PAVs) per year. We sought to determine the percent of urban children with persistent asthma who had a PAV in the past year, and to identify differences in demographics, health-related variables, and management ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922816685816

    authors: Gundewar A,David R,Frey SM,Fagnano M,Halterman JS

    更新日期:2017-12-01 00:00:00

  • Impact of a Personalized Audit and Feedback Intervention on Antibiotic Prescribing Practices for Outpatient Pediatric Community-Acquired Pneumonia.

    abstract::Antibiotic choice for pediatric community-acquired pneumonia (CAP) varies widely. We aimed to determine the impact of a 6-month personalized audit and feedback program on primary care providers' antibiotic prescribing practices for CAP. Participants in the intervention group received monthly personalized feedback. We ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922820928054

    authors: Diaz MCG,Handy LK,Crutchfield JH Jr,Cadilla A,Hossain J,Werk LN

    更新日期:2020-10-01 00:00:00

  • An Integrative Review of Family Health History in Pediatrics.

    abstract::The aim of this integrative review is to investigate current literature regarding family health history (FHH) taking practices, attitudes, and challenges in the pediatric outpatient setting. FHH is a known clinical tool for providers; however, there are no explicit standards for pediatric FHH collection. The integrati...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922820943474

    authors: Kwong L,Bodurtha J,Busch DW

    更新日期:2020-12-01 00:00:00

  • Clinical features of mild systemic meningococcal disease with characterization of bacterial isolates.

    abstract::Neisseria meningitidis is an important cause of fulminant septicemia and meningitis in children. Only limited reports of mild disease associated with this organism exist. In this study, we describe eight children, ages 2.5-19 months, with mild meningococcal disease and characterize the meningococcal isolates from some...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288502401101

    authors: Edwards KM,Jones LM,Stephens DS

    更新日期:1985-11-01 00:00:00

  • Child Life Reduces Distress and Pain and Improves Family Satisfaction in the Pediatric Emergency Department.

    abstract::This study evaluated the effects of Certified Child Life Specialist (CCLS) intervention on pediatric distress and pain and family satisfaction during routine peripheral intravenous (PIV) line placement in the emergency department (ED). A convenience sample of 78 children (3-13 years) requiring PIV placement for their ...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922818798386

    authors: Sanchez Cristal N,Staab J,Chatham R,Ryan S,Mcnair B,Grubenhoff JA

    更新日期:2018-11-01 00:00:00

  • Helicobacter pylori disease in childhood.

    abstract::Helicobacter pylori (H. pylori) is responsible for one of the most frequently encountered infectious diseases worldwide. H. pylori infection can lead to the development of gastritis and peptic ulcer disease. The presence of H. pylori in the human stomach also represents an increased risk for gastric cancer and gastric...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,评审

    doi:10.1177/000992289603500401

    authors: Blecker U

    更新日期:1996-04-01 00:00:00

  • What are providers' reporting requirements for children who witness domestic violence?

    abstract::Each year, 3.3 to 10 million children are exposed to domestic violence/abuse (DV). Providers' reporting obligations for these children are unclear. The child maltreatment statutes available on state's web sites (through August 2003) were reviewed. Only Alaska defines DV in the presence of a child as child abuse within...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章,评审

    doi:10.1177/000992280404300506

    authors: Zink T,Kamine D,Musk L,Sill M,Field V,Putnam F

    更新日期:2004-06-01 00:00:00

  • Testicular Loss in Children Due to Incorrect Early Diagnosis of Torsion.

    abstract::Background. Testicular torsion is a common surgical emergency in children that requires a high index of suspicion, early diagnosis, and exploration. Most children present early to their primary pediatricians or physicians. The aim of this retrospective study is to determine the surgical outcome of testicular torsion w...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922820903037

    authors: Kumar V,Matai P,Prabhu SP,Sundeep PT

    更新日期:2020-05-01 00:00:00

  • Pediatrician-parent communication in a continuity-of-care setting.

    abstract::This study investigated pediatrician-parent communication by content, analyzing medical encounters in a setting providing continuity of care. Thirty-eight encounters between middle class families and three senior pediatricians were audio-taped, transcribed, and analyzed for content. The categories of medical communica...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288202100507

    authors: Arntson PH,Philipsborn HF

    更新日期:1982-05-01 00:00:00

  • A urine preservative system to maintain bacterial counts. A laboratory and clinical evaluation.

