Abstract:
:Modern nephrology developed in Poland mostly from the internal medicine department chaired in Warsaw by the great internist prof. Witold Orłowski (1874-1966). Three of his pupils Tadeusz Orłowski, Jan Roguski and Jakub Penson independently established the foundations of clinical nephrology and renal replacement therapy in different parts of Poland. T. Orłowski and his team worked in Warsaw, where despite developing clinical nephrology and dialysis also performed the first successful renal transplantation in Poland in 1966. Thereafter in 1975 the Institute of Transplantology in Warsaw was established and for several years was the leading research and education center in nephrology and transplantology. J. Penson established a sound clinical nephrology program in Gdańsk, where later physiological and biochemical aspects of the kidney were studied by his successors -- A. Manitius and B. Rutkowski in collaboration with S. Angielski and his biochemical team. They were instrumental in establishing a successful program leading to the development of dialysis in Poland during the last twenty years. J. Roguski in Poznań continued the research on water-electrolyte balance, metabolic and endocrine disturbances in renal patients and immunology of glomerular diseases. The first HD treatment was performed in Poznań in 1958 by the group of J. Roguski and coworkers chaired by K. Baczyk. Subsequently, several strong academic centers were established throughout Poland. F. Kokot in Katowice being himself leader of the Polish nephrology for many years created a very active centre well known for its pioneer publications on water- electrolyte, acid- base and endocrine disorders in different stages of chronic kidney disease. F. Kokot and his successor A. Wiecek are also very active and well recognized on an international scale. In Wrocław a nephrological center was established by Z. Wiktor and later his coworkers Z. Szewczyk and recently M. Klinger. Other valuable academic nephrological centers were created in Kraków (Z. Hanicki, W. Sułowicz), Lublin (Z. Twardowski, A. Ksiazek), Łódź (Z. Orłowski, W. Chrzanowski), Bydgoszcz (A. Nartowicz, J. Manitius) and later Białystok (M. Myśliwiec), and others. Simultaneously strong academic units were formed in the military hospitals-Łódź (K. Trznadel, M. Luciak) and Warsaw (Z. Wańkowicz). The last center was for many years widely known for their studies concerning PD treatment. Pediatric nephrology developed in parallel with adult centers mainly in Warsaw (T. Wyszńska, M. Sieniawska, R. Grenda), Wrocław (Z. Morawska, D. Zwoliska) and Gdańsk (M. Uszycka-Karcz, A Zurowska). Several Polish nephrologists were and still are involved in the activity of European and international nephrological societies.
journal_name
J Nephroljournal_title
Journal of nephrologyauthors
Czekalski S,Rutkowski Bsubject
Has Abstractpub_date
2006-05-01 00:00:00pages
S150-8eissn
1121-8428issn
1724-6059journal_volume
19 Suppl 10pub_type
历史文章,杂志文章abstract:BACKGROUND AND METHODS:Smoking is associated with hyperparathyroidism in the elderly general population and nicotine, the main component of tobacco smoke, stimulates PTH release in experimental models. Although smoking is a persisting problem in patients with end-stage renal disease (ESRD), the association between smok...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/JN.2011.7740
更新日期:2012-01-01 00:00:00
abstract::Hemolytic uremic syndrome (HUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. It is usually secondary to infections by strains of Escherichia coli (STEC) that produce Shiga-like toxin. In about 10% of patients, no STEC infections are reported. In these ...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.5301/jn.5000146
更新日期:2012-11-01 00:00:00
abstract::Minoxidil is frequently used in patients with advanced renal disease who have been unresponsive to other antihypertensive agents. We describe a case of a 50-year-old man with chronic renal failure who was hospitalized complaining of a 2-week history of sore throat that had progressed to severe oral lesions and multipl...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:In the general population and in hemodialysis patients epicardial adipose tissue (EAT) has been associated with increased mortality and cardiovascular events. Weight loss and lipid lowering therapies reduced EAT in the general population. It is unknown whether sevelamer, a phosphate (Pi) binder that lowers c...
