Factors underlying suboptimal childhood immunisation.

abstract：:In 2004, we conducted a study in Piemonte (Italy), in order to describe incidence, treatment, hospitalizations and costs of herpes zoster (HZ), in population over 14 years of age. Twenty-four regional general practitioners, with 26,394 patients >14 years in charge (0.71% of the regional population), reported prospecti...

journal_title：Vaccine

authors： Di Legami V,Gianino MM,Ciofi degli Atti M,Massari M,Migliardi A,Tomba GS,Zotti C,Zoster Study Group.

更新日期：2007-10-23 00:00:00

abstract：BACKGROUND:1-Dose varicella vaccination was recommended for children in Beijing before November 2012. To further control school-based outbreaks and decrease incidence, a 2-dose vaccination was implemented in 2013. We described the varicella epidemiology and assessed impact of the 2-dose vaccination in Haidian district,...

journal_title：Vaccine

authors： Fu J,Jiang C,Wang J,Zhao F,Ma T,Shi R,Zhao Y,Zhang X

更新日期：2017-04-25 00:00:00

abstract：:A pilot study compared the immune response of regular (0, 3, 6, 32 weeks) and extended (0, 10, 13, 32 weeks) schedules of the UK anthrax vaccine (anthrax vaccine precipitated, AVP). Concentrations of antibodies to protective antigen (PA) were higher (p<0.05) among recipients of the extended (n=7) versus regular schedu...

journal_title：Vaccine

authors： Hepburn MJ,Hugh Dyson E,Simpson AJ,Brenneman KE,Bailey N,Wilkinson L,Hornby R,Mateczun AJ,Bell MG,Baillie LW

更新日期：2007-08-10 00:00:00

abstract：:Since children with chronic diseases represent a primary target for immunization strategies, it is important that their immunization coverage and timeliness of vaccines is optimal. We performed a study to measure immunization coverage and timeliness of vaccines in children with type 1 diabetes, HIV infection, Down syn...

journal_title：Vaccine

authors： Pandolfi E,Carloni E,Marino MG,Ciofi degli Atti ML,Gesualdo F,Romano M,Giannattasio A,Guarino A,Carloni R,Borgia P,Volpe E,Perrelli F,Pizzuti R,Tozzi AE

更新日期：2012-07-20 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) is the etiological agent of a highly contagious disease that affects cloven-hoofed animal species. The FMDV capsid is highly acid labile and viral particles lose their immunogenicity when they disassemble at mildly acidic pHs. The viral capsid of FMDV serotype O is more sensitive th...

journal_title：Vaccine

authors： Xie Y,Li H,Qi X,Ma Y,Yang B,Zhang S,Chang H,Yin X,Li Z

更新日期：2019-03-28 00:00:00

abstract：PURPOSE:GEN-003 is a candidate therapeutic HSV-2 vaccine containing a fragment of infected cell protein 4 (ICP4.2), a deletion mutant of glycoprotein D2 (gD2ΔTMR), and Matrix-M2 adjuvant. In a dose-ranging phase 1/2a clinical trial, immunization with GEN-003 reduced viral shedding and the percentage of reported herpeti...

journal_title：Vaccine

authors： Flechtner JB,Long D,Larson S,Clemens V,Baccari A,Kien L,Chan J,Skoberne M,Brudner M,Hetherington S

更新日期：2016-10-17 00:00:00

abstract：PURPOSE:Meningococcal C conjugate vaccine was included in December 2000 in the Spanish childhood vaccination at 2, 4 and 6 months of age. In 2006, routine vaccination was modified to two doses at 2 and 4-6 months and a booster dose during the second year of age. Additionally, successive catch-up campaigns were launched...

journal_title：Vaccine

authors： Garrido-Estepa M,León-Gómez I,Herruzo R,Cano R

更新日期：2014-05-07 00:00:00

abstract：:The 2-1-1 rabies postexposure treatment schedule is an abbreviated regimen in which a tissue culture rabies vaccine is administered intramuscularly at two sites on day 0, and at one site on days 7 and 21. Compared to the standard five-dose intramuscular regimen, the 2-1-1 schedule reduces the number of clinic visits f...

journal_title：Vaccine

authors： Chutivongse S,Wilde H,Fishbein DB,Baer GM,Hemachudha T

更新日期：1991-08-01 00:00:00

abstract：:Parainfluenza virus type 1 (PIV1) is a major cause of croup in infants and young children, and a vaccine is needed to prevent the serious disease caused by this virus. In the present study, a live attenuated PIV1 vaccine candidate was generated by modification of the extensively-studied PIV3 cold-passaged (cp) cp45 va...

journal_title：Vaccine

authors： Skiadopoulos MH,Tao T,Surman SR,Collins PL,Murphy BR

更新日期：1999-10-14 00:00:00

abstract：BACKGROUND:Hepatitis B (HepB) vaccination is the most effective measure to prevent HBV infection. Routine HepB vaccination was recommended for infants in 1991 and catch-up vaccination has been recommended for adolescents since in 1995. The purpose of this study is to assess HepB vaccination among adolescents 13-17 year...

