Presentation of pediatric celiac disease in the United States: prominent effect of breastfeeding.

Abstract:

:Childhood celiac disease (CD) is considered rare in the United States. Consequently there are few data concerning its clinical presentation. A validated questionnaire was distributed to families of children with CD. One hundred forty-one children with biopsy-proven CD were included in the study. We found significant differences in the clinical spectrum of children based on their infant feeding history. Exclusively breastfed children were significantly less likely to report failure to thrive (69% vs 88%, p<0.05) and short stature (37% vs 62%, p<0.05), and had a higher rate of "atypical'' symptoms (p<0.01). Breastfeeding alters the presentation and contributes to atypical presentations of CD and diagnostic delay. Pediatricians need to be aware of the diverse manifestations of celiac disease to reduce diagnostic delay.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

D'Amico MA,Holmes J,Stavropoulos SN,Frederick M,Levy J,DeFelice AR,Kazlow PG,Green PH

doi

10.1177/000992280504400309

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

249-58

issue

3

eissn

0009-9228

issn

1938-2707

journal_volume

44

pub_type

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