Acute Effects of Haloperidol, Amisulpride, and Quetiapine on Bone Turnover Markers in Patients With Schizophrenia.

abstract：:Case reports of a lithium-ketorolac drug interaction have been published, but no formal investigation of this interaction has been conducted. The objective of the study presented here was to determine significant changes in lithium serum and red blood cell (RBC) concentrations after lithium and ketorolac (oral formula...

journal_title：Journal of clinical psychopharmacology

authors： Cold JA,ZumBrunnen TL,Simpson MA,Augustin BG,Awad E,Jann MW

更新日期：1998-02-01 00:00:00

abstract：:Despite a recognized need for the inclusion of women of childbearing age in drug studies, many such studies include only men. This practice is due mainly to the added risk of teratogenicity and to cyclic variations in the menstrual phase and hormonal state. The methodological and ethical problems associated with drug ...

journal_title：Journal of clinical psychopharmacology

authors： Halbreich U,Carson SW

更新日期：1989-10-01 00:00:00

abstract：:The 2-mg dexamethasone suppression test (DST), performed in a drug-free acute exacerbation phase of illness shortly after admission, differentiated between major depression with psychosis and stringently diagnosed chronic schizophrenia. This has practical significance because effective drug treatment in each diagnosti...

journal_title：Journal of clinical psychopharmacology

authors： Clower CG

更新日期：1986-12-01 00:00:00

abstract：:The aim of this article was to analyze systematically literature information published in English (between 1966 and January 2011) on the efficacy of antidepressants in pediatric obsessive-compulsive disorder. Data were identified through different databases by using variously combined patterns of search terms. Searche...

journal_title：Journal of clinical psychopharmacology

authors： Gentile S

更新日期：2011-10-01 00:00:00

abstract：:Minority women often have a unique set of beliefs and expectations about medical treatment. At this time, there is a dearth of research looking at how depressed minority women respond to pharmacological interventions for the sexual concomitants of depression. This was the first study to examine the impact of a medicat...

journal_title：Journal of clinical psychopharmacology

authors： Dobkin RD,Menza M,Marin H,Allen LA,Rousso R,Leiblum SR

更新日期：2006-02-01 00:00:00

abstract：:The study presented here compared the acute performance-impairing, subject-rated, and observer-rated effects of quazepam (15, 30, and 45 mg), triazolam (0.1875, 0.375, and 0.5625 mg), zolpidem (7.5, 15, and 22.5 mg), and placebo in nine healthy, non-drug-abusing humans. Quazepam, a trifluoroethylbenzodiazepine, was ch...

journal_title：Journal of clinical psychopharmacology

authors： Rush CR,Armstrong DL,Ali JA,Pazzaglia PJ

更新日期：1998-04-01 00:00:00

abstract：:Lithium is clinically available for the treatment of mood disorders. However, it has remained unclear how lithium acts on the brain to produce its effects. The aim of this study was to evaluate the effects of chronic lithium on human brain activity using positron emission tomography and clarify the correlation between...

journal_title：Journal of clinical psychopharmacology

authors： Kohno T,Shiga T,Toyomaki A,Kusumi I,Matsuyama T,Inoue T,Katoh C,Koyama T,Tamaki N

更新日期：2007-12-01 00:00:00

abstract：:We compared acute effects of single intravenous administrations of metoclopramide (40 mg) and placebo in a double-blind crossover study involving 81 patients with tardive dyskinesia. Metoclopramide produced significantly greater reduction in mean total Abnormal Involuntary Movement Scale score as well as in ratings fo...

journal_title：Journal of clinical psychopharmacology

authors： Doongaji DR,Jeste DV,Jape NM,Sheth AS,Apte JS,Vahia VN,Desai AB,Parikh MD,Rathi LG,Ghandi MH,Parikh RM,Thatte S,Bharadwaj J

更新日期：1982-12-01 00:00:00

abstract：PURPOSE/BACKGROUND:The purpose of this study was to examine the relationships between ytochrome P450 family 2 subfamily C member 19 (CYP2C19) polymorphisms, brain-derived neurotrophic factor (BDNF) plasma levels, and treatment responses to escitalopram in Chinese patients with panic disorder (PD). METHODS/PROCEDURES:N...

journal_title：Journal of clinical psychopharmacology

authors： He Q,Mei Y,Liu Y,Yuan Z,Zhang J,Yan H,Shen L,Zhang Y

更新日期：2019-03-01 00:00:00

abstract：:There have been many attempts to find predictors of the therapeutic response to the clomipramine treatment of obsessive-compulsive disorder. The majority of studies have failed to identify such predictors. Possible reasons for this failure include the small sample size of most studies, samples homogeneous with respect...