journal_title：Vaccine

authors： Lu PJ,Yankey D,Jeyarajah J,O'Halloran A,Elam-Evans L,Greby SM,Singleton JA,Murphy TV

更新日期：2015-04-08 00:00:00

abstract：:Virus-like particles (VLPs) are excellent tools for vaccines against pathogens and tumors. They can accommodate foreign polypeptides whose incorporation efficiency and immunogenicity however decrease strongly with the increase of their size. We recently described the CD8(+) T cell immune response against a small forei...

journal_title：Vaccine

authors： Sistigu A,Bracci L,Valentini M,Proietti E,Bona R,Negri DR,Ciccaglione AR,Tritarelli E,Nisini R,Equestre M,Costantino A,Marcantonio C,Santini SM,Lapenta C,Donati S,Tataseo P,Miceli M,Cara A,Federico M

更新日期：2011-04-18 00:00:00

abstract：:Rabies virus remains an important burden of disease claiming an estimated 60,000 lives each year, mainly children, and having a huge economical and societal cost. Post-exposure prophylaxis (PEP) is highly effective, however in patients that present with neurological symptoms the case-fatality ratio is extremely high (...

journal_title：Vaccine

authors： Jochmans D,Neyts J

更新日期：2019-08-02 00:00:00

abstract：:This study was undertaken to estimate the magnitude of Bordetella pertussis infections in a highly vaccinated population in Israel in order to evaluate the relationship between clinical notification data and serology-based evidence of infection. A cross-sectional survey was conducted on a total of 1982 serum samples f...

journal_title：Vaccine

authors： Rendi-Wagner P,Tobias J,Moerman L,Goren S,Bassal R,Green M,Cohen D

更新日期：2010-04-26 00:00:00

abstract：BACKGROUND:FP-01.1 is a novel synthetic influenza A vaccine consisting of six fluorocarbon-modified 35-mer peptides that encapsulate multiple CD4+ and CD8+ T-cell epitopes and is designed to induce an immune response across a broad population. METHODS:FP-01.1 was evaluated for safety and immunogenicity in a randomised...

journal_title：Vaccine

authors： Francis JN,Bunce CJ,Horlock C,Watson JM,Warrington SJ,Georges B,Brown CB

更新日期：2015-01-03 00:00:00

abstract：:Meningococcal disease is a serious medical condition that can prove fatal within hours in otherwise healthy individuals. Disease incidence is highest in infants, yet there is no broadly protective quadrivalent vaccine that covers this age group. A new investigational quadrivalent meningococcal glycoconjugate vaccine a...

journal_title：Vaccine

authors： Bröker M,Dull PM,Rappuoli R,Costantino P

更新日期：2009-09-18 00:00:00

abstract：:Previous studies with the malaria vaccine RTS,S/AS02(A) in young children in a malaria endemic area of Mozambique have shown it to have a promising safety profile and to reduce the risk of Plasmodium falciparum infection and disease. In this study, we assessed the antibody responses to the P. falciparum and hepatitis ...

journal_title：Vaccine

authors： Aide P,Dobaño C,Sacarlal J,Aponte JJ,Mandomando I,Guinovart C,Bassat Q,Renom M,Puyol L,Macete E,Herreros E,Leach A,Dubois MC,Demoitie MA,Lievens M,Vekemans J,Loucq C,Ballou WR,Cohen J,Alonso PL

更新日期：2011-08-11 00:00:00

abstract：:The calculation of p(epitope) values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the p(epitope) value to equine influenza vaccine strain selection was assessed. There was a negative correlation between p(epitope) value and vaccine efficacy ...

journal_title：Vaccine

authors： Daly JM,Elton D

更新日期：2013-12-09 00:00:00

abstract：:Protopanaxadiol saponins (Rg3, Rd, Rc, Rb1 and Rb2) and protopanaxatriol saponins (Rg1, Re and Rg2) isolated from the root of Panax ginseng C.A. Meyer were evaluated for their adjuvant effects on the immune responses to ovalbumin (OVA) in mice. BALB/c mice were subcutaneously injected twice at a 3-week interval with 1...

journal_title：Vaccine

authors： Sun J,Hu S,Song X

更新日期：2007-01-22 00:00:00

abstract：:Persistent infection by high risk genotypes of human papillomavirus (HPV) is the cause of cervical cancer, which remains one of the most common cancers among women worldwide. In addition, there is a growing appreciation that high risk HPVs are associated with a number of other cancers including anogenital cancers as w...

journal_title：Vaccine

authors： Wick DA,Webb JR

更新日期：2011-10-13 00:00:00

abstract：:Salmonellae are commonly isolated from dogs. The number of dogs infected with Salmonella spp. is surprisingly high and greater than the incidence of clinical disease would suggest. Salmonellosis is common in greyhound kennels. Morbidity can approach 100% in puppies and the mortality ranges to nearly 40%. To date, ther...