journal_title:Journal of nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s40620-016-0310-9
更新日期:2016-10-01 00:00:00
abstract::The abnormal metabolism of uric acid results in many disease such as chronic kidney disease, hyperuricemia, nephrolithiasis, gout, hypertension, vascular disease and so on. Serum uric acid levels are maintained by the balance between production and elimination. There are many factors that maintain the balance of serum...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-018-0546-7
更新日期:2019-04-01 00:00:00
abstract::The relevance of the Salerno Medical School is examined through the contributions of Magister Maurus, Alfano I, Giovanni Plateario, Giovanni Afflacio, Bartolomeo and Urso of Calabria. An unpublished treatise on De Urinis in middlelatin and Italian volgare is introduced here for the first time by discussing the lapis o...
journal_title:Journal of nephrology
pub_type: 历史文章,杂志文章
doi:
更新日期:2004-03-01 00:00:00
abstract::Highly concentrated marine polyunsaturated fatty acids (n-3 PUFA), affecting the lipids and lipophilic drugs metabolism, can interfere with cyclosporine (CyA) pharmacokinetics. This prospective, randomized and placebo-controlled, double-blind study involved 42 kidney graft recipients. From day +1, 21 pts (E) received ...
journal_title:Journal of nephrology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-03-01 00:00:00
abstract::Sarcoidosis is a multisystem disorder of unknown etiology, which may occur in all tissues and organs of the body. Clinical presentation may be quite variable and affected by race. The most commonly affected system is the lungs with >95% of patients displaying such involvement. Renal involvement is uncommon (<2%) and m...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Gut-derived uremic toxins have been associated with adverse outcomes in chronic kidney disease (CKD). Alterations in bowel habits, including constipation, seem to play an additional role in uremic toxicity. The aim of this study is to investigate the association of bowel habits with gut-derived uremic toxins...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-020-00819-9
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Lipid peroxidation (LPO) plays a role in glomerulonephritis pathogenesis. The role of LPO in IgA nephropathy (IgAN) and the effect of prostaglandin E1 on it, is not determined. METHODS:Levels of malondialdehyde (MDA), superoxide dismutase (SOD) and vitamin E (vitE) were measured in 42 patients with IgAN and...
journal_title:Journal of nephrology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2005-05-01 00:00:00
abstract:INTRODUCTION:Medullary cystic kidney disease type 1 (MCKD1; OMIM #174000) is a familial progressive tubule-interstitial nephropathy belonging to the recently defined group of autosomal dominant tubulointerstitial kidney diseases (ADTKD). CASE REPORT:A specific type of cytosine insertion in the extracellular variable n...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-016-0282-9
更新日期:2016-06-01 00:00:00
abstract::Toll-like receptors (TLRs) are a class of receptors of the innate immune system which detect pathogen-associated and danger-associated molecular patterns in order to initiate an inflammatory response. TLR2 and TLR4 downward signaling causes the production of proinflammatory cytokines that can induce insulin resistance...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-017-0432-8
更新日期:2017-12-01 00:00:00
abstract::The most common cause of liver disease worldwide is now non-alcoholic fatty liver disease (NAFLD). NAFLD refers to a spectrum of disease ranging from steatosis to non-alcoholic steatohepatitis, causing cirrhosis, and ultimately hepatocellular carcinoma. However, the impact of NAFLD is not limited to the liver. NAFLD h...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-020-00751-y
更新日期:2020-05-21 00:00:00
abstract::Lupus is now regarded as a syndrome which results from several related auto-immune processes, although the exact mechanisms of how the disease arises in susceptible individuals remain obscure. When the San Carlo meetings began in 1968, much less was known about the pathogenesis of autoimmunity, but the presence of aut...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:1999-07-01 00:00:00
abstract::We report a unusual case of idiopathic nodular glomerulosclerosis mimicking changes that develop in diabetic nephropathy. A 66-year-old non-diabetic female developed nephrotic range proteinuria and the work up was unremarkable. Light and electron microscopy showed mesangial expansion with Kimmelsteil-Wilson nodules an...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2005-09-01 00:00:00
abstract::Gitelman syndrome (GS), an inherited disorder due to loss of function in mutations of the gene encoding the distal convoluted tubule Na-Cl cotransporter (NCCT), is characterized by hypokalemia metabolic alkalosis, hypomagnesemia and hypocalciuria. A 18-year-old girl was admitted to our hospital with a history of muscl...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2010-09-01 00:00:00
abstract:INTRODUCTION:Lack of adherence may influence the efficiency of phosphate binders. Our clinical hypothesis was that if lanthanum carbonate (LC) might offer some advantage over sevelamer (S), that that would be in those patients in whom serum phosphate (P) levels were not controlled by S or in those requiring high doses ...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:This study was undertaken to examine whether there is an association between parity and age at first birth and risk of death from chronic renal failure (CRF). STUDY DESIGN:Prospective cohort study. SETTING AND PARTICIPANTS:The study cohort consisted of 1 292 462 women who had a first and singleton childbir...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/jn.5000171
更新日期:2013-03-01 00:00:00
abstract::In this paper we concentrate on the role of infections in IgA nephropathy both from a pathogenetic and clinic point of view. The current hypotheses as regards the role of infections in the pathogenesis of IgA nephropathy are: (a) role of particular pathogens, (b) chronic exposure to mucosal infections, (c) abnormal ha...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:10.1007/s40620-016-0265-x
更新日期:2016-08-01 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is an important risk factor for all-cause mortality. In the general population, physical activity is associated with reduced mortality. We examined the association of level of physical activity with mortality in patients with predominantly nondiabetic CKD stage 3-4. METHODS:We s...
