Effects of nifedipine on psychosis and tardive dyskinesia in schizophrenic patients.

abstract：:Medication nonadherence in severe mental disorders is an important clinical issue, but estimates vary between studies. There is a need for valid self-reports for both research and clinical practice. This study examined the level of adherence to prescribed medication in outpatients with severe mental disorders and eval...

journal_title：Journal of clinical psychopharmacology

authors： Jónsdóttir H,Opjordsmoen S,Birkenaes AB,Engh JA,Ringen PA,Vaskinn A,Aamo TO,Friis S,Andreassen OA

更新日期：2010-04-01 00:00:00

abstract：:Disordered water balance, or polydipsia, is an underassessed and underreported phenomenon present in the severely psychiatrically disabled population. Prevalence rates for polydipsia range from 6.2 to 20%. We followed up five male patients (mean age 43) with chronic schizophrenia who met the Kane criteria for being tr...

journal_title：Journal of clinical psychopharmacology

authors： Fuller MA,Jurjus G,Kwon K,Konicki PE,Jaskiw GE

更新日期：1996-08-01 00:00:00

abstract：:Little is known about the association between antidepressant treatment-emergent adverse events and symptom nonremission in major depressive disorder. The objective of the current analysis was to determine whether particular baseline symptoms or treatment-emergent symptoms (adverse events) during the first 2 weeks are ...

journal_title：Journal of clinical psychopharmacology

authors： Daly EJ,Trivedi MH,Fava M,Shelton R,Wisniewski SR,Morris DW,Stegman D,Preskorn SH,Rush AJ

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:This prospective study sought to compare the acute effects of haloperidol, amisulpride, and quetiapine on serum markers of bone formation and resorption in relatively young patients with minimal previous exposure to antipsychotic drugs. METHODS:Patients included in the study were randomly assigned to receive...

journal_title：Journal of clinical psychopharmacology

authors： Liang Y,Su YA,Zhao ZG,Gao N,Huang JZ,Tang MQ,Li KQ,Yang FD,Yu X,Si TM

更新日期：2015-10-01 00:00:00

abstract：:Valproic acid (VPA) has been used for decades in the treatment of epilepsy and psychiatric disorders, and the long-term use of VPA is regularly accompanied by hematological toxicity, including neutropenia. More recently, it has been demonstrated that VPA can be used as a histone deacetylase inhibitor (HDACi) for the t...

journal_title：Journal of clinical psychopharmacology

authors： Bartels M,van Solinge WW,den Breeijen HJ,Bierings MB,Coffer PJ,Egberts TC

更新日期：2012-12-01 00:00:00

abstract：:As many as 45% of patients with major depression also meet diagnostic criteria for bipolar (BP) II disorder. Although the use of a concurrent mood-stabilizing drug has been suggested in treating BP II depression, antidepressant monotherapy has received less attention. The efficacy and safety of venlafaxine were examin...

journal_title：Journal of clinical psychopharmacology

authors： Amsterdam J

更新日期：1998-10-01 00:00:00

abstract：:The aim of this study was to investigate whether obsessive-compulsive patients previously treated successfully with clomipramine or fluvoxamine could tolerate reduction of the daily dosage without worsening of the clinical condition. Thirty informed obsessive-compulsive patients, given a diagnosis according to DSM-III...

journal_title：Journal of clinical psychopharmacology

authors： Mundo E,Bareggi SR,Pirola R,Bellodi L,Smeraldi E

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:This study investigated extended release quetiapine (quetiapine XR) associated changes in functional MRI (fMRI) measures of task-induced amygdalar activation and resting state connectivity in anxious unipolar major depressive disorder (AMDD). METHODS:Anxious unipolar major depressive disorder patients (n = ...

journal_title：Journal of clinical psychopharmacology

authors： Altinay M,Karne H,Beall E,Anand A

更新日期：2016-12-01 00:00:00

abstract：:Unlike many other areas of medicine, psychiatric clinical trials have no gold standard laboratory tests with which to measure drug effects. Although reliable and valid psychometric measures are available, the standard analysis of such measures obscures the clinical relevance of drug effects. In this study, the authors...

journal_title：Journal of clinical psychopharmacology

authors： Faraone SV,Biederman J,Spencer TJ,Wilens TE

更新日期：2000-12-01 00:00:00

abstract：:The aims of this study were to examine whether pindolol, a serotonin (5-hydroxytryptamine [5-HT])-1A receptor antagonist, and mianserin, a 5-HT2A/C and alpha2-adrenoceptor (alpha2-AR) antagonist, may augment the clinical efficacy of fluoxetine, a selective serotonin reuptake inhibitor, and shorten the latency of onset...