journal_title：Vaccine

authors： McVey DS,Chengappa MM,Mosier DE,Stone GG,Oberst RD,Sylte MJ,Gabbert NM,Kelly-Aehle SM,Curtiss R

更新日期：2002-02-22 00:00:00

abstract：:Streptococcus pneumoniae is an important pathogen worldwide. Accurate sampling of S. pneumoniae carriage is central to surveillance studies before and following conjugate vaccination programmes to combat pneumococcal disease. Any bias introduced during sampling will affect downstream recovery and typing. Many variable...

journal_title：Vaccine

authors： Gladstone RA,Jefferies JM,Faust SN,Clarke SC

更新日期：2012-11-06 00:00:00

abstract：:We successfully re-vaccinated hepatitis B virus (HBV) vaccine non-responders using a double dose of the combined hepatitis A virus (HAV) and HBV vaccine. The hope was to improve priming of hepatitis B surface antigen (HBsAg)-specific cell mediated immune response (CMI) by an increased antigen dose and a theoretical ad...

journal_title：Vaccine

authors： Nyström J,Cardell K,Björnsdottir TB,Fryden A,Hultgren C,Sällberg M

更新日期：2008-11-05 00:00:00

abstract：:Enterovirus 71 (EV71) causes seasonal epidemics of hand-foot-and-mouth disease associated with fatal neurological complications in young children, and several major outbreaks have occurred recently. This study developed an effective antiviral agent by transforming the gene for VP1 protein, a previously defined epitope...

journal_title：Vaccine

authors： Chen HF,Chang MH,Chiang BL,Jeng ST

更新日期：2006-04-05 00:00:00

abstract：:A phase III, randomized, double-blind study evaluated the efficacy, reactogenicity, safety and immunogenicity of a human rotavirus vaccine, RIX4414 in Japanese infants aged 6-14 weeks when administered as two doses (0, 1-month schedule). Efficacy against any and severe rotavirus gastroenteritis leading to medical inte...

journal_title：Vaccine

authors： Kawamura N,Tokoeda Y,Oshima M,Okahata H,Tsutsumi H,Van Doorn LJ,Muto H,Smolenov I,Suryakiran PV,Han HH

更新日期：2011-08-26 00:00:00

abstract：:Salmonella enterica serovar Typhimurium is a versatile host organism for the generation of recombinant live vaccines for mucosal immunization. We investigated the performance of an intracellular-activated promoter for expression of heterologous antigens by Salmonella carrier strains. We observed that intracellular exp...

journal_title：Vaccine

authors： Husseiny MI,Hensel M

更新日期：2005-04-08 00:00:00

abstract：:The objectives of this research were to evaluate the risk of prolonged testicular infection as a consequence of vaccination of peri-pubertal bulls with a modified-live, noncytopathic strain of BVDV and to assess vaccine efficacy in preventing prolonged testicular infections after a subsequent acute infection. Seronega...

journal_title：Vaccine

authors： Givens MD,Riddell KP,Walz PH,Rhoades J,Harland R,Zhang Y,Galik PK,Brodersen BW,Cochran AM,Brock KV,Carson RL,Stringfellow DA

更新日期：2007-01-15 00:00:00

abstract：:A safe, effective and accessible preventive vaccine is our best long-term hope for the control of the HIV/AIDS pandemic. The first phase I trial of an HIV vaccine was conducted in the US in 1987. Since then, >30 candidate vaccines have been tested in over 60 phase I/II clinical trials, involving >8000 healthy human vo...

journal_title：Vaccine

authors： Esparza J,Osmanov S,Pattou-Markovic C,Touré C,Chang ML,Nixon S

更新日期：2002-05-06 00:00:00

abstract：:The revised Standards for Adult Immunization Practice ("Standards"), published in 2014, recommend routine vaccination assessment, strong provider recommendation, vaccine administration or referral, and documentation of vaccines administered into immunization information systems (IIS). We assessed clinician and pharmac...

journal_title：Vaccine

authors： Granade CJ,Parker Fiebelkorn A,Black CL,Lutz CS,Srivastav A,Bridges CB,Ball SW,Devlin RG,Cloud AJ,Kim DK

更新日期：2020-07-14 00:00:00

abstract：:110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody. After 10 years, 99.09% of inoc...

journal_title：Vaccine

authors： Bian GL,Ma R,Dong HJ,Ni HX,Hu FJ,Chen YR,Chen JQ,Zhou SY,Lin YX,Xu GZ

更新日期：2010-07-05 00:00:00

abstract：:DNA vaccines might offer an alternative to the live smallpox vaccine in providing protective efficacy in an orthopoxvirus (OPV) lethal respiratory challenge model. BALB/c mice were immunised with DNA vaccines coding for 10 different single vaccinia virus (VACV) membrane proteins. After an intranasal challenge with the...

journal_title：Vaccine

authors： Pulford DJ,Gates A,Bridge SH,Robinson JH,Ulaeto D

更新日期：2004-09-03 00:00:00