Abstract:
:Bedwetting is the most common urologic complaint among children. Wetting frequency at age 7 years varies from 5% to 15%. Treatment has been multimodal: drugs to depress bladder activity, increase urethral resistance, or modulate sleep; electrophysiologic treatment; and, recently, urine production modulation. All of these approaches reflect a lack of sufficient knowledge of the underlying pathophysiology of nocturnal enuresis. Over the last 13 years, enuresis studies at the Institute of Experimental Clinical Research, the University of Aarhus, Denmark, have focused on sleep disturbances, bladder reservoir function, urine output, and a combination of the three. Sleep studies indicate that: enuretic patients are normal sleepers; the voiding characteristics of an enuretic episode are similar to those of voluntary voiding during the day; and enuresis can take place during any stage of sleep, but generally occurs when the bladder is filled to the equivalent of maximal daytime functional capacity. Bladder reservoir capacity appears to be normal and bladder instability an unimportant factor in the pathology of nocturnal enuresis. However, enuretic patients have been shown to lack the normal nocturnal increase in antidiuretic hormone levels and had nocturnal urine production up to four times the volume of functional bladder capacity, which explains the need for bladder emptying. These findings open new avenues to the approach to treatment based on antidiuretic therapy.
journal_name
Clin Pediatr (Phila)journal_title
Clinical pediatricsauthors
Nørgaard JP,Djurhuus JCdoi
10.1177/0009922893032001s02subject
Has Abstractpub_date
1993-07-01 00:00:00pages
5-9eissn
0009-9228issn
1938-2707journal_volume
Spec Nopub_type
杂志文章,评审abstract::This retrospective cohort study aimed to describe antipyretic use among healthy patients in a pediatric emergency department (ED) with nonurgent fever defined as: triage level 4 or 5, chief complaint fever or temperature 38°C to 39°C, and otherwise normal vital signs, and determine if antipyretic administration is ass...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922817734356
更新日期:2018-06-01 00:00:00
abstract::The purpose of this study was to assess the relationship between the clinical findings before starting treatment and the development quotient in children treated for congenital hypothyroidism. Patients with congenital hypothyroidism (n = 129) were divided into favorable and unfavorable groups according to intellectual...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922806289326
更新日期:2007-01-01 00:00:00
abstract::An association between the frequency of otitis media in early childhood and later hyperactivity is reported in this study. The subjects were 67 children referred to a child development clinic for evaluation of school failure. Ranging from 6 to 13 years old, all the children demonstrated specific school learning proble...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600508
更新日期:1987-05-01 00:00:00
abstract::A descriptive analysis was done on 73 consecutive cases of childhood sexual abuse seen in 1978. There were conspicuous similarities among the cases. Sexually abused children tended to come from households with evidence of family stress. The events occurred in safe havens such as the childrens' own homes, by individual...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001901007
更新日期:1980-10-01 00:00:00
abstract::Two patients with acute osteomyelitis had technetium 99m methylene diphosphonate bone images that were misinterpreted. A review of six prospective evaluations of technetium scanning in the diagnosis of acute osteomyelitis shows that bone image interpretation may be misleading in five to seven per cent of pediatric pat...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001900904
更新日期:1980-09-01 00:00:00
abstract::In many countries, ibuprofen is available only in oral formulations. The authors aimed to investigate parental satisfaction and possible adverse reactions among children receiving newly marketed ibuprofen suppositories, prior to their arrival at the pharmaceutical points of distribution. Children needing antipyretic m...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922810384847
更新日期:2011-03-01 00:00:00
abstract::Three hundred eighty-six isolates of Propionibacterium sp. were recovered from 2,003 specimens studied for the identification of anaerobic bacteria in children during a 15-year period. Three hundred forty-three (89%) of these were Propionibacterium acnes. A total of 50 (13%) Propionibacterium isolates identified from ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289403300807
更新日期:1994-08-01 00:00:00
abstract::Five cases of bacterial epididymo-orchitis are presented. These patients demonstrate three distinct mechanisms of bacterial infection of the intrascrotal structures: epididymo-orchitis as a presentation and a complication of urinary tract infection; epididymo-orchitis associated with sexually transmitted disease; and ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288001901206
更新日期:1980-12-01 00:00:00
abstract::Nationally recommended universal lipid screening (ULS) in children aged 9 to 11 years is low. Little is known about parents' understanding of screening. We conducted a survey exploring parental knowledge and attitudes regarding ULS. Of 91 parent respondents, 81.3% were female, 69.2% were non-Hispanic white, 90.1% had ...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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journal_title:Clinical pediatrics
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更新日期:1988-01-01 00:00:00
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journal_title:Clinical pediatrics
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更新日期:1999-08-01 00:00:00
abstract::To understand why congenital dislocated hip (CDH) was diagnosed late (mean age: nine months) in children admitted to the Children's Hospital of Philadelphia (CHOP), 714 consecutive CHOP admissions, aged zero to two years, and 947 consecutive newborns delivered at the Hospital, University of Pennsylvania (HUP) were exa...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992287601500304
更新日期:1976-03-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289503401004
更新日期:1995-10-01 00:00:00
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journal_title:Clinical pediatrics
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更新日期:2004-09-01 00:00:00
abstract::The aim of this study was to document the changing clinical profile and prognosis of acute diarrhea in infants. This was a prospective observational study with follow-up. Demographic, anthropometric, and clinical data were collected in children younger than 1 year with acute diarrhea. Stool was examined under the micr...
