Vertebral fractures in boys with Duchenne muscular dystrophy.

Abstract:

:Osteoporosis causes significant morbidity for boys with Duchenne muscular dystrophy. Corticosteroid therapy given to prolong mobility may increase the rate of osteoporosis and risk of fracture. This study of 33 boys with Duchenne muscular dystrophy determined retrospectively the incidence of vertebral fractures particularly after initiation of corticosteroids. A latency period of 40 months after commencement of steroids occurred before the first vertebral fracture appeared. However, by 100 months of treatment approximately 75% had sustained a vertebral fracture.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Bothwell JE,Gordon KE,Dooley JM,MacSween J,Cummings EA,Salisbury S

doi

10.1177/000992280304200408

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

353-6

issue

4

eissn

0009-9228

issn

1938-2707

journal_volume

42

pub_type

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