journal_title：Journal of clinical psychopharmacology

authors： Maes M,Libbrecht I,van Hunsel F,Campens D,Meltzer HY

更新日期：1999-04-01 00:00:00

abstract：:Single oral doses (5 mg) of haloperidol were administered to 36 healthy men (26 black, 10 white) of whom 28 (22 black, 6 white) completed the study. Plasma samples harvested over 96 hours were analyzed for haloperidol and reduced haloperidol by means of a new high performance liquid chromatographic method. Reduced hal...

journal_title：Journal of clinical psychopharmacology

authors： Midha KK,Chakraborty BS,Ganes DA,Hawes EM,Hubbard JW,Keegan DL,Korchinski ED,McKay G

更新日期：1989-04-01 00:00:00

abstract：:The cholinergic-adrenergic balance hypothesis of affective disorders suggests that, in the areas of the brain that regulate mood, depression may represent a relative predominance of central cholinergic tone over adrenergic tone and that mania may represent the converse. Currently, converging lines of investigation fro...

journal_title：Journal of clinical psychopharmacology

authors： Risch SC,Kalin NH,Janowsky DS

更新日期：1981-07-01 00:00:00

abstract：:The clinical features and pharmacokinetics of 22 lithium overdoses are described. Effectiveness of different treatment regimens regarding elimination of lithium is discussed. Origin of overdose was due to deliberate poisoning or precipitated by concomitant diseases, coadministration of drugs, or combination of both. T...

journal_title：Journal of clinical psychopharmacology

authors： Eyer F,Pfab R,Felgenhauer N,Lutz J,Heemann U,Steimer W,Zondler S,Fichtl B,Zilker T

更新日期：2006-06-01 00:00:00

abstract：:Adverse events during selective serotonin reuptake inhibitor (SSRI) treatment are frequent and may lead to premature treatment discontinuation. If attrition is associated with early worsening of adverse effects or the frequency, intensity, or burden of adverse effects, interventions to maximize retention could be focu...

journal_title：Journal of clinical psychopharmacology

authors： Warden D,Trivedi MH,Wisniewski SR,Kurian B,Zisook S,Kornstein SG,Friedman ES,Miyahara S,Leuchter AF,Fava M,Rush AJ

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:This post hoc meta-analysis evaluated the efficacy and safety of desvenlafaxine 50 and 100 mg versus placebo across age groups and severity of depression at baseline in patients with major depressive disorder. METHODS:Data from placebo and desvenlafaxine 50-mg and 100-mg dose arms were pooled from 9 short-term...

journal_title：Journal of clinical psychopharmacology

authors： Mosca D,Zhang M,Prieto R,Boucher M

更新日期：2017-04-01 00:00:00

abstract：:Drug-associated extrapyramidal symptoms (EPS) in people with intellectual disability (ID) may be difficult to recognize, and clinicians' assessments may be hampered by lack of patients' capacities to adequately cooperate and by lack of reliable instruments to measure EPS in this population. Therefore, we compared asse...

journal_title：Journal of clinical psychopharmacology

authors： de Kuijper GM,Hoekstra PJ

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Bipolar disorder (BPD) is a chronic and recurrent mood disorder characterized by episodes of mania, hypomania, and major depression. Based on available evidence, mitochondrial dysfunction, oxidative stress, and inflammation have important roles in the pathophysiology of bipolar depression. More specifically,...

journal_title：Journal of clinical psychopharmacology

authors： Mehrpooya M,Yasrebifar F,Haghighi M,Mohammadi Y,Jahangard L

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Pharmacogenetic studies on clozapine (CLZ) have provided meaningful insights but have shown redundancies owing to wide interindividual variability and insufficient replication. The present study was designed to validate hitherto suggested candidate genes on CLZ pharmacokinetics and pharmacodynamics and explor...

journal_title：Journal of clinical psychopharmacology

authors： Lee ST,Ryu S,Kim SR,Kim MJ,Kim S,Kim JW,Lee SY,Hong KS

更新日期：2012-08-01 00:00:00

abstract：:Many drugs, including alcohol and stimulants, demonstrably increase sociability and verbal interaction and are recreationally consumed in social settings. One drug, 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), seems to produce its prosocial effects by increasing plasma oxytocin levels, and the oxytocin system ha...

journal_title：Journal of clinical psychopharmacology

authors： Bershad AK,Kirkpatrick MG,Seiden JA,de Wit H

更新日期：2015-06-01 00:00:00

abstract：:The selection of appropriate subjects is a critical element of successful clinical trials. Failure to properly identify, select, and retain subjects in clinical trials of antidepressant medications may affect the ability to show separation from placebo. Little is known about which type of site, academic or nonacademic...