journal_title:Clinical pediatrics
pub_type: 杂志文章
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更新日期:2007-10-01 00:00:00
abstract::Clinical and laboratory findings of Zellweger syndrome (ZS) patients diagnosed at King Faisal Specialist Hospital and Research Center (KFSH & RC), Riyadh, Saudi Arabia over a period of 10 years are presented in this report. Eleven patients (nine females and two males) from 2 to 4 months old were referred to KFSH & RC ...
journal_title:Clinical pediatrics
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更新日期:1999-02-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/000992288802700302
更新日期:1988-03-01 00:00:00
abstract::The aim of this integrative review is to investigate current literature regarding family health history (FHH) taking practices, attitudes, and challenges in the pediatric outpatient setting. FHH is a known clinical tool for providers; however, there are no explicit standards for pediatric FHH collection. The integrati...
journal_title:Clinical pediatrics
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doi:10.1177/0009922820943474
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abstract::Infections with Mycobacterium marinum are uncommon in children but should be considered by a physician confronted with chronic, poorly healing skin lesions. A case of such an infection in a 4-year-old child is presented. Presenting signs and symptoms, differential diagnosis, and treatment of these infections are discu...
journal_title:Clinical pediatrics
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doi:10.1177/000992288502400512
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journal_title:Clinical pediatrics
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journal_title:Clinical pediatrics
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journal_title:Clinical pediatrics
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journal_title:Clinical pediatrics
pub_type: 杂志文章,评审
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更新日期:2001-10-01 00:00:00
abstract::Childhood thyrotoxicosis is not an uncommon illness, but there is a considerable relapse rate in these patients on medical treatment. An attempt is made in this study to identify those markers that are predictive of a tendency to relapse in childhood thyrotoxicosis. A total of 32 patients with Graves disease were incl...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288702600306
更新日期:1987-03-01 00:00:00
abstract::Acute splenic sequestration crisis ( ASSC ), a common complication in homozygous sickle cell anemia, has been described infrequently in sickle-hemoglobin C (SC) disease in the absence of high altitude exposure. In this report, we describe three children with hemoglobin SC disease who developed episodes of ASSC that we...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992288402300612
更新日期:1984-06-01 00:00:00
abstract::In the young child, particularly those between the ages of 1 and 3 years, aerodigestive tract foreign bodies continue to be a significant problem. Early diagnosis and treatment can decrease morbidity and length of hospital stay in these children. Three cases of delayed diagnosis in children with bronchial (2) and esop...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992289803700605
更新日期:1998-06-01 00:00:00
abstract::Objectives. The available literature on pulmonary disease in pediatric inflammatory bowel disease is limited. We evaluated the prevalence of pulmonary manifestations in pediatric inflammatory bowel disease and their association with disease severity. Methods. Patients completed the St. George's Respiratory Questionnai...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922820910821
更新日期:2020-06-01 00:00:00
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journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/0009922809337530
更新日期:2009-11-01 00:00:00
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journal_title:Clinical pediatrics
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doi:10.1177/0009922818769469
更新日期:2018-10-01 00:00:00
abstract::The aim of this study was to evaluate the safety and efficacy of nonoperative treatment of esophageal perforation (EP) in children. Between 1999 and 2004, 13 episodes in 12 patients were evaluated. The treatment program consisted of broad-spectrum antibiotics, nasopharyngeal aspiration, parenteral and/or enteral nutri...
journal_title:Clinical pediatrics
pub_type: 杂志文章
doi:10.1177/000992280504400204
更新日期:2005-03-01 00:00:00