    abstract::The urinary tract is a common site of infection in the hospitalized, institutionalized, or ambulatory patient population. Ideally, urine should be cultured immediately or refrigerated up to 24 hours for quantitative examination for microorganisms. In the evaluation of patients at their homes or in long-term care facil...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288502400704

    authors: Goodman LJ,Kaplan RL,Landau W,Jung E,Barrett JE,Levin S,Harris AA

    更新日期:1985-07-01 00:00:00

  • Parental compliance with after hours telephone triage advice: nurse advice service versus on-call pediatricians.

    abstract::To compare parental compliance with after-hours triage advice provided by telephone advice nurses and on-call pediatricians, a randomized controlled trial was undertaken at a university general pediatrics practice that enrolled parents or guardians calling for after-hours advice. Advice calls were randomized to a call...

    journal_title:Clinical pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1177/000992280304200707

    authors: Lee TJ,Baraff LJ,Wall SP,Guzy J,Johnson D,Woo H

    更新日期:2003-09-01 00:00:00

  • Physician and patient characteristics associated with discussion of psychosocial health during pediatric primary care visits.

    abstract::This study examined whether physical pain, mental health symptoms, and provider characteristics were associated with the discussion of children's behavior, mood, getting along with others, school performance, family stress, and parent stress during 800 pediatric primary care visits to 54 providers in 13 clinics. The d...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922807304144

    authors: Brown JD,Wissow LS,Riley AW

    更新日期:2007-11-01 00:00:00

  • Mild splenic sequestration crises in sickle-hemoglobin C disease.

    abstract::Acute splenic sequestration crisis ( ASSC ), a common complication in homozygous sickle cell anemia, has been described infrequently in sickle-hemoglobin C (SC) disease in the absence of high altitude exposure. In this report, we describe three children with hemoglobin SC disease who developed episodes of ASSC that we...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288402300612

    authors: Andrews J,Buchanan GR

    更新日期:1984-06-01 00:00:00

  • Deliberate practice improves pediatric residents' skills and team behaviors during simulated neonatal resuscitation.

    abstract:OBJECTIVE:To evaluate the skills and team behavior of pediatric residents during resuscitation with a high-fidelity mannequin before and after a deliberate practice intervention. METHODS:Each month residents participate in two 90-minute videorecorded sessions (2-3 weeks apart) in an "off-site" delivery room during the...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922813488646

    authors: Cordero L,Hart BJ,Hardin R,Mahan JD,Nankervis CA

    更新日期:2013-08-01 00:00:00

  • A retrospective evaluation of psychosocial impact of long-term growth hormone therapy.

    abstract::Fifty-eight growth hormone (hGH) deficient adults who had received long-term hGH therapy and their families were contacted to assess their past and current status regarding peer relationships, educational and vocational achievements, and self-concepts. Both heterosexual and same-sex peer relationships were reported as...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288602500103

    authors: Mitchell CM,Joyce S,Johanson AJ,Libber S,Plotnick L,Migeon CJ,Blizzard RM

    更新日期:1986-01-01 00:00:00

  • Attendance at Well-Child Visits After Reach Out and Read.

    abstract::Attendance at well-child visits (WCVs) is a sine qua non of preventive care. We hypothesized that Reach Out and Read (ROR) would be associated with better WCV attendance. Parents of children 76 to 72 months at 8 clinics who did not yet have ROR reported how many WCVs their child had attended in the previous year; sepa...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/0009922818822975

    authors: Needlman RD,Dreyer BP,Klass P,Mendelsohn AL

    更新日期:2019-01-07 00:00:00

  • Transcultural understanding of a hereditary disorder. Mucopolysaccharidosis VI in a Vietnamese family.

    abstract::A case study of a family referred for clarification of cultural issues illustrates how a transcultural psychiatric service developed in the pediatric hospital setting can be used to advantage. A Vietnamese family with an inherited disorder. Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome, MPS VI), resisted gene...

    journal_title:Clinical pediatrics

    pub_type: 杂志文章

    doi:10.1177/000992288902801009

    authors: Handelman L,Menahem S,Eisenbruch IM

    更新日期:1989-10-01 00:00:00