journal_title：Journal of clinical psychopharmacology

authors： Dording CM,Dalton ED,Pencina MJ,Fava M,Mischoulon D

更新日期：2012-02-01 00:00:00

abstract：:Nitrous oxide (laughing gas) has shown early promise as a rapidly acting antidepressant in patients with treatment-resistant major depression and is currently investigated in several clinical trials. Because nitrous oxide is rarely administered outside operating rooms or dental practices, most psychiatrists are not fa...

journal_title：Journal of clinical psychopharmacology

authors： Nagele P,Zorumski CF,Conway C

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Some studies have shown that low dose of neuroleptic addition to ongoing antiobsessive treatment might be effective in treatment resistant obsessive-compulsive disorder (OCD). The primary purpose of this study was to evaluate the efficacy of low-dose quetiapine in clomipramine and serotonin reuptake inhibito...

journal_title：Journal of clinical psychopharmacology

authors： Sevincok L,Topuz A

更新日期：2003-10-01 00:00:00

abstract：:The long-term use of the serotonin-releaser and uptake-inhibitor 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") has been associated with memory impairments and increased liability to depressive mood and anxiety attacks. It is unclear, however, whether these psychologic deviations are reflected in alterations of t...

journal_title：Journal of clinical psychopharmacology

authors： Gamma A,Buck A,Berthold T,Vollenweider FX

更新日期：2001-02-01 00:00:00

abstract：:On the basis of a previous report suggesting the effectiveness of the beta-adrenoceptor/5-HT1A antagonist pindolol to accelerate the antidepressant effect of a selective serotonin reuptake inhibitor (SSRI) and to produce a therapeutic effect in drug-resistant depressed patients, these open studies were undertaken to f...

journal_title：Journal of clinical psychopharmacology

authors： Blier P,Bergeron R

更新日期：1995-06-01 00:00:00

abstract：:Many factors obscure the diagnosis of psychogenic disorders, especially anxiety and depression. The factors involved include an overlap of symptoms, discrepancies in diagnostic criteria, and the unreliability of self- and observer-reporting. Differentiation among the various personality disorders is, however, extremel...

journal_title：Journal of clinical psychopharmacology

authors： Cloninger CR

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:The combination of olanzapine and valproic acid (VPA) is regularly prescribed in the treatment of bipolar or schizoaffective disorders. The VPA has been shown to reduce olanzapine concentration, but the mechanism behind this interaction remains unknown. We aimed to investigate the effect of VPA on olanzapine...

journal_title：Journal of clinical psychopharmacology

authors： Tveito M,Smith RL,Høiseth G,Molden E

更新日期：2019-11-01 00:00:00

abstract：:Methamphetamine has become a major public health issue globally, particularly in the United States. Despite this, no effective pharmacotherapy for methamphetamine abuse has been developed to date. This 6-week, open-label pilot clinical trial examined the safety and tolerability of modafinil up to 400 mg/d in 8 methamp...

journal_title：Journal of clinical psychopharmacology

authors： McGaugh J,Mancino MJ,Feldman Z,Chopra MP,Gentry WB,Cargile C,Oliveto A

更新日期：2009-10-01 00:00:00

abstract：:The correlation between vitamin D deficiency and depression has recently been put forward and resulted in controversial findings. The present study was conducted to find out the effect of 2 single injections of 150,000 and 300,000 IU of vitamin D on improving the depression in depressed patients with vitamin D deficie...

journal_title：Journal of clinical psychopharmacology

authors： Mozaffari-Khosravi H,Nabizade L,Yassini-Ardakani SM,Hadinedoushan H,Barzegar K

更新日期：2013-06-01 00:00:00

abstract：:The therapeutic spectrum of nemonapride, a new substituted benzamide, and its relationship with plasma concentrations of the drug and prolactin were investigated by a fixed-dose study (18 mg/day for 3 weeks) in 31 patients with acutely exacerbated schizophrenia. Of 31 patients, 25 (80.6%) were responders who showed a ...

journal_title：Journal of clinical psychopharmacology

authors： Kondo T,Mihara K,Yasui N,Nagashima U,Ono S,Kaneko S,Ohkubo T,Osanai T,Sugawara K,Otani K

更新日期：2000-08-01 00:00:00

abstract：:Despite a recognized need for the inclusion of women of childbearing age in drug studies, many such studies include only men. This practice is due mainly to the added risk of teratogenicity and to cyclic variations in the menstrual phase and hormonal state. The methodological and ethical problems associated with drug ...

journal_title：Journal of clinical psychopharmacology

authors： Halbreich U,Carson SW

更新日期：1989-10-01 00:00:00