journal_title:Journal of nephrology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Reduced bone mineral density (BMD) is common in end-stage renal disease (ESRD) patients and predicts outcomes. The chronic kidney disease-mineral bone disorder contributes to low BMD in ESRD; however, the impact of classical risk factors for osteoporosis in the general population, such as body weight and fat...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/jn.5000185
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND AND AIMS:It has been well documented that gene and DNA alterations occur frequently in benign primary parathyroid adenomas as well as in parathyroid glands with secondary hyperplasia. However, it has not been shown whether a correlation exists between somatic DNA aberrations and clinical data. METHODS:We an...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::Chronic renal failure (CRF) is associated with a 20-fold increased risk of cardiovascular death, two principal mechanisms being: sudden, arrhythmic death associated with left ventricular hypertrophy, and ischaemic heart disease, associated with accelerated atherosclerosis. In recent years, the vascular endothelium has...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:An increased number of major histocompatibility complex (MHC) class II-positive cells (OX-6+ cells) were observed in the glomerulus and periglomerular interstitium during the course of anti-glomerular basement membrane (anti-GBM) crescentic glomerulonephritis (GN) in WKY rats. This study aimed to demonstrate...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Contrast-induced nephropathy (CI-AKI) is a complication of diagnostic/therapeutic hemodynamic procedures in cardiology, which may also cause renal cholesterolinic atheroembolism. Despite the severe clinical impact of these complications, there is no optimal therapy for preventing and treating them. We sugge...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/jn.5000266
更新日期:2013-05-01 00:00:00
abstract::Inherited distal renal tubular acidosis (dRTA) is caused by impaired urinary acid excretion resulting in hyperchloremic metabolic acidosis. Although the glomerular filtration rate (GFR) is usually preserved, and hypertension and overt proteinuria are absent, it has to be considered that patients with dRTA also suffer ...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-016-0370-x
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To investigate the pregnancy outcomes for patients with stage 3-4 chronic kidney disease (CKD) and the effects of pregnancy on kidney function. METHODS:Clinical data of pregnant women with CKD in the Peking University First Hospital between January 1st 2005 and October 1st 2016 were retrospectively analysed....
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.1007/s40620-018-0509-z
更新日期:2018-12-01 00:00:00
abstract::Chyluria results from an abnormal connection between lymphatic bed and urinary tract, causing lymph leakage into the urine. The clinical picture often begins with the appearance of cloudy, milky urines accompanied by monolateral flank pain, malnutrition, weight loss and weakness. We report a case of chyluria that occu...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:10.5301/JN.2011.8355
更新日期:2011-09-01 00:00:00
abstract::Cyclosporine (CsA) is among the most widely used immunosuppressants for preventing graft rejection and autoimmune diseases. However, its clinical use is hampered by its significant nephrotoxicity and effects as a cause of hypertension. The proximal tubular Na+-H+ exchanger (NHE3) is responsible for transcellular reabs...
journal_title:Journal of nephrology
pub_type: 杂志文章,评审
doi:
更新日期:2010-11-01 00:00:00
abstract::Henoch-Schonlein purpura is a clinical syndrome characterized by the association of skin, joint, and gastrointestinal symptoms. Henoch-Schonlein purpura is characterized by wide-spread vasculitis. Although the clinical symptoms of this disease are characteristic, the diagnosis is not always easy to establish because o...
journal_title:Journal of nephrology
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00