journal_title：Journal of clinical psychopharmacology

authors： Ackerman DL,Greenland S,Bystritsky A,Morgenstern H,Katz RJ

更新日期：1994-08-01 00:00:00

abstract：PURPOSE/BACKGROUND:Many investigators reported that pharmacological treatment of female sexual dysfunction (FSD) has been a promising field yet to be explored. The purpose of this pilot study was to investigate the efficacy and safety of a topical cream containing small concentrations of three vasodilators with differe...

journal_title：Journal of clinical psychopharmacology

authors： Gomaa AA,Abdel Aziz NM,Thabet RH,Fouly HA,Altellawy SH,Gomaa GA

更新日期：2018-02-01 00:00:00

abstract：:It was predicted that tiaspirone, a novel compound, would benefit schizophrenic patients since in animal experiments it is a potent dopamine blocker. Following a placebo washout period of 1 to 2 weeks, 14 patients were treated for 28 days with the drug in a single-blind, dose ranging trial. GAS, NOSIE, and BPRS scores...

journal_title：Journal of clinical psychopharmacology

authors： Moore NC,Meyendorff E,Yeragani V,LeWitt PA,Gershon S

更新日期：1987-04-01 00:00:00

abstract：:This study evaluated the impact of using long-acting injectable (LAI) antipsychotics for a longer treatment duration versus a short duration on health care resource utilization among Medicaid-insured schizophrenia patients. Schizophrenia patients 13 years or older initiating LAI antipsychotics were identified from the...

journal_title：Journal of clinical psychopharmacology

authors： Bera R,Offord S,Zubek D,Lau G,Lin J,Karson C

更新日期：2014-02-01 00:00:00

abstract：:Serotonin uptake inhibitors are generally considered activating antidepressants. To assess rates and temporal patterns of activation and sedation as well as dose-effect relationships, adverse event data were evaluated from a fixed-dose study comparing placebo and fluoxetine 5, 20, and 40 mg/day in the treatment of maj...

journal_title：Journal of clinical psychopharmacology

authors： Beasley CM Jr,Sayler ME,Weiss AM,Potvin JH

更新日期：1992-10-01 00:00:00

abstract：:The aim of the study was to determine whether baseline pain was associated with discernible clinical features and treatment outcomes for patients with major depressive disorder (MDD) receiving 6-week fluoxetine treatment. A total of 131 inpatients with acutely ill MDD were enrolled to receive 20 mg of fluoxetine daily...

journal_title：Journal of clinical psychopharmacology

authors： Lin HS,Wang FC,Lin CH

更新日期：2015-12-01 00:00:00

abstract：:The potential for iloperidone, a D2/5-HT2A antipsychotic, to affect the heart rate-corrected QT interval (QTc) was assessed in the absence and presence of metabolic inhibitors in a randomized, open-label, multicenter study. QT interval prolongation by medications, including both conventional and atypical antipsychotic...

journal_title：Journal of clinical psychopharmacology

authors： Potkin SG,Preskorn S,Hochfeld M,Meng X

更新日期：2013-02-01 00:00:00

abstract：:Paroxetine is a novel phenylpiperidine antidepressant agent that acts as a potent and selective inhibitor of serotonin reuptake. We report results of a 6-week, randomized, double-blind, multicenter study comparing paroxetine and fluoxetine in the treatment of major depression. One hundred seventy-eight inpatients, who...

journal_title：Journal of clinical psychopharmacology

authors： Tignol J

更新日期：1993-12-01 00:00:00

abstract：:Hyperprolactinemia mediated by antagonism of dopaminergic neurotransmission in the pituitary gland is a common adverse effect of antipsychotics. Recent studies have suggested that polymorphisms of dopamine receptors can affect the therapeutic response to antipsychotics. Thus, our aim was to evaluate whether 2 such pol...

journal_title：Journal of clinical psychopharmacology

authors： López-Rodríguez R,Román M,Novalbos J,Pelegrina ML,Ochoa D,Abad-Santos F

更新日期：2011-10-01 00:00:00

abstract：:A double-blind, placebo-controlled trial was performed to determine the efficacy and tolerability of 8 weeks of treatment with risperidone in the management of 48 adolescent and adult patients with Tourette syndrome. Twenty-four patients were randomly assigned to treatment with risperidone in doses of 0.5 to 6.0 mg/da...

journal_title：Journal of clinical psychopharmacology

authors： Dion Y,Annable L,Sandor P,Chouinard G

更新日期：2002-02-01 00:00:00

abstract：:As many as 45% of patients with major depression also meet diagnostic criteria for bipolar (BP) II disorder. Although the use of a concurrent mood-stabilizing drug has been suggested in treating BP II depression, antidepressant monotherapy has received less attention. The efficacy and safety of venlafaxine were examin...

journal_title：Journal of clinical psychopharmacology

authors： Amsterdam J

更新日期：1998-10-01 00:00:00

abstract：:The Taq1A polymorphism in the dopamine D2 receptor (DRD2) gene could be related to the response to antipsychotics. We examined the effects of the Taq1A polymorphism on the plasma monoamine metabolites during the treatment of schizophrenia with aripiprazole, a DRD2 partial agonist. Thirty Japanese patients with schizop...

journal_title：Journal of clinical psychopharmacology

authors： Miura I,Takeuchi S,Katsumi A,Mori A,Kanno K,Yang Q,Mashiko H,Numata Y,Niwa S

更新日期：2012-02-01 00:00:00

abstract：:The long-term use of the serotonin-releaser and uptake-inhibitor 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy") has been associated with memory impairments and increased liability to depressive mood and anxiety attacks. It is unclear, however, whether these psychologic deviations are reflected in alterations of t...

journal_title：Journal of clinical psychopharmacology

authors： Gamma A,Buck A,Berthold T,Vollenweider FX

更新日期：2001-02-01 00:00:00

abstract：:Alprazolam kinetics following a single 1.0-mg oral dose of alprazolam were compared between seven dialysis-dependent patients with chronic renal failure and seven healthy controls matched for age, sex, and weight. There were no significant differences between patients and controls in alprazolam half-life (11.5 vs. 11....

journal_title：Journal of clinical psychopharmacology

authors： Ochs HR,Greenblatt DJ,Labedzki L,Smith RB

更新日期：1986-10-01 00:00:00

abstract：:The current study uses utility analysis to assess economic and quality-of-life benefits of risperidone in patients with chronic schizophrenia. A retrospective analysis was performed on Positive and Negative Syndrome Symptoms (PANSS) data obtained from the published Canadian multicenter risperidone trial (part of the N...

journal_title：Journal of clinical psychopharmacology

authors： Chouinard G,Albright PS

更新日期：1997-08-01 00:00:00

abstract：:Hypersalivation is a frequent, disturbing, and uncomfortable adverse effect of clozapine therapy that frequently leads to noncompliance. The aim of this study was to examine the efficacy of metoclopramide (dopamine D2 antagonist, antiemetic medication) as an option for management of hypersalivation associated with clo...

journal_title：Journal of clinical psychopharmacology

authors： Kreinin A,Miodownik C,Mirkin V,Gaiduk Y,Yankovsky Y,Bersudsky Y,Lerner PP,Bergman J,Lerner V

更新日期：2016-06-01 00:00:00

abstract：:Dextromethorphan is a nonopioid antitussive metabolized by cytochrome P450 2D6 (CYP2D6) to an active metabolite, dextrorphan. CYP2D6 is polymorphically expressed in humans, with 5 to 10% of Caucasians being homozygous deficient for the active form of the enzyme. In a pilot study, the authors investigated the pharmacol...

journal_title：Journal of clinical psychopharmacology

authors： Zawertailo LA,Kaplan HL,Busto UE,Tyndale RF,Sellers EM

更新日期：1998-08-01 00:00:00

abstract：PURPOSE/BACKGROUND:The Phase 3 program for RBP-7000, a once-monthly subcutaneous (SC) extended-release risperidone formulation approved for treatment of schizophrenia, consisted of a double-blind placebo-controlled trial (previously reported) and a 52-week open-label study of monthly RBP-7000 120 mg. The primary object...

journal_title：Journal of clinical psychopharmacology

authors： Andorn A,Graham J,Csernansky J,Newcomer JW,Shinde S,Muma G,Heidbreder C,Fava M

更新日期：2019-09-01 00:00:00

abstract：:Quetiapine (QTP) combined with lithium (Li) or divalproex (DVP) for the treatment of mania was evaluated in 2 double-blind, placebo-controlled studies. Patients were randomized to 3 or 6 weeks of treatment with QTP plus Li/DVP or placebo (PBO) plus Li/DVP. Quetiapine was dosed up to 800 mg/d; Li was dosed to achieve s...

journal_title：Journal of clinical psychopharmacology

authors： Yatham LN,Paulsson B,Mullen J,Vågerö AM

更新日期：2004-12-01 00:00:00

abstract：:Serum neuroleptic activity by radioreceptor assay and prolactin concentration were measured every 6 months for 2 years in 105 male schizophrenic outpatients. The patients took a variety of neuroleptics at clinically determined doses. As expected, when four dissimilar neuroleptics were examined together, there was no s...

journal_title：Journal of clinical psychopharmacology

authors： Young AS,Faraone SV,Brown WA

更新日期：1989-10-01 00:00:00

abstract：:In a multicenter study of 78 severely depressed inpatients (44 women and 34 men; age range, 23 to 70 years), the efficacy, onset of efficacy, and tolerability of the reversible monoamine oxidase-A inhibitor moclobemide (450 mg/day) in combination with thioridazine (100 mg/day) were compared with those of moclobemide (...

journal_title：Journal of clinical psychopharmacology

authors： Stabl M,Kasas A,Blajev B,Bajetta G,Zöchling R,Holsboer-Trachsler E,Realini R,Schäublin-Loidl M

更新日期：1995-08-01 